PL2612926T3 - Metody wykorzystania mirna do wykrywania śmierci komórkowej in vivo - Google Patents
Metody wykorzystania mirna do wykrywania śmierci komórkowej in vivoInfo
- Publication number
- PL2612926T3 PL2612926T3 PL13161985T PL13161985T PL2612926T3 PL 2612926 T3 PL2612926 T3 PL 2612926T3 PL 13161985 T PL13161985 T PL 13161985T PL 13161985 T PL13161985 T PL 13161985T PL 2612926 T3 PL2612926 T3 PL 2612926T3
- Authority
- PL
- Poland
- Prior art keywords
- mirna
- detection
- methods
- cell death
- vivo cell
- Prior art date
Links
- 230000030833 cell death Effects 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000001727 in vivo Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 108091070501 miRNA Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Virology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US96587107P | 2007-08-22 | 2007-08-22 | |
| EP13161985.0A EP2612926B1 (en) | 2007-08-22 | 2008-08-22 | Methods of using mirna for detection of in vivo cell death |
| EP08795523.3A EP2195450B2 (en) | 2007-08-22 | 2008-08-22 | Methods of using mirna for detection of in vivo cell death |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL2612926T3 true PL2612926T3 (pl) | 2018-07-31 |
Family
ID=40378881
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL13161985T PL2612926T3 (pl) | 2007-08-22 | 2008-08-22 | Metody wykorzystania mirna do wykrywania śmierci komórkowej in vivo |
| PL08795523T PL2195450T3 (pl) | 2007-08-22 | 2008-08-22 | Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL08795523T PL2195450T3 (pl) | 2007-08-22 | 2008-08-22 | Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki |
Country Status (16)
| Country | Link |
|---|---|
| US (4) | US8486626B2 (enExample) |
| EP (2) | EP2612926B1 (enExample) |
| JP (1) | JP5416110B2 (enExample) |
| CN (2) | CN101861399B (enExample) |
| AU (2) | AU2008289447B2 (enExample) |
| CA (1) | CA2696403C (enExample) |
| CY (1) | CY1114111T1 (enExample) |
| DK (2) | DK2612926T3 (enExample) |
| ES (2) | ES2660785T3 (enExample) |
| HR (1) | HRP20130618T1 (enExample) |
| HU (1) | HUE019019T5 (enExample) |
| NO (1) | NO2612926T3 (enExample) |
| PL (2) | PL2612926T3 (enExample) |
| PT (2) | PT2612926T (enExample) |
| TR (1) | TR201802758T4 (enExample) |
| WO (1) | WO2009025852A2 (enExample) |
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009132273A2 (en) * | 2008-04-25 | 2009-10-29 | Merck & Co., Inc. | Microrna biomarkers of tissue injury |
| WO2010004562A2 (en) * | 2008-07-09 | 2010-01-14 | Rosetta Genomics Ltd. | Methods and compositions for detecting colorectal cancer |
| ES2532153T3 (es) * | 2008-07-18 | 2015-03-24 | Trovagene, Inc. | Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR |
| CA2757711A1 (en) * | 2009-04-14 | 2010-10-21 | Merck Sharp & Dohme Corp. | Microrna as a biomarker of pancreatic islet beta-cell engagement |
| CA2767616A1 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
| EP3118334A1 (en) * | 2009-11-04 | 2017-01-18 | DiamiR, LLC | Methods of using small rna from bodily fluids for diagnosis and monitoring of neurodegenerative diseases |
| JP2013509883A (ja) | 2009-11-06 | 2013-03-21 | ザ ボード オブ トラスティーズ オブ ザ リーランド スタンフォード ジュニア ユニバーシティ | 臓器移植患者における移植片拒絶反応の非侵襲的診断方法 |
| WO2011143659A2 (en) * | 2010-05-14 | 2011-11-17 | Fluidigm Corporation | Nucleic acid isolation methods |
| JP6211511B2 (ja) * | 2011-04-18 | 2017-10-11 | ディアミール, エルエルシーDiamir, Llc | miRNAに基づくユニバーサルスクリーニングテスト(UST) |
| CN102188719B (zh) * | 2011-05-12 | 2012-12-19 | 南方医科大学 | EB病毒miR-BART3反义寡聚核苷酸在制备治疗鼻咽癌的药物中的应用 |
| US9771617B2 (en) * | 2011-06-27 | 2017-09-26 | Eisai R&D Management Co., Ltd. | Microrna biomarkers indicative of alzheimer's disease |
| WO2013022953A2 (en) * | 2011-08-08 | 2013-02-14 | Eugenia Wang | Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof |
| CA3067612A1 (en) * | 2011-09-22 | 2013-03-28 | Lineage Biosciences, Inc. | Compositions and methods for analyzing heterogeneous samples |
| ITRM20110685A1 (it) | 2011-12-23 | 2013-06-24 | Internat Ct For Genetic En Gineering And | Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci |
| HK1211624A1 (en) * | 2012-01-27 | 2016-05-27 | The Board Of Trustees Of The University Of The Leland Stanford Junior University | Methods for profiling and quantitating cell-free rna |
| US20140087964A1 (en) * | 2012-09-24 | 2014-03-27 | University Of Virginia Patent Foundation | Compositions and methods for detecting aberrant regulation, expression, and levels of hgh |
| CN104903468B (zh) * | 2012-11-16 | 2019-04-23 | 萨尔大学 | 用于帕金森氏病的新诊断MiRNA标志物 |
| EP2733219B1 (en) | 2012-11-16 | 2017-09-20 | Siemens Aktiengesellschaft | Diagnostic miRNA markers for Alzheimer |
| EP2733220B1 (en) | 2012-11-16 | 2017-10-18 | Siemens Aktiengesellschaft | Novel miRNA as a diagnostic marker for Alzheimer's Disease |
| CN103045596A (zh) * | 2012-12-20 | 2013-04-17 | 徐勇 | 唐氏综合征21号染色体相关miRNA、基因、筛选方法和应用 |
| CN103045736B (zh) * | 2012-12-20 | 2014-09-17 | 徐勇 | 唐氏综合征21号染色体miRNA差异表达图谱模型、构建方法及应用 |
| EP2759602A1 (en) | 2013-01-25 | 2014-07-30 | Charité - Universitätsmedizin Berlin | Non-invasive prenatal genetic diagnostic methods |
| DK2970958T3 (en) | 2013-03-15 | 2018-02-19 | Lineage Biosciences Inc | METHODS FOR SEQUENCING THE IMMUN REPERTOIR |
| WO2015073972A1 (en) | 2013-11-18 | 2015-05-21 | Diamir, Llc | METHODS OF USING mIRNAs FROM BODILY FLUIDS FOR DETECTION AND MONITORING OF PARKINSON'S DISEASE (PD) |
| US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
| US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
| US11062789B2 (en) | 2014-07-18 | 2021-07-13 | The Chinese University Of Hong Kong | Methylation pattern analysis of tissues in a DNA mixture |
| EP4450636A3 (en) | 2015-05-18 | 2025-01-01 | Karius, Inc. | Compositions and methods for enriching populations of nucleic acids |
| US10428391B2 (en) | 2015-07-27 | 2019-10-01 | The Johns Hopkins University | Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: PCR and sequencing based process methods |
| CN108026570A (zh) * | 2015-09-11 | 2018-05-11 | 康宁股份有限公司 | 从血液样品中纯化核酸的组合物和方法 |
| US10975436B2 (en) | 2016-01-05 | 2021-04-13 | Diamir, Llc | Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders |
| US11149313B2 (en) | 2016-03-21 | 2021-10-19 | Diamir, Llc | Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases |
| WO2018045359A1 (en) * | 2016-09-02 | 2018-03-08 | Karius, Inc. | Detection and treatment of infection during pregnancy |
| CA3043709A1 (en) | 2016-11-14 | 2018-05-17 | Berg Llc | Methods for treating parkinson's disease |
| WO2018099418A1 (en) | 2016-11-30 | 2018-06-07 | The Chinese University Of Hong Kong | Analysis of cell-free dna in urine and other samples |
| US10907211B1 (en) | 2017-02-16 | 2021-02-02 | Quantgene Inc. | Methods and compositions for detecting cancer biomarkers in bodily fluids |
| US10781487B2 (en) | 2017-07-24 | 2020-09-22 | Diamir, Llc | miRNA-based methods for detecting and monitoring aging |
| GB2612911B (en) | 2019-02-14 | 2023-11-22 | Mirvie Inc | Methods and systems for determining a pregnancy-related state of a subject |
| CN114449954B (zh) * | 2019-10-29 | 2025-05-02 | 国立研究开发法人国立循环器病研究中心 | 脑梗塞治疗辅助系统 |
| US11475981B2 (en) | 2020-02-18 | 2022-10-18 | Tempus Labs, Inc. | Methods and systems for dynamic variant thresholding in a liquid biopsy assay |
| US11211147B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing |
| US11211144B2 (en) | 2020-02-18 | 2021-12-28 | Tempus Labs, Inc. | Methods and systems for refining copy number variation in a liquid biopsy assay |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| US5856088A (en) | 1989-07-11 | 1999-01-05 | Gen-Probe Incorporated | Detection of human immunodeficiency virus type 1 |
| US5168039A (en) | 1990-09-28 | 1992-12-01 | The Board Of Trustees Of The University Of Arkansas | Repetitive DNA sequence specific for mycobacterium tuberculosis to be used for the diagnosis of tuberculosis |
| US6020124A (en) | 1992-04-27 | 2000-02-01 | Trustees Of Dartmouth College | Detection of soluble gene sequences in biological fluids |
| US5770366A (en) | 1993-07-20 | 1998-06-23 | Boehringer Mannheim Gmbh | Melanoma-inhibiting protein |
| WO1995004140A1 (en) | 1993-07-28 | 1995-02-09 | Akzo Nobel N.V. | Process for isolating nucleic acid from gram positive microorganisms |
| AU689815B2 (en) | 1993-08-30 | 1998-04-09 | Promega Corporation | Nucleic acid purification compositions and methods |
| US5631130A (en) | 1994-05-13 | 1997-05-20 | Abbott Laboratories | Materials and methods for the detection of Mycobacterium tuberculosis |
| RU2204608C2 (ru) | 1994-06-09 | 2003-05-20 | Инноженетик Н.В. | Способ выявления устойчивости микобактерий к рифампицину с возможной их идентификацией, способ гибридизации, зонд и композиция для его осуществления, набор праймеров (варианты) |
| US5731150A (en) | 1995-11-01 | 1998-03-24 | Chiron Diagnostic Corporation | IS6110 based molecular detection of mycobacterium tuberculosis |
| US6027945A (en) | 1997-01-21 | 2000-02-22 | Promega Corporation | Methods of isolating biological target materials using silica magnetic particles |
| US20020119478A1 (en) | 1997-05-30 | 2002-08-29 | Diagen Corporation | Methods for detection of nucleic acid sequences in urine |
| DE69841989D1 (de) | 1997-05-30 | 2010-12-16 | Trovagene Inc | Verfahren zur Bestimmung von Nukleinsäuresequenzen in Urin |
| US6492144B1 (en) | 1997-05-30 | 2002-12-10 | Diagen Corporation | Methods for detection of nucleic acid sequences in urine |
| US5962665A (en) | 1997-06-16 | 1999-10-05 | Abbott Laboratories | Nucleic acid primers and probes for detecting HIV-1 and HIV-2 |
| US20060204989A1 (en) * | 1998-09-22 | 2006-09-14 | Kopreski Michael S | Comparative analysis of extracellular RNA species |
| US7196183B2 (en) | 2001-08-31 | 2007-03-27 | Innogenetics N.V. | Hepatitis C virus genotype, and its use as prophylactic, therapeutic and diagnostic agent |
| US20040053264A1 (en) | 2002-02-01 | 2004-03-18 | Park Sung Sup | Clinical panel assay using DNA chips |
| EP2290071B1 (en) * | 2004-05-28 | 2014-12-31 | Asuragen, Inc. | Methods and compositions involving microRNA |
| ITRM20050067A1 (it) | 2005-02-17 | 2006-08-18 | Istituto Naz Per Le Malattie I | Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine. |
| AU2006214444B8 (en) | 2005-02-17 | 2012-04-05 | Trovagene, Inc. | Compositions and methods for detecting pathogen specific nucleic acids in urine |
| EP1856295B1 (en) | 2005-02-17 | 2013-04-03 | TrovaGene, Inc. | Compositions and methods for detecting viral specific nucleic acids in urine |
| US7914982B2 (en) | 2005-02-17 | 2011-03-29 | Trovagene, Inc. | Methods for detecting pathogen specific nucleic acids in urine |
| ITRM20050068A1 (it) | 2005-02-17 | 2006-08-18 | Istituto Naz Per Le Malattie I | Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine. |
| US20060292616A1 (en) * | 2005-06-23 | 2006-12-28 | U.S. Genomics, Inc. | Single molecule miRNA-based disease diagnostic methods |
| DE102005059315A1 (de) * | 2005-12-09 | 2007-06-14 | Qiagen Gmbh | Verfahren zur Anreicherung von kurzkettigen Nukleinsäuren |
| US20070202511A1 (en) * | 2006-02-28 | 2007-08-30 | Sigma-Aldrich Co. | Methods and compositions for the rapid isolation of small RNA molecules |
| ES2532153T3 (es) | 2008-07-18 | 2015-03-24 | Trovagene, Inc. | Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR |
-
2008
- 2008-08-22 CN CN200880113585.0A patent/CN101861399B/zh not_active Expired - Fee Related
- 2008-08-22 EP EP13161985.0A patent/EP2612926B1/en not_active Not-in-force
- 2008-08-22 CA CA2696403A patent/CA2696403C/en not_active Expired - Fee Related
- 2008-08-22 AU AU2008289447A patent/AU2008289447B2/en not_active Ceased
- 2008-08-22 JP JP2010521887A patent/JP5416110B2/ja not_active Expired - Fee Related
- 2008-08-22 CN CN201510649676.8A patent/CN105400868B/zh not_active Expired - Fee Related
- 2008-08-22 HU HUE08795523A patent/HUE019019T5/en unknown
- 2008-08-22 WO PCT/US2008/009991 patent/WO2009025852A2/en not_active Ceased
- 2008-08-22 PL PL13161985T patent/PL2612926T3/pl unknown
- 2008-08-22 NO NO13161985A patent/NO2612926T3/no unknown
- 2008-08-22 DK DK13161985.0T patent/DK2612926T3/en active
- 2008-08-22 PT PT131619850T patent/PT2612926T/pt unknown
- 2008-08-22 ES ES13161985.0T patent/ES2660785T3/es active Active
- 2008-08-22 EP EP08795523.3A patent/EP2195450B2/en not_active Not-in-force
- 2008-08-22 TR TR2018/02758T patent/TR201802758T4/tr unknown
- 2008-08-22 PL PL08795523T patent/PL2195450T3/pl unknown
- 2008-08-22 ES ES08795523.3T patent/ES2415245T5/es active Active
- 2008-08-22 DK DK08795523.3T patent/DK2195450T4/en active
- 2008-08-22 HR HRP20130618AT patent/HRP20130618T1/hr unknown
- 2008-08-22 PT PT87955233T patent/PT2195450E/pt unknown
- 2008-08-22 US US12/229,378 patent/US8486626B2/en not_active Expired - Fee Related
-
2013
- 2013-07-03 CY CY20131100546T patent/CY1114111T1/el unknown
- 2013-07-16 US US13/942,706 patent/US20150197805A1/en not_active Abandoned
-
2014
- 2014-08-11 AU AU2014210676A patent/AU2014210676B2/en not_active Ceased
-
2017
- 2017-01-06 US US15/400,157 patent/US20180135126A1/en not_active Abandoned
-
2018
- 2018-09-21 US US16/138,338 patent/US20200283851A1/en not_active Abandoned
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