PL2195450T3 - Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki - Google Patents

Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki

Info

Publication number
PL2195450T3
PL2195450T3 PL08795523T PL08795523T PL2195450T3 PL 2195450 T3 PL2195450 T3 PL 2195450T3 PL 08795523 T PL08795523 T PL 08795523T PL 08795523 T PL08795523 T PL 08795523T PL 2195450 T3 PL2195450 T3 PL 2195450T3
Authority
PL
Poland
Prior art keywords
mirna
detection
methods
cell death
vivo cell
Prior art date
Application number
PL08795523T
Other languages
English (en)
Inventor
Eugene M Shekhtman
Hovsep S Melkonyan
Samuil R Umansky
Vladimir S Scheinker
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40378881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2195450(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trovagene Inc filed Critical Trovagene Inc
Publication of PL2195450T3 publication Critical patent/PL2195450T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PL08795523T 2007-08-22 2008-08-22 Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki PL2195450T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96587107P 2007-08-22 2007-08-22
EP08795523.3A EP2195450B2 (en) 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death
PCT/US2008/009991 WO2009025852A2 (en) 2007-08-22 2008-08-22 Methods of using mirna for detection of in vivo cell death

Publications (1)

Publication Number Publication Date
PL2195450T3 true PL2195450T3 (pl) 2013-09-30

Family

ID=40378881

Family Applications (2)

Application Number Title Priority Date Filing Date
PL13161985T PL2612926T3 (pl) 2007-08-22 2008-08-22 Metody wykorzystania mirna do wykrywania śmierci komórkowej in vivo
PL08795523T PL2195450T3 (pl) 2007-08-22 2008-08-22 Sposób zastosowania miRNA do wykrywania in vivo śmierci komórki

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL13161985T PL2612926T3 (pl) 2007-08-22 2008-08-22 Metody wykorzystania mirna do wykrywania śmierci komórkowej in vivo

Country Status (17)

Country Link
US (4) US8486626B2 (pl)
EP (2) EP2612926B1 (pl)
JP (1) JP5416110B2 (pl)
CN (2) CN101861399B (pl)
AU (2) AU2008289447B2 (pl)
CA (1) CA2696403C (pl)
CY (1) CY1114111T1 (pl)
DK (2) DK2195450T4 (pl)
ES (2) ES2660785T3 (pl)
HK (1) HK1218767A1 (pl)
HR (1) HRP20130618T1 (pl)
HU (1) HUE019019T5 (pl)
NO (1) NO2612926T3 (pl)
PL (2) PL2612926T3 (pl)
PT (2) PT2612926T (pl)
TR (1) TR201802758T4 (pl)
WO (1) WO2009025852A2 (pl)

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WO2013022953A2 (en) * 2011-08-08 2013-02-14 Eugenia Wang Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof
US20150211070A1 (en) * 2011-09-22 2015-07-30 Immu-Metrix, Llc Compositions and methods for analyzing heterogeneous samples
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
SG11201505515XA (en) * 2012-01-27 2015-09-29 Univ Leland Stanford Junior Methods for profiling and quantitating cell-free rna
US20140087964A1 (en) * 2012-09-24 2014-03-27 University Of Virginia Patent Foundation Compositions and methods for detecting aberrant regulation, expression, and levels of hgh
EP2733220B1 (en) * 2012-11-16 2017-10-18 Siemens Aktiengesellschaft Novel miRNA as a diagnostic marker for Alzheimer's Disease
WO2014075822A1 (en) * 2012-11-16 2014-05-22 Siemens Aktiengesellschaft New diagnostic mirna markers for parkinson disease
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US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
EP3889272A1 (en) 2014-07-18 2021-10-06 The Chinese University of Hong Kong Methylation pattern analysis of tissues in dna mixture
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US10428391B2 (en) 2015-07-27 2019-10-01 The Johns Hopkins University Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: PCR and sequencing based process methods
WO2017044710A1 (en) * 2015-09-11 2017-03-16 Corning Incorporated Compositions and methods for nucleic acid purification from blood samples
US10975436B2 (en) 2016-01-05 2021-04-13 Diamir, Llc Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders
US11149313B2 (en) 2016-03-21 2021-10-19 Diamir, Llc Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases
WO2018045359A1 (en) * 2016-09-02 2018-03-08 Karius, Inc. Detection and treatment of infection during pregnancy
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JP2020503003A (ja) 2016-11-30 2020-01-30 ザ チャイニーズ ユニバーシティ オブ ホンコン 尿および他のサンプルにおける無細胞ｄｎａの分析
US10907211B1 (en) 2017-02-16 2021-02-02 Quantgene Inc. Methods and compositions for detecting cancer biomarkers in bodily fluids
US10781487B2 (en) 2017-07-24 2020-09-22 Diamir, Llc miRNA-based methods for detecting and monitoring aging
AU2020221278A1 (en) 2019-02-14 2021-08-05 Mirvie, Inc. Methods and systems for determining a pregnancy-related state of a subject
CN114449954A (zh) * 2019-10-29 2022-05-06 国立研究开发法人国立循环器病研究中心 脑梗塞治疗辅助系统
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
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Also Published As

Publication number Publication date
US20200283851A1 (en) 2020-09-10
PT2195450E (pt) 2013-07-10
EP2195450B2 (en) 2016-07-20
EP2612926B1 (en) 2017-11-29
US20150197805A1 (en) 2015-07-16
WO2009025852A3 (en) 2009-05-07
DK2195450T3 (da) 2013-06-24
PT2612926T (pt) 2018-03-02
EP2195450A2 (en) 2010-06-16
AU2008289447A1 (en) 2009-02-26
US20180135126A1 (en) 2018-05-17
CN105400868A (zh) 2016-03-16
US8486626B2 (en) 2013-07-16
CA2696403C (en) 2018-01-02
CN105400868B (zh) 2021-03-26
ES2415245T5 (es) 2016-12-23
ES2660785T3 (es) 2018-03-26
CN101861399B (zh) 2015-11-25
WO2009025852A2 (en) 2009-02-26
PL2612926T3 (pl) 2018-07-31
AU2008289447B2 (en) 2014-09-04
CY1114111T1 (el) 2016-07-27
DK2612926T3 (en) 2018-03-12
ES2415245T3 (es) 2013-07-24
EP2195450B1 (en) 2013-04-03
HUE019019T5 (en) 2017-04-28
AU2014210676A1 (en) 2014-08-28
CA2696403A1 (en) 2009-02-26
DK2195450T4 (en) 2016-10-24
US20090081640A1 (en) 2009-03-26
EP2612926A1 (en) 2013-07-10
CN101861399A (zh) 2010-10-13
NO2612926T3 (pl) 2018-04-28
AU2014210676B2 (en) 2017-04-06
TR201802758T4 (tr) 2018-03-21
HRP20130618T1 (en) 2013-07-31
JP5416110B2 (ja) 2014-02-12
HK1218767A1 (zh) 2017-03-10
JP2010536372A (ja) 2010-12-02

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