SG10201405455UA - Cells and methods for obtaining them - Google Patents

Cells and methods for obtaining them

Info

Publication number
SG10201405455UA
SG10201405455UA SG10201405455UA SG10201405455UA SG10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA SG 10201405455U A SG10201405455U A SG 10201405455UA
Authority
SG
Singapore
Prior art keywords
cells
obtaining
methods
Prior art date
Application number
SG10201405455UA
Inventor
Pentao Liu
Wei Wang
Jiang Yang
Original Assignee
Genome Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genome Res Ltd filed Critical Genome Res Ltd
Publication of SG10201405455UA publication Critical patent/SG10201405455UA/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/20—Cytokines; Chemokines
    • C12N2501/23—Interleukins [IL]
    • C12N2501/235—Leukemia inhibitory factor [LIF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/385—Hormones with nuclear receptors of the family of the retinoic acid recptor, e.g. RAR, RXR; Peroxisome proliferator-activated receptor [PPAR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/602—Sox-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/603—Oct-3/4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/604—Klf-4
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/60—Transcription factors
    • C12N2501/606—Transcription factors c-Myc
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/70—Enzymes
    • C12N2501/72—Transferases (EC 2.)
    • C12N2501/727—Kinases (EC 2.7.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
SG10201405455UA 2009-09-07 2010-09-07 Cells and methods for obtaining them SG10201405455UA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US24028209P 2009-09-07 2009-09-07
GBGB0915523.5A GB0915523D0 (en) 2009-09-07 2009-09-07 Cells and methods for obtaining them
US27620309P 2009-09-08 2009-09-08

Publications (1)

Publication Number Publication Date
SG10201405455UA true SG10201405455UA (en) 2014-10-30

Family

ID=41203246

Family Applications (2)

Application Number Title Priority Date Filing Date
SG2012015343A SG178613A1 (en) 2009-09-07 2010-09-07 Cells and methods for obtaining them
SG10201405455UA SG10201405455UA (en) 2009-09-07 2010-09-07 Cells and methods for obtaining them

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SG2012015343A SG178613A1 (en) 2009-09-07 2010-09-07 Cells and methods for obtaining them

Country Status (8)

Country Link
US (1) US9512407B2 (en)
EP (1) EP2475774A1 (en)
JP (1) JP5944315B2 (en)
CN (1) CN102822345B (en)
CA (1) CA2773291A1 (en)
GB (1) GB0915523D0 (en)
SG (2) SG178613A1 (en)
WO (1) WO2011027180A1 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SG10201406139RA (en) 2009-09-30 2014-11-27 Agency Science Tech & Res A nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells
CA2814713A1 (en) * 2010-10-14 2012-04-19 University Of Central Florida Research Foundation, Inc. Cardiac induced pluripotent stem cells and methods of use in repair and regeneration of myocardium
GB2496375A (en) 2011-10-28 2013-05-15 Kymab Ltd A non-human assay vertebrate comprising human antibody loci and human epitope knock-in, and uses thereof
GB201122047D0 (en) 2011-12-21 2012-02-01 Kymab Ltd Transgenic animals
CA2924735C (en) * 2013-09-20 2023-02-28 Lonza Ltd Methods for nuclear reprogramming of cells
EP3384007B1 (en) * 2015-11-30 2024-03-27 Beihao Stem Cell and Regenerative Medicine Research Institute Co., Ltd. Improved methods for reprograming non-pluripotent cells into pluripotent stem cells
CN109750000A (en) * 2017-11-06 2019-05-14 内蒙古赛科星家畜种业与繁育生物技术研究院有限公司 Novel animal cell line R6-MEFs method and purposes are prepared using XistTale inhibition transcription factor R6
CN109913494A (en) * 2019-02-12 2019-06-21 北京呈诺医学科技有限公司 A kind of abductive approach of new ips cell
CN110218741B (en) * 2019-05-31 2020-12-25 华中农业大学 Method for synchronously activating transcription activities of multiple porcine endogenous stem cell factors by adopting tandem sgRNAs
CN110592014A (en) * 2019-08-14 2019-12-20 广东美赛尔细胞生物科技有限公司 Method for continuously removing feeder cells in vitro and in vivo without irradiation in NK cell therapy
CN114703227B (en) * 2022-01-27 2023-11-10 中国科学院生态环境研究中心 RAR alpha effect in vitro screening method constructed based on MCF-7 cell line

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0683227A1 (en) 1989-06-30 1995-11-22 Institut National De La Sante Et De La Recherche Medicale (Inserm) Human retinoic acid receptor and genes encoding for it
US5663303A (en) 1991-11-04 1997-09-02 Institut National De La Sante Et De La Recherche Medicale Antibodies specific for retinoic acid receptor-γ
ATE303360T1 (en) 2000-04-28 2005-09-15 Hoffmann La Roche P-(SULFONYL)-ARYL- AND -HETEROARYL-AMINE
US20070224615A1 (en) * 2003-07-09 2007-09-27 Invitrogen Corporation Methods for assaying protein-protein interactions
US7476673B2 (en) 2003-12-30 2009-01-13 Allergan, Inc. Disubstituted chalcone oximes as selective agonists of RARγ retinoid receptors
WO2005080973A1 (en) 2004-02-13 2005-09-01 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with human nuclear receptor nr5a1 (nr5a1)
WO2005082344A1 (en) 2004-02-24 2005-09-09 Smithkline Beecham Corporation Lhr1 activators as medicaments
CN101313065A (en) 2005-08-01 2008-11-26 纽珀滕索有限公司 Production of reprogrammed cells with restored potential
EP2206724A1 (en) * 2005-12-13 2010-07-14 Kyoto University Nuclear reprogramming factor
WO2008064136A2 (en) 2006-11-17 2008-05-29 Acadia Pharmaceuticals Inc. Compounds with activity at retinoic acid receptors
EP2219652B1 (en) 2007-11-16 2012-04-25 Baylor College Of Medicine Phospholipid compositions and uses thereof
US9683232B2 (en) 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
JP5558097B2 (en) 2007-12-10 2014-07-23 国立大学法人京都大学 Efficient nuclear initialization method
CN101250502A (en) * 2008-04-01 2008-08-27 中国科学院上海生命科学研究院 Method for preparing evoked pluripotent stem cell
SG10201406139RA (en) * 2009-09-30 2014-11-27 Agency Science Tech & Res A nuclear receptor and mutant thereof and the use of the same in the reprogramming of cells

Also Published As

Publication number Publication date
CN102822345A (en) 2012-12-12
CA2773291A1 (en) 2011-03-10
US9512407B2 (en) 2016-12-06
SG178613A1 (en) 2012-04-27
WO2011027180A1 (en) 2011-03-10
GB0915523D0 (en) 2009-10-07
JP2013503622A (en) 2013-02-04
JP5944315B2 (en) 2016-07-05
EP2475774A1 (en) 2012-07-18
US20120315703A1 (en) 2012-12-13
CN102822345B (en) 2016-06-08

Similar Documents

Publication Publication Date Title
IL272848B (en) Methods for reprogramming cells and uses thereof
HK1249547A1 (en) Fucosylation-deficient cells
EP2391711A4 (en) Novel cell lines and methods
GB0908613D0 (en) T Cell Reseptors
EP2457078A4 (en) Nanofluidic cell
PL2485525T3 (en) Method and device for performing space coordination among cells
EP2468850A4 (en) Cell preservation method
EP2445034A4 (en) Battery and method for producing battery
SG10201405455UA (en) Cells and methods for obtaining them
GB0909645D0 (en) Methods
GB0907350D0 (en) Methods
GB0901001D0 (en) Methods
GB0912685D0 (en) Methods
EP2483391A4 (en) Methods and kits for cell release
EP2499265A4 (en) Device and method for culturing cells
GB0920775D0 (en) Cells
GB0912744D0 (en) Methods and uses
EP2470022A4 (en) Compounds and methods
GB0912159D0 (en) Methods
GB0909380D0 (en) Method and use
GB0920256D0 (en) Elecrochemical cells and components thereof
HUE052153T2 (en) Fucosylation-deficient cells
GB0901675D0 (en) Cells
GB0908223D0 (en) Cells
GB0920035D0 (en) Cell