DE69841989D1 - Verfahren zur Bestimmung von Nukleinsäuresequenzen in Urin - Google Patents

Verfahren zur Bestimmung von Nukleinsäuresequenzen in Urin

Info

Publication number
DE69841989D1
DE69841989D1 DE69841989T DE69841989T DE69841989D1 DE 69841989 D1 DE69841989 D1 DE 69841989D1 DE 69841989 T DE69841989 T DE 69841989T DE 69841989 T DE69841989 T DE 69841989T DE 69841989 D1 DE69841989 D1 DE 69841989D1
Authority
DE
Germany
Prior art keywords
nucleic acid
acid sequence
urine sample
urine
acid sequences
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69841989T
Other languages
English (en)
Inventor
Anatoly V Lichtenstein
Samuil R Umansky
Hovsep S Melkonyan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cardiff Oncology Inc
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trovagene Inc filed Critical Trovagene Inc
Application granted granted Critical
Publication of DE69841989D1 publication Critical patent/DE69841989D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
DE69841989T 1997-05-30 1998-05-29 Verfahren zur Bestimmung von Nukleinsäuresequenzen in Urin Expired - Lifetime DE69841989D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4817097P 1997-05-30 1997-05-30
US4838197P 1997-06-30 1997-06-30

Publications (1)

Publication Number Publication Date
DE69841989D1 true DE69841989D1 (de) 2010-12-16

Family

ID=26725864

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69841989T Expired - Lifetime DE69841989D1 (de) 1997-05-30 1998-05-29 Verfahren zur Bestimmung von Nukleinsäuresequenzen in Urin
DE69833856T Expired - Lifetime DE69833856T2 (de) 1997-05-30 1998-05-29 Verfahren zur bestimmung von nukleinsäuresequenzen in urin

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69833856T Expired - Lifetime DE69833856T2 (de) 1997-05-30 1998-05-29 Verfahren zur bestimmung von nukleinsäuresequenzen in urin

Country Status (11)

Country Link
US (2) US6251638B1 (de)
EP (3) EP0920539B9 (de)
AT (3) ATE320505T1 (de)
AU (1) AU7703998A (de)
CY (1) CY1113124T1 (de)
DE (2) DE69841989D1 (de)
DK (3) DK2216416T3 (de)
ES (3) ES2355631T3 (de)
HK (1) HK1088363A1 (de)
PT (1) PT2216416E (de)
WO (1) WO1998054364A1 (de)

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US7041805B2 (en) * 1998-09-01 2006-05-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1201755A1 (de) * 1999-07-30 2002-05-02 Mitsubishi Pharma Corporation Gen des humanen pgt aus dem gehirn
JP4018304B2 (ja) * 1999-08-27 2007-12-05 独立行政法人科学技術振興機構 高親和性コリントランスポーター
WO2001023550A2 (en) * 1999-09-29 2001-04-05 Diagnocure Inc. Pca3 messenger rna species in benign and malignant prostate tissues
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US7029840B2 (en) * 2000-11-15 2006-04-18 Becton, Dickinson And Company Method for preservation of cells and nucleic acid targets
AU2002243263A1 (en) * 2000-11-15 2002-07-24 Roche Diagnostics Corporation Methods and reagents for identifying rare fetal cells in the material circulation
WO2002059316A2 (en) * 2001-01-23 2002-08-01 Lexicon Genetics Incorporated Human ion exchanger proteins and polynucleotides encoding the same
US20030144196A1 (en) * 2001-08-21 2003-07-31 Bowen Michael A. Activated T lymphocyte nucleic acid sequences and polypeptides encoded by same
WO2003062441A1 (en) * 2002-01-18 2003-07-31 Genzyme Corporation Methods for fetal dna detection and allele quantitation
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US7217515B2 (en) * 2002-09-30 2007-05-15 Chi Mei Foundation Medical Center HURP gene as a molecular marker for bladder cancer
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EP1584923A3 (de) * 2004-04-07 2006-01-04 Roche Diagnostics GmbH Stabilisierung von Biomolekülen in Proben
WO2005111244A2 (en) * 2004-05-10 2005-11-24 Exact Sciences Corporation Methods for detecting a mutant nucleic acid
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WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
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WO2006088895A2 (en) * 2005-02-17 2006-08-24 Istituto Nazionale Per Le Malattie Infettive Irccs Lazzaro Spallanzani Compositions and methods for detecting pathogen specific nucleic acids in urine
ITRM20050068A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
ITRM20050067A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
US7914982B2 (en) * 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
US7449297B2 (en) * 2005-04-14 2008-11-11 Euclid Diagnostics Llc Methods of copying the methylation pattern of DNA during isothermal amplification and microarrays
US9777314B2 (en) * 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
NZ545243A (en) * 2006-02-10 2009-07-31 Pacific Edge Biotechnology Ltd Urine gene expression ratios for detection of cancer
ES2391212T3 (es) * 2006-12-07 2012-11-22 Novartis Ag Cribado genético prenatal no-invasivo
WO2008075790A2 (en) * 2006-12-20 2008-06-26 Olympus Corporation Method for detecting cancer with nucleic acids in blood
ES2660785T3 (es) * 2007-08-22 2018-03-26 Trovagene, Inc. Métodos de uso de ARNmi para la detección de la muerte de células in vivo
US20100285469A1 (en) * 2007-10-10 2010-11-11 Philadelphia Health & Education d/b/a Drexel University College of Medicine Method of tumor screening
US20110171640A1 (en) * 2008-02-12 2011-07-14 Novartis Vaccines And Diagnostics, Inc. Method for isolating cell free apoptotic or fetal nucleic acids
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Also Published As

Publication number Publication date
EP1634966B1 (de) 2010-11-03
DK2216416T3 (da) 2012-08-27
DE69833856T2 (de) 2006-11-23
EP1634966A3 (de) 2006-06-21
HK1088363A1 (en) 2006-11-03
EP0920539B9 (de) 2006-08-02
ES2389055T3 (es) 2012-10-22
EP0920539A4 (de) 2004-06-09
AU7703998A (en) 1998-12-30
EP2216416A1 (de) 2010-08-11
DK0920539T3 (da) 2006-07-24
ATE557103T1 (de) 2012-05-15
DE69833856D1 (de) 2006-05-11
ATE486958T1 (de) 2010-11-15
ES2260837T3 (es) 2006-11-01
EP0920539B1 (de) 2006-03-15
DK1634966T3 (da) 2011-02-07
WO1998054364A1 (en) 1998-12-03
CY1113124T1 (el) 2016-04-13
ES2355631T3 (es) 2011-03-29
EP2216416B1 (de) 2012-05-09
US6251638B1 (en) 2001-06-26
EP1634966A2 (de) 2006-03-15
EP0920539A1 (de) 1999-06-09
US6287820B1 (en) 2001-09-11
PT2216416E (pt) 2012-08-16
ATE320505T1 (de) 2006-04-15

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