DE60000583D1 - Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung - Google Patents
Verfahren zur identifizierung und/oder quantifizierung einer zielverbindungInfo
- Publication number
- DE60000583D1 DE60000583D1 DE60000583T DE60000583T DE60000583D1 DE 60000583 D1 DE60000583 D1 DE 60000583D1 DE 60000583 T DE60000583 T DE 60000583T DE 60000583 T DE60000583 T DE 60000583T DE 60000583 D1 DE60000583 D1 DE 60000583D1
- Authority
- DE
- Germany
- Prior art keywords
- target compound
- precipitate
- capture molecule
- quantifying
- identifying
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000002244 precipitate Substances 0.000 abstract 3
- 238000011002 quantification Methods 0.000 abstract 2
- 230000027455 binding Effects 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/47—Scattering, i.e. diffuse reflection
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00608—DNA chips
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00614—Delimitation of the attachment areas
- B01J2219/00617—Delimitation of the attachment areas by chemical means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00623—Immobilisation or binding
- B01J2219/00626—Covalent
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
- B01J2219/00704—Processes involving means for analysing and characterising the products integrated with the reactor apparatus
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pathology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Materials Engineering (AREA)
- Cell Biology (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Composite Materials (AREA)
- Food Science & Technology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Photoreceptors In Electrophotography (AREA)
- Electrotherapy Devices (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99870106 | 1999-05-19 | ||
EP99870106A EP1054259A1 (de) | 1999-05-19 | 1999-05-19 | Verfahren zur Identifizierung von einer Zielverbindung |
EP00870025A EP1126272A1 (de) | 2000-02-18 | 2000-02-18 | Vorrichtung zum Nachweis und/oder Mengenbestimmung eines Niederschlags auf der Oberfläche eines festen Trägers |
EP00870025 | 2000-02-18 | ||
PCT/BE2000/000054 WO2000072018A1 (en) | 1999-05-19 | 2000-05-16 | Method for the identification and/or the quantification of a target compound |
Publications (3)
Publication Number | Publication Date |
---|---|
DE60000583D1 true DE60000583D1 (de) | 2002-11-14 |
DE60000583T2 DE60000583T2 (de) | 2003-06-26 |
DE60000583T3 DE60000583T3 (de) | 2009-04-30 |
Family
ID=26074222
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60000583T Expired - Lifetime DE60000583T3 (de) | 1999-05-19 | 2000-05-16 | Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung |
Country Status (11)
Country | Link |
---|---|
US (1) | US7321829B2 (de) |
JP (1) | JP4598960B2 (de) |
CN (1) | CN100533146C (de) |
AT (1) | ATE225940T1 (de) |
AU (1) | AU779752B2 (de) |
BR (1) | BR0011603A (de) |
CA (1) | CA2371658C (de) |
DE (1) | DE60000583T3 (de) |
ES (1) | ES2185592T5 (de) |
MX (1) | MXPA01011915A (de) |
WO (1) | WO2000072018A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6582921B2 (en) * | 1996-07-29 | 2003-06-24 | Nanosphere, Inc. | Nanoparticles having oligonucleotides attached thereto and uses thereof |
US20030096321A1 (en) * | 1999-05-19 | 2003-05-22 | Jose Remacle | Method for the identification and/or the quantification of a target compound obtained from a biological sample upon chips |
US7875442B2 (en) | 2000-03-24 | 2011-01-25 | Eppendorf Array Technologies | Identification and quantification of a plurality of biological (micro)organisms or their components |
US7829313B2 (en) | 2000-03-24 | 2010-11-09 | Eppendorf Array Technologies | Identification and quantification of a plurality of biological (micro)organisms or their components |
US7205104B2 (en) | 2000-03-24 | 2007-04-17 | Eppendorf Array Technologies Sa (Eat) | Identification of biological (micro) organisms by detection of their homologous nucleotide sequences on arrays |
US7202026B2 (en) | 2000-03-24 | 2007-04-10 | Eppendorf Array Technologies Sa (Eat) | Identification of a large number of biological (micro)organisms groups at different levels by their detection on a same array |
EP1164201A1 (de) * | 2000-06-14 | 2001-12-19 | Facultés Universitaires Notre-Dame de la Paix | Umgekehrter nachweis zur Identifizierung und/oder Quantifizierung von Nukleotid-Zielsequenzen mittels Biochips |
DE50108396D1 (de) * | 2000-07-01 | 2006-01-19 | Clondiag Chip Tech Gmbh | Verfahren zum qualitativen und/oder quantitativen nachweis von molekularen wechselwirkungen auf sonden-arrays |
EP1184349A1 (de) | 2000-09-01 | 2002-03-06 | A.S.B.L. Facultes Universitaires Notre-Dame De La Paix | Verfahren zur Erhaltung einer Oberflächenaktivierung eines festen Trägers zur Bildung von Biochips Mikroanordnungen |
DK1373573T3 (da) * | 2001-03-09 | 2014-01-20 | Trovagene Inc | Konjugatsonder og optisk detektion af analytter |
EP1412536B1 (de) * | 2001-08-03 | 2009-02-25 | Nanosphere, Inc. | Nanopartikelabbildungssystem und -verfahren |
DE10201463B4 (de) | 2002-01-16 | 2005-07-21 | Clondiag Chip Technologies Gmbh | Reaktionsgefäß zur Durchführung von Array-Verfahren |
EP1376111A1 (de) * | 2002-06-24 | 2004-01-02 | Universite Catholique De Louvain | Verfahren und Vorrichtung für die hochempfindliche Bestimmung von DNA und anderen Testsubstanzen |
DE10315074A1 (de) * | 2003-04-02 | 2004-10-14 | Clondiag Chip Technologies Gmbh | Vorrichtung zur Vervielfältigung und zum Nachweis von Nukleinsäuren |
DE102004003860A1 (de) | 2004-01-26 | 2005-08-18 | Clondiag Chip Technologies Gmbh | Verfahren zur Geno- und Pathotypisierung von Pseudomonas aeruginosa |
DE102004022263A1 (de) | 2004-05-06 | 2005-12-15 | Clondiag Chip Technologies Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
DE102005052713A1 (de) | 2005-11-04 | 2007-05-16 | Clondiag Chip Tech Gmbh | Vorrichtung und Verfahren zum Nachweis von molekularen Wechselwirkungen |
US7338763B2 (en) | 2004-06-02 | 2008-03-04 | Eppendorf Array Technologies S.A. | Method and kit for the detection and/or quantification of homologous nucleotide sequences on arrays |
DE102004056735A1 (de) | 2004-11-09 | 2006-07-20 | Clondiag Chip Technologies Gmbh | Vorrichtung für die Durchführung und Analyse von Mikroarray-Experimenten |
WO2007034924A1 (ja) * | 2005-09-22 | 2007-03-29 | Meiji Seika Kaisha, Ltd. | メタロ-β-ラクタマーゼ阻害剤 |
EP2674217B1 (de) * | 2006-11-06 | 2019-07-10 | Alere Technologies GmbH | Vorrichtung für bindungsassays |
DE102007025275A1 (de) * | 2007-05-31 | 2008-12-04 | Qiagen Gmbh | Butendisäure oder deren Derivate zur Behandlung einer biologischen Probe |
WO2009039170A2 (en) * | 2007-09-17 | 2009-03-26 | Gentel Biosurfaces, Inc. | Integrated protein chip assay |
EP2077336A1 (de) | 2007-12-19 | 2009-07-08 | Koninklijke Philips Electronics N.V. | Vorrichtung und Verfahren zur parallelen quantitativen Analyse mehrerer Nukleinsäuren |
WO2009105670A2 (en) * | 2008-02-21 | 2009-08-27 | Gentel Biosciences, Inc. | Substrates for multiplexed assays and uses thereof |
GB0809069D0 (en) | 2008-05-19 | 2008-06-25 | Univ Leuven Kath | Gene signatures |
EP2138232A1 (de) | 2008-06-23 | 2009-12-30 | Koninklijke Philips Electronics N.V. | Nachweis eingefangender Aliquoten amplifizierter Nukleinsäuren |
EP2138587A1 (de) | 2008-06-23 | 2009-12-30 | Koninklijke Philips Electronics N.V. | Nukleinsäureamplifikation unter Verwendung von Temperaturzonen |
EP2138588A1 (de) | 2008-06-23 | 2009-12-30 | Koninklijke Philips Electronics N.V. | Messung der Schmelzkurve während der Amplifizierung |
US9279770B2 (en) * | 2010-10-15 | 2016-03-08 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Mid-infrared imaging of microarrays |
EP2561102A1 (de) | 2010-12-02 | 2013-02-27 | Katholieke Universiteit Leuven K.U. Leuven R&D | Eingriffe und diagnosen in zusammenhang mit der il-rezeptor-assoziierten kinase |
EP2812704A4 (de) | 2012-02-07 | 2016-03-23 | Intuitive Biosciences Inc | Mycobakteriumstuberkulose-spezifische peptide zur erkennung einer infektion oder immunisierung nichtmenschlicher primaten |
DK3110973T3 (da) | 2014-02-27 | 2019-05-13 | Univ Leuven Kath | Oxidativt stress og kardiovaskulære sygdomshændelser |
US10704097B2 (en) | 2014-02-27 | 2020-07-07 | Katholieke Universiteit Leuven | Oxidative stress and cardiovascular disease events |
US10392601B2 (en) | 2014-12-19 | 2019-08-27 | Vrije Universiteit Brussel | In Vitro maturation of a mammalian cumulus oocyte complex |
US11459604B2 (en) | 2018-07-12 | 2022-10-04 | Luminex Corporation | Systems and methods for performing variable sample preparation and analysis processes |
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US5807522A (en) * | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
US5985356A (en) * | 1994-10-18 | 1999-11-16 | The Regents Of The University Of California | Combinatorial synthesis of novel materials |
BE1008955A3 (fr) | 1994-11-14 | 1996-10-01 | Univ Catholique Louvain | Procede d'obtention de biomateriaux et produits obtenus. |
GB9502112D0 (en) * | 1995-02-03 | 1995-03-22 | British Biocell Int | Assay device and method |
KR100306951B1 (ko) | 1995-12-05 | 2001-11-15 | 테칸 보스턴, 인코포레이티드 | 내장된정보과학에의해미세유체공학시스템내의유체유동을구동시키기위해구심가속도를이용하는장치및방법 |
US6027890A (en) * | 1996-01-23 | 2000-02-22 | Rapigene, Inc. | Methods and compositions for enhancing sensitivity in the analysis of biological-based assays |
EP0880598A4 (de) * | 1996-01-23 | 2005-02-23 | Affymetrix Inc | Verfahren zur analyse von nukleinsäure |
JP2000504575A (ja) * | 1996-02-08 | 2000-04-18 | アフィメトリックス,インコーポレイテッド | 微生物のチップベースの種分化および表現型特徴付け |
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JP4245664B2 (ja) | 1996-07-29 | 2009-03-25 | ナノスフェアー インコーポレイテッド | オリゴヌクレオチドを備えた金ナノ粒子を使用して標的該酸を検出する方法 |
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BR9814726A (pt) | 1997-12-30 | 2000-10-17 | Jose Remacle | Método compreendendo molécula de captura fixada em superficìe de disco |
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-
2000
- 2000-05-16 BR BR0011603-3A patent/BR0011603A/pt not_active IP Right Cessation
- 2000-05-16 DE DE60000583T patent/DE60000583T3/de not_active Expired - Lifetime
- 2000-05-16 AU AU47355/00A patent/AU779752B2/en not_active Expired
- 2000-05-16 CN CNB008077444A patent/CN100533146C/zh not_active Expired - Lifetime
- 2000-05-16 WO PCT/BE2000/000054 patent/WO2000072018A1/en active IP Right Grant
- 2000-05-16 ES ES00929132T patent/ES2185592T5/es not_active Expired - Lifetime
- 2000-05-16 JP JP2000620355A patent/JP4598960B2/ja not_active Expired - Lifetime
- 2000-05-16 AT AT00929132T patent/ATE225940T1/de not_active IP Right Cessation
- 2000-05-16 CA CA2371658A patent/CA2371658C/en not_active Expired - Lifetime
- 2000-05-16 MX MXPA01011915A patent/MXPA01011915A/es active IP Right Grant
- 2000-05-19 US US09/574,626 patent/US7321829B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
ATE225940T1 (de) | 2002-10-15 |
US7321829B2 (en) | 2008-01-22 |
MXPA01011915A (es) | 2003-09-04 |
BR0011603A (pt) | 2002-03-12 |
DE60000583T3 (de) | 2009-04-30 |
US20030124522A1 (en) | 2003-07-03 |
AU4735500A (en) | 2000-12-12 |
CN100533146C (zh) | 2009-08-26 |
CA2371658C (en) | 2012-01-31 |
ES2185592T5 (es) | 2009-03-01 |
AU779752B2 (en) | 2005-02-10 |
CN1351712A (zh) | 2002-05-29 |
ES2185592T3 (es) | 2003-05-01 |
JP2003500652A (ja) | 2003-01-07 |
CA2371658A1 (en) | 2000-11-30 |
DE60000583T2 (de) | 2003-06-26 |
WO2000072018A1 (en) | 2000-11-30 |
JP4598960B2 (ja) | 2010-12-15 |
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