ATE486958T1 - Verfahren zur bestimmung von nukleinsäuresequenzen in urin - Google Patents

Verfahren zur bestimmung von nukleinsäuresequenzen in urin

Info

Publication number
ATE486958T1
ATE486958T1 AT05077010T AT05077010T ATE486958T1 AT E486958 T1 ATE486958 T1 AT E486958T1 AT 05077010 T AT05077010 T AT 05077010T AT 05077010 T AT05077010 T AT 05077010T AT E486958 T1 ATE486958 T1 AT E486958T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid sequence
urine sample
urine
acid sequences
Prior art date
Application number
AT05077010T
Other languages
English (en)
Inventor
Anatoly V Lichtenstein
Samuil R Umansky
Hovsep S Melkonyan
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trovagene Inc filed Critical Trovagene Inc
Application granted granted Critical
Publication of ATE486958T1 publication Critical patent/ATE486958T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6879—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for sex determination
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05077010T 1997-05-30 1998-05-29 Verfahren zur bestimmung von nukleinsäuresequenzen in urin ATE486958T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US4817097P 1997-05-30 1997-05-30
US4838197P 1997-06-30 1997-06-30

Publications (1)

Publication Number Publication Date
ATE486958T1 true ATE486958T1 (de) 2010-11-15

Family

ID=26725864

Family Applications (3)

Application Number Title Priority Date Filing Date
AT10161334T ATE557103T1 (de) 1997-05-30 1998-05-29 Verfahren zur erkennung von nukleinsäuresequenzen in urin
AT98924998T ATE320505T1 (de) 1997-05-30 1998-05-29 Verfahren zur bestimmung von nukleinsäuresequenzen in urin
AT05077010T ATE486958T1 (de) 1997-05-30 1998-05-29 Verfahren zur bestimmung von nukleinsäuresequenzen in urin

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT10161334T ATE557103T1 (de) 1997-05-30 1998-05-29 Verfahren zur erkennung von nukleinsäuresequenzen in urin
AT98924998T ATE320505T1 (de) 1997-05-30 1998-05-29 Verfahren zur bestimmung von nukleinsäuresequenzen in urin

Country Status (10)

Country Link
US (2) US6251638B1 (de)
EP (3) EP1634966B1 (de)
AT (3) ATE557103T1 (de)
AU (1) AU7703998A (de)
CY (1) CY1113124T1 (de)
DE (2) DE69841989D1 (de)
DK (3) DK1634966T3 (de)
ES (3) ES2389055T3 (de)
PT (1) PT2216416E (de)
WO (1) WO1998054364A1 (de)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6451523B1 (en) * 1994-09-14 2002-09-17 Interneuron Pharmaceuticals, Inc. Detection of a leptin receptor variant and methods for regulating obesity
JP3981416B2 (ja) * 1997-04-10 2007-09-26 ユニバーシティ メディカル センター ナイメーヘン Ｐｃａ３タンパク質、ｐｃａ３遺伝子、及びこれらの用途
USRE39920E1 (en) * 1997-05-30 2007-11-13 Xenomics, Inc. Methods for detection of nucleic acid sequences in urine
US7060458B1 (en) * 1997-08-14 2006-06-13 Wyeth Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
US20030032102A1 (en) * 1997-09-18 2003-02-13 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7569342B2 (en) 1997-12-10 2009-08-04 Sierra Molecular Corp. Removal of molecular assay interferences
US20030068731A1 (en) * 1997-12-17 2003-04-10 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030113842A1 (en) * 1998-03-11 2003-06-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030166132A1 (en) * 1998-08-26 2003-09-04 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7041805B2 (en) * 1998-09-01 2006-05-09 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001009324A1 (fr) * 1999-07-30 2001-02-08 Mitsubishi Pharma Corporation Gene de pgt de type cerveau humain
JP4018304B2 (ja) * 1999-08-27 2007-12-05 独立行政法人科学技術振興機構 高親和性コリントランスポーター
PT1222266E (pt) * 1999-09-29 2006-07-31 Diagnocure Inc Arn mensageiro de pca3 em tecidos benignos e malignos da prostata
EP1201681A1 (de) * 2000-10-30 2002-05-02 Millennium Pharmaceuticals, Inc. "Fail" Moleküle und deren Verwendung
US7029840B2 (en) * 2000-11-15 2006-04-18 Becton, Dickinson And Company Method for preservation of cells and nucleic acid targets
EP1368369A4 (de) * 2000-11-15 2006-02-22 Hoffmann La Roche Verfahren und reagenzien zur identifizierung seltener foetaler zellen im maternen kreislauf
WO2002059316A2 (en) * 2001-01-23 2002-08-01 Lexicon Genetics Incorporated Human ion exchanger proteins and polynucleotides encoding the same
US20030144196A1 (en) * 2001-08-21 2003-07-31 Bowen Michael A. Activated T lymphocyte nucleic acid sequences and polypeptides encoded by same
US20030211522A1 (en) * 2002-01-18 2003-11-13 Landes Gregory M. Methods for fetal DNA detection and allele quantitation
WO2003071252A2 (en) * 2002-02-15 2003-08-28 Exact Sciences Corporation Methods for analysis of molecular events
US7217515B2 (en) * 2002-09-30 2007-05-15 Chi Mei Foundation Medical Center HURP gene as a molecular marker for bladder cancer
EP1413874A1 (de) 2002-10-16 2004-04-28 Streck Laboratories, Inc. Verfahren und Vorrichtung zum Sammeln und Konservieren von Zellen für die Analyse
AU2004209578A1 (en) * 2003-02-07 2004-08-19 Diagnocure Inc. Method to detect prostate cancer in a sample
EP1584923A3 (de) * 2004-04-07 2006-01-04 Roche Diagnostics GmbH Stabilisierung von Biomolekülen in Proben
WO2005111244A2 (en) * 2004-05-10 2005-11-24 Exact Sciences Corporation Methods for detecting a mutant nucleic acid
EP1784503A4 (de) 2004-07-23 2009-08-12 Pacific Edge Biotechnology Ltd Urinmarker zum nachweis von blasenkrebs
US7981607B2 (en) 2004-08-27 2011-07-19 Esoterix Genetic Laboratories LLC Method for detecting recombinant event
WO2006047483A2 (en) * 2004-10-22 2006-05-04 Redpath Integrated Pathology, Inc. Dynamic genomic deletion expansion and formulation of molecular marker panels for integrated molecular pathology diagnosis and characterization of tissue, cellular fluid, and pure fluid specimens
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
CA2491067A1 (en) 2004-12-24 2006-06-24 Stichting Katholieke Universiteit Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer
ITRM20050067A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici virali o di origine virale nelle urine.
AU2006214444B8 (en) * 2005-02-17 2012-04-05 Trovagene, Inc. Compositions and methods for detecting pathogen specific nucleic acids in urine
ITRM20050068A1 (it) 2005-02-17 2006-08-18 Istituto Naz Per Le Malattie I Metodo per la rivelazione di acidi nucleici di agenti patogeni batterici o di parassiti nelle urine.
US7914982B2 (en) 2005-02-17 2011-03-29 Trovagene, Inc. Methods for detecting pathogen specific nucleic acids in urine
US7449297B2 (en) * 2005-04-14 2008-11-11 Euclid Diagnostics Llc Methods of copying the methylation pattern of DNA during isothermal amplification and microarrays
US9777314B2 (en) * 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples
NZ545243A (en) 2006-02-10 2009-07-31 Pacific Edge Biotechnology Ltd Urine gene expression ratios for detection of cancer
ES2391212T3 (es) * 2006-12-07 2012-11-22 Novartis Ag Cribado genético prenatal no-invasivo
WO2008075790A2 (en) * 2006-12-20 2008-06-26 Olympus Corporation Method for detecting cancer with nucleic acids in blood
CN105400868B (zh) * 2007-08-22 2021-03-26 特罗瓦基因公司 使用miRNA检测体内细胞死亡情况的方法
US20100285469A1 (en) * 2007-10-10 2010-11-11 Philadelphia Health & Education d/b/a Drexel University College of Medicine Method of tumor screening
WO2009102632A2 (en) * 2008-02-12 2009-08-20 Biocept, Inc. Method for isolating cell free apoptotic or fetal nucleic acids
CA2717320A1 (en) * 2008-03-11 2009-09-17 Sequenom, Inc. Nucleic acid-based tests for prenatal gender determination
ES2595489T3 (es) * 2008-07-18 2016-12-30 Trovagene, Inc. Métodos para la detección de secuencias de ácidos nucleicos "ultracortos" basados en PCR
US8476013B2 (en) 2008-09-16 2013-07-02 Sequenom, Inc. Processes and compositions for methylation-based acid enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US8962247B2 (en) * 2008-09-16 2015-02-24 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non invasive prenatal diagnoses
US11634747B2 (en) 2009-01-21 2023-04-25 Streck Llc Preservation of fetal nucleic acids in maternal plasma
DE202010018569U1 (de) 2009-02-18 2017-09-26 Streck Inc. Konservierung zellfreier Nukleinsäuren
CA2780536C (en) * 2009-11-09 2018-01-02 Streck, Inc. Stabilization of rna in and extracting from intact cells within a blood sample
EP3088532B1 (de) 2009-12-22 2019-10-30 Sequenom, Inc. Verfahren und kits zur identifizierung von aneuploidie
WO2012149339A2 (en) 2011-04-29 2012-11-01 Sequenom, Inc. Quantification of a minority nucleic acid species
US9956281B2 (en) 2011-05-04 2018-05-01 Streck, Inc. Inactivated virus compositions and methods of preparing such compositions
DK2561103T3 (da) 2011-06-29 2014-10-20 Bgi Diagnosis Co Ltd Ikke-invasiv påvisning af føtal genetisk anomali
HK1206055A1 (en) 2012-03-02 2015-12-31 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US10504613B2 (en) 2012-12-20 2019-12-10 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
US9920361B2 (en) 2012-05-21 2018-03-20 Sequenom, Inc. Methods and compositions for analyzing nucleic acid
US20140093873A1 (en) 2012-07-13 2014-04-03 Sequenom, Inc. Processes and compositions for methylation-based enrichment of fetal nucleic acid from a maternal sample useful for non-invasive prenatal diagnoses
US9341628B2 (en) 2012-11-30 2016-05-17 Interpace Diagnostics Corporation Methods for measuring carcinoembryonic antigen
HK1216655A1 (zh) 2013-03-13 2016-11-25 Sequenom, Inc. 用於dna甲基化分析的引物
ES2938048T3 (es) 2013-07-24 2023-04-04 Streck Llc Composiciones y procedimientos para estabilizar las células tumorales circulantes
US11365447B2 (en) 2014-03-13 2022-06-21 Sequenom, Inc. Methods and processes for non-invasive assessment of genetic variations
EP3164503B1 (de) 2014-07-03 2024-08-28 Agilent Technologies, Inc. Verfahren zur nicht-invasiven detektion von transplantatgesundheit oder -abstossung
US11168351B2 (en) 2015-03-05 2021-11-09 Streck, Inc. Stabilization of nucleic acids in urine
US20170145475A1 (en) 2015-11-20 2017-05-25 Streck, Inc. Single spin process for blood plasma separation and plasma composition including preservative
EP4656715A3 (de) 2016-07-29 2026-02-25 Streck LLC Suspensionszusammensetzung zur kontrolle der hämatologischen analyse
EP3518974A4 (de) 2016-09-29 2020-05-27 Myriad Women's Health, Inc. Nichtinvasives pränatales screening unter verwendung von dynamischer iterativer tiefenoptimierung
CN115119829B (zh) 2017-10-19 2024-07-12 斯特雷克股份有限公司 用于胞外囊泡的溶血和凝血调节以及稳定化的组合物
WO2019236978A1 (en) 2018-06-07 2019-12-12 Biofire Diagnostics, Llc Rapid thermocycling methods
US11965217B2 (en) * 2020-07-21 2024-04-23 Delta Electronics, Inc. Method and kit for detecting Mycobacterium tuberculosis
AU2021400518A1 (en) * 2020-12-15 2023-07-06 Gateway Genomics, Llc Methods, compositions, and devices for the rapid determination of fetal sex

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5541331A (en) 1991-04-30 1996-07-30 Reilly Industries, Inc. Processes for producing α-pyridyl carbinols
ATE198358T1 (de) 1992-04-27 2001-01-15 Dartmouth College Detektion von gensequenzen in biologischen flüssigkeiten
US6020124A (en) * 1992-04-27 2000-02-01 Trustees Of Dartmouth College Detection of soluble gene sequences in biological fluids
US5541311A (en) 1992-12-07 1996-07-30 Third Wave Technologies, Inc. Nucleic acid encoding synthesis-deficient thermostable DNA polymerase
US5614402A (en) 1992-12-07 1997-03-25 Third Wave Technologies, Inc. 5' nucleases derived from thermostable DNA polymerase
WO1997006819A1 (en) * 1995-08-15 1997-02-27 Alteon Inc. Compositions and methods for elmination of advanced glycosylation endproducts (in vivo)
DE19540222A1 (de) * 1995-10-18 1997-04-24 Horst Dr Schlechte Verfahren und Vorrichtung zur Gewinnung Personen- und Krankheits-spezifischer Nucleinsäure-Sequenz-Daten
ATE414793T1 (de) 1996-01-24 2008-12-15 Third Wave Tech Inc Invasive spaltung von nukleinsäuren

Also Published As

Publication number Publication date
EP1634966A3 (de) 2006-06-21
WO1998054364A1 (en) 1998-12-03
AU7703998A (en) 1998-12-30
DK1634966T3 (da) 2011-02-07
ATE557103T1 (de) 2012-05-15
PT2216416E (pt) 2012-08-16
EP0920539A4 (de) 2004-06-09
EP0920539B9 (de) 2006-08-02
HK1088363A1 (en) 2006-11-03
ES2355631T3 (es) 2011-03-29
EP1634966A2 (de) 2006-03-15
ES2389055T3 (es) 2012-10-22
DK2216416T3 (da) 2012-08-27
ES2260837T3 (es) 2006-11-01
EP0920539A1 (de) 1999-06-09
CY1113124T1 (el) 2016-04-13
DE69833856T2 (de) 2006-11-23
EP1634966B1 (de) 2010-11-03
EP0920539B1 (de) 2006-03-15
US6251638B1 (en) 2001-06-26
EP2216416B1 (de) 2012-05-09
DE69841989D1 (de) 2010-12-16
DE69833856D1 (de) 2006-05-11
US6287820B1 (en) 2001-09-11
EP2216416A1 (de) 2010-08-11
DK0920539T3 (da) 2006-07-24
ATE320505T1 (de) 2006-04-15

Similar Documents

Publication Publication Date Title
ATE486958T1 (de) Verfahren zur bestimmung von nukleinsäuresequenzen in urin
DE69333289D1 (de) Verfahren zur bestimmung von säugetier nukleinsäuren aus stuhlproben und dafür benötigte reagenzien
DK1141728T3 (da) Påvisning af nyresygdom og behandling deraf
DE60000583D1 (de) Verfahren zur identifizierung und/oder quantifizierung einer zielverbindung
ATE515693T1 (de) Nachweis einer zielsubstanz in einer probe
DE69433816D1 (de) Die bestimmung von nukleinsäuremutationen durch analyse des sputum
DE60041355D1 (de) Verfahren zur detektion von erkrankungen
DE69939121D1 (de) Verfahren und materialien zum nachweis und zur messung von durch freie radikale verursachten schäden
CA2317816A1 (en) Peptide detection method
KR960007789A (ko) 단백질 c/단백질 s시스템의 장해를 검출하기 위한 방법
ATE333091T1 (de) Verfahren zur messung von blutersatzstoffen
RU2007148219A (ru) Способ обнаружения бактерий и тест-набор для их обнаружения
WO2001090408A3 (fr) Detection et caracterisation de l'activite de proteines impliquees dans la reparation de lesions de l'adn
DE60025336D1 (de) Verfahren und kit zur früherkennung von krebs
ATE209691T1 (de) Primer und sonden zur amplifizierung und zum nachweis von cmv nukleinsäure
DE60012723D1 (de) Verfahren zur bestimmung von disaccharidasen
DE59305225D1 (de) Verfahren zur Bestimmung von Thrombose verursachenden Lupus-anticoagulant-Antikörpern
DE60121547D1 (de) Electrochemisches verfahren zum nachweis von nukleinsäuren
ATE201769T1 (de) Verfahren zur kompetitiven bestimmung eines haptens
EP1580265A4 (de) Aus einem neuroblastom in stufe 4s isoliertenukleinsäuren
EP1136568A4 (de) Methode zum ermitteln der nukleinsäure
Martin et al. A comparative study of the citrate and lactate concentrations in stains from semen, vaginal secretion and mixtures of the two using isotachophoresis
ATE485515T1 (de) Verfahren zur diagnose einer person mit multipler sklerose
ATE269417T1 (de) Verfahren zur erkennung und messung von gespleisten nukleinsäuren
DE60237406D1 (de) Aus einem Neuroblastom isolierte Nukleinsäuren

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1634966

Country of ref document: EP