PT2204374E - Fosfonatos nucleosídeos e seus análogos para o tratamento de infecções com hpv - Google Patents

Fosfonatos nucleosídeos e seus análogos para o tratamento de infecções com hpv Download PDF

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Publication number
PT2204374E
PT2204374E PT10158740T PT10158740T PT2204374E PT 2204374 E PT2204374 E PT 2204374E PT 10158740 T PT10158740 T PT 10158740T PT 10158740 T PT10158740 T PT 10158740T PT 2204374 E PT2204374 E PT 2204374E
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PT
Portugal
Prior art keywords
quot
mmol
hpv
compound
compounds
Prior art date
Application number
PT10158740T
Other languages
English (en)
Portuguese (pt)
Inventor
Xiaqin Cheng
Gary P Cook
Manoj C Desai
Edward Doerffler
Gong-Xin He
Choung U Kim
William A Lee
John C Rohloff
Jianying Wang
Zheng-Yu Yang
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of PT2204374E publication Critical patent/PT2204374E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/44Amides thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/664Amides of phosphorus acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/20Antivirals for DNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PT10158740T 2003-12-30 2004-12-29 Fosfonatos nucleosídeos e seus análogos para o tratamento de infecções com hpv PT2204374E (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53374503P 2003-12-30 2003-12-30
US59098704P 2004-07-26 2004-07-26
US60659504P 2004-09-01 2004-09-01

Publications (1)

Publication Number Publication Date
PT2204374E true PT2204374E (pt) 2012-09-17

Family

ID=34753695

Family Applications (2)

Application Number Title Priority Date Filing Date
PT10158740T PT2204374E (pt) 2003-12-30 2004-12-29 Fosfonatos nucleosídeos e seus análogos para o tratamento de infecções com hpv
PT04815956T PT1716162E (pt) 2003-12-30 2004-12-29 Fosfonatos, monofosfonamidatos, bisfosfonamidatos para o tratamento de doenças virais

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT04815956T PT1716162E (pt) 2003-12-30 2004-12-29 Fosfonatos, monofosfonamidatos, bisfosfonamidatos para o tratamento de doenças virais

Country Status (28)

Country Link
US (5) US7553825B2 (sr)
EP (2) EP1716162B1 (sr)
JP (2) JP4949852B2 (sr)
KR (2) KR20120080240A (sr)
CN (2) CN1950383B (sr)
AP (1) AP2212A (sr)
AT (1) ATE478082T1 (sr)
AU (2) AU2004312546B2 (sr)
BR (1) BRPI0418251C1 (sr)
CA (1) CA2550222C (sr)
CY (2) CY1111050T1 (sr)
DE (1) DE602004028763D1 (sr)
DK (2) DK1716162T3 (sr)
EA (1) EA011304B1 (sr)
ES (2) ES2350983T3 (sr)
HK (2) HK1097276A1 (sr)
HR (3) HRP20060254A2 (sr)
IL (1) IL176407A (sr)
IS (1) IS2994B (sr)
NO (2) NO338001B1 (sr)
NZ (1) NZ548771A (sr)
PL (3) PL212403B1 (sr)
PT (2) PT2204374E (sr)
RS (2) RS52433B (sr)
SG (1) SG149075A1 (sr)
SI (2) SI2204374T1 (sr)
WO (1) WO2005066189A1 (sr)
ZA (1) ZA200606049B (sr)

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Publication number Publication date
JP2007517065A (ja) 2007-06-28
SI1716162T1 (sl) 2010-12-31
JP2011137029A (ja) 2011-07-14
EA200601263A1 (ru) 2006-12-29
US8268802B2 (en) 2012-09-18
DK1716162T3 (da) 2011-01-10
DK2204374T3 (da) 2012-09-10
CN101816664A (zh) 2010-09-01
US20090149400A1 (en) 2009-06-11
US8088754B2 (en) 2012-01-03
ES2389602T3 (es) 2012-10-29
NZ548771A (en) 2010-05-28
EA011304B1 (ru) 2009-02-27
CN1950383B (zh) 2010-06-09
PL1716162T3 (pl) 2011-02-28
IS8516A (is) 2006-06-21
US20060046981A1 (en) 2006-03-02
ES2350983T3 (es) 2011-01-28
HK1097276A1 (en) 2007-06-22
AU2004312546A1 (en) 2005-07-21
HRP20120699T1 (hr) 2012-09-30
PL380828A1 (pl) 2007-03-19
CY1113103T1 (el) 2016-04-13
RS51476B (sr) 2011-04-30
CA2550222C (en) 2013-05-28
CN1950383A (zh) 2007-04-18
JP4949852B2 (ja) 2012-06-13
BRPI0418251C1 (pt) 2021-05-25
PL2204374T3 (pl) 2012-11-30
PT1716162E (pt) 2010-11-24
US20050222090A1 (en) 2005-10-06
HRP20100626T1 (hr) 2011-03-31
AU2011200141A1 (en) 2011-02-03
HRP20060254A2 (en) 2006-10-31
EP1716162B1 (en) 2010-08-18
KR101214257B1 (ko) 2012-12-21
NO338040B1 (no) 2016-07-25
AU2011200141B2 (en) 2012-02-16
HK1146061A1 (en) 2011-05-13
US20090291922A1 (en) 2009-11-26
RS52433B (sr) 2013-02-28
SI2204374T1 (sl) 2012-09-28
NO20150615L (no) 2005-07-01
NO338001B1 (no) 2016-07-18
DE602004028763D1 (de) 2010-09-30
AU2004312546B2 (en) 2010-10-14
KR20120080240A (ko) 2012-07-16
KR20060129360A (ko) 2006-12-15
IS2994B (is) 2018-03-15
US7553825B2 (en) 2009-06-30
PL212403B1 (pl) 2012-09-28
CN101816664B (zh) 2012-04-18
AP2006003675A0 (en) 2006-08-31
AP2212A (en) 2011-03-01
IL176407A0 (en) 2006-10-05
BRPI0418251A (pt) 2007-04-17
EP1716162A1 (en) 2006-11-02
WO2005066189A1 (en) 2005-07-21
CA2550222A1 (en) 2005-07-21
BRPI0418251B8 (pt) 2019-10-08
BRPI0418251B1 (pt) 2019-09-24
ATE478082T1 (de) 2010-09-15
SG149075A1 (en) 2009-01-29
ZA200606049B (en) 2008-01-08
US20060030545A1 (en) 2006-02-09
CY1111050T1 (el) 2015-06-11
IL176407A (en) 2012-12-31
EP2204374A1 (en) 2010-07-07
NO20063479L (no) 2006-10-02
EP2204374B1 (en) 2012-06-13

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