HK1146061A1 - Nucleoside phosphonates and analogs thereof for the treatment of hpv- infections - Google Patents

Nucleoside phosphonates and analogs thereof for the treatment of hpv- infections

Info

Publication number
HK1146061A1
HK1146061A1 HK11100117.5A HK11100117A HK1146061A1 HK 1146061 A1 HK1146061 A1 HK 1146061A1 HK 11100117 A HK11100117 A HK 11100117A HK 1146061 A1 HK1146061 A1 HK 1146061A1
Authority
HK
Hong Kong
Prior art keywords
hpv
analogs
infections
treatment
nucleoside phosphonates
Prior art date
Application number
HK11100117.5A
Other languages
English (en)
Inventor
Xiaqin Cheng
Gary P Cook
Manoj C Desai
Edward Doerffler
Gong-Xin He
Choung U Kim
William A Lee
John C Rohloff
Jianying Wang
Zheng-Yu Yang
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of HK1146061A1 publication Critical patent/HK1146061A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids RP(=O)(OH)2; Thiophosphonic acids, i.e. RP(=X)(XH)2 (X = S, Se)
    • C07F9/44—Amides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/664—Amides of phosphorus acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
HK11100117.5A 2003-12-30 2011-01-06 Nucleoside phosphonates and analogs thereof for the treatment of hpv- infections HK1146061A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53374503P 2003-12-30 2003-12-30
US59098704P 2004-07-26 2004-07-26
US60659504P 2004-09-01 2004-09-01

Publications (1)

Publication Number Publication Date
HK1146061A1 true HK1146061A1 (en) 2011-05-13

Family

ID=34753695

Family Applications (2)

Application Number Title Priority Date Filing Date
HK07104599.0A HK1097276A1 (en) 2003-12-30 2007-04-30 Phosphonates, monophosphonamidates, bisphosphonamidates for the treatment of viral diseases
HK11100117.5A HK1146061A1 (en) 2003-12-30 2011-01-06 Nucleoside phosphonates and analogs thereof for the treatment of hpv- infections

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK07104599.0A HK1097276A1 (en) 2003-12-30 2007-04-30 Phosphonates, monophosphonamidates, bisphosphonamidates for the treatment of viral diseases

Country Status (28)

Country Link
US (5) US7553825B2 (xx)
EP (2) EP2204374B1 (xx)
JP (2) JP4949852B2 (xx)
KR (2) KR20120080240A (xx)
CN (2) CN1950383B (xx)
AP (1) AP2212A (xx)
AT (1) ATE478082T1 (xx)
AU (2) AU2004312546B2 (xx)
BR (1) BRPI0418251C1 (xx)
CA (1) CA2550222C (xx)
CY (2) CY1111050T1 (xx)
DE (1) DE602004028763D1 (xx)
DK (2) DK2204374T3 (xx)
EA (1) EA011304B1 (xx)
ES (2) ES2389602T3 (xx)
HK (2) HK1097276A1 (xx)
HR (3) HRP20060254A2 (xx)
IL (1) IL176407A (xx)
IS (1) IS2994B (xx)
NO (2) NO338001B1 (xx)
NZ (1) NZ548771A (xx)
PL (3) PL212403B1 (xx)
PT (2) PT1716162E (xx)
RS (2) RS51476B (xx)
SG (1) SG149075A1 (xx)
SI (2) SI2204374T1 (xx)
WO (1) WO2005066189A1 (xx)
ZA (1) ZA200606049B (xx)

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Also Published As

Publication number Publication date
NO20150615L (no) 2005-07-01
RS52433B (en) 2013-02-28
US20060030545A1 (en) 2006-02-09
KR101214257B1 (ko) 2012-12-21
US20090149400A1 (en) 2009-06-11
CA2550222C (en) 2013-05-28
HK1097276A1 (en) 2007-06-22
PT1716162E (pt) 2010-11-24
AP2212A (en) 2011-03-01
US8268802B2 (en) 2012-09-18
CN101816664B (zh) 2012-04-18
BRPI0418251B8 (pt) 2019-10-08
AU2004312546A1 (en) 2005-07-21
NO338040B1 (no) 2016-07-25
EP1716162B1 (en) 2010-08-18
JP2011137029A (ja) 2011-07-14
DK1716162T3 (da) 2011-01-10
CN1950383B (zh) 2010-06-09
SI2204374T1 (sl) 2012-09-28
PL380828A1 (pl) 2007-03-19
SG149075A1 (en) 2009-01-29
DK2204374T3 (da) 2012-09-10
BRPI0418251C1 (pt) 2021-05-25
KR20120080240A (ko) 2012-07-16
US7553825B2 (en) 2009-06-30
JP2007517065A (ja) 2007-06-28
EP2204374A1 (en) 2010-07-07
EP1716162A1 (en) 2006-11-02
HRP20100626T1 (hr) 2011-03-31
US8088754B2 (en) 2012-01-03
KR20060129360A (ko) 2006-12-15
ATE478082T1 (de) 2010-09-15
PL2204374T3 (pl) 2012-11-30
CY1113103T1 (el) 2016-04-13
DE602004028763D1 (de) 2010-09-30
AP2006003675A0 (en) 2006-08-31
CN1950383A (zh) 2007-04-18
IL176407A (en) 2012-12-31
CN101816664A (zh) 2010-09-01
IL176407A0 (en) 2006-10-05
IS8516A (is) 2006-06-21
US20090291922A1 (en) 2009-11-26
PL1716162T3 (pl) 2011-02-28
AU2011200141B2 (en) 2012-02-16
NO338001B1 (no) 2016-07-18
CA2550222A1 (en) 2005-07-21
IS2994B (is) 2018-03-15
HRP20120699T1 (hr) 2012-09-30
ZA200606049B (en) 2008-01-08
AU2011200141A1 (en) 2011-02-03
AU2004312546B2 (en) 2010-10-14
EA011304B1 (ru) 2009-02-27
PT2204374E (pt) 2012-09-17
US20060046981A1 (en) 2006-03-02
SI1716162T1 (sl) 2010-12-31
HRP20060254A2 (en) 2006-10-31
RS51476B (en) 2011-04-30
US20050222090A1 (en) 2005-10-06
NO20063479L (no) 2006-10-02
WO2005066189A1 (en) 2005-07-21
EP2204374B1 (en) 2012-06-13
JP4949852B2 (ja) 2012-06-13
ES2389602T3 (es) 2012-10-29
BRPI0418251B1 (pt) 2019-09-24
BRPI0418251A (pt) 2007-04-17
NZ548771A (en) 2010-05-28
PL212403B1 (pl) 2012-09-28
CY1111050T1 (el) 2015-06-11
EA200601263A1 (ru) 2006-12-29
ES2350983T3 (es) 2011-01-28

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