PT2001862E - Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico - Google Patents

Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico Download PDF

Info

Publication number
PT2001862E
PT2001862E PT07735261T PT07735261T PT2001862E PT 2001862 E PT2001862 E PT 2001862E PT 07735261 T PT07735261 T PT 07735261T PT 07735261 T PT07735261 T PT 07735261T PT 2001862 E PT2001862 E PT 2001862E
Authority
PT
Portugal
Prior art keywords
polymorphs
piperidinyl
cyclopropyl
dihydro
oxo
Prior art date
Application number
PT07735261T
Other languages
English (en)
Inventor
Nancy Lee Redman-Furey
Jane Ellen Godlewski
Michael Lloyd Dicks
Original Assignee
Warner Chilcott Co Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38441484&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2001862(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Chilcott Co Llc filed Critical Warner Chilcott Co Llc
Publication of PT2001862E publication Critical patent/PT2001862E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
PT07735261T 2006-03-28 2007-03-26 Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico PT2001862E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78648306P 2006-03-28 2006-03-28

Publications (1)

Publication Number Publication Date
PT2001862E true PT2001862E (pt) 2011-07-20

Family

ID=38441484

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07735261T PT2001862E (pt) 2006-03-28 2007-03-26 Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico

Country Status (27)

Country Link
US (1) US8039485B2 (pt)
EP (1) EP2001862B1 (pt)
JP (1) JP5097967B2 (pt)
KR (1) KR101102288B1 (pt)
AR (2) AR060189A1 (pt)
AT (1) ATE507219T1 (pt)
AU (1) AU2007230630B2 (pt)
BR (1) BRPI0709772B8 (pt)
CA (1) CA2647346C (pt)
CY (1) CY1111683T1 (pt)
DE (1) DE602007014191D1 (pt)
DK (1) DK2001862T3 (pt)
ES (1) ES2366150T3 (pt)
HR (1) HRP20110558T1 (pt)
IL (1) IL193990A (pt)
MA (1) MA30554B1 (pt)
MX (1) MX2008012328A (pt)
MY (1) MY148393A (pt)
NZ (1) NZ570494A (pt)
PE (1) PE20080175A1 (pt)
PL (1) PL2001862T3 (pt)
PT (1) PT2001862E (pt)
SI (1) SI2001862T1 (pt)
SM (1) SMP200800058B (pt)
TW (1) TWI364419B (pt)
WO (1) WO2007110834A2 (pt)
ZA (1) ZA200807158B (pt)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0709220A2 (pt) * 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona
US8658183B2 (en) * 2007-08-09 2014-02-25 Taigen Biotechnology Company, Ltd. Antimicrobial parenteral formulation
CA2728328C (en) * 2008-07-01 2015-02-24 Taigen Biotechnology Co., Ltd. Treatment of antibiotic-resistant bacteria infection
CN101618039B (zh) * 2008-07-02 2012-04-11 太景生物科技股份有限公司 肺炎的治疗药物
US8553466B2 (en) 2010-03-04 2013-10-08 Samsung Electronics Co., Ltd. Non-volatile memory device, erasing method thereof, and memory system including the same
CZ304984B6 (cs) 2012-10-12 2015-03-11 Zentiva, K.S. Zlepšený způsob výroby a nové intermediáty syntézy elvitegraviru
CZ304983B6 (cs) * 2012-10-12 2015-03-11 Zentiva, K.S. Způsob výroby a nové intermediáty syntézy elvitegraviru
CN103145615B (zh) * 2013-03-20 2015-07-29 浙江医药股份有限公司 一种奈诺沙星螯合物的后处理方法

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017622A (en) * 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
JPS5186476A (en) 1975-01-17 1976-07-29 Yoshitomi Pharmaceutical Shinkina kinoronkarubonsanjudotaino seiho
JPS5845426B2 (ja) * 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
JPS604820B2 (ja) * 1979-02-26 1985-02-06 大塚製薬株式会社 キノリンカルボン酸誘導体
JPS5649382A (en) * 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
IE55898B1 (en) 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
US4665079A (en) * 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
US5281612A (en) 1982-09-09 1994-01-25 Warner-Lambert Company Naphthyridine antibacterial agents
DE3248506A1 (de) * 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4994599A (en) * 1987-11-20 1991-02-19 Abbott Laboratories Intermediates for producing quinolone-3-carboxylic acids
JPS60221484A (ja) * 1984-04-17 1985-11-06 Fuji Photo Film Co Ltd 放射線像変換方法およびその方法に用いられる放射線像変換パネル
DE3420798A1 (de) * 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
US4822801A (en) * 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
US4771054A (en) * 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
JPS61225181A (ja) 1986-02-04 1986-10-06 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法
JPS61205258A (ja) 1985-03-08 1986-09-11 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法
HUT40639A (en) 1985-03-08 1987-01-28 Kyorin Seiyaku Kk Process for producing quinolon-carboxylic acid derivative and pharmaceutical composition containing them
EP0207420B1 (en) * 1985-06-26 1992-05-06 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives
JPS6236377A (ja) 1985-07-03 1987-02-17 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
JPH089597B2 (ja) 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
DE3705621C2 (de) * 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62205060A (ja) 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd ８位置換キノロンカルボン酸誘導体
JPS62215572A (ja) 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
JPH0717608B2 (ja) 1986-04-25 1995-03-01 杏林製薬株式会社 ６−アルコキシキノロンカルボン酸誘導体
DE3704907A1 (de) * 1987-02-17 1988-08-25 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden
US4780468A (en) * 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
US4997946A (en) * 1987-08-18 1991-03-05 Eastman Kodak Company Process for the iodination of hydroxyaromatic and aminoaromatic compounds
JPH0676400B2 (ja) 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
US4921857A (en) 1987-09-18 1990-05-01 Merck & Co., Inc. 4-Oxo-4h-quinolizine-3-carboxylic acids and derivatives thereof
US4920120A (en) * 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
EP0342675B1 (en) 1988-05-19 1995-01-25 Chugai Seiyaku Kabushiki Kaisha Novel quinolonecarboxylic acid derivatives
JP2844079B2 (ja) * 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
DE3906365A1 (de) * 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
FI95130C (fi) * 1988-07-20 1995-12-27 Sankyo Co Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
US5328908A (en) * 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
EP0997466A1 (en) * 1988-10-24 2000-05-03 PROCTER & GAMBLE PHARMACEUTICALS, INC. Novel antimicrobial lactam-quinolones
CA2001203C (en) * 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Novel antimicrobial dithiocarbamoyl quinolones
IE66202B1 (en) 1989-08-16 1995-12-13 Pfizer Azabicyclo quinolone carboxylic acids
US5164402A (en) * 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
CA2036516A1 (en) 1990-02-19 1991-08-20 Yoshikazu Asahina Optically active 8-methoxyouinolonecarboxylic acid derivatives, their preparative processes and their intermediates
US5116834A (en) 1990-04-12 1992-05-26 Warner-Lambert Company Quinolinecarboxylic acid antibacterial agents
US5599816A (en) * 1990-05-02 1997-02-04 Abbott Laboratories Quinolizinone type compounds
US5580872A (en) * 1990-05-02 1996-12-03 Abbott Laboratories Quinolizinone type compounds
IE911472A1 (en) 1990-05-02 1991-11-06 Abbott Lab Quinolizinone type compounds
JPH0778065B2 (ja) 1990-07-06 1995-08-23 杏林製薬株式会社 （６，７―置換―８―アルコキシ―１―シクロプロピル―１，４―ジヒドロ―４―オキソ―３―キノリンカルボン酸―ｏ▲上３▼，ｏ▲上４▼）ビス（アシルオキシ―ｏ）ホウ素化合物及びその塩並びにその製造方法
US5364861A (en) * 1990-11-30 1994-11-15 Warner-Lambert Company Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents
US5258528A (en) * 1990-11-30 1993-11-02 Warner-Lambert Company Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group
US5072001A (en) * 1990-11-30 1991-12-10 Warner-Lambert Company Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates
DE4120646A1 (de) * 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE4123918A1 (de) 1991-07-19 1993-01-21 Bayer Ag 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren
WO1993013091A1 (en) * 1991-12-27 1993-07-08 Wakunaga Seiyaku Kabushiki Kaisha Novel quinolone derivative or salt thereof and antibacterial containing the same
EP0550016A1 (en) 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same
NO304832B1 (no) 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
DE4230804A1 (de) * 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4234078A1 (de) * 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
KR0148277B1 (ko) * 1993-01-18 1998-11-02 채영복 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
DE4301246A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
DE4301245A1 (de) * 1993-01-19 1994-07-21 Bayer Ag Fluor-trifluormethylbenzoesäure-Derivate
CA2152828A1 (en) 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
TW252107B (pt) * 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
BR9407806A (pt) 1993-10-14 1997-08-19 Abbott Lab Composto processo de tratamento de uma infecção bacteriana em um paciente humano ou veterinário e intermediário sintético
CN1070191C (zh) 1994-08-12 2001-08-29 富山化学工业株式会社 新的喹诺酮－或萘酮－羧酸衍生物或其盐
JP3745433B2 (ja) 1995-02-02 2006-02-15 第一製薬株式会社 複素環式化合物
CA2212226A1 (en) 1995-02-02 1995-08-10 Katsumi Chiba Bicyclic amino group-substituted pyridonecarboxylic acid derivatives, esters thereof and salts thereof, and bicyclic amines useful as intermediates thereof
US5849757A (en) 1995-02-02 1998-12-15 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials
DE19512484A1 (de) 1995-04-04 1996-10-17 Bayer Ag Kohlenhydratmodifizierte Cytostatika
AU6153096A (en) 1995-06-06 1996-12-24 Abbott Laboratories Quinolizinone type compounds
IT1279532B1 (it) 1995-07-24 1997-12-16 Mediolanum Farmaceutici Spa Derivati chinolonici non fluorurati e loro impiego come agenti antibatterici
DK0911328T3 (da) 1995-11-22 2006-06-06 Daiichi Seiyaku Co Substituerede aminocycloalkylpyrrolidinderivater
PT947513E (pt) 1996-10-25 2004-09-30 Daiichi Seiyaku Co Derivados de amina triciclicos
US6274592B1 (en) 1997-02-04 2001-08-14 Senju Pharmaceutical Co., Ltd. Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
ID24434A (id) 1997-05-21 2000-07-20 Daiichi Seiyaku Co Derivat aminosikloalkilpirolidin tersubstitusi cis-tersubstitusi
MY119816A (en) 1997-05-30 2005-07-29 Daiichi Seiyaku Co Substituted cyclobutylamine derivatives
KR100241673B1 (ko) 1997-08-09 2000-03-02 김충섭 퀴놀리진 카르복실산 유도체
HUP0100051A3 (en) * 1997-09-15 2002-08-28 Procter & Gamble Antimicrobial quinolones, their compositions and uses
US6387928B1 (en) * 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
BR0017010A (pt) 2000-01-24 2002-11-05 Warner Lambert Co Agentes antibacterianos 3-aminoquinazolin-2,4-diona
JP2004515548A (ja) * 2000-12-14 2004-05-27 ザ プロクター アンド ギャンブル カンパニー 抗微生物キノロン
JP4250353B2 (ja) * 2001-06-22 2009-04-08 エドワーズ株式会社 真空ポンプ
US6900224B2 (en) * 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
US6803469B2 (en) * 2002-08-05 2004-10-12 The Procter & Gamble Company Process for preparing quinolone antibiotic intermediates
US7179805B2 (en) * 2003-09-22 2007-02-20 Janssen Pharmaceutica N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
US7732612B2 (en) * 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
EP1999106B1 (en) * 2006-03-28 2012-06-27 TaiGen Biotechnology Co., Ltd. A hydride reduction process for preparing quinolone intermediates
BRPI0709220A2 (pt) * 2006-03-28 2011-07-12 Procter & Gamble processo de acoplamento para preparo de intermediários de quinolona

Also Published As

Publication number Publication date
RU2008134544A (ru) 2010-05-10
CA2647346C (en) 2011-07-19
WO2007110834A2 (en) 2007-10-04
SI2001862T1 (sl) 2011-10-28
BRPI0709772A2 (pt) 2011-07-26
SMP200800058B (it) 2009-09-07
KR101102288B1 (ko) 2012-01-03
AU2007230630B2 (en) 2012-12-20
BRPI0709772B1 (pt) 2019-10-15
AR060377A1 (es) 2008-06-11
KR20090004887A (ko) 2009-01-12
WO2007110834A3 (en) 2007-12-06
RU2417222C2 (ru) 2011-04-27
DK2001862T3 (da) 2011-08-08
MA30554B1 (fr) 2009-07-01
CA2647346A1 (en) 2007-10-04
JP5097967B2 (ja) 2012-12-12
DE602007014191D1 (en) 2011-06-09
EP2001862B1 (en) 2011-04-27
SMAP200800058A (it) 2008-10-29
CY1111683T1 (el) 2015-10-07
HRP20110558T1 (hr) 2011-09-30
ATE507219T1 (de) 2011-05-15
MX2008012328A (es) 2008-10-09
NZ570494A (en) 2011-09-30
BRPI0709772B8 (pt) 2021-05-25
JP2009531417A (ja) 2009-09-03
TWI364419B (en) 2012-05-21
US8039485B2 (en) 2011-10-18
IL193990A (en) 2014-12-31
AU2007230630A1 (en) 2007-10-04
ES2366150T3 (es) 2011-10-17
PL2001862T3 (pl) 2011-09-30
MY148393A (en) 2013-04-15
ZA200807158B (en) 2009-09-30
PE20080175A1 (es) 2008-03-14
TW200808759A (en) 2008-02-16
AR060189A1 (es) 2008-05-28
EP2001862A2 (en) 2008-12-17
US20070232650A1 (en) 2007-10-04

Similar Documents

Publication Publication Date Title
PL2001862T3 (pl) Jabłczany oraz odmiany polimorficzne kwasu (3S,5S)-7-[3-amino-5-metylo-piperydynylo]-1-cyklopropylo-1,4-dihydro-8-metoksy-4-okso-3-chinolinokarboksylowego
SI2178840T1 (sl) Derivativi azabifenilaminobenzojske kisline kot dhodh inhibitorji
SG10201500639TA (en) Processes for the preparation of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid and salts thereof
IL247136B (en) Compounds for reducing uric acid and their uses
GB0604899D0 (en) Derivatives of 18-glycyrrhetinic acid
HK1169379A1 (en) Salts of 3-pentylphenylacetic acid and pharmaceutical uses thereof 3-
HRP20181437T1 (hr) Postupak proizvodnje (3s,3s') 4,4' disulfanedilbis (3-aminobutan-1-sulfonske kiseline)
EP2394645A4 (en) MEDICAL USE OF 5-BENZYLAMINOSALICYLIC ACID DERIVATIVES OR SALTS THEREOF
IL248077B (en) Formulations, salts and polymers of transnorsertraline and their uses
ZA201105542B (en) Cefdinir acid double salt and its preparation
AU2006259123A8 (en) Spiro-benzimidazoles as inhibitors of gastric acid secretion
ZA201303695B (en) Pharmaceutical composition comprising citrate and bicarbonate salts,and use thereof for treating cystinuria
EP2488020A4 (en) 3-SUBSTITUTED COMPOUNDS FOR REDUCING URIC ACID
IL200456A0 (en) Enantiomers of amino-phenyl-acetic acid octadec-9-(z)enyl ester, their salts and their uses
ZA201405266B (en) Combination of (3s, 3s') 4,4'-disulfanediylbis(3-aminobutane 1-sulfonic acid) and a second antihypertensive agent
ZA201000383B (en) Azabiphenylaminobenzoic acid derivatives as DHODH inhibitors