PT2001862E - Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico - Google Patents

Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico Download PDF

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Publication number
PT2001862E
PT2001862E PT07735261T PT07735261T PT2001862E PT 2001862 E PT2001862 E PT 2001862E PT 07735261 T PT07735261 T PT 07735261T PT 07735261 T PT07735261 T PT 07735261T PT 2001862 E PT2001862 E PT 2001862E
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PT
Portugal
Prior art keywords
polymorphs
piperidinyl
cyclopropyl
dihydro
oxo
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Application number
PT07735261T
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English (en)
Inventor
Nancy Lee Redman-Furey
Jane Ellen Godlewski
Michael Lloyd Dicks
Original Assignee
Warner Chilcott Co Llc
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Application filed by Warner Chilcott Co Llc filed Critical Warner Chilcott Co Llc
Publication of PT2001862E publication Critical patent/PT2001862E/pt

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
PT07735261T 2006-03-28 2007-03-26 Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico PT2001862E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78648306P 2006-03-28 2006-03-28

Publications (1)

Publication Number Publication Date
PT2001862E true PT2001862E (pt) 2011-07-20

Family

ID=38441484

Family Applications (1)

Application Number Title Priority Date Filing Date
PT07735261T PT2001862E (pt) 2006-03-28 2007-03-26 Sais de malato e polimorfos do ácido (3s,5s)-7-[3- amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro- 8-metoxi-4-oxo-3-quinolinocarboxílico

Country Status (27)

Country Link
US (1) US8039485B2 (pt)
EP (1) EP2001862B1 (pt)
JP (1) JP5097967B2 (pt)
KR (1) KR101102288B1 (pt)
AR (2) AR060189A1 (pt)
AT (1) ATE507219T1 (pt)
AU (1) AU2007230630B2 (pt)
BR (1) BRPI0709772B8 (pt)
CA (1) CA2647346C (pt)
CY (1) CY1111683T1 (pt)
DE (1) DE602007014191D1 (pt)
DK (1) DK2001862T3 (pt)
ES (1) ES2366150T3 (pt)
HR (1) HRP20110558T1 (pt)
IL (1) IL193990A (pt)
MA (1) MA30554B1 (pt)
MX (1) MX2008012328A (pt)
MY (1) MY148393A (pt)
NZ (1) NZ570494A (pt)
PE (1) PE20080175A1 (pt)
PL (1) PL2001862T3 (pt)
PT (1) PT2001862E (pt)
SI (1) SI2001862T1 (pt)
SM (1) SMP200800058B (pt)
TW (1) TWI364419B (pt)
WO (1) WO2007110834A2 (pt)
ZA (1) ZA200807158B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007110835A2 (en) * 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
US8658183B2 (en) * 2007-08-09 2014-02-25 Taigen Biotechnology Company, Ltd. Antimicrobial parenteral formulation
EP2303271B1 (en) * 2008-07-01 2018-11-07 Taigen Biotechnology Co., Ltd. Treatment of antibiotic-resistant bacteria infection
CN101618039B (zh) * 2008-07-02 2012-04-11 太景生物科技股份有限公司 肺炎的治疗药物
US8553466B2 (en) 2010-03-04 2013-10-08 Samsung Electronics Co., Ltd. Non-volatile memory device, erasing method thereof, and memory system including the same
CZ304984B6 (cs) 2012-10-12 2015-03-11 Zentiva, K.S. Zlepšený způsob výroby a nové intermediáty syntézy elvitegraviru
CZ304983B6 (cs) * 2012-10-12 2015-03-11 Zentiva, K.S. Způsob výroby a nové intermediáty syntézy elvitegraviru
CN103145615B (zh) * 2013-03-20 2015-07-29 浙江医药股份有限公司 一种奈诺沙星螯合物的后处理方法
CN114437026A (zh) * 2021-10-26 2022-05-06 浙江医药股份有限公司新昌制药厂 一种低组合物杂质的苹果酸奈诺沙星原料药及其制备方法

Family Cites Families (88)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4017622A (en) 1972-12-18 1977-04-12 Dainippon Pharmaceutical Co., Ltd. Piperazine derivatives
JPS5186476A (en) 1975-01-17 1976-07-29 Yoshitomi Pharmaceutical Shinkina kinoronkarubonsanjudotaino seiho
JPS5845426B2 (ja) 1978-09-29 1983-10-08 杏林製薬株式会社 置換キノリンカルボン酸誘導体
JPS604820B2 (ja) 1979-02-26 1985-02-06 大塚製薬株式会社 キノリンカルボン酸誘導体
JPS5649382A (en) 1979-09-28 1981-05-02 Dainippon Pharmaceut Co Ltd 6-fluoro-7-cyclic amino-1,8-naphthylidine derivative and its salt
US4665079A (en) 1984-02-17 1987-05-12 Warner-Lambert Company Antibacterial agents
IE55898B1 (en) 1982-09-09 1991-02-14 Warner Lambert Co Antibacterial agents
US5281612A (en) 1982-09-09 1994-01-25 Warner-Lambert Company Naphthyridine antibacterial agents
DE3248506A1 (de) 1982-12-29 1984-07-05 Bayer Ag, 5090 Leverkusen 1-cyclopropyl-6-fluor-1,4-dihydro-4-oxo-7(alkyl-1-piperazinyl)-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
US4994599A (en) 1987-11-20 1991-02-19 Abbott Laboratories Intermediates for producing quinolone-3-carboxylic acids
JPS60221484A (ja) 1984-04-17 1985-11-06 Fuji Photo Film Co Ltd 放射線像変換方法およびその方法に用いられる放射線像変換パネル
DE3420798A1 (de) 1984-06-04 1985-12-05 Bayer Ag, 5090 Leverkusen 7-(3-aryl-l-piperazinyl)- sowie 7-(3-cyclohexyl-l-piperazinyl)-3-chinoloncarbonsaeuren
US4822801A (en) 1984-07-20 1989-04-18 Warner-Lambert Company 4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivative as antibacterial agents
US4771054A (en) 1985-01-23 1988-09-13 Warner-Lambert Company Antibacterial agents
JPS61205258A (ja) 1985-03-08 1986-09-11 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法
HUT40639A (en) 1985-03-08 1987-01-28 Kyorin Seiyaku Kk Process for producing quinolon-carboxylic acid derivative and pharmaceutical composition containing them
JPS61225181A (ja) 1986-02-04 1986-10-06 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体及びその製造方法
IL79189A (en) 1985-06-26 1990-07-12 Daiichi Seiyaku Co Quinoline and/or naphthyridine-4-oxo-3-carboxylic acid derivatives,process for their preparation and pharmaceutical compositions comprising them
JPS6236377A (ja) 1985-07-03 1987-02-17 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
JPH089597B2 (ja) 1986-01-21 1996-01-31 杏林製薬株式会社 選択毒性に優れた8‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法
DE3705621C2 (de) 1986-02-25 1997-01-09 Otsuka Pharma Co Ltd Heterocyclisch substituierte Chinoloncarbonsäurederivate
JPS62205060A (ja) 1986-03-04 1987-09-09 Kyorin Pharmaceut Co Ltd 8位置換キノロンカルボン酸誘導体
JPS62215572A (ja) 1986-03-17 1987-09-22 Kyorin Pharmaceut Co Ltd キノロンカルボン酸誘導体
JPH0717608B2 (ja) 1986-04-25 1995-03-01 杏林製薬株式会社 6−アルコキシキノロンカルボン酸誘導体
DE3704907A1 (de) 1987-02-17 1988-08-25 Bayer Ag Topisch anwendbare zubereitungen von gyrase-inhibitoren in kombination mit kortikosteroiden
US4780468A (en) 1987-08-07 1988-10-25 Warner-Lambert Company 8-trifluoromethyl quinolones as antibacterial agents
US4997946A (en) 1987-08-18 1991-03-05 Eastman Kodak Company Process for the iodination of hydroxyaromatic and aminoaromatic compounds
JPH0676400B2 (ja) 1987-08-25 1994-09-28 大日本製薬株式会社 新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
US4921857A (en) 1987-09-18 1990-05-01 Merck & Co., Inc. 4-Oxo-4h-quinolizine-3-carboxylic acids and derivatives thereof
US4920120A (en) 1988-01-25 1990-04-24 Warner-Lambert Company Antibacterial agents
ES2070142T3 (es) 1988-05-19 1995-06-01 Chugai Pharmaceutical Co Ltd Nuevos derivados del acido quinolonacarboxilico.
JP2844079B2 (ja) 1988-05-23 1999-01-06 塩野義製薬株式会社 ピリドンカルボン酸系抗菌剤
DE3906365A1 (de) 1988-07-15 1990-01-18 Bayer Ag 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe
FI95130C (fi) 1988-07-20 1995-12-27 Sankyo Co Menetelmä lääkeaineena käyttökelpoisten 4-oksokinoliini-3-karboksyylihapon johdannaisten valmistamiseksi
US5286723A (en) 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
EP0366189A3 (en) 1988-10-24 1992-01-02 Norwich Eaton Pharmaceuticals, Inc. Novel antimicrobial lactam-quinolones
CA2001203C (en) 1988-10-24 2001-02-13 Thomas P. Demuth, Jr. Novel antimicrobial dithiocarbamoyl quinolones
US5328908A (en) 1988-10-24 1994-07-12 Procter & Gamble Pharmaceuticals, Inc. Antimicrobial quinolone thioureas
US5164402A (en) 1989-08-16 1992-11-17 Pfizer Inc Azabicyclo quinolone and naphthyridinone carboxylic acids
RU2049777C1 (ru) 1989-08-16 1995-12-10 Пфайзер Инк. Азабицикло-хинолон-карбоновые кислоты или их фармацевтически приемлемые кислотно-аддитивные соли и промежуточные продукты для их получения
CN1054980A (zh) 1990-02-19 1991-10-02 杏林制药株式会社 具有旋光活性的8-甲氧基喹诺酮羧酸衍生物,它们的制备方法以及它们的中间体
US5116834A (en) 1990-04-12 1992-05-26 Warner-Lambert Company Quinolinecarboxylic acid antibacterial agents
IE911472A1 (en) 1990-05-02 1991-11-06 Abbott Lab Quinolizinone type compounds
US5599816A (en) 1990-05-02 1997-02-04 Abbott Laboratories Quinolizinone type compounds
US5580872A (en) 1990-05-02 1996-12-03 Abbott Laboratories Quinolizinone type compounds
JPH0778065B2 (ja) 1990-07-06 1995-08-23 杏林製薬株式会社 (6,7―置換―8―アルコキシ―1―シクロプロピル―1,4―ジヒドロ―4―オキソ―3―キノリンカルボン酸―o▲上3▼,o▲上4▼)ビス(アシルオキシ―o)ホウ素化合物及びその塩並びにその製造方法
US5258528A (en) 1990-11-30 1993-11-02 Warner-Lambert Company Individual stereoisomers of pyrrolidine methanamines substituted on the ring nitrogen by a 1-phenylethyl group
US5364861A (en) 1990-11-30 1994-11-15 Warner-Lambert Company Optical isomers of 7-[3-(1,1-dialkylmethyl-1-amino-1-pyrrolidinyl]-quinolones and naphthyridones as antibacterial agents
US5072001A (en) 1990-11-30 1991-12-10 Warner-Lambert Company Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates
DE4120646A1 (de) 1991-06-22 1992-12-24 Bayer Ag 7-isoindolinyl-chinolon- und naphthyridoncarbonsaeure-derivate
DE4123918A1 (de) 1991-07-19 1993-01-21 Bayer Ag 8-vinyl- und 8-ethinyl-chinoloncarbonsaeuren
US5412098A (en) 1991-12-27 1995-05-02 Wakunaga Seiyaku Kabushiki Kaisha Quinolone derivative or salt thereof and antibacterial containing the same
EP0550016A1 (en) 1991-12-31 1993-07-07 Korea Research Institute Of Chemical Technology Novel quinolone carboxylic acid derivatives and processes for preparing same
NO304832B1 (no) 1992-05-27 1999-02-22 Ube Industries Aminokinolonderivater samt middel mot HIV
DE4230804A1 (de) 1992-09-15 1994-03-17 Bayer Ag 7-Isoindolinyl-chinolon- und -naphthyridon-Derivate
DE4234078A1 (de) 1992-10-09 1994-04-14 Bayer Ag Chinoloncarbonsäuren
KR0148277B1 (ko) 1993-01-18 1998-11-02 채영복 신규한 플루오르퀴놀론계 유도체 및 그의 제조방법
DE4301246A1 (de) 1993-01-19 1994-07-21 Bayer Ag Chinolon- und Naphthyridoncarbonsäurederivate
DE4301245A1 (de) 1993-01-19 1994-07-21 Bayer Ag Fluor-trifluormethylbenzoesäure-Derivate
CA2152828A1 (en) 1993-03-16 1994-07-07 Shin-Ichi Uesato 8-methoxy-quinolonecarboxylic acid derivatives
TW252107B (pt) 1993-08-27 1995-07-21 Hokuriku Pharmacetical Co Ltd
CN1053188C (zh) 1993-10-14 2000-06-07 艾博特公司 喹嗪酮类化合物
CN1070191C (zh) 1994-08-12 2001-08-29 富山化学工业株式会社 新的喹诺酮-或萘酮-羧酸衍生物或其盐
JP3745433B2 (ja) 1995-02-02 2006-02-15 第一製薬株式会社 複素環式化合物
CA2212226A1 (en) 1995-02-02 1995-08-10 Katsumi Chiba Bicyclic amino group-substituted pyridonecarboxylic acid derivatives, esters thereof and salts thereof, and bicyclic amines useful as intermediates thereof
US5849757A (en) 1995-02-02 1998-12-15 Daiichi Pharmaceutical Co., Ltd. Pyridonecarboxylic acid derivatives substituted by a bicyclic amino group as antibacterials
DE19512484A1 (de) 1995-04-04 1996-10-17 Bayer Ag Kohlenhydratmodifizierte Cytostatika
AU6153096A (en) 1995-06-06 1996-12-24 Abbott Laboratories Quinolizinone type compounds
IT1279532B1 (it) 1995-07-24 1997-12-16 Mediolanum Farmaceutici Spa Derivati chinolonici non fluorurati e loro impiego come agenti antibatterici
CN1119343C (zh) 1995-11-22 2003-08-27 第一制药株式会社 取代的氨基环烷基吡咯烷衍生物
WO1998018783A1 (fr) 1996-10-25 1998-05-07 Daiichi Pharmaceutical Co., Ltd. Derives d'amine tricycliques
US6274592B1 (en) 1997-02-04 2001-08-14 Senju Pharmaceutical Co., Ltd. Method for stabilizing arylcarboxylic acid, stabilizer thereof and aqueous solution containing stabilized arylcarboxylic acid
ID24434A (id) 1997-05-21 2000-07-20 Daiichi Seiyaku Co Derivat aminosikloalkilpirolidin tersubstitusi cis-tersubstitusi
ZA984527B (en) 1997-05-30 1998-12-03 Daiichi Seiyaku Co Substituted cyclobutylamine derivative
KR100241673B1 (ko) 1997-08-09 2000-03-02 김충섭 퀴놀리진 카르복실산 유도체
US6387928B1 (en) 1997-09-15 2002-05-14 The Procter & Gamble Co. Antimicrobial quinolones, their compositions and uses
HUP0100051A3 (en) 1997-09-15 2002-08-28 Procter & Gamble Antimicrobial quinolones, their compositions and uses
GB9822440D0 (en) 1998-10-14 1998-12-09 Smithkline Beecham Plc Medicaments
GB9914486D0 (en) 1999-06-21 1999-08-18 Smithkline Beecham Plc Medicaments
KR20020067701A (ko) 2000-01-24 2002-08-23 워너-램버트 캄파니 3-아미노퀴나졸린-2,4-디온 항균제
NZ525571A (en) 2000-12-14 2004-09-24 Procter & Gamble Antimicrobial quinolones
JP4250353B2 (ja) 2001-06-22 2009-04-08 エドワーズ株式会社 真空ポンプ
US6900224B2 (en) 2002-07-31 2005-05-31 The Procter & Gamble Company Antimicrobial quinolones, their compositions and uses
US6803469B2 (en) 2002-08-05 2004-10-12 The Procter & Gamble Company Process for preparing quinolone antibiotic intermediates
DE602004019555D1 (de) * 2003-09-22 2009-04-02 Janssen Pharmaceutica Nv Heterocyclische 7-aminoalkylidenylchinolone und -naphthyridone
US7732612B2 (en) 2004-09-09 2010-06-08 Janssen Pharmaceutica, N.V. 7-amino alkylidenyl-heterocyclic quinolones and naphthyridones
WO2007110835A2 (en) 2006-03-28 2007-10-04 The Procter & Gamble Company A coupling process for preparing quinolone intermediates
JP4876165B2 (ja) * 2006-03-28 2012-02-15 ザ プロクター アンド ギャンブル カンパニー キノロン中間体を調製するための水素化物還元法

Also Published As

Publication number Publication date
MY148393A (en) 2013-04-15
BRPI0709772B8 (pt) 2021-05-25
JP2009531417A (ja) 2009-09-03
CA2647346C (en) 2011-07-19
PE20080175A1 (es) 2008-03-14
US20070232650A1 (en) 2007-10-04
WO2007110834A3 (en) 2007-12-06
AR060189A1 (es) 2008-05-28
AU2007230630A1 (en) 2007-10-04
ES2366150T3 (es) 2011-10-17
KR20090004887A (ko) 2009-01-12
TWI364419B (en) 2012-05-21
MA30554B1 (fr) 2009-07-01
AU2007230630B2 (en) 2012-12-20
PL2001862T3 (pl) 2011-09-30
EP2001862B1 (en) 2011-04-27
IL193990A (en) 2014-12-31
MX2008012328A (es) 2008-10-09
HRP20110558T1 (hr) 2011-09-30
ATE507219T1 (de) 2011-05-15
SI2001862T1 (sl) 2011-10-28
SMAP200800058A (it) 2008-10-29
RU2008134544A (ru) 2010-05-10
KR101102288B1 (ko) 2012-01-03
US8039485B2 (en) 2011-10-18
EP2001862A2 (en) 2008-12-17
RU2417222C2 (ru) 2011-04-27
BRPI0709772A2 (pt) 2011-07-26
TW200808759A (en) 2008-02-16
CY1111683T1 (el) 2015-10-07
ZA200807158B (en) 2009-09-30
JP5097967B2 (ja) 2012-12-12
CA2647346A1 (en) 2007-10-04
DK2001862T3 (da) 2011-08-08
NZ570494A (en) 2011-09-30
WO2007110834A2 (en) 2007-10-04
BRPI0709772B1 (pt) 2019-10-15
DE602007014191D1 (en) 2011-06-09
SMP200800058B (it) 2009-09-07
AR060377A1 (es) 2008-06-11

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