PT1937301E - Partículas idênticas a vírus (vlps) da gripe funcionais - Google Patents

Partículas idênticas a vírus (vlps) da gripe funcionais Download PDF

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Publication number
PT1937301E
PT1937301E PT68262641T PT06826264T PT1937301E PT 1937301 E PT1937301 E PT 1937301E PT 68262641 T PT68262641 T PT 68262641T PT 06826264 T PT06826264 T PT 06826264T PT 1937301 E PT1937301 E PT 1937301E
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PT
Portugal
Prior art keywords
influenza
vlp
vlps
proteins
virus
Prior art date
Application number
PT68262641T
Other languages
English (en)
Portuguese (pt)
Inventor
Gale Smith
Peter Pushko
Rick Bright
Jinyou Zhang
Kutub Mahmood
Original Assignee
Novavax Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novavax Inc filed Critical Novavax Inc
Publication of PT1937301E publication Critical patent/PT1937301E/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • A61K39/145Orthomyxoviridae, e.g. influenza virus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/16Antivirals for RNA viruses for influenza or rhinoviruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C07K14/08RNA viruses
    • C07K14/11Orthomyxoviridae, e.g. influenza virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5258Virus-like particles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505Inorganic adjuvants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16123Virus like particles [VLP]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2760/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
    • C12N2760/00011Details
    • C12N2760/16011Orthomyxoviridae
    • C12N2760/16111Influenzavirus A, i.e. influenza A virus
    • C12N2760/16134Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
PT68262641T 2005-10-18 2006-10-18 Partículas idênticas a vírus (vlps) da gripe funcionais PT1937301E (pt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US72751305P 2005-10-18 2005-10-18
US78084706P 2006-03-10 2006-03-10
US80000606P 2006-05-15 2006-05-15
US83119606P 2006-07-17 2006-07-17
US83211606P 2006-07-21 2006-07-21
US84549506P 2006-09-19 2006-09-19

Publications (1)

Publication Number Publication Date
PT1937301E true PT1937301E (pt) 2015-09-14

Family

ID=37963272

Family Applications (1)

Application Number Title Priority Date Filing Date
PT68262641T PT1937301E (pt) 2005-10-18 2006-10-18 Partículas idênticas a vírus (vlps) da gripe funcionais

Country Status (19)

Country Link
EP (1) EP1937301B1 (cg-RX-API-DMAC7.html)
JP (5) JP5714799B2 (cg-RX-API-DMAC7.html)
KR (1) KR101359723B1 (cg-RX-API-DMAC7.html)
CN (2) CN103865892B (cg-RX-API-DMAC7.html)
AU (1) AU2006304640B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0617486A2 (cg-RX-API-DMAC7.html)
CA (1) CA2625406C (cg-RX-API-DMAC7.html)
DK (1) DK1937301T3 (cg-RX-API-DMAC7.html)
ES (1) ES2543056T3 (cg-RX-API-DMAC7.html)
HU (1) HUE026136T2 (cg-RX-API-DMAC7.html)
IL (1) IL190775A (cg-RX-API-DMAC7.html)
NZ (1) NZ567164A (cg-RX-API-DMAC7.html)
PL (1) PL1937301T3 (cg-RX-API-DMAC7.html)
PT (1) PT1937301E (cg-RX-API-DMAC7.html)
RU (1) RU2483751C2 (cg-RX-API-DMAC7.html)
SG (1) SG2014012868A (cg-RX-API-DMAC7.html)
SI (1) SI1937301T1 (cg-RX-API-DMAC7.html)
TW (1) TWI488968B (cg-RX-API-DMAC7.html)
WO (1) WO2007047831A2 (cg-RX-API-DMAC7.html)

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JP7568746B2 (ja) 2020-05-01 2024-10-16 神州細胞工程有限公司 タンパク質/ペプチド抗原の免疫原性を向上させる方法
CN112342149A (zh) * 2020-11-12 2021-02-09 新疆畜牧科学院兽医研究所(新疆畜牧科学院动物临床医学研究中心) 一种禽流感病毒样颗粒组装表达系统及其应用
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Also Published As

Publication number Publication date
AU2006304640A1 (en) 2007-04-26
IL190775A (en) 2016-04-21
BRPI0617486A2 (pt) 2011-07-26
TW200732476A (en) 2007-09-01
PL1937301T3 (pl) 2015-10-30
CA2625406C (en) 2016-08-09
JP5771558B2 (ja) 2015-09-02
ES2543056T3 (es) 2015-08-14
CA2625406A1 (en) 2007-04-26
NZ567164A (en) 2012-06-29
RU2008119501A (ru) 2009-11-27
KR20080081901A (ko) 2008-09-10
JP2009511084A (ja) 2009-03-19
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JP2017189178A (ja) 2017-10-19
SI1937301T1 (sl) 2015-08-31
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WO2007047831A3 (en) 2007-07-19
SG2014012868A (en) 2014-09-26
JP2012157367A (ja) 2012-08-23
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JP2016135142A (ja) 2016-07-28
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AU2006304640B2 (en) 2012-10-11
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EP1937301A2 (en) 2008-07-02
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