PT1343782E - Pirimidinoaminas como moduladores de angiogénese - Google Patents

Pirimidinoaminas como moduladores de angiogénese Download PDF

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Publication number
PT1343782E
PT1343782E PT01994315T PT01994315T PT1343782E PT 1343782 E PT1343782 E PT 1343782E PT 01994315 T PT01994315 T PT 01994315T PT 01994315 T PT01994315 T PT 01994315T PT 1343782 E PT1343782 E PT 1343782E
Authority
PT
Portugal
Prior art keywords
pyrimidineamines
angiogenesis modulators
pyrimidine derivatives
angiogenesis
modulators
Prior art date
Application number
PT01994315T
Other languages
English (en)
Portuguese (pt)
Inventor
Philip Anthony Harris
Amogh Boloor
Mui Cheung
Ronda Davis
Kevin Hinkle
Robert Anthony Mook Jr
Jeffery Alan Stafford
James Martin Veal
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26946028&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT1343782(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of PT1343782E publication Critical patent/PT1343782E/pt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/30—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/10—Ophthalmic agents for accommodation disorders, e.g. myopia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/08—Radicals containing only hydrogen and carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
PT01994315T 2000-12-21 2001-12-19 Pirimidinoaminas como moduladores de angiogénese PT1343782E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25752600P 2000-12-21 2000-12-21
US26240301P 2001-01-16 2001-01-16

Publications (1)

Publication Number Publication Date
PT1343782E true PT1343782E (pt) 2009-06-29

Family

ID=26946028

Family Applications (2)

Application Number Title Priority Date Filing Date
PT01994315T PT1343782E (pt) 2000-12-21 2001-12-19 Pirimidinoaminas como moduladores de angiogénese
PT91591388T PT2311825E (pt) 2000-12-21 2001-12-19 Piramidinaminas como moduladores da angiogénese

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT91591388T PT2311825E (pt) 2000-12-21 2001-12-19 Piramidinaminas como moduladores da angiogénese

Country Status (27)

Country Link
US (6) US7105530B2 (cg-RX-API-DMAC10.html)
EP (2) EP1343782B1 (cg-RX-API-DMAC10.html)
JP (1) JP4253188B2 (cg-RX-API-DMAC10.html)
KR (1) KR100847169B1 (cg-RX-API-DMAC10.html)
CN (1) CN1307173C (cg-RX-API-DMAC10.html)
AT (1) ATE430742T1 (cg-RX-API-DMAC10.html)
AU (1) AU2002246723B2 (cg-RX-API-DMAC10.html)
BE (1) BE2010C030I2 (cg-RX-API-DMAC10.html)
BR (1) BR0116452A (cg-RX-API-DMAC10.html)
CA (1) CA2432000C (cg-RX-API-DMAC10.html)
CY (2) CY1109160T1 (cg-RX-API-DMAC10.html)
CZ (1) CZ304059B6 (cg-RX-API-DMAC10.html)
DE (2) DE122010000038I1 (cg-RX-API-DMAC10.html)
DK (2) DK2311825T3 (cg-RX-API-DMAC10.html)
ES (2) ES2556946T3 (cg-RX-API-DMAC10.html)
FR (1) FR10C0037I2 (cg-RX-API-DMAC10.html)
HU (2) HU230574B1 (cg-RX-API-DMAC10.html)
IL (2) IL156306A0 (cg-RX-API-DMAC10.html)
LU (1) LU91710I2 (cg-RX-API-DMAC10.html)
MX (1) MXPA03005696A (cg-RX-API-DMAC10.html)
NO (3) NO325987B1 (cg-RX-API-DMAC10.html)
NZ (1) NZ526542A (cg-RX-API-DMAC10.html)
PL (1) PL214667B1 (cg-RX-API-DMAC10.html)
PT (2) PT1343782E (cg-RX-API-DMAC10.html)
SI (2) SI1343782T1 (cg-RX-API-DMAC10.html)
WO (1) WO2002059110A1 (cg-RX-API-DMAC10.html)
ZA (1) ZA200304482B (cg-RX-API-DMAC10.html)

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