PL3272764T3 - Sposób chromatografii powinowactwa - Google Patents
Sposób chromatografii powinowactwaInfo
- Publication number
- PL3272764T3 PL3272764T3 PL17188657.5T PL17188657T PL3272764T3 PL 3272764 T3 PL3272764 T3 PL 3272764T3 PL 17188657 T PL17188657 T PL 17188657T PL 3272764 T3 PL3272764 T3 PL 3272764T3
- Authority
- PL
- Poland
- Prior art keywords
- affinity chromatography
- affinity
- chromatography
- Prior art date
Links
- 238000001042 affinity chromatography Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 and B01D15/30 - B01D15/36, e.g. affinity, ligand exchange or chiral chromatography
- B01D15/3804—Affinity chromatography
- B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G or L chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US28805909P | 2009-12-18 | 2009-12-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PL3272764T3 true PL3272764T3 (pl) | 2024-06-10 |
Family
ID=43598315
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL17188657.5T PL3272764T3 (pl) | 2009-12-18 | 2010-12-17 | Sposób chromatografii powinowactwa |
| PL10790452T PL2513134T3 (pl) | 2009-12-18 | 2010-12-17 | Roztwór do przemywania i sposób chromatografii powinowactwa |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL10790452T PL2513134T3 (pl) | 2009-12-18 | 2010-12-17 | Roztwór do przemywania i sposób chromatografii powinowactwa |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US9505803B2 (enExample) |
| EP (2) | EP2513134B1 (enExample) |
| JP (2) | JP5909450B2 (enExample) |
| KR (1) | KR101858266B1 (enExample) |
| CN (1) | CN102725304B (enExample) |
| AU (1) | AU2010332778B2 (enExample) |
| BR (1) | BR112012014937B1 (enExample) |
| CA (1) | CA2784278C (enExample) |
| DK (2) | DK2513134T3 (enExample) |
| ES (2) | ES2651065T3 (enExample) |
| IL (1) | IL220164B (enExample) |
| LT (2) | LT2513134T (enExample) |
| MX (1) | MX2012007103A (enExample) |
| PL (2) | PL3272764T3 (enExample) |
| PT (2) | PT3272764T (enExample) |
| RU (1) | RU2564569C2 (enExample) |
| SG (2) | SG10201408384PA (enExample) |
| WO (1) | WO2011073389A1 (enExample) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8911964B2 (en) | 2006-09-13 | 2014-12-16 | Abbvie Inc. | Fed-batch method of making human anti-TNF-alpha antibody |
| EP2500413A1 (en) | 2006-09-13 | 2012-09-19 | Abbott Laboratories | Cell culture improvements |
| NZ592097A (en) | 2008-10-20 | 2013-01-25 | Abbott Lab | Viral inactivation during purification of il-12 and il-18 antibodies |
| KR20110091678A (ko) * | 2008-10-20 | 2011-08-12 | 아보트 러보러터리즈 | 단백질 a 친화성 크로마토그래피를 이용한 항체의 분리 및 정제 |
| JP5909450B2 (ja) * | 2009-12-18 | 2016-04-26 | ノバルティス アーゲー | 洗浄溶液及びアフィニティークロマトグラフィーの方法 |
| ES2492681T3 (es) * | 2010-01-22 | 2014-09-10 | Boehringer Ingelheim International Gmbh | Método cromatográfico para purificar proteínas que contienen FC |
| CA2834300C (en) * | 2011-06-01 | 2022-01-11 | Novartis Ag | Wash solution and method for affinity chromatography |
| ES2971444T3 (es) | 2011-10-11 | 2024-06-05 | F Hoffmann Lar Roche Ag | Ensamblaje mejorado de anticuerpos biespecíficos |
| EP2997036B1 (en) | 2013-05-15 | 2021-03-03 | Medimmune Limited | Purification of recombinantly produced polypeptides |
| EP3041593B1 (en) * | 2013-09-05 | 2025-01-29 | F. Hoffmann-La Roche AG | Method of cleaning a chromatography material for its reuse |
| EP2986307A4 (en) | 2014-01-03 | 2017-04-12 | Bio-rad Laboratories, Inc. | Removal of impurities from protein a eluates |
| US11566082B2 (en) | 2014-11-17 | 2023-01-31 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| KR102490956B1 (ko) | 2015-03-13 | 2023-01-19 | 브리스톨-마이어스 스큅 컴퍼니 | 불순물을 제거하기 위한 크로마토그래피 동안의 알칼리성 세척의 용도 |
| PL3337812T3 (pl) | 2015-08-21 | 2021-10-11 | F. Hoffmann-La Roche Ag | Sposób zmniejszenia zawartości białek komórki gospodarza w chromatografii powinowactwa |
| CN107849122B (zh) * | 2015-08-21 | 2022-01-25 | 豪夫迈·罗氏有限公司 | 用低电导率洗涤缓冲液进行亲和层析纯化 |
| US10889615B2 (en) | 2016-05-11 | 2021-01-12 | Cytiva Bioprocess R&D Ab | Mutated immunoglobulin-binding polypeptides |
| US10703774B2 (en) | 2016-09-30 | 2020-07-07 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| US11708390B2 (en) | 2016-05-11 | 2023-07-25 | Cytiva Bioprocess R&D Ab | Method of storing a separation matrix |
| US10654887B2 (en) | 2016-05-11 | 2020-05-19 | Ge Healthcare Bio-Process R&D Ab | Separation matrix |
| JP7031934B2 (ja) | 2016-05-11 | 2022-03-08 | サイティバ・バイオプロセス・アールアンドディ・アクチボラグ | 分離マトリックス |
| EP3455243B1 (en) | 2016-05-11 | 2021-03-24 | Cytiva BioProcess R&D AB | Separation matrix |
| ES2909833T3 (es) | 2016-05-11 | 2022-05-10 | Cytiva Bioprocess R & D Ab | Método de limpieza y/o desinfección de una matriz de separación |
| US10730908B2 (en) | 2016-05-11 | 2020-08-04 | Ge Healthcare Bioprocess R&D Ab | Separation method |
| MX392628B (es) * | 2016-07-25 | 2025-03-24 | Cephalon Inc | Amortiguador de lavado de cromatografia de afinidad. |
| US12448411B2 (en) | 2016-09-30 | 2025-10-21 | Cytiva Bioprocess R&D Ab | Separation method |
| CA3067735A1 (en) | 2017-08-17 | 2019-02-21 | Just Biotherapeutics, Inc. | Method of purifying glycosylated protein from host cell galectins and other contaminants |
| CN107793469B (zh) * | 2017-10-16 | 2021-07-30 | 上海药明生物技术有限公司 | 一种去除宿主细胞蛋白含量的亲和纯化工艺 |
| AU2018392697B2 (en) * | 2017-12-21 | 2025-08-14 | Genzyme Corporation | Methods for enhanced removal of impurities during protein a chromatography |
| CN119881293A (zh) | 2018-03-21 | 2025-04-25 | 沃特世科技公司 | 基于非抗体高亲和力的样品制备、吸附剂、装置和方法 |
| BR112020019882A2 (pt) | 2018-04-02 | 2021-01-05 | Amgen Inc. | Composições de erenumabe e seus usos |
| EP3791172B1 (en) * | 2018-05-08 | 2023-06-28 | Waters Technologies Corporation | Methods, compositions and kits useful for ph gradient cation exchange chromatography |
| EP3837273B1 (en) * | 2018-08-14 | 2025-09-24 | Bristol-Myers Squibb Company | Improved protein recovery |
| US20230399358A1 (en) * | 2019-10-08 | 2023-12-14 | North Carolina State University | Immunoglobulin purification peptides and their use |
| CA3176109A1 (en) * | 2020-03-27 | 2021-09-30 | Haemalogix Pty Ltd | Composition and method |
| JP2023523324A (ja) * | 2020-04-27 | 2023-06-02 | アレクシオン ファーマシューティカルズ, インコーポレイテッド | 抗体のプロテインaクロマトグラフィー精製 |
| CN112827217A (zh) * | 2020-12-29 | 2021-05-25 | 苏州良辰生物医药科技有限公司 | 一种层析柱清洗液及其应用 |
| CR20250204A (es) * | 2022-12-12 | 2025-06-06 | H Lundbeck As | Lavado con arginina en la purificación de proteínas |
| WO2024233992A2 (en) * | 2023-05-11 | 2024-11-14 | Trophogen, Inc. | Methods of manufacturing highly glycosylated glycoprotein hormones and their analogs |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4704366A (en) | 1984-06-22 | 1987-11-03 | Bio-Rad Laboratories, Inc. | Process for binding IgG to protein A |
| US4857320A (en) * | 1987-02-19 | 1989-08-15 | Monsanto Company | Method of enhancing the solubility of tissue plasminogen activator |
| JPH01238534A (ja) * | 1988-03-17 | 1989-09-22 | Mitsui Toatsu Chem Inc | エンドトキシンの除去方法 |
| US5429746A (en) | 1994-02-22 | 1995-07-04 | Smith Kline Beecham Corporation | Antibody purification |
| JP4031049B2 (ja) | 1996-11-27 | 2008-01-09 | ジェネンテック,インコーポレーテッド | タンパク質精製 |
| ATE321066T1 (de) | 1998-05-06 | 2006-04-15 | Genentech Inc | Anti-her2 antikörperzusammensetzung |
| DE69919701T2 (de) | 1998-06-01 | 2005-09-15 | Genentech, Inc., South San Francisco | Abtrennung von antikörper-monomeren von deren multimeren mittels ionaustausch-chromatographie |
| WO2002072615A1 (en) | 2001-03-09 | 2002-09-19 | Chugai Seiyaku Kabushiki Kaisha | Method of purifying protein |
| DK1714982T3 (da) | 2001-06-05 | 2009-05-04 | Genetics Inst Llc | Fremgangsmåde til rensning af stærkt anioniske proteiner |
| JP4460302B2 (ja) | 2002-02-05 | 2010-05-12 | ジェネンテック インコーポレイテッド | タンパク質精製法 |
| SI1561756T1 (sl) | 2002-09-11 | 2016-02-29 | Chugai Seiyaku Kabushiki Kaisha | Postopek čiščenja proteinov |
| MXPA05004290A (es) * | 2002-10-24 | 2005-11-23 | Enos Pharmaceuticals Inc | Formulaciones de l-arginina de liberacion sostenida, y metodos para su fabricacion y uso. |
| MXPA05005558A (es) * | 2002-11-26 | 2005-07-26 | Protein Design Labs Inc | Anticuerpos quimericos y humanizados para integrina ( 5 ( 1 que modulan la angiogenesis. |
| WO2004062689A1 (en) * | 2003-01-08 | 2004-07-29 | Chiron Corporation | Stabilized aqueous compositions comprising tissue factor pathway inhibitor (tfpi) or tissue factor pathway inhibitor variant |
| GB0304576D0 (en) | 2003-02-28 | 2003-04-02 | Lonza Biologics Plc | Protein a chromatography |
| EP1601697B1 (en) | 2003-02-28 | 2007-05-30 | Lonza Biologics plc | Antibody purification by Protein A and ion exchange chromatography |
| AU2004286938B2 (en) | 2003-10-27 | 2011-06-30 | Wyeth | Removal of high molecular weight aggregates using hydroxyapatite chromatography |
| US8084032B2 (en) | 2004-01-21 | 2011-12-27 | Ajinomoto Co., Inc. | Purification method which prevents denaturation of an antibody |
| DE602006003108D1 (de) | 2005-03-03 | 2008-11-27 | Ajinomoto Kk | Methode zur Verbesserung der Ausbeute bei der Proteinreinigung mittels Gelfiltrationschromatographie und Arginin |
| KR101482791B1 (ko) * | 2005-03-11 | 2015-01-21 | 와이어쓰 엘엘씨 | 약한 분배성 크로마토그래피법 |
| CN101365948B (zh) | 2006-01-06 | 2012-11-07 | Emd密理博公司 | 亲和层析基质及其制备和使用方法 |
| US8263750B2 (en) | 2006-03-16 | 2012-09-11 | Amgen Inc. | Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step |
| WO2007108955A1 (en) | 2006-03-20 | 2007-09-27 | Medarex, Inc. | Protein purification |
| US7754689B2 (en) | 2006-06-02 | 2010-07-13 | Wyeth Llc | Finger-1 peptide analogs of the TGF-β superfamily |
| AU2007254824A1 (en) * | 2006-06-02 | 2007-12-13 | Wyeth | Use of proteins and peptides of the TGF-beta superfamily for purification and therapeutic methods |
| ES2755386T5 (es) | 2006-08-28 | 2023-04-05 | Ares Trading Sa | Proceso para la purificación de proteínas que contienen fragmentos Fc |
| CL2007002615A1 (es) | 2006-09-08 | 2008-04-18 | Wyeth Corp | Metodos para aislar o purificar un producto que comprende poner el producto enlazado en contacto con al menos una solucion de lavado que comprende arginina y luego eluir el producto; y dicho producto. |
| JP2010516651A (ja) | 2007-01-17 | 2010-05-20 | メルク セローノ ソシエテ アノニム | Fc含有タンパク質の精製のための方法 |
| MX2009012786A (es) | 2007-06-01 | 2009-12-10 | Hoffmann La Roche | Purificacion de inmunoglobulina. |
| US20110105725A1 (en) | 2008-05-15 | 2011-05-05 | Novo Nordisk A/S | Antibody purification process |
| JP5529869B2 (ja) | 2008-08-14 | 2014-06-25 | メルク・シャープ・アンド・ドーム・コーポレーション | プロテインaアフィニティークロマトグラフィーを用いる抗体の精製方法 |
| JP5909450B2 (ja) | 2009-12-18 | 2016-04-26 | ノバルティス アーゲー | 洗浄溶液及びアフィニティークロマトグラフィーの方法 |
| CA2834300C (en) | 2011-06-01 | 2022-01-11 | Novartis Ag | Wash solution and method for affinity chromatography |
-
2010
- 2010-12-17 JP JP2012543787A patent/JP5909450B2/ja active Active
- 2010-12-17 LT LTEP10790452.6T patent/LT2513134T/lt unknown
- 2010-12-17 SG SG10201408384PA patent/SG10201408384PA/en unknown
- 2010-12-17 SG SG2012044707A patent/SG181771A1/en unknown
- 2010-12-17 PL PL17188657.5T patent/PL3272764T3/pl unknown
- 2010-12-17 ES ES10790452.6T patent/ES2651065T3/es active Active
- 2010-12-17 CA CA2784278A patent/CA2784278C/en active Active
- 2010-12-17 LT LTEP17188657.5T patent/LT3272764T/lt unknown
- 2010-12-17 PT PT171886575T patent/PT3272764T/pt unknown
- 2010-12-17 CN CN201080057457.6A patent/CN102725304B/zh active Active
- 2010-12-17 EP EP10790452.6A patent/EP2513134B1/en not_active Revoked
- 2010-12-17 MX MX2012007103A patent/MX2012007103A/es unknown
- 2010-12-17 DK DK10790452.6T patent/DK2513134T3/en active
- 2010-12-17 DK DK17188657.5T patent/DK3272764T3/da active
- 2010-12-17 BR BR112012014937-7A patent/BR112012014937B1/pt active IP Right Grant
- 2010-12-17 WO PCT/EP2010/070076 patent/WO2011073389A1/en not_active Ceased
- 2010-12-17 KR KR1020127015524A patent/KR101858266B1/ko active Active
- 2010-12-17 US US13/516,960 patent/US9505803B2/en active Active
- 2010-12-17 PT PT107904526T patent/PT2513134T/pt unknown
- 2010-12-17 AU AU2010332778A patent/AU2010332778B2/en active Active
- 2010-12-17 PL PL10790452T patent/PL2513134T3/pl unknown
- 2010-12-17 RU RU2012130151/10A patent/RU2564569C2/ru active
- 2010-12-17 ES ES17188657T patent/ES2982297T3/es active Active
- 2010-12-17 EP EP17188657.5A patent/EP3272764B1/en active Active
-
2012
- 2012-06-04 IL IL220164A patent/IL220164B/en active IP Right Grant
-
2016
- 2016-02-08 JP JP2016021798A patent/JP2016128495A/ja active Pending
- 2016-10-28 US US15/336,878 patent/US20170044211A1/en not_active Abandoned
-
2019
- 2019-03-25 US US16/363,170 patent/US20190233469A1/en not_active Abandoned
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