PT2513134T - Solução de lavagem e método para cromatografia de afinidade - Google Patents

Solução de lavagem e método para cromatografia de afinidade

Info

Publication number
PT2513134T
PT2513134T PT107904526T PT10790452T PT2513134T PT 2513134 T PT2513134 T PT 2513134T PT 107904526 T PT107904526 T PT 107904526T PT 10790452 T PT10790452 T PT 10790452T PT 2513134 T PT2513134 T PT 2513134T
Authority
PT
Portugal
Prior art keywords
affinity chromatography
wash solution
wash
solution
affinity
Prior art date
Application number
PT107904526T
Other languages
English (en)
Inventor
Frauenschuh Achim
Bill Kurt
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43598315&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2513134(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT2513134T publication Critical patent/PT2513134T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT107904526T 2009-12-18 2010-12-17 Solução de lavagem e método para cromatografia de afinidade PT2513134T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28805909P 2009-12-18 2009-12-18

Publications (1)

Publication Number Publication Date
PT2513134T true PT2513134T (pt) 2017-12-14

Family

ID=43598315

Family Applications (2)

Application Number Title Priority Date Filing Date
PT171886575T PT3272764T (pt) 2009-12-18 2010-12-17 Método para cromatografia de afinidade
PT107904526T PT2513134T (pt) 2009-12-18 2010-12-17 Solução de lavagem e método para cromatografia de afinidade

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT171886575T PT3272764T (pt) 2009-12-18 2010-12-17 Método para cromatografia de afinidade

Country Status (18)

Country Link
US (3) US9505803B2 (pt)
EP (2) EP2513134B1 (pt)
JP (2) JP5909450B2 (pt)
KR (1) KR101858266B1 (pt)
CN (1) CN102725304B (pt)
AU (1) AU2010332778B2 (pt)
BR (1) BR112012014937B1 (pt)
CA (1) CA2784278C (pt)
DK (2) DK3272764T3 (pt)
ES (1) ES2651065T3 (pt)
IL (1) IL220164B (pt)
LT (2) LT3272764T (pt)
MX (1) MX2012007103A (pt)
PL (2) PL3272764T3 (pt)
PT (2) PT3272764T (pt)
RU (1) RU2564569C2 (pt)
SG (2) SG10201408384PA (pt)
WO (1) WO2011073389A1 (pt)

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CN104974251A (zh) 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
WO2011073389A1 (en) * 2009-12-18 2011-06-23 Novartis Ag Wash solution and method for affinity chromatography
CN102712673B (zh) * 2010-01-22 2014-04-30 贝林格尔.英格海姆国际有限公司 用于纯化含fc的蛋白的色谱方法
CA2834300C (en) * 2011-06-01 2022-01-11 Novartis Ag Wash solution and method for affinity chromatography
CN104093744A (zh) 2011-10-11 2014-10-08 弗·哈夫曼-拉罗切有限公司 双特异性抗体的改进的组装
CA2910065C (en) * 2013-05-15 2023-09-19 Medimmune Limited Purification of recombinantly produced polypeptides
CA2922832A1 (en) * 2013-09-05 2015-03-12 Genentech, Inc. Method for chromatography reuse
CN105407905B (zh) 2014-01-03 2020-03-03 生物辐射实验室股份有限公司 蛋白a洗脱产物中杂质的去除
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
JP6807859B2 (ja) 2015-03-13 2021-01-06 ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ クロマトグラフィーにおける不純物を取り除くためのアルカリ洗浄の使用
WO2017032686A1 (en) 2015-08-21 2017-03-02 F. Hoffmann-La Roche Ag Method for the reduction of host cell proteins in affinity chromatography
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US11753438B2 (en) 2016-05-11 2023-09-12 Cytiva Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US10513537B2 (en) 2016-05-11 2019-12-24 Ge Healthcare Bioprocess R&D Ab Separation matrix
WO2017194592A1 (en) 2016-05-11 2017-11-16 Ge Healthcare Bioprocess R&D Ab Method of storing a separation matrix
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
US10688412B2 (en) * 2016-07-25 2020-06-23 Cehpalon, Inc. Affinity chromatography wash buffer
CA3067735A1 (en) 2017-08-17 2019-02-21 Just Biotherapeutics, Inc. Method of purifying glycosylated protein from host cell galectins and other contaminants
CN107793469B (zh) * 2017-10-16 2021-07-30 上海药明生物技术有限公司 一种去除宿主细胞蛋白含量的亲和纯化工艺
KR20200103740A (ko) * 2017-12-21 2020-09-02 젠자임 코포레이션 단백질 a 크로마토그래피 동안 불순물의 향상된 제거를 위한 방법
CN111902720A (zh) 2018-03-21 2020-11-06 沃特世科技公司 基于非抗体高亲和力的样品制备、吸附剂、装置和方法
AR114722A1 (es) 2018-04-02 2020-10-07 Amgen Inc Composiciones de erenumab y usos de las mismas
EP3791172B1 (en) * 2018-05-08 2023-06-28 Waters Technologies Corporation Methods, compositions and kits useful for ph gradient cation exchange chromatography
JP2022551837A (ja) * 2019-10-08 2022-12-14 ノース カロライナ ステート ユニバーシティ 免疫グロブリン精製ペプチド、及びその使用
JP2023518905A (ja) * 2020-03-27 2023-05-08 ハエマロジックス・リミテッド 組成物および方法
EP4143203A1 (en) * 2020-04-27 2023-03-08 Alexion Pharmaceuticals, Inc. Protein a chromatography purification of an antibody
CN112827217A (zh) * 2020-12-29 2021-05-25 苏州良辰生物医药科技有限公司 一种层析柱清洗液及其应用
WO2024126337A1 (en) * 2022-12-12 2024-06-20 H. Lundbeck A/S Arginine wash in protein purification

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US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
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US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
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BRPI9910332B8 (pt) 1998-05-06 2021-05-25 Genentech Inc método para purificação de um polipeptídio a partir de uma composição
EP1500661A1 (en) 1998-06-01 2005-01-26 Genetech, Inc. Separation of protein monomers from aggregates by use of ion-exchange chromatography
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AU2007254824A1 (en) * 2006-06-02 2007-12-13 Wyeth Use of proteins and peptides of the TGF-beta superfamily for purification and therapeutic methods
US7754689B2 (en) * 2006-06-02 2010-07-13 Wyeth Llc Finger-1 peptide analogs of the TGF-β superfamily
FI2061803T4 (fi) 2006-08-28 2023-03-14 Process for the purification of fc-containing proteins
TW200821026A (en) 2006-09-08 2008-05-16 Wyeth Corp Arginine wash in protein purification using affinity chromatography
JP2010516651A (ja) 2007-01-17 2010-05-20 メルク セローノ ソシエテ アノニム Ｆｃ含有タンパク質の精製のための方法
AU2008256411B2 (en) 2007-06-01 2013-08-22 F. Hoffmann-La Roche Ag Immunoglobulin purification
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CA2834300C (en) 2011-06-01 2022-01-11 Novartis Ag Wash solution and method for affinity chromatography

Also Published As

Publication number Publication date
CA2784278C (en) 2019-02-26
PL2513134T3 (pl) 2018-02-28
WO2011073389A1 (en) 2011-06-23
US20120283416A1 (en) 2012-11-08
EP3272764B1 (en) 2024-02-07
KR101858266B1 (ko) 2018-05-15
BR112012014937B1 (pt) 2021-01-19
EP2513134B1 (en) 2017-09-06
LT3272764T (lt) 2024-05-10
CA2784278A1 (en) 2011-06-23
DK2513134T3 (en) 2017-12-18
BR112012014937A2 (pt) 2016-03-08
MX2012007103A (es) 2012-07-17
IL220164B (en) 2019-02-28
EP2513134A1 (en) 2012-10-24
ES2651065T3 (es) 2018-01-24
JP2016128495A (ja) 2016-07-14
US20170044211A1 (en) 2017-02-16
DK3272764T3 (da) 2024-05-06
LT2513134T (lt) 2017-11-27
US9505803B2 (en) 2016-11-29
JP5909450B2 (ja) 2016-04-26
SG10201408384PA (en) 2015-01-29
US20190233469A1 (en) 2019-08-01
JP2013514073A (ja) 2013-04-25
AU2010332778B2 (en) 2015-03-19
EP3272764A1 (en) 2018-01-24
KR20120109506A (ko) 2012-10-08
CN102725304B (zh) 2015-12-09
CN102725304A (zh) 2012-10-10
IL220164A0 (en) 2012-07-31
PL3272764T3 (pl) 2024-06-10
RU2564569C2 (ru) 2015-10-10
SG181771A1 (en) 2012-07-30
RU2012130151A (ru) 2014-01-27
AU2010332778A1 (en) 2012-07-19
PT3272764T (pt) 2024-04-24

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