PT3272764T - Método para cromatografia de afinidade - Google Patents

Método para cromatografia de afinidade

Info

Publication number
PT3272764T
PT3272764T PT171886575T PT17188657T PT3272764T PT 3272764 T PT3272764 T PT 3272764T PT 171886575 T PT171886575 T PT 171886575T PT 17188657 T PT17188657 T PT 17188657T PT 3272764 T PT3272764 T PT 3272764T
Authority
PT
Portugal
Prior art keywords
affinity chromatography
affinity
chromatography
Prior art date
Application number
PT171886575T
Other languages
English (en)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43598315&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT3272764(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PT3272764T publication Critical patent/PT3272764T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography
    • B01D15/3809—Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT171886575T 2009-12-18 2010-12-17 Método para cromatografia de afinidade PT3272764T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28805909P 2009-12-18 2009-12-18

Publications (1)

Publication Number Publication Date
PT3272764T true PT3272764T (pt) 2024-04-24

Family

ID=43598315

Family Applications (2)

Application Number Title Priority Date Filing Date
PT171886575T PT3272764T (pt) 2009-12-18 2010-12-17 Método para cromatografia de afinidade
PT107904526T PT2513134T (pt) 2009-12-18 2010-12-17 Solução de lavagem e método para cromatografia de afinidade

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT107904526T PT2513134T (pt) 2009-12-18 2010-12-17 Solução de lavagem e método para cromatografia de afinidade

Country Status (18)

Country Link
US (3) US9505803B2 (pt)
EP (2) EP3272764B1 (pt)
JP (2) JP5909450B2 (pt)
KR (1) KR101858266B1 (pt)
CN (1) CN102725304B (pt)
AU (1) AU2010332778B2 (pt)
BR (1) BR112012014937B1 (pt)
CA (1) CA2784278C (pt)
DK (2) DK3272764T3 (pt)
ES (1) ES2651065T3 (pt)
IL (1) IL220164B (pt)
LT (2) LT2513134T (pt)
MX (1) MX2012007103A (pt)
PL (1) PL2513134T3 (pt)
PT (2) PT3272764T (pt)
RU (1) RU2564569C2 (pt)
SG (2) SG10201408384PA (pt)
WO (1) WO2011073389A1 (pt)

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SG10201702922VA (en) * 2008-10-20 2017-06-29 Abbvie Inc Isolation and purification of antibodies using protein a affinity chromatography
CN104974251A (zh) 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
SG10201408384PA (en) * 2009-12-18 2015-01-29 Novartis Ag Wash solution and method for affinity chromatography
US9284347B2 (en) 2010-01-22 2016-03-15 Boehringer Ingelheim International Gmbh Chromatographic method for purifying FC-containing proteins
MX341620B (es) * 2011-06-01 2016-08-26 Novartis Ag Solucion y metodo de lavado para cromatografia de afinidad.
KR102492792B1 (ko) 2011-10-11 2023-01-30 제넨테크, 인크. 이중특이적 항체의 개선된 어셈블리
US10259842B2 (en) * 2013-05-15 2019-04-16 Medimmune, Llc Purification of recombinantly produced polypeptides
JP6602765B2 (ja) * 2013-09-05 2019-11-06 ジェネンテック， インコーポレイテッド クロマトグラフィー再使用のための方法
US9546208B2 (en) 2014-01-03 2017-01-17 Bio-Rad Laboratories, Inc. Removal of impurities from protein A eluates
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
AU2016233557B2 (en) 2015-03-13 2021-06-24 Bristol-Myers Squibb Company Use of alkaline washes during chromatography to remove impurities
ES2877532T3 (es) 2015-08-21 2021-11-17 Hoffmann La Roche Procedimiento para la reducción de proteínas de célula huésped en cromatografía de afinidad
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
JP7106187B2 (ja) 2016-05-11 2022-07-26 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックスを保存する方法
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US11753438B2 (en) 2016-05-11 2023-09-12 Cytiva Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
CN109071613A (zh) 2016-05-11 2018-12-21 通用电气医疗集团生物工艺研发股份公司 分离基质
EP3487868A4 (en) * 2016-07-25 2020-07-29 Cephalon, Inc. WASHING PAD FOR AFFINITY CHROMATOGRAPHY
EP3668985B1 (en) 2017-08-17 2021-06-16 Just-Evotec Biologics, Inc. Method of purifying glycosylated protein from host cell galectins and other contaminants
CN107793469B (zh) * 2017-10-16 2021-07-30 上海药明生物技术有限公司 一种去除宿主细胞蛋白含量的亲和纯化工艺
CA3086186A1 (en) * 2017-12-21 2019-06-27 Genzyme Corporation Methods for enhanced removal of impurities during protein a chromatography
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
SG11202009629YA (en) 2018-04-02 2020-10-29 Amgen Inc Erenumab compositions and uses thereof
EP3791172B1 (en) * 2018-05-08 2023-06-28 Waters Technologies Corporation Methods, compositions and kits useful for ph gradient cation exchange chromatography
CA3150215A1 (en) * 2019-10-08 2021-04-15 Stefano Menegatti Immunoglobulin purification peptides and their use
EP4126900A4 (en) * 2020-03-27 2024-05-29 HaemaLogiX Ltd COMPOSITION AND METHOD
WO2021222120A1 (en) * 2020-04-27 2021-11-04 Alexion Pharmaceuticals, Inc. Protein a chromatography purification of an antibody
CN112827217A (zh) * 2020-12-29 2021-05-25 苏州良辰生物医药科技有限公司 一种层析柱清洗液及其应用

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US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
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US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
PT1864999E (pt) 1996-11-27 2009-06-25 Genentech Inc Purificação por afinidade de um polipéptido numa matriz de proteína a
DE69936946T2 (de) 1998-05-06 2008-05-15 Genentech, Inc., South San Francisco Reinigung von Antikörpern durch Ionenaustauschchromatographie
CA2333747C (en) 1998-06-01 2008-02-19 Genentech, Inc. Separation of protein monomers by use of ion-exchange chromatography
EP2336149A1 (en) 2001-03-09 2011-06-22 Chugai Seiyaku Kabushiki Kaisha Protein purification method
ES2321539T3 (es) 2001-06-05 2009-06-08 Genetics Institute, Llc Procedimientos relativos a la purificacion de proteinas altamente anionicas.
JP4460302B2 (ja) 2002-02-05 2010-05-12 ジェネンテック インコーポレイテッド タンパク質精製法
DK2261230T3 (en) 2002-09-11 2017-06-12 Chugai Pharmaceutical Co Ltd Method of Protein Purification.
CA2503284A1 (en) * 2002-10-24 2004-05-06 Enos Pharmaceuticals, Inc. Sustained release l-arginine formulations and methods of manufacture and use
KR20110140143A (ko) * 2002-11-26 2011-12-30 애보트 바이오테라퓨틱스 코포레이션 혈관형성을 조절하는 α5β1 인테그린에 대한 키메라성 및 인간화 항체
ES2321297T3 (es) * 2003-01-08 2009-06-04 Novartis Vaccines And Diagnostics, Inc. Composiciones acuosas estabilizadas que comprenden inhibidor de la via del factor tisular (ivft) o variante del inhibidor de la via del factor tisular.
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PT1601697E (pt) 2003-02-28 2007-09-04 Lonza Biologics Plc Purificação de anticorpos através de proteína a e cromatografia de troca iónica.
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US8084032B2 (en) * 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
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MX2007011129A (es) * 2005-03-11 2007-11-06 Wyeth Corp Un metodo de cromatografia de particion debil.
EP1974215B1 (en) 2006-01-06 2017-12-27 EMD Millipore Corporation Affinity chromatography matrices and methods of making and using the same
US8263750B2 (en) 2006-03-16 2012-09-11 Amgen Inc. Method for purifying a protein using protein-A affinity chromatography using an intermediate wash step
WO2007108955A1 (en) 2006-03-20 2007-09-27 Medarex, Inc. Protein purification
US7754689B2 (en) * 2006-06-02 2010-07-13 Wyeth Llc Finger-1 peptide analogs of the TGF-β superfamily
EP2377876A1 (en) * 2006-06-02 2011-10-19 Wyeth LLC Use of proteins and peptides of the TGF-BETA superfamily for purification and therapeutic methods
JP2010501623A (ja) 2006-08-28 2010-01-21 アレス トレーディング ソシエテ アノニム Ｆｃ含有タンパク質の精製法
WO2008031020A2 (en) * 2006-09-08 2008-03-13 Wyeth Arginine wash in protein purification using affinity chromatography
US8168185B2 (en) 2007-01-17 2012-05-01 Merck Serono Sa Process for the purification of anti CD-25 antibodies
MX2009012786A (es) 2007-06-01 2009-12-10 Hoffmann La Roche Purificacion de inmunoglobulina.
CN102027010A (zh) 2008-05-15 2011-04-20 诺沃-诺迪斯克有限公司 抗体纯化方法
CA2733782A1 (en) 2008-08-14 2010-02-18 Merck Sharp & Dohme Corp. Methods for purifying antibodies using protein a affinity chromatography
SG10201408384PA (en) * 2009-12-18 2015-01-29 Novartis Ag Wash solution and method for affinity chromatography
MX341620B (es) 2011-06-01 2016-08-26 Novartis Ag Solucion y metodo de lavado para cromatografia de afinidad.

Also Published As

Publication number Publication date
DK3272764T3 (da) 2024-05-06
SG181771A1 (en) 2012-07-30
PL2513134T3 (pl) 2018-02-28
AU2010332778B2 (en) 2015-03-19
EP3272764B1 (en) 2024-02-07
ES2651065T3 (es) 2018-01-24
WO2011073389A1 (en) 2011-06-23
CN102725304B (zh) 2015-12-09
JP2013514073A (ja) 2013-04-25
SG10201408384PA (en) 2015-01-29
CN102725304A (zh) 2012-10-10
BR112012014937A2 (pt) 2016-03-08
JP2016128495A (ja) 2016-07-14
JP5909450B2 (ja) 2016-04-26
US9505803B2 (en) 2016-11-29
LT2513134T (lt) 2017-11-27
DK2513134T3 (en) 2017-12-18
US20120283416A1 (en) 2012-11-08
KR20120109506A (ko) 2012-10-08
US20190233469A1 (en) 2019-08-01
RU2012130151A (ru) 2014-01-27
KR101858266B1 (ko) 2018-05-15
AU2010332778A1 (en) 2012-07-19
EP2513134B1 (en) 2017-09-06
LT3272764T (lt) 2024-05-10
IL220164B (en) 2019-02-28
EP3272764A1 (en) 2018-01-24
EP2513134A1 (en) 2012-10-24
BR112012014937B1 (pt) 2021-01-19
PT2513134T (pt) 2017-12-14
MX2012007103A (es) 2012-07-17
IL220164A0 (en) 2012-07-31
CA2784278A1 (en) 2011-06-23
US20170044211A1 (en) 2017-02-16
RU2564569C2 (ru) 2015-10-10
CA2784278C (en) 2019-02-26

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