LT3272764T - Giminingumo chromatografijos metodas - Google Patents

Giminingumo chromatografijos metodas

Info

Publication number
LT3272764T
LT3272764T LTEP17188657.5T LT17188657T LT3272764T LT 3272764 T LT3272764 T LT 3272764T LT 17188657 T LT17188657 T LT 17188657T LT 3272764 T LT3272764 T LT 3272764T
Authority
LT
Lithuania
Prior art keywords
affinity chromatography
affinity
chromatography
Prior art date
Application number
LTEP17188657.5T
Other languages
English (en)
Inventor
Achim Frauenschuh
Kurt Bill
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43598315&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT3272764(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of LT3272764T publication Critical patent/LT3272764T/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/16Extraction; Separation; Purification by chromatography
    • C07K1/22Affinity chromatography or related techniques based upon selective absorption processes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804Affinity chromatography
    • B01D15/3809Affinity chromatography of the antigen-antibody type, e.g. protein A, G, L chromatography
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
LTEP17188657.5T 2009-12-18 2010-12-17 Giminingumo chromatografijos metodas LT3272764T (lt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28805909P 2009-12-18 2009-12-18

Publications (1)

Publication Number Publication Date
LT3272764T true LT3272764T (lt) 2024-05-10

Family

ID=43598315

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17188657.5T LT3272764T (lt) 2009-12-18 2010-12-17 Giminingumo chromatografijos metodas
LTEP10790452.6T LT2513134T (lt) 2009-12-18 2010-12-17 Praplovimo tirpalas ir afininės chromatografijos metodas

Family Applications After (1)

Application Number Title Priority Date Filing Date
LTEP10790452.6T LT2513134T (lt) 2009-12-18 2010-12-17 Praplovimo tirpalas ir afininės chromatografijos metodas

Country Status (18)

Country Link
US (3) US9505803B2 (lt)
EP (2) EP2513134B1 (lt)
JP (2) JP5909450B2 (lt)
KR (1) KR101858266B1 (lt)
CN (1) CN102725304B (lt)
AU (1) AU2010332778B2 (lt)
BR (1) BR112012014937B1 (lt)
CA (1) CA2784278C (lt)
DK (2) DK3272764T3 (lt)
ES (1) ES2651065T3 (lt)
IL (1) IL220164B (lt)
LT (2) LT3272764T (lt)
MX (1) MX2012007103A (lt)
PL (1) PL2513134T3 (lt)
PT (2) PT2513134T (lt)
RU (1) RU2564569C2 (lt)
SG (2) SG181771A1 (lt)
WO (1) WO2011073389A1 (lt)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW201516149A (zh) 2006-09-13 2015-05-01 Abbvie Inc 細胞培養改良
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
CN104974251A (zh) 2008-10-20 2015-10-14 Abbvie公司 在抗体纯化过程中的病毒灭活
RU2520838C2 (ru) 2008-10-20 2014-06-27 Эббви Инк Выделение и очистка антител с использованием аффинной хроматографии на основе белка а
JP5909450B2 (ja) 2009-12-18 2016-04-26 ノバルティス アーゲー 洗浄溶液及びアフィニティークロマトグラフィーの方法
WO2011089212A1 (de) * 2010-01-22 2011-07-28 Boehringer Ingelheim International Gmbh Chromatographisches verfahren zur aufreinigung von fc enthaltenden proteinen
PL2714714T3 (pl) * 2011-06-01 2018-11-30 Novartis Ag Roztwór do przemywania i sposób chromatografii powinowactwa
ES2682081T3 (es) 2011-10-11 2018-09-18 F. Hoffmann-La Roche Ag Ensamblaje mejorado de anticuerpos biespecíficos
AU2014265624B2 (en) * 2013-05-15 2019-09-12 Medimmune Limited Purification of recombinantly produced polypeptides
US20150093800A1 (en) * 2013-09-05 2015-04-02 Genentech, Inc. Method for chromatography reuse
WO2015103545A1 (en) 2014-01-03 2015-07-09 Bio-Rad Laboratories, Inc. Removal of impurities from protein a eluates
US11566082B2 (en) 2014-11-17 2023-01-31 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
EP4194071A1 (en) 2015-03-13 2023-06-14 Bristol-Myers Squibb Company Use of alkaline washes during chromatography to remove impurities
JP6968055B2 (ja) 2015-08-21 2021-11-17 ジェネンテック, インコーポレイテッド アフィニティークロマトグラフィーにおける宿主細胞タンパク質の低減方法
US10654887B2 (en) 2016-05-11 2020-05-19 Ge Healthcare Bio-Process R&D Ab Separation matrix
ES2874974T3 (es) 2016-05-11 2021-11-05 Cytiva Bioprocess R & D Ab Matriz de separación
JP7106187B2 (ja) 2016-05-11 2022-07-26 サイティバ・バイオプロセス・アールアンドディ・アクチボラグ 分離マトリックスを保存する方法
US10703774B2 (en) 2016-09-30 2020-07-07 Ge Healthcare Bioprocess R&D Ab Separation method
US11753438B2 (en) 2016-05-11 2023-09-12 Cytiva Bioprocess R&D Ab Method of cleaning and/or sanitizing a separation matrix
US10889615B2 (en) 2016-05-11 2021-01-12 Cytiva Bioprocess R&D Ab Mutated immunoglobulin-binding polypeptides
US10730908B2 (en) 2016-05-11 2020-08-04 Ge Healthcare Bioprocess R&D Ab Separation method
WO2018022628A1 (en) * 2016-07-25 2018-02-01 Cephalon, Inc. Affinity chromatography wash buffer
EP3668985B1 (en) 2017-08-17 2021-06-16 Just-Evotec Biologics, Inc. Method of purifying glycosylated protein from host cell galectins and other contaminants
CN107793469B (zh) * 2017-10-16 2021-07-30 上海药明生物技术有限公司 一种去除宿主细胞蛋白含量的亲和纯化工艺
JP2021506925A (ja) * 2017-12-21 2021-02-22 ジェンザイム・コーポレーション プロテインaクロマトグラフィー中の不純物の除去を促進する方法
WO2019183334A1 (en) 2018-03-21 2019-09-26 Waters Technologies Corporation Non-antibody high-affinity-based sample preparation, sorbents, devices and methods
BR112020019882A2 (pt) 2018-04-02 2021-01-05 Amgen Inc. Composições de erenumabe e seus usos
WO2021072005A1 (en) * 2019-10-08 2021-04-15 North Carolina State University Immunoglobulin purification peptides and their use
CA3176109A1 (en) * 2020-03-27 2021-09-30 Haemalogix Pty Ltd Composition and method
EP4143203A1 (en) * 2020-04-27 2023-03-08 Alexion Pharmaceuticals, Inc. Protein a chromatography purification of an antibody
CN112827217A (zh) * 2020-12-29 2021-05-25 苏州良辰生物医药科技有限公司 一种层析柱清洗液及其应用

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4704366A (en) 1984-06-22 1987-11-03 Bio-Rad Laboratories, Inc. Process for binding IgG to protein A
US4857320A (en) * 1987-02-19 1989-08-15 Monsanto Company Method of enhancing the solubility of tissue plasminogen activator
JPH01238534A (ja) * 1988-03-17 1989-09-22 Mitsui Toatsu Chem Inc エンドトキシンの除去方法
US5429746A (en) 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
DK1864999T3 (da) 1996-11-27 2009-06-29 Genentech Inc Affinitetsoprensning af polypeptid på protein A-matrix
US6489447B1 (en) 1998-05-06 2002-12-03 Genentech, Inc. Protein purification
ATE274522T1 (de) 1998-06-01 2004-09-15 Genentech Inc Abtrennung von antikörper-monomeren von deren multimeren mittels ionaustausch-chromatographie
EP3088412B1 (en) 2001-03-09 2021-05-05 Chugai Seiyaku Kabushiki Kaisha Protein purification method
US7223848B2 (en) 2001-06-05 2007-05-29 Genetics Institute, Llc Methods for purifying Fc-containing proteins
WO2003066662A2 (en) 2002-02-05 2003-08-14 Genentech, Inc. Protein purification
SI1561756T1 (sl) 2002-09-11 2016-02-29 Chugai Seiyaku Kabushiki Kaisha Postopek čiščenja proteinov
CA2503284A1 (en) * 2002-10-24 2004-05-06 Enos Pharmaceuticals, Inc. Sustained release l-arginine formulations and methods of manufacture and use
WO2004056308A2 (en) * 2002-11-26 2004-07-08 Protein Design Labs, Inc. CHIMERIC AND HUMANIZED ANTIBODIES TO α5β1 INTEGRIN THAT MODULATE ANGIOGENESIS
SI1599222T1 (sl) * 2003-01-08 2009-08-31 Novartis Vaccines & Diagnostic Stabilizirani vodni sestavki, ki obsegajo inhibitor poti tkivnega faktorja (TFPI) ali varianto inhibitorja poti tkivnega faktorja
GB0304576D0 (en) 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
EP1601697B1 (en) 2003-02-28 2007-05-30 Lonza Biologics plc Antibody purification by Protein A and ion exchange chromatography
US9469672B2 (en) 2003-10-27 2016-10-18 Wyeth Llc Removal of high molecular weight aggregates using hydroxyapatite chromatography
US8084032B2 (en) 2004-01-21 2011-12-27 Ajinomoto Co., Inc. Purification method which prevents denaturation of an antibody
EP1698637B1 (en) 2005-03-03 2008-10-15 Ajinomoto Co., Inc. A method for improving recovery yield in protein purification with gel filtration chromatography using arginine
PL1869065T3 (pl) * 2005-03-11 2020-09-21 Wyeth Llc Sposób prowadzenia chromatografii podziałowej ze słabym wiązaniem
ES2662042T3 (es) 2006-01-06 2018-04-05 Emd Millipore Corporation Matrices cromatográficas de afinidad y métodos de fabricación y utilización de las mismas
WO2007109163A2 (en) 2006-03-16 2007-09-27 Amgen Inc Wash buffer and method of using
KR20080111487A (ko) 2006-03-20 2008-12-23 메다렉스, 인코포레이티드 단백질 정제 방법
JP2009539767A (ja) * 2006-06-02 2009-11-19 ワイス 精製および治療方法のためのTGF−βスーパーファミリータンパク質およびペプチドの使用
US7754689B2 (en) * 2006-06-02 2010-07-13 Wyeth Llc Finger-1 peptide analogs of the TGF-β superfamily
PL2061803T5 (pl) 2006-08-28 2023-03-27 Ares Trading S.A. Proces oczyszczania białek zawierających fc
US7714111B2 (en) * 2006-09-08 2010-05-11 Wyeth Llc Arginine derivative wash in protein purification using affinity chromatography
AU2008206923A1 (en) 2007-01-17 2008-07-24 Merck Serono S.A. Process for the purification of Fc-containing proteins
JP5064558B2 (ja) 2007-06-01 2012-10-31 エフ.ホフマン−ラ ロシュ アーゲー 免疫グロブリン精製
JP2011523408A (ja) 2008-05-15 2011-08-11 ノボ・ノルデイスク・エー/エス 抗体精製方法
CN102171237A (zh) 2008-08-14 2011-08-31 默沙东公司 使用蛋白a亲和色谱法纯化抗体的方法
JP5909450B2 (ja) * 2009-12-18 2016-04-26 ノバルティス アーゲー 洗浄溶液及びアフィニティークロマトグラフィーの方法
PL2714714T3 (pl) 2011-06-01 2018-11-30 Novartis Ag Roztwór do przemywania i sposób chromatografii powinowactwa

Also Published As

Publication number Publication date
CA2784278A1 (en) 2011-06-23
SG181771A1 (en) 2012-07-30
CN102725304B (zh) 2015-12-09
CN102725304A (zh) 2012-10-10
PT2513134T (pt) 2017-12-14
LT2513134T (lt) 2017-11-27
KR20120109506A (ko) 2012-10-08
RU2564569C2 (ru) 2015-10-10
BR112012014937B1 (pt) 2021-01-19
US20120283416A1 (en) 2012-11-08
IL220164B (en) 2019-02-28
EP3272764B1 (en) 2024-02-07
JP2013514073A (ja) 2013-04-25
SG10201408384PA (en) 2015-01-29
DK3272764T3 (da) 2024-05-06
US20190233469A1 (en) 2019-08-01
KR101858266B1 (ko) 2018-05-15
EP2513134B1 (en) 2017-09-06
PL2513134T3 (pl) 2018-02-28
AU2010332778B2 (en) 2015-03-19
CA2784278C (en) 2019-02-26
EP2513134A1 (en) 2012-10-24
DK2513134T3 (en) 2017-12-18
US20170044211A1 (en) 2017-02-16
AU2010332778A1 (en) 2012-07-19
WO2011073389A1 (en) 2011-06-23
PT3272764T (pt) 2024-04-24
MX2012007103A (es) 2012-07-17
ES2651065T3 (es) 2018-01-24
JP2016128495A (ja) 2016-07-14
IL220164A0 (en) 2012-07-31
US9505803B2 (en) 2016-11-29
JP5909450B2 (ja) 2016-04-26
BR112012014937A2 (pt) 2016-03-08
EP3272764A1 (en) 2018-01-24
RU2012130151A (ru) 2014-01-27

Similar Documents

Publication Publication Date Title
LT3272764T (lt) Giminingumo chromatografijos metodas
EP2160227A4 (en) chromatographic methods
EP2389386A4 (en) affinity chromatography
ZA201202299B (en) Method for decreasing immunigenicity
PL2464655T3 (pl) Procesy chromatograficzne
GB0905140D0 (en) Method
GB0902476D0 (en) Method
GB0910707D0 (en) Method
PT2096102E (pt) Processo para a produção de metileno-difenil-diisocianatos
EP2339339A4 (en) CHARGE FOR AFFINITY CHROMATOGRAPHY
EP2562178A4 (en) FILLING AGENT FOR AFFINITY CHROMATOGRAPHY
IL202942A (en) Chromatographic methods
EP2270480A4 (en) ANALYTICAL METHOD
ZA201005980B (en) Assembly method
EP2629091A4 (en) CHROMATOGRAPHY RELEASE AGENT
GB0901444D0 (en) Method
EP2590722A4 (en) TIMING PROCEDURE
GB0903316D0 (en) Method
GB0908770D0 (en) Method
ZA201203155B (en) Method for isolating methylglycinenitrile-n,n-diacetonitrile
GB0902034D0 (en) Method
GB0900560D0 (en) Method
GB0904946D0 (en) Method
HK1169380A1 (en) Method for isolating cimiracemate
EP2229580A4 (en) METHOD FOR APPLICATION OF SAMPLES