PL318440A1 - (-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor - Google Patents

(-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor

Info

Publication number
PL318440A1
PL318440A1 PL96318440A PL31844096A PL318440A1 PL 318440 A1 PL318440 A1 PL 318440A1 PL 96318440 A PL96318440 A PL 96318440A PL 31844096 A PL31844096 A PL 31844096A PL 318440 A1 PL318440 A1 PL 318440A1
Authority
PL
Poland
Prior art keywords
piperazin
phenoxy
pyridyl
methyl
butyric acid
Prior art date
Application number
PL96318440A
Other languages
English (en)
Inventor
Stuart Dennett Mills
Original Assignee
Zeneca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/457,538 external-priority patent/US5652242A/en
Priority claimed from GBGB9518188.9A external-priority patent/GB9518188D0/en
Application filed by Zeneca Ltd filed Critical Zeneca Ltd
Publication of PL318440A1 publication Critical patent/PL318440A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
PL96318440A 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor PL318440A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/457,538 US5652242A (en) 1993-03-29 1995-06-01 Heterocyclic derivatives
GBGB9518188.9A GB9518188D0 (en) 1995-09-07 1995-09-07 Optically active derivative

Publications (1)

Publication Number Publication Date
PL318440A1 true PL318440A1 (en) 1997-06-09

Family

ID=26307696

Family Applications (1)

Application Number Title Priority Date Filing Date
PL96318440A PL318440A1 (en) 1995-06-01 1996-05-28 (-)-(3r)-3-methyl-4-{4-[4-pyridyl)piperazin-1-yl]phenoxy}butyric acid as cellular adhesion inhibitor

Country Status (31)

Country Link
EP (1) EP0796247A1 (ja)
JP (1) JP2885941B2 (ja)
KR (1) KR100245957B1 (ja)
AT (1) AT406675B (ja)
AU (1) AU710105B2 (ja)
BE (1) BE1009520A5 (ja)
BR (1) BR9606409A (ja)
CA (1) CA2194397A1 (ja)
CH (1) CH691808A5 (ja)
CZ (1) CZ26997A3 (ja)
DE (1) DE19680509T1 (ja)
DK (1) DK10697A (ja)
ES (1) ES2137886B1 (ja)
FI (1) FI970393A0 (ja)
GB (1) GB2304340B (ja)
GR (1) GR1002702B (ja)
HU (1) HUP9700274A3 (ja)
IE (1) IE960405A1 (ja)
IL (1) IL118477A0 (ja)
IT (1) IT1290839B1 (ja)
LU (1) LU90008B1 (ja)
MC (1) MC2418A1 (ja)
MX (1) MX9700379A (ja)
NL (1) NL1003243C2 (ja)
NO (1) NO307460B1 (ja)
NZ (1) NZ308597A (ja)
PL (1) PL318440A1 (ja)
SE (1) SE510812C2 (ja)
SK (1) SK13097A3 (ja)
TR (1) TR199700020T1 (ja)
WO (1) WO1996038416A1 (ja)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0100158A3 (en) * 1982-07-28 1985-03-27 The Upjohn Company (3-pyridinyl)heteroalkarylalkanols, alkanoic acids and esters
GB8609630D0 (en) * 1986-04-19 1986-05-21 Pfizer Ltd Anti-arrhythmia agents
PL310889A1 (en) * 1993-03-29 1996-01-08 Zeneca Ltd Heterocyclic derivatives as inhibitors of thrombocytes aggregation
NZ262942A (en) * 1993-03-29 1997-07-27 Zeneca Ltd Pyridyl substituted piperazine and various other derivatives of azaheteroaryl substituted piperazines; pharmaceutical compositions

Also Published As

Publication number Publication date
IL118477A0 (en) 1996-09-12
AT406675B (de) 2000-07-25
FI970393A (fi) 1997-01-30
ATA900596A (de) 1999-12-15
ES2137886A1 (es) 1999-12-16
HU9700274D0 (en) 1997-04-28
JP2885941B2 (ja) 1999-04-26
DE19680509T1 (de) 1997-12-04
KR970704689A (ko) 1997-09-06
SK13097A3 (en) 1997-08-06
ES2137886B1 (es) 2000-08-16
TR199700020T1 (tr) 1997-04-22
ITMI961113A0 (it) 1996-05-31
FI970393A0 (fi) 1997-01-30
LU90008B1 (fr) 1997-04-16
DK10697A (da) 1997-04-01
NO970437D0 (no) 1997-01-31
CA2194397A1 (en) 1996-12-05
NL1003243C2 (nl) 1996-12-04
ITMI961113A1 (it) 1997-12-01
CH691808A5 (de) 2001-10-31
SE9700203L (sv) 1997-01-24
MX9700379A (es) 1997-04-30
HUP9700274A3 (en) 2000-02-28
CZ26997A3 (en) 1997-08-13
KR100245957B1 (ko) 2000-04-01
HUP9700274A2 (hu) 1999-06-28
AU5827296A (en) 1996-12-18
GB9627127D0 (en) 1997-02-19
SE510812C2 (sv) 1999-06-28
BR9606409A (pt) 1997-09-30
IT1290839B1 (it) 1998-12-14
JPH09512836A (ja) 1997-12-22
MC2418A1 (fr) 1997-05-23
NO970437L (no) 1997-02-20
SE9700203D0 (sv) 1997-01-24
WO1996038416A1 (en) 1996-12-05
GR1002702B (el) 1997-05-22
NZ308597A (en) 1998-11-25
IE960405A1 (en) 1996-12-11
EP0796247A1 (en) 1997-09-24
NO307460B1 (no) 2000-04-10
GB2304340A (en) 1997-03-19
AU710105B2 (en) 1999-09-16
GB2304340B (en) 1998-07-29
BE1009520A5 (fr) 1997-04-01

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