PL142909B1 - Method of obtaining novel derivatives of thiazolidine - Google Patents

Method of obtaining novel derivatives of thiazolidine Download PDF

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Publication number
PL142909B1
PL142909B1 PL1984252129A PL25212984A PL142909B1 PL 142909 B1 PL142909 B1 PL 142909B1 PL 1984252129 A PL1984252129 A PL 1984252129A PL 25212984 A PL25212984 A PL 25212984A PL 142909 B1 PL142909 B1 PL 142909B1
Authority
PL
Poland
Prior art keywords
ppm
compound
indomethacin
thiazolidine
formula
Prior art date
Application number
PL1984252129A
Other languages
English (en)
Polish (pl)
Other versions
PL252129A1 (en
Inventor
Elemer Ezer
Kalman Harsanyi
Gyorgy Domany
Laszlo Szporny
Judit Matuz
Bela Hegedus
Katalin Pallagi
Istvan Szabadkai
Peter Tetenyi
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of PL252129A1 publication Critical patent/PL252129A1/xx
Publication of PL142909B1 publication Critical patent/PL142909B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/18—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
PL1984252129A 1983-03-16 1984-03-13 Method of obtaining novel derivatives of thiazolidine PL142909B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU83888A HU188852B (en) 1983-03-16 1983-03-16 Process for producing thiazolidine derivatives active against gastric ulcer and intestinal ulcer

Publications (2)

Publication Number Publication Date
PL252129A1 PL252129A1 (en) 1985-11-19
PL142909B1 true PL142909B1 (en) 1987-12-31

Family

ID=10951891

Family Applications (2)

Application Number Title Priority Date Filing Date
PL1984252129A PL142909B1 (en) 1983-03-16 1984-03-13 Method of obtaining novel derivatives of thiazolidine
PL1984246683A PL142749B1 (en) 1983-03-16 1984-03-15 Method of obtaining novel thiazolydine derivatives

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL1984246683A PL142749B1 (en) 1983-03-16 1984-03-15 Method of obtaining novel thiazolydine derivatives

Country Status (32)

Country Link
US (1) US4616025A (en:Method)
JP (1) JPS59196877A (en:Method)
KR (1) KR840008001A (en:Method)
AT (1) AT383596B (en:Method)
AU (1) AU559753B2 (en:Method)
BE (1) BE899132A (en:Method)
CA (1) CA1273933A (en:Method)
CH (1) CH660592A5 (en:Method)
CS (1) CS241074B2 (en:Method)
DD (1) DD216929A5 (en:Method)
DE (1) DE3409801A1 (en:Method)
DK (1) DK143284A (en:Method)
ES (2) ES530738A0 (en:Method)
FI (1) FI79843C (en:Method)
FR (1) FR2542740B1 (en:Method)
GB (1) GB2140412B (en:Method)
GR (1) GR81883B (en:Method)
HU (1) HU188852B (en:Method)
IE (1) IE57101B1 (en:Method)
IL (1) IL71249A (en:Method)
IN (1) IN157738B (en:Method)
IT (1) IT1196048B (en:Method)
LU (1) LU85248A1 (en:Method)
NL (1) NL8400817A (en:Method)
NO (1) NO162858C (en:Method)
NZ (1) NZ207516A (en:Method)
PL (2) PL142909B1 (en:Method)
PT (1) PT78260B (en:Method)
SE (1) SE455945B (en:Method)
SU (2) SU1240355A3 (en:Method)
YU (1) YU47384A (en:Method)
ZA (1) ZA841938B (en:Method)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6051184A (ja) * 1983-08-30 1985-03-22 Fujimoto Seiyaku Kk Ν−シアノイミノチアゾリジン誘導体およびその製造法
JPH0730070B2 (ja) * 1985-10-03 1995-04-05 日本バイエルアグロケム株式会社 新規複素環式化合物
EP0192060B1 (de) * 1985-02-04 1991-09-18 Nihon Bayer Agrochem K.K. Heterocyclische Verbindungen
JPH0649699B2 (ja) * 1985-02-04 1994-06-29 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
US5204360A (en) * 1985-02-04 1993-04-20 Nihon Bayer Agrochem K.K. Heterocyclic compounds
US5001138B1 (en) * 1985-02-04 1998-01-20 Bayer Agrochem Kk Heterocyclic compounds
JPH066585B2 (ja) * 1985-02-04 1994-01-26 日本バイエルアグロケム株式会社 ニトロメチレン誘導体、その製法及び殺虫剤
USRE39130E1 (en) 1986-03-07 2006-06-13 Bayer Cropscience K.K. Heterocyclic compounds
JPH0717621B2 (ja) * 1986-03-07 1995-03-01 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
JP2607369B2 (ja) * 1987-02-20 1997-05-07 興和株式会社 新規な複素環化合物
DE69033246T2 (de) * 1989-06-21 1999-12-02 Trustees Of The University Of Pennsylvania, Philadelphia Behandlung und Regulierung der Augenentwicklung mit cholinergischen Agonisten
US5122522A (en) * 1989-06-21 1992-06-16 The Trustees Of The University Of Pennsylvania Treatment and control of ocular development
HU207047B (en) * 1989-11-07 1993-03-01 Richter Gedeon Vegyeszet Process for producing new pyridine derivatives and pharmaceutical copositions comprising same
US5240918A (en) * 1992-03-24 1993-08-31 Egis Gyogyszergyar 2-(substituted imino)-thiazolidines and process for the preparation thereof
JP2721805B2 (ja) * 1994-07-22 1998-03-04 日本バイエルアグロケム株式会社 新規ヘテロ環式化合物
DE4427569A1 (de) * 1994-08-04 1996-02-08 Bayer Ag Verfahren zur Herstellung von Cyanimino-1,3-thiazolidin
DE4427539A1 (de) * 1994-08-04 1996-02-08 Sueddeutsche Kalkstickstoff Verfahren zur Herstellung von 2-Cyaniminothiazolidin
DE19904310A1 (de) * 1999-01-28 2000-08-03 Bayer Ag Verfahren zur Herstellung heterocyclischer Verbindungen
CN1198803C (zh) * 1999-03-05 2005-04-27 第一三得利制药株式会社 具有激活烟碱性乙酰胆碱α4β2受体作用的杂环化合物
BR0107648B1 (pt) * 2000-01-19 2013-10-22 Processo para produção de compostos heterocíclicos
HUP0304071A2 (hu) * 2001-05-25 2004-04-28 Valley Forge Pharmaceuticals Pirenzepine-tartalmú szemészeti gélkészítmény és eljárás az előállítására
PT1567112E (pt) * 2002-11-22 2009-01-08 Smithkline Beecham Corp Novos compostos químicos
AU2004228069B2 (en) * 2003-04-07 2011-09-08 Cortical Pty Ltd Novel methods for the treatment of inflammatory diseases
RU2535674C2 (ru) * 2008-07-01 2014-12-20 Мейдзи Сейка Фарма Ко.,Лтд. Новые иминопроизводные, способы их получения и инсектициды, содержащие такие иминопроизводные
MX357595B (es) * 2011-09-02 2018-07-16 Bayer Ip Gmbh Procedimiento para preparar [3-[(6-cloro-3-piridinil)metil]-2-tiaz olidiniliden]cianamida.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3264316A (en) * 1963-09-18 1966-08-02 Res Lab Dr C Janssen N V Certain 2-acylimino-3-substitutedthiazoline-4 compounds
DE2205745A1 (de) * 1972-02-08 1973-08-23 Thomae Gmbh Dr K Neue durch den n-cyaniminorest substituierten heterocyclen und verfahren zu ihrer herstellung
US4006156A (en) * 1975-06-27 1977-02-01 Shell Oil Company 3-Alkyl-2-(nitromethylene) thiazolidine
DK173777A (da) * 1976-05-03 1977-11-04 Merck & Co Inc Fremgangsmade til fremstilling af derivater af 2-iminothiazolidiner og thiazoliner
JPS57171986A (en) * 1981-04-14 1982-10-22 Taiho Yakuhin Kogyo Kk Heterocylic ring compound containing sulfur
JPS5823682A (ja) * 1981-08-03 1983-02-12 Santen Pharmaceut Co Ltd 複素五員環化合物
DE3133918A1 (de) * 1981-08-27 1983-03-17 Bayer Ag, 5090 Leverkusen 2-arylhydrazino-2-thiazoline, acylderivate derselben, 2-arylazo-2-thiazoline, herstellungsverfahren und ihre verwendung zur bekaempfung von ekto- und endoparasiten
JPS58222886A (ja) * 1982-06-19 1983-12-24 Ricoh Co Ltd 感熱記録シ−ト
JPS5933267A (ja) * 1982-08-19 1984-02-23 Fujimoto Seiyaku Kk グアニジン誘導体およびその製造法

Also Published As

Publication number Publication date
ES8604179A1 (es) 1986-01-16
ZA841938B (en) 1985-05-29
PT78260B (en) 1986-04-30
IT8420057A0 (it) 1984-03-15
ES8601170A1 (es) 1985-11-01
PL246683A1 (en) 1985-07-16
KR840008001A (ko) 1984-12-12
NL8400817A (nl) 1984-10-16
IL71249A (en) 1987-02-27
DE3409801A1 (de) 1984-09-20
NO162858B (no) 1989-11-20
PT78260A (en) 1984-04-01
CA1273933A (en) 1990-09-11
DD216929A5 (de) 1985-01-02
DK143284D0 (da) 1984-02-29
CH660592A5 (de) 1987-05-15
FI79843C (fi) 1990-03-12
IE57101B1 (en) 1992-04-22
DK143284A (da) 1984-09-17
LU85248A1 (fr) 1985-10-14
US4616025A (en) 1986-10-07
SU1240355A3 (ru) 1986-06-23
GB8406790D0 (en) 1984-04-18
SE8401463L (sv) 1984-09-17
GR81883B (en:Method) 1984-12-12
NZ207516A (en) 1986-06-11
BE899132A (fr) 1984-09-12
IL71249A0 (en) 1984-06-29
CS188584A2 (en) 1985-06-13
AU2583384A (en) 1984-09-20
GB2140412A (en) 1984-11-28
ES544286A0 (es) 1986-01-16
PL142749B1 (en) 1987-11-30
FR2542740B1 (fr) 1987-02-20
ES530738A0 (es) 1985-11-01
CS241074B2 (en) 1986-03-13
FI841066L (fi) 1984-09-17
IN157738B (en:Method) 1986-05-31
AU559753B2 (en) 1987-03-19
YU47384A (en:Method) 1986-10-31
IT1196048B (it) 1988-11-10
FR2542740A1 (fr) 1984-09-21
SE455945B (sv) 1988-08-22
FI79843B (fi) 1989-11-30
NO841002L (no) 1984-09-17
PL252129A1 (en) 1985-11-19
GB2140412B (en) 1987-02-11
ATA88284A (de) 1986-12-15
AT383596B (de) 1987-07-27
IE840655L (en) 1984-09-16
SE8401463D0 (sv) 1984-03-15
JPS59196877A (ja) 1984-11-08
FI841066A0 (fi) 1984-03-16
SU1240356A3 (ru) 1986-06-23
NO162858C (no) 1990-02-28
HU188852B (en) 1986-05-28

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