PE38397A1 - Terapia combinada para infeccion por vih - Google Patents

Terapia combinada para infeccion por vih

Info

Publication number
PE38397A1
PE38397A1 PE1996000073A PE00007396A PE38397A1 PE 38397 A1 PE38397 A1 PE 38397A1 PE 1996000073 A PE1996000073 A PE 1996000073A PE 00007396 A PE00007396 A PE 00007396A PE 38397 A1 PE38397 A1 PE 38397A1
Authority
PE
Peru
Prior art keywords
hiv
inhibitor
hiv infection
combined therapy
aids
Prior art date
Application number
PE1996000073A
Other languages
English (en)
Inventor
A Chodakewitz Jeffrey
A Emini Emilio
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of PE38397A1 publication Critical patent/PE38397A1/es

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE REFIERE A LA COMBINACION DE COMPUESTOS PARA EVITAR EL DESARROLLO DE RESISTENCIA EN EL TRATAMIENTO DEL SIDA O CRS(COMPLEJO RELACIONADO AL SIDA), QUE COMPRENDE: (A+B) o (A+B+C), EN DONDE (A) ES UN INHIBIDOR DE LA PROTEASA DE VIH, CONOCIDO COMO J, DE FORMULA N-(2(R)-HIDROXI-1(S)-INDANIL)-2(R)-FENILMETIL-4-(S), HIDROXI-5-(1-(4-(3-(PIRIDILMETIL)-2(S)-N`-(T-BUTIL-CARBOXAMIDO)-PIPERAZINIL))-PENTANOAMIDA, O SUS SALES FARMACEUTICAMENTE ACEPTABLES; (B) ES UN INHIBIDOR NUCLEOSIDO DE LA TRANSCRIPTASA DE VIH, CONOCIDO COMO 3TC, DE FORMULA I; (C) ES UN INHIBIDOR NUCLEOSIDO DE LA TRANSCRIPTASA DE VIH, SELECCIONADO ENTRE AZT, ddI O ddC. ESTOS COMPUESTOS ACTUAN INHIBIENDO LA PROTEASA Y LA TRANSCRIPTASA DEL VIRUS VIH, DE TAL MANERA QUE RESULTEN VIRUS INMADUROS, DE CARACTER NO INFECCIOSOS
PE1996000073A 1995-02-01 1996-01-31 Terapia combinada para infeccion por vih PE38397A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/382,113 US6689761B1 (en) 1995-02-01 1995-02-01 Combination therapy for HIV infection

Publications (1)

Publication Number Publication Date
PE38397A1 true PE38397A1 (es) 1997-10-09

Family

ID=23507574

Family Applications (1)

Application Number Title Priority Date Filing Date
PE1996000073A PE38397A1 (es) 1995-02-01 1996-01-31 Terapia combinada para infeccion por vih

Country Status (38)

Country Link
US (1) US6689761B1 (es)
EP (1) EP0806957B1 (es)
JP (1) JPH10513186A (es)
KR (1) KR19980701856A (es)
CN (1) CN1160081C (es)
AR (1) AR002957A1 (es)
AT (1) ATE243519T1 (es)
AU (1) AU711176B2 (es)
BR (1) BR9607714A (es)
CA (1) CA2211973A1 (es)
CO (1) CO4700430A1 (es)
CZ (1) CZ244497A3 (es)
DE (1) DE69628819T2 (es)
DK (1) DK0806957T3 (es)
DZ (1) DZ1988A1 (es)
EA (1) EA000437B1 (es)
EE (1) EE03514B1 (es)
ES (1) ES2200052T3 (es)
FI (1) FI973184A (es)
HK (1) HK1004659A1 (es)
HR (1) HRP960045B1 (es)
HU (1) HUP9800810A3 (es)
IL (1) IL116925A (es)
IS (1) IS1970B (es)
MX (1) MX9705916A (es)
MY (1) MY121604A (es)
NO (1) NO314568B1 (es)
NZ (1) NZ302153A (es)
PE (1) PE38397A1 (es)
PL (1) PL182742B1 (es)
PT (1) PT806957E (es)
SA (1) SA96160669B1 (es)
SK (1) SK103797A3 (es)
TR (1) TR199700735T1 (es)
TW (1) TW442291B (es)
WO (1) WO1996023509A1 (es)
YU (1) YU49417B (es)
ZA (1) ZA96722B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008539A1 (en) * 1996-08-26 1998-03-05 Chiron Corporation Postinfection human immunodeficiency virus (hiv) vaccination therapy
AU6761198A (en) * 1998-03-17 1999-10-11 Julianna Lisziwiewicz Anti-hiv combination comprising hydroxyurea, ddi, and a protease inhibitor
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
AU4219799A (en) * 1998-05-29 1999-12-13 University Of Florida Combination therapy for treatment of fiv infection
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性hivc型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
WO2003004620A2 (en) 2001-07-05 2003-01-16 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
CA2583195A1 (en) * 2004-11-19 2006-05-26 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and reverset
US7745455B2 (en) 2005-07-27 2010-06-29 Emil Toma Zalcitabine (ddC) boosted lamivudine (3TC) compositions for antiretroviral therapy
CA3047000A1 (en) * 2017-01-04 2018-07-12 Oyagen, Inc. Compounds, compositions, and methods for treating human immunodeficiency virus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5254539A (en) * 1985-08-26 1993-10-19 U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health Method of treating HIV with 2',3'-dideoxyinosine
US5028595A (en) * 1987-09-18 1991-07-02 Hoffmann-La Roche Inc. Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
IL100502A (en) 1991-01-03 1995-12-08 Iaf Biochem Int PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS
KR100311551B1 (ko) 1993-03-31 2001-12-28 폴락 돈나 엘. Aids 치료용 약제학적 배합물 중의 hiv 프로테아제 억제제
IL114208A0 (en) 1994-06-27 1995-10-31 Merck & Co Inc Combinations of compounds pharmaceutical compositions containing them and their use as hiv protease inhibitors

Also Published As

Publication number Publication date
IL116925A (en) 2000-07-26
SA96160669B1 (ar) 2006-07-30
FI973184A (fi) 1997-09-30
EP0806957A1 (en) 1997-11-19
HRP960045B1 (en) 2004-06-30
PL182742B1 (pl) 2002-02-28
JPH10513186A (ja) 1998-12-15
KR19980701856A (ko) 1998-06-25
CZ244497A3 (cs) 1998-01-14
CO4700430A1 (es) 1998-12-29
IS1970B (is) 2004-12-15
AU711176B2 (en) 1999-10-07
ES2200052T3 (es) 2004-03-01
BR9607714A (pt) 1998-01-13
FI973184A0 (fi) 1997-07-31
EE03514B1 (et) 2001-10-15
MX9705916A (es) 1997-10-31
NO314568B1 (no) 2003-04-14
HUP9800810A3 (en) 2001-05-28
CN1179722A (zh) 1998-04-22
DK0806957T3 (da) 2003-09-29
EA199700150A1 (ru) 1997-12-30
PT806957E (pt) 2003-10-31
EE9700165A (et) 1998-02-16
YU6396A (sh) 1999-06-15
NO973533L (no) 1997-10-01
TW442291B (en) 2001-06-23
ATE243519T1 (de) 2003-07-15
AU4774896A (en) 1996-08-21
DZ1988A1 (fr) 2002-07-20
HUP9800810A2 (hu) 1998-07-28
HRP960045A2 (en) 1997-10-31
CA2211973A1 (en) 1996-08-08
WO1996023509A1 (en) 1996-08-08
IL116925A0 (en) 1996-05-14
IS4533A (is) 1997-07-29
HK1004659A1 (en) 1998-12-04
MY121604A (en) 2006-02-28
NZ302153A (en) 1998-12-23
CN1160081C (zh) 2004-08-04
SK103797A3 (en) 1998-02-04
ZA96722B (en) 1996-08-26
DE69628819T2 (de) 2004-05-13
EP0806957B1 (en) 2003-06-25
YU49417B (sh) 2006-01-16
US6689761B1 (en) 2004-02-10
AR002957A1 (es) 1998-05-27
PL321660A1 (en) 1997-12-22
DE69628819D1 (de) 2003-07-31
EA000437B1 (ru) 1999-08-26
NO973533D0 (no) 1997-07-31
TR199700735T1 (xx) 1998-02-21

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FD Application declared void or lapsed