YU49417B - Terapijska kombinacija za hiv infekcije - Google Patents

Terapijska kombinacija za hiv infekcije

Info

Publication number
YU49417B
YU49417B YU6396A YU6396A YU49417B YU 49417 B YU49417 B YU 49417B YU 6396 A YU6396 A YU 6396A YU 6396 A YU6396 A YU 6396A YU 49417 B YU49417 B YU 49417B
Authority
YU
Yugoslavia
Prior art keywords
combination therapy
hiv infection
hydroxy
reverse transcriptase
hiv reverse
Prior art date
Application number
YU6396A
Other languages
English (en)
Other versions
YU6396A (sh
Inventor
Jeffrey A. Chodakewitz
Emilio A. Emini
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of YU6396A publication Critical patent/YU6396A/sh
Publication of YU49417B publication Critical patent/YU49417B/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Kombinacija jedinjenja naznačena time, što je čine (N-(2-(R)-hidroksi-1(S)-indanil)-2(R)-fenilmetil-4(S)-hidroksi-5-(1-(4-(3-piridilmetil)-2(S)-N'-(t-butilkarboksamido)-piperazinil))-pentamid (Jedinjenje J) i nukleozidni analog inhibitora HIV reverzne transkriptaze 3TC i nukleozidni inhibitor HIV reverzne transkriptaze AZT, ili njegova farmaceutski prihvatljiva so ili estar. Prijava sadrži još 1 nezavisni i 6 zavisnih patentnih zahteva.
YU6396A 1995-02-01 1996-02-01 Terapijska kombinacija za hiv infekcije YU49417B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/382,113 US6689761B1 (en) 1995-02-01 1995-02-01 Combination therapy for HIV infection

Publications (2)

Publication Number Publication Date
YU6396A YU6396A (sh) 1999-06-15
YU49417B true YU49417B (sh) 2006-01-16

Family

ID=23507574

Family Applications (1)

Application Number Title Priority Date Filing Date
YU6396A YU49417B (sh) 1995-02-01 1996-02-01 Terapijska kombinacija za hiv infekcije

Country Status (38)

Country Link
US (1) US6689761B1 (sh)
EP (1) EP0806957B1 (sh)
JP (1) JPH10513186A (sh)
KR (1) KR19980701856A (sh)
CN (1) CN1160081C (sh)
AR (1) AR002957A1 (sh)
AT (1) ATE243519T1 (sh)
AU (1) AU711176B2 (sh)
BR (1) BR9607714A (sh)
CA (1) CA2211973A1 (sh)
CO (1) CO4700430A1 (sh)
CZ (1) CZ244497A3 (sh)
DE (1) DE69628819T2 (sh)
DK (1) DK0806957T3 (sh)
DZ (1) DZ1988A1 (sh)
EA (1) EA000437B1 (sh)
EE (1) EE03514B1 (sh)
ES (1) ES2200052T3 (sh)
FI (1) FI973184A (sh)
HK (1) HK1004659A1 (sh)
HR (1) HRP960045B1 (sh)
HU (1) HUP9800810A3 (sh)
IL (1) IL116925A (sh)
IS (1) IS1970B (sh)
MX (1) MX9705916A (sh)
MY (1) MY121604A (sh)
NO (1) NO314568B1 (sh)
NZ (1) NZ302153A (sh)
PE (1) PE38397A1 (sh)
PL (1) PL182742B1 (sh)
PT (1) PT806957E (sh)
SA (1) SA96160669B1 (sh)
SK (1) SK103797A3 (sh)
TR (1) TR199700735T1 (sh)
TW (1) TW442291B (sh)
WO (1) WO1996023509A1 (sh)
YU (1) YU49417B (sh)
ZA (1) ZA96722B (sh)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008539A1 (en) * 1996-08-26 1998-03-05 Chiron Corporation Postinfection human immunodeficiency virus (hiv) vaccination therapy
AU6761198A (en) * 1998-03-17 1999-10-11 Julianna Lisziwiewicz Anti-hiv combination comprising hydroxyurea, ddi, and a protease inhibitor
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
AU4219799A (en) * 1998-05-29 1999-12-13 University Of Florida Combination therapy for treatment of fiv infection
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性ｈｉｖｃ型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
WO2003004620A2 (en) 2001-07-05 2003-01-16 Chiron, Corporation Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof
CA2583195A1 (en) * 2004-11-19 2006-05-26 Boehringer Ingelheim International Gmbh Method for treating hiv infection through co-administration of tipranavir and reverset
US7745455B2 (en) 2005-07-27 2010-06-29 Emil Toma Zalcitabine (ddC) boosted lamivudine (3TC) compositions for antiretroviral therapy
CA3047000A1 (en) * 2017-01-04 2018-07-12 Oyagen, Inc. Compounds, compositions, and methods for treating human immunodeficiency virus

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5254539A (en) * 1985-08-26 1993-10-19 U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health Method of treating HIV with 2',3'-dideoxyinosine
US5028595A (en) * 1987-09-18 1991-07-02 Hoffmann-La Roche Inc. Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
IL100502A (en) 1991-01-03 1995-12-08 Iaf Biochem Int PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS
KR100311551B1 (ko) 1993-03-31 2001-12-28 폴락 돈나 엘. Aids 치료용 약제학적 배합물 중의 hiv 프로테아제 억제제
IL114208A0 (en) 1994-06-27 1995-10-31 Merck & Co Inc Combinations of compounds pharmaceutical compositions containing them and their use as hiv protease inhibitors

Also Published As

Publication number Publication date
IL116925A (en) 2000-07-26
SA96160669B1 (ar) 2006-07-30
FI973184A (fi) 1997-09-30
PE38397A1 (es) 1997-10-09
EP0806957A1 (en) 1997-11-19
HRP960045B1 (en) 2004-06-30
PL182742B1 (pl) 2002-02-28
JPH10513186A (ja) 1998-12-15
KR19980701856A (ko) 1998-06-25
CZ244497A3 (cs) 1998-01-14
CO4700430A1 (es) 1998-12-29
IS1970B (is) 2004-12-15
AU711176B2 (en) 1999-10-07
ES2200052T3 (es) 2004-03-01
BR9607714A (pt) 1998-01-13
FI973184A0 (fi) 1997-07-31
EE03514B1 (et) 2001-10-15
MX9705916A (es) 1997-10-31
NO314568B1 (no) 2003-04-14
HUP9800810A3 (en) 2001-05-28
CN1179722A (zh) 1998-04-22
DK0806957T3 (da) 2003-09-29
EA199700150A1 (ru) 1997-12-30
PT806957E (pt) 2003-10-31
EE9700165A (et) 1998-02-16
YU6396A (sh) 1999-06-15
NO973533L (no) 1997-10-01
TW442291B (en) 2001-06-23
ATE243519T1 (de) 2003-07-15
AU4774896A (en) 1996-08-21
DZ1988A1 (fr) 2002-07-20
HUP9800810A2 (hu) 1998-07-28
HRP960045A2 (en) 1997-10-31
CA2211973A1 (en) 1996-08-08
WO1996023509A1 (en) 1996-08-08
IL116925A0 (en) 1996-05-14
IS4533A (is) 1997-07-29
HK1004659A1 (en) 1998-12-04
MY121604A (en) 2006-02-28
NZ302153A (en) 1998-12-23
CN1160081C (zh) 2004-08-04
SK103797A3 (en) 1998-02-04
ZA96722B (en) 1996-08-26
DE69628819T2 (de) 2004-05-13
EP0806957B1 (en) 2003-06-25
US6689761B1 (en) 2004-02-10
AR002957A1 (es) 1998-05-27
PL321660A1 (en) 1997-12-22
DE69628819D1 (de) 2003-07-31
EA000437B1 (ru) 1999-08-26
NO973533D0 (no) 1997-07-31
TR199700735T1 (xx) 1998-02-21

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