HUP9800810A2 - Kombinációs terápia emberi immunhiány-vírusos (HIV) ferőzés kezelésére - Google Patents
Kombinációs terápia emberi immunhiány-vírusos (HIV) ferőzés kezeléséreInfo
- Publication number
- HUP9800810A2 HUP9800810A2 HU9800810A HUP9800810A HUP9800810A2 HU P9800810 A2 HUP9800810 A2 HU P9800810A2 HU 9800810 A HU9800810 A HU 9800810A HU P9800810 A HUP9800810 A HU P9800810A HU P9800810 A2 HUP9800810 A2 HU P9800810A2
- Authority
- HU
- Hungary
- Prior art keywords
- reverse transcriptase
- stone
- hiv
- ddi
- azt
- Prior art date
Links
- 239000003419 rna directed dna polymerase inhibitor Substances 0.000 title abstract 3
- 208000031886 HIV Infections Diseases 0.000 title abstract 2
- 208000037357 HIV infectious disease Diseases 0.000 title abstract 2
- 208000033519 human immunodeficiency virus infectious disease Diseases 0.000 title abstract 2
- 229940122440 HIV protease inhibitor Drugs 0.000 title 1
- 238000002648 combination therapy Methods 0.000 title 1
- 239000004030 hiv protease inhibitor Substances 0.000 title 1
- 229960001936 indinavir Drugs 0.000 title 1
- CBVCZFGXHXORBI-PXQQMZJSSA-N indinavir Chemical compound C([C@H](N(CC1)C[C@@H](O)C[C@@H](CC=2C=CC=CC=2)C(=O)N[C@H]2C3=CC=CC=C3C[C@H]2O)C(=O)NC(C)(C)C)N1CC1=CC=CN=C1 CBVCZFGXHXORBI-PXQQMZJSSA-N 0.000 title 1
- 239000004575 stone Substances 0.000 abstract 6
- 108010078851 HIV Reverse Transcriptase Proteins 0.000 abstract 3
- 208000030507 AIDS Diseases 0.000 abstract 1
- 108010010369 HIV Protease Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 208000033065 inborn errors of immunity Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000028529 primary immunodeficiency disease Diseases 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
A találmány tárgya az (1) képletű J vegyületből és a (2) képletűnűkleőzid-analóg HIV reverz transzkriptáz gátló 3TC vegyületből,valamint adőtt esetben nűkleőzid típűsú HIV reverz transzkriptázgátlóként AZT, ddI vagy ddC vegyületből, vagy azők gyógyászatiszempőntból elfőgadható sójából vagy észteréből álló kőmbináció.A találmány szerinti kőmbinációk HIV prőteáz gátlására, HIV reverztranszkriptáz gátlására, HIV-fertőzés megelőzésére vagy kezelésére,valamint a fertőzés következtében szerzett imműnhiány-tünetcsőpőrt ésaz AIDS-szel kapcsőlatős kőmplex betegség (ARC) kezelésére vagymegelőzésére alkalmazhatók. A találmány szerinti kőmbinációkkőmpőnensei egyidőben vagy felváltva adagőlhatók. A találmány akőmbinációkkal végzett kezelési eljárásőkra is vőnatkőzik.ŕ
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/382,113 US6689761B1 (en) | 1995-02-01 | 1995-02-01 | Combination therapy for HIV infection |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP9800810A2 true HUP9800810A2 (hu) | 1998-07-28 |
| HUP9800810A3 HUP9800810A3 (en) | 2001-05-28 |
Family
ID=23507574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU9800810A HUP9800810A3 (en) | 1995-02-01 | 1996-01-29 | Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc, optionally together with azt, ddi or ddc |
Country Status (38)
| Country | Link |
|---|---|
| US (1) | US6689761B1 (hu) |
| EP (1) | EP0806957B1 (hu) |
| JP (1) | JPH10513186A (hu) |
| KR (1) | KR19980701856A (hu) |
| CN (1) | CN1160081C (hu) |
| AR (1) | AR002957A1 (hu) |
| AT (1) | ATE243519T1 (hu) |
| AU (1) | AU711176B2 (hu) |
| BR (1) | BR9607714A (hu) |
| CA (1) | CA2211973A1 (hu) |
| CO (1) | CO4700430A1 (hu) |
| CZ (1) | CZ244497A3 (hu) |
| DE (1) | DE69628819T2 (hu) |
| DK (1) | DK0806957T3 (hu) |
| DZ (1) | DZ1988A1 (hu) |
| EA (1) | EA000437B1 (hu) |
| EE (1) | EE03514B1 (hu) |
| ES (1) | ES2200052T3 (hu) |
| FI (1) | FI973184A (hu) |
| HK (1) | HK1004659A1 (hu) |
| HR (1) | HRP960045B1 (hu) |
| HU (1) | HUP9800810A3 (hu) |
| IL (1) | IL116925A (hu) |
| IS (1) | IS1970B (hu) |
| MX (1) | MX9705916A (hu) |
| MY (1) | MY121604A (hu) |
| NO (1) | NO314568B1 (hu) |
| NZ (1) | NZ302153A (hu) |
| PE (1) | PE38397A1 (hu) |
| PL (1) | PL182742B1 (hu) |
| PT (1) | PT806957E (hu) |
| SA (1) | SA96160669B1 (hu) |
| SK (1) | SK103797A3 (hu) |
| TR (1) | TR199700735T1 (hu) |
| TW (1) | TW442291B (hu) |
| WO (1) | WO1996023509A1 (hu) |
| YU (1) | YU49417B (hu) |
| ZA (1) | ZA96722B (hu) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4088697A (en) * | 1996-08-26 | 1998-03-19 | Chiron Corporation | Postinfection human immunodeficiency virus (hiv) vaccination therapy |
| WO1999047146A1 (en) * | 1998-03-17 | 1999-09-23 | Julianna Lisziwiewicz | Anti-hiv combination comprising hydroxyurea, ddi, and a protease inhibitor |
| WO1999060988A2 (en) * | 1998-05-29 | 1999-12-02 | University Of Florida | Combination therapy for treatment of fiv infection |
| US6875773B1 (en) | 1998-05-29 | 2005-04-05 | Ben M. Dunn | Combination therapy for treatment of FIV infection |
| EP1141314A2 (en) | 1998-12-31 | 2001-10-10 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| AU2002320314A1 (en) | 2001-07-05 | 2003-01-21 | Chiron, Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| EP1814548A1 (en) * | 2004-11-19 | 2007-08-08 | Boehringer Ingelheim International Gmbh | Method for treating hiv infection through co-administration of tipranavir and reverset |
| WO2007012177A1 (en) * | 2005-07-27 | 2007-02-01 | Emil Toma | Zalcitabine (ddc) boosted lamivudine (3tc) compositions for antiretroviral therapy |
| EP3565554A4 (en) * | 2017-01-04 | 2020-08-19 | Oyagen, Inc. | COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4724232A (en) * | 1985-03-16 | 1988-02-09 | Burroughs Wellcome Co. | Treatment of human viral infections |
| US5254539A (en) * | 1985-08-26 | 1993-10-19 | U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health | Method of treating HIV with 2',3'-dideoxyinosine |
| US5028595A (en) * | 1987-09-18 | 1991-07-02 | Hoffmann-La Roche Inc. | Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus |
| US5204466A (en) | 1990-02-01 | 1993-04-20 | Emory University | Method and compositions for the synthesis of bch-189 and related compounds |
| IL100502A (en) | 1991-01-03 | 1995-12-08 | Iaf Biochem Int | PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (- |
| US5413999A (en) | 1991-11-08 | 1995-05-09 | Merck & Co., Inc. | HIV protease inhibitors useful for the treatment of AIDS |
| CN1090186C (zh) | 1993-03-31 | 2002-09-04 | 麦克公司 | 治疗aids药物组合物中的hiv蛋白酶抑制剂 |
| IL114208A0 (en) | 1994-06-27 | 1995-10-31 | Merck & Co Inc | Combinations of compounds pharmaceutical compositions containing them and their use as hiv protease inhibitors |
-
1995
- 1995-02-01 US US08/382,113 patent/US6689761B1/en not_active Expired - Fee Related
-
1996
- 1996-01-26 IL IL11692596A patent/IL116925A/xx not_active IP Right Cessation
- 1996-01-29 WO PCT/US1996/001417 patent/WO1996023509A1/en not_active Application Discontinuation
- 1996-01-29 NZ NZ302153A patent/NZ302153A/xx unknown
- 1996-01-29 KR KR1019970705253A patent/KR19980701856A/ko not_active Application Discontinuation
- 1996-01-29 JP JP8523739A patent/JPH10513186A/ja not_active Withdrawn
- 1996-01-29 SK SK1037-97A patent/SK103797A3/sk unknown
- 1996-01-29 CN CNB961929103A patent/CN1160081C/zh not_active Expired - Fee Related
- 1996-01-29 PT PT96903770T patent/PT806957E/pt unknown
- 1996-01-29 EP EP96903770A patent/EP0806957B1/en not_active Expired - Lifetime
- 1996-01-29 CA CA002211973A patent/CA2211973A1/en not_active Abandoned
- 1996-01-29 CZ CZ972444A patent/CZ244497A3/cs unknown
- 1996-01-29 AU AU47748/96A patent/AU711176B2/en not_active Ceased
- 1996-01-29 DK DK96903770T patent/DK0806957T3/da active
- 1996-01-29 BR BR9607714A patent/BR9607714A/pt not_active Application Discontinuation
- 1996-01-29 AT AT96903770T patent/ATE243519T1/de not_active IP Right Cessation
- 1996-01-29 MX MX9705916A patent/MX9705916A/es not_active IP Right Cessation
- 1996-01-29 TR TR97/00735T patent/TR199700735T1/xx unknown
- 1996-01-29 HU HU9800810A patent/HUP9800810A3/hu unknown
- 1996-01-29 EA EA199700150A patent/EA000437B1/ru not_active IP Right Cessation
- 1996-01-29 DE DE69628819T patent/DE69628819T2/de not_active Expired - Fee Related
- 1996-01-29 ES ES96903770T patent/ES2200052T3/es not_active Expired - Lifetime
- 1996-01-29 EE EE9700165A patent/EE03514B1/xx not_active IP Right Cessation
- 1996-01-30 HR HR960045A patent/HRP960045B1/xx not_active IP Right Cessation
- 1996-01-31 MY MYPI96000349A patent/MY121604A/en unknown
- 1996-01-31 ZA ZA96722A patent/ZA96722B/xx unknown
- 1996-01-31 DZ DZ960029A patent/DZ1988A1/fr active
- 1996-01-31 PE PE1996000073A patent/PE38397A1/es not_active Application Discontinuation
- 1996-01-31 AR ARP960101221A patent/AR002957A1/es unknown
- 1996-02-01 YU YU6396A patent/YU49417B/sh unknown
- 1996-02-01 CO CO96004316A patent/CO4700430A1/es unknown
- 1996-02-06 TW TW085101447A patent/TW442291B/zh not_active IP Right Cessation
- 1996-03-12 SA SA96160669A patent/SA96160669B1/ar unknown
-
1997
- 1997-07-29 IS IS4533A patent/IS1970B/is unknown
- 1997-07-31 FI FI973184A patent/FI973184A/fi not_active Application Discontinuation
- 1997-07-31 NO NO19973533A patent/NO314568B1/no not_active IP Right Cessation
- 1997-09-29 PL PL96321660A patent/PL182742B1/pl unknown
-
1998
- 1998-05-06 HK HK98103882A patent/HK1004659A1/xx not_active IP Right Cessation
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