HUP9801593A2 - Benazeprilt vagy benazeprilátot és valzartánt tartalmazó kombinált gyógyszerkészítmények és azok alkalmazása - Google Patents

Benazeprilt vagy benazeprilátot és valzartánt tartalmazó kombinált gyógyszerkészítmények és azok alkalmazása

Info

Publication number
HUP9801593A2
HUP9801593A2 HU9801593A HUP9801593A HUP9801593A2 HU P9801593 A2 HUP9801593 A2 HU P9801593A2 HU 9801593 A HU9801593 A HU 9801593A HU P9801593 A HUP9801593 A HU P9801593A HU P9801593 A2 HUP9801593 A2 HU P9801593A2
Authority
HU
Hungary
Prior art keywords
valsartan
benazepril
benazeprilat
formula
compositions containing
Prior art date
Application number
HU9801593A
Other languages
English (en)
Inventor
David Saul Cohen
Marc De Gasparo
Randy Lee Webb
Original Assignee
Novartis Ag.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag. filed Critical Novartis Ag.
Publication of HUP9801593A2 publication Critical patent/HUP9801593A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55—Protease inhibitors
    • A61K38/556—Angiotensin converting enzyme inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány benazeprilt vagy benazeprilátőt és valzartánt tartalmazókőmbinált gyógyszerkészítményekre és azők alkalmazására vőnatkőzik. A találmány szerinti, magas vérnyőmás, pangásős szívelégtelenség ésveseelégtelenség kezelésére alkalmas kőmbinált gyógyszerkészítmények (1) ACE-inhibitőrként (I) képletű benazeprilt vagy (II) képletűbenazeprilátőt vagy egy ezek valamelyikéből előállítható,farmakőlógiai szempőntból elfőgadható sót, és (2) AT1-antagőnistaként (III) képletű valzartánt vagy egy belőleelőállítható, farmakőlógiai szempőntból elfőgadható sót tartalmaznak. A találmány tárgyát képező gyógyszerkészítmény magas vérnyőmás,pangásős szívelégtelenség és veseelégtelenség kezelésére alkalmazható. ŕ
HU9801593A 1995-04-07 1996-04-02 Benazeprilt vagy benazeprilátot és valzartánt tartalmazó kombinált gyógyszerkészítmények és azok alkalmazása HUP9801593A2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH101295 1995-04-07

Publications (1)

Publication Number Publication Date
HUP9801593A2 true HUP9801593A2 (hu) 1999-01-28

Family

ID=4200393

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9801593A HUP9801593A2 (hu) 1995-04-07 1996-04-02 Benazeprilt vagy benazeprilátot és valzartánt tartalmazó kombinált gyógyszerkészítmények és azok alkalmazása

Country Status (15)

Country Link
EP (1) EP0820302A1 (hu)
JP (1) JPH11503139A (hu)
KR (1) KR19980703647A (hu)
CN (1) CN1181019A (hu)
AU (1) AU5399096A (hu)
BR (1) BR9604818A (hu)
CA (1) CA2214143A1 (hu)
CZ (1) CZ313897A3 (hu)
HU (1) HUP9801593A2 (hu)
MX (1) MX9707683A (hu)
NO (1) NO974400D0 (hu)
PL (1) PL322529A1 (hu)
SK (1) SK133897A3 (hu)
TR (1) TR199701121T1 (hu)
WO (1) WO1996031234A1 (hu)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0835106A4 (en) * 1995-06-30 1998-09-30 Merck & Co Inc METHOD FOR TREATING KIDNEY DISEASES USING AN ACE INHIBITOR AND AII ANTAGONIST
CN101011390A (zh) 1999-01-26 2007-08-08 诺瓦提斯公司 血管紧张素ⅱ受体拮抗剂在治疗急性心肌梗塞中的应用
RU2298418C2 (ru) * 2000-04-12 2007-05-10 Новартис Аг Комбинация по меньшей мере двух соединений, выбранных из групп антагонистов at1-рецептора или ингибиторов асе (ангиотензинпревращающий фермент), или ингибиторов hmg-coa-редуктазы (бета-гидрокси-бета-метилглутарил-кофермент-а-редуктаза)
CN1216873C (zh) * 2000-07-19 2005-08-31 诺瓦提斯公司 缬沙坦的盐
GB0020691D0 (en) * 2000-08-22 2000-10-11 Boehringer Ingelheim Pharma Pharmaceutical combination
PL366419A1 (en) * 2000-08-22 2005-01-24 Boehringer Ingelheim Pharma Bmbh & Co.Kg Pharmaceutical combination of angiotensin ii antagonists and angiotensin i converting enzyme inhibitors
WO2002049645A1 (en) * 2000-12-18 2002-06-27 Novartis Ag Therapeutic combination of amlodipine and benazepril
US6869970B2 (en) * 2002-02-04 2005-03-22 Novartis Ag Crystalline salt forms of valsartan
CN1465712A (zh) * 2002-07-05 2004-01-07 安徽省生物医学研究所 一种预测acei类降压药药效的试剂盒、方法、软件和复方药
JP2006516020A (ja) * 2002-08-28 2006-06-15 キュリス インコーポレイテッド 慢性腎不全の治療におけるモルフォゲン及びａｃｅ阻害薬の共投与
EP1908469A1 (en) * 2006-10-06 2008-04-09 Boehringer Ingelheim Vetmedica Gmbh Angiotensin II receptor antagonist for the treatment of systemic diseases in cats
CN101869710A (zh) * 2009-04-24 2010-10-27 北京奥萨医药研究中心有限公司 降压药物组合物
BRPI1013037A2 (pt) 2009-05-20 2019-09-24 Boehringer Ingelheim Ipharmaceuticals Inc "solução farmacêutica oral de telmisartan"
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
MX2016010011A (es) * 2014-01-31 2016-10-07 Janssen Pharmaceutica Nv Metodos para tratar y prevenir trastornos renales y trastornos del higado graso.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR970005839B1 (ko) * 1990-05-11 1997-04-21 화이자 인코포레이티드 상승 치료효과를 얻기 위한 조성물 및 방법
EP0629408A1 (en) * 1993-06-16 1994-12-21 LABORATOIRES MERCK, SHARP & DOHME-CHIBRET Combination of angiotensin converting enzyme inhibitors and AII antagonists

Also Published As

Publication number Publication date
WO1996031234A1 (en) 1996-10-10
TR199701121T1 (xx) 1998-03-21
NO974400L (no) 1997-09-23
NO974400D0 (no) 1997-09-23
BR9604818A (pt) 1998-06-09
EP0820302A1 (en) 1998-01-28
AU5399096A (en) 1996-10-23
CA2214143A1 (en) 1996-10-10
MX9707683A (es) 1997-12-31
KR19980703647A (ko) 1998-12-05
PL322529A1 (en) 1998-02-02
CN1181019A (zh) 1998-05-06
SK133897A3 (en) 1998-02-04
JPH11503139A (ja) 1999-03-23
CZ313897A3 (cs) 1998-01-14

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