EE9700165A - Ühendite kombinatsioon, meetod ja farmatseutiline kompositsioon HIV proteaasi ja HIV pöördtranskriptaasi inhibeerimiseks ning HIV infektsiooni vältimiseks või raviks, või AIDS-i või ARC raviks - Google Patents

Ühendite kombinatsioon, meetod ja farmatseutiline kompositsioon HIV proteaasi ja HIV pöördtranskriptaasi inhibeerimiseks ning HIV infektsiooni vältimiseks või raviks, või AIDS-i või ARC raviks

Info

Publication number
EE9700165A
EE9700165A EE9700165A EE9700165A EE9700165A EE 9700165 A EE9700165 A EE 9700165A EE 9700165 A EE9700165 A EE 9700165A EE 9700165 A EE9700165 A EE 9700165A EE 9700165 A EE9700165 A EE 9700165A
Authority
EE
Estonia
Prior art keywords
hiv
treating
arc
compounds
preventing
Prior art date
Application number
EE9700165A
Other languages
English (en)
Other versions
EE03514B1 (et
Inventor
A. Chodakewitz Jeffrey
A. Emini Emilio
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of EE9700165A publication Critical patent/EE9700165A/et
Publication of EE03514B1 publication Critical patent/EE03514B1/et

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
EE9700165A 1995-02-01 1996-01-29 Ühendite kombinatsioon HIV infektsiooni või AIDS-i raviks, selle kasutamine ja farmatseutiline kompositsioon EE03514B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/382,113 US6689761B1 (en) 1995-02-01 1995-02-01 Combination therapy for HIV infection
PCT/US1996/001417 WO1996023509A1 (en) 1995-02-01 1996-01-29 Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc, optionally together with azt, ddi or ddc

Publications (2)

Publication Number Publication Date
EE9700165A true EE9700165A (et) 1998-02-16
EE03514B1 EE03514B1 (et) 2001-10-15

Family

ID=23507574

Family Applications (1)

Application Number Title Priority Date Filing Date
EE9700165A EE03514B1 (et) 1995-02-01 1996-01-29 Ühendite kombinatsioon HIV infektsiooni või AIDS-i raviks, selle kasutamine ja farmatseutiline kompositsioon

Country Status (38)

Country Link
US (1) US6689761B1 (et)
EP (1) EP0806957B1 (et)
JP (1) JPH10513186A (et)
KR (1) KR19980701856A (et)
CN (1) CN1160081C (et)
AR (1) AR002957A1 (et)
AT (1) ATE243519T1 (et)
AU (1) AU711176B2 (et)
BR (1) BR9607714A (et)
CA (1) CA2211973A1 (et)
CO (1) CO4700430A1 (et)
CZ (1) CZ244497A3 (et)
DE (1) DE69628819T2 (et)
DK (1) DK0806957T3 (et)
DZ (1) DZ1988A1 (et)
EA (1) EA000437B1 (et)
EE (1) EE03514B1 (et)
ES (1) ES2200052T3 (et)
FI (1) FI973184A (et)
HK (1) HK1004659A1 (et)
HR (1) HRP960045B1 (et)
HU (1) HUP9800810A3 (et)
IL (1) IL116925A (et)
IS (1) IS1970B (et)
MX (1) MX9705916A (et)
MY (1) MY121604A (et)
NO (1) NO314568B1 (et)
NZ (1) NZ302153A (et)
PE (1) PE38397A1 (et)
PL (1) PL182742B1 (et)
PT (1) PT806957E (et)
SA (1) SA96160669B1 (et)
SK (1) SK103797A3 (et)
TR (1) TR199700735T1 (et)
TW (1) TW442291B (et)
WO (1) WO1996023509A1 (et)
YU (1) YU49417B (et)
ZA (1) ZA96722B (et)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998008539A1 (en) * 1996-08-26 1998-03-05 Chiron Corporation Postinfection human immunodeficiency virus (hiv) vaccination therapy
AU6761198A (en) * 1998-03-17 1999-10-11 Julianna Lisziwiewicz Anti-hiv combination comprising hydroxyurea, ddi, and a protease inhibitor
US6875773B1 (en) 1998-05-29 2005-04-05 Ben M. Dunn Combination therapy for treatment of FIV infection
AU4219799A (en) * 1998-05-29 1999-12-13 University Of Florida Combination therapy for treatment of fiv infection
JP2003523721A (ja) 1998-12-31 2003-08-12 カイロン コーポレイション 抗原性hivc型ポリペプチドをコードするポリヌクレオチド、ポリペプチド、およびそれらの使用
US7211659B2 (en) 2001-07-05 2007-05-01 Chiron Corporation Polynucleotides encoding antigenic HIV type C polypeptides, polypeptides and uses thereof
US20060128733A1 (en) * 2004-11-19 2006-06-15 Boehringer Ingelheim International Gmbh Method for treating HIV infection through co-administration of tipranavir and reverset
AU2006274455B2 (en) * 2005-07-27 2011-06-09 Emil Toma Zalcitabine (DDC) boosted lamivudine (3TC) compositions for antiretroviral therapy
EP3565554A4 (en) * 2017-01-04 2020-08-19 Oyagen, Inc. COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATMENT OF HUMAN IMMUNODEFICIENCY VIRUS

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4724232A (en) * 1985-03-16 1988-02-09 Burroughs Wellcome Co. Treatment of human viral infections
US5254539A (en) * 1985-08-26 1993-10-19 U.S. Government, Dept. Of Health And Human Services, C/O National Institutes Of Health Method of treating HIV with 2',3'-dideoxyinosine
US5028595A (en) * 1987-09-18 1991-07-02 Hoffmann-La Roche Inc. Method for preventing AIDS in a subject or treating a subject infected with the AIDS virus
US5204466A (en) 1990-02-01 1993-04-20 Emory University Method and compositions for the synthesis of bch-189 and related compounds
IL100502A (en) 1991-01-03 1995-12-08 Iaf Biochem Int PHARMACEUTICAL PREPARATIONS CONTAINING CIS-4-AMINO-1-) 2-HYDROXIMETHIL-1,3-OXETYOLEN-5-IL (-
US5413999A (en) * 1991-11-08 1995-05-09 Merck & Co., Inc. HIV protease inhibitors useful for the treatment of AIDS
CN1090186C (zh) 1993-03-31 2002-09-04 麦克公司 治疗aids药物组合物中的hiv蛋白酶抑制剂
IL114208A0 (en) 1994-06-27 1995-10-31 Merck & Co Inc Combinations of compounds pharmaceutical compositions containing them and their use as hiv protease inhibitors

Also Published As

Publication number Publication date
NO973533L (no) 1997-10-01
BR9607714A (pt) 1998-01-13
PL182742B1 (pl) 2002-02-28
IS4533A (is) 1997-07-29
DK0806957T3 (da) 2003-09-29
HRP960045B1 (en) 2004-06-30
EA199700150A1 (ru) 1997-12-30
HUP9800810A3 (en) 2001-05-28
DZ1988A1 (fr) 2002-07-20
IL116925A (en) 2000-07-26
EP0806957A1 (en) 1997-11-19
FI973184A0 (fi) 1997-07-31
YU49417B (sh) 2006-01-16
ZA96722B (en) 1996-08-26
SK103797A3 (en) 1998-02-04
HRP960045A2 (en) 1997-10-31
US6689761B1 (en) 2004-02-10
SA96160669B1 (ar) 2006-07-30
CZ244497A3 (cs) 1998-01-14
ES2200052T3 (es) 2004-03-01
PL321660A1 (en) 1997-12-22
CN1179722A (zh) 1998-04-22
DE69628819D1 (de) 2003-07-31
CA2211973A1 (en) 1996-08-08
WO1996023509A1 (en) 1996-08-08
IS1970B (is) 2004-12-15
HK1004659A1 (en) 1998-12-04
NO973533D0 (no) 1997-07-31
CO4700430A1 (es) 1998-12-29
NZ302153A (en) 1998-12-23
JPH10513186A (ja) 1998-12-15
HUP9800810A2 (hu) 1998-07-28
MX9705916A (es) 1997-10-31
NO314568B1 (no) 2003-04-14
PE38397A1 (es) 1997-10-09
CN1160081C (zh) 2004-08-04
TR199700735T1 (xx) 1998-02-21
TW442291B (en) 2001-06-23
EA000437B1 (ru) 1999-08-26
KR19980701856A (ko) 1998-06-25
DE69628819T2 (de) 2004-05-13
AR002957A1 (es) 1998-05-27
EP0806957B1 (en) 2003-06-25
MY121604A (en) 2006-02-28
EE03514B1 (et) 2001-10-15
FI973184A (fi) 1997-09-30
YU6396A (sh) 1999-06-15
ATE243519T1 (de) 2003-07-15
AU4774896A (en) 1996-08-21
IL116925A0 (en) 1996-05-14
PT806957E (pt) 2003-10-31
AU711176B2 (en) 1999-10-07

Similar Documents

Publication Publication Date Title
BR9405737A (pt) Composto processo de inibição de transcriptase reserva de HIV, processo de prevenção contra a infecção pelo HIV ou de tratamento da infecção pelo HIV, composição farmacêutica útil para a inibição da transcriptase reserva de HIV, e, útil para a prevenção ou tratamento de infecção pelo HIV ou para o tratamento da AIDS ou ARC
LV12719A (lv) Benzoxazinones as inhibitors of hiv reverse transcriptase
ID26043A (id) Turunan-turunan 1,3,5-triazina tertrisubstitusi untuk pengobatan infeksi-infeksi hiv
MY131388A (en) Inhibitors of hiv protease useful for the treatment of aids.
DK1102588T3 (da) Farmaceutiske sammensætninger til forebyggelse og behandling af sygdomme i centralnervesystemet indeholdende en nikotinanalog og en acetylcholinesteraseinhibitor
ID27457A (id) Komposisi untuk pengobatan hiv dan infeksi virus lainnya
BR9607543A (pt) Inibidores de protease retroviral sulfonamida hidroxietilamino de bis-amino ácido
PL322169A1 (en) Sulphonylalkanoylamino hydroxyethylaminosulphonamides as inhibitors of retroviral protease
ATE312079T1 (de) Nichtnukleoside reverse transkriptase-hemmer zur behandlung von hiv-infektion
BR9408531A (pt) Inibidores da protease hiv e intermediários
EE9700165A (et) Ühendite kombinatsioon, meetod ja farmatseutiline kompositsioon HIV proteaasi ja HIV pöördtranskriptaasi inhibeerimiseks ning HIV infektsiooni vältimiseks või raviks, või AIDS-i või ARC raviks
WO1999009964A3 (de) Pharmazeutische zusammensetzung enthaltend clindamycin und clotrimazol, zur behandlung vaginaler infektion
ZA991029B (en) Composition and methods for treatment of hiv infections.
PL312908A1 (en) Drugs for treating aids and/or hiv infections, containing composition consisting of quinoxalin and protease inhibitors
HUT77573A (hu) Legalább két különböző HIV-1 reverz transzkriptáz inhibitort tartalmazó készítmény HIV-1 fertőzés megelőzésére és kezelésére
WO2001010454A3 (en) Pharmaceutical composition comprising peg-asparaginase for the treatment of hiv infection
AU4602897A (en) Method for treatment of immunodeficiency virus infection
EE9600190A (et) Farmatseutiline kompositsioon viirusinfektsioonide ja võimalike kaasnevate põletike vältimiseks ja/või raviks ning nimetatud haiguste ravimeetod
UA41338C2 (uk) Спосіб інгібування ретровірусної інфекції, яка викликана вірусом імунодефіциту людини (віл), спосіб інгібування вірусу імунодефіциту людини (віл)
DE69529678D1 (de) Kombinationen von hiv-protease inhibitoren
AR015458A1 (es) Compuestos de tetrahidrofurano, y composicion farmaceutica que lo contiene.
PT874863E (pt) Derivados 3-desoxi-3-descladinose de eritromicinasa e b
EE03596B1 (et) Ravim HIVi ja AIDSi raviks ning profülaktikaks
RU93055683A (ru) Ингибиторы вич-протеазы, способ их получения, их использование, композиция
RU93055680A (ru) Ингибиторы вич-протеазы, способ получения, их использование, композиция

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20021231

KB4A Valid patent at the end of a year

Effective date: 20031231

KB4A Valid patent at the end of a year

Effective date: 20041231

KB4A Valid patent at the end of a year

Effective date: 20051231

KB4A Valid patent at the end of a year

Effective date: 20061231

KB4A Valid patent at the end of a year

Effective date: 20071231

MM4A Lapsed by not paying the annual fees

Effective date: 20080129