HUP0303181A2 - 4-Foszfodiészteráz típusú inhibitorok alkalmazása miokardiális betegségek kezelésére alkalmas gyógyszerkészítmények előállítására - Google Patents

4-Foszfodiészteráz típusú inhibitorok alkalmazása miokardiális betegségek kezelésére alkalmas gyógyszerkészítmények előállítására

Info

Publication number
HUP0303181A2
HUP0303181A2 HU0303181A HUP0303181A HUP0303181A2 HU P0303181 A2 HUP0303181 A2 HU P0303181A2 HU 0303181 A HU0303181 A HU 0303181A HU P0303181 A HUP0303181 A HU P0303181A HU P0303181 A2 HUP0303181 A2 HU P0303181A2
Authority
HU
Hungary
Prior art keywords
treating
preparation
type
pharmaceutical compositions
compositions suitable
Prior art date
Application number
HU0303181A
Other languages
English (en)
Inventor
Norbert Beier
Hans-Michael Eggenweiler
Thomas Ehring
Michael Gassen
Joachim Leibrock
Klaus Minck
Pierre Schelling
Arne Sutter
Thomas Welge
Claudia Wilm
Michael Wolf
Original Assignee
Merck Patent Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh. filed Critical Merck Patent Gmbh.
Publication of HUP0303181A2 publication Critical patent/HUP0303181A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/549—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more nitrogen atoms in the same ring, e.g. hydrochlorothiazide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/50—Pyridazines; Hydrogenated pyridazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines having two or more nitrogen atoms in the same ring, e.g. oxadiazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A találmány tárgya különböző 4-foszfodiészteráz típusú inhibitorokalkalmazása miokardiális betegségek kezelésére alkalmasgyógyszerkészítmény előállítására. Előnyösen az (1), (2), (3), (4)vagy (5) képletű vegyületet alkalmazzák. Ó
HU0303181A 2001-02-12 2002-01-15 4-Foszfodiészteráz típusú inhibitorok alkalmazása miokardiális betegségek kezelésére alkalmas gyógyszerkészítmények előállítására HUP0303181A2 (hu)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP01102811 2001-02-12
EP01119875 2001-08-17
PCT/EP2002/000320 WO2002072103A1 (en) 2001-02-12 2002-01-15 Use of type 4 phosphodiesterase inhibitors in myocardial diseases

Publications (1)

Publication Number Publication Date
HUP0303181A2 true HUP0303181A2 (hu) 2004-01-28

Family

ID=26076468

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0303181A HUP0303181A2 (hu) 2001-02-12 2002-01-15 4-Foszfodiészteráz típusú inhibitorok alkalmazása miokardiális betegségek kezelésére alkalmas gyógyszerkészítmények előállítására

Country Status (9)

Country Link
US (1) US20050070529A1 (hu)
EP (1) EP1368035A1 (hu)
JP (1) JP2004521928A (hu)
KR (1) KR20040012720A (hu)
CN (1) CN1235589C (hu)
CA (1) CA2437932A1 (hu)
HU (1) HUP0303181A2 (hu)
NO (1) NO20033541D0 (hu)
WO (1) WO2002072103A1 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2094662B1 (en) 2006-12-14 2012-04-11 Astellas Pharma Inc. Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents
CA2874953A1 (en) 2012-06-12 2013-12-19 Abbvie Inc. Pyridinone and pyridazinone derivatives
EP3661917B1 (en) 2017-08-04 2022-05-11 Bayer Aktiengesellschaft 6-((3-trifluoromethyl)phenyl)-4,5-dihydropyridazin-3(2h)-one derivatives as pde3a and pde3b inhibitors for treating cancer
JOP20200024A1 (ar) 2017-08-04 2020-02-02 Bayer Ag مركبات ثنائي هيدروكساديازينون
WO2020097442A2 (en) * 2018-11-08 2020-05-14 Board Of Regents Of The University Of Nebraska Compositions and methods for the treatment of peripheral artery disease and cardiopulmonary diseases
CN111840557A (zh) * 2019-04-28 2020-10-30 中国医学科学院阜外医院 磷酸二酯酶4抑制剂的用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4310699A1 (de) * 1993-04-01 1994-10-06 Merck Patent Gmbh Thiadiazinone
DE19502699A1 (de) * 1995-01-28 1996-08-01 Merck Patent Gmbh Arylalkyl-thiadiazinone
DE19514568A1 (de) * 1995-04-20 1996-10-24 Merck Patent Gmbh Arylalkyl-pyridazinone
DE19533975A1 (de) * 1995-09-14 1997-03-20 Merck Patent Gmbh Arylalkyl-diazinone
DE19604388A1 (de) * 1996-02-07 1997-08-14 Merck Patent Gmbh Arylalkyl-diazinone
GB9604926D0 (en) * 1996-03-08 1996-05-08 Sandoz Ltd Organic compounds
DE19632549A1 (de) * 1996-08-13 1998-02-19 Merck Patent Gmbh Arylalkanoylpyridazine
DE19737436A1 (de) * 1997-08-21 1999-02-25 Schering Ag Inhibition der Monozyten-Extravasation
DE19826841A1 (de) * 1998-06-16 1999-12-23 Merck Patent Gmbh Arylalkanoylpyridazine
DE19850701A1 (de) * 1998-11-04 2000-05-11 Merck Patent Gmbh Benzoylpyridazine
DE19915365A1 (de) * 1999-04-06 2000-10-12 Merck Patent Gmbh Tetrahydropyridazin-Derivate
US6180650B1 (en) * 1999-04-23 2001-01-30 Merck Frosst Canada & Co. Heterosubstituted pyridine derivatives as PDE 4 inhibitors
DE19932315A1 (de) * 1999-07-10 2001-01-11 Merck Patent Gmbh Benzoylpyridazine

Also Published As

Publication number Publication date
US20050070529A1 (en) 2005-03-31
CN1491112A (zh) 2004-04-21
CN1235589C (zh) 2006-01-11
JP2004521928A (ja) 2004-07-22
CA2437932A1 (en) 2002-09-19
NO20033541L (no) 2003-08-11
WO2002072103A1 (en) 2002-09-19
KR20040012720A (ko) 2004-02-11
EP1368035A1 (en) 2003-12-10
NO20033541D0 (no) 2003-08-11

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees