MA26523A1 - Modification thermodynamiquement stable de 1-(4-carbazolyloxy)-3-(2-(2-methoxyphenoxy) ethylamino)-2-propanole, procede pour sa preparation et compositions pharmaceutiques le comprenant - Google Patents

Modification thermodynamiquement stable de 1-(4-carbazolyloxy)-3-(2-(2-methoxyphenoxy) ethylamino)-2-propanole, procede pour sa preparation et compositions pharmaceutiques le comprenant

Info

Publication number
MA26523A1
MA26523A1 MA25178A MA25178A MA26523A1 MA 26523 A1 MA26523 A1 MA 26523A1 MA 25178 A MA25178 A MA 25178A MA 25178 A MA25178 A MA 25178A MA 26523 A1 MA26523 A1 MA 26523A1
Authority
MA
Morocco
Prior art keywords
carbazolyloxy
propanole
methoxyphenoxy
ethylamino
preparation
Prior art date
Application number
MA25178A
Other languages
English (en)
Inventor
Erhard Reinholz
Peter Beyer
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of MA26523A1 publication Critical patent/MA26523A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
MA25178A 1997-07-22 1998-07-20 Modification thermodynamiquement stable de 1-(4-carbazolyloxy)-3-(2-(2-methoxyphenoxy) ethylamino)-2-propanole, procede pour sa preparation et compositions pharmaceutiques le comprenant MA26523A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97112491A EP0893440A1 (fr) 1997-07-22 1997-07-22 Une modification thermodynamique stabilisée de 1-(4-carbazolyloxy)-3[2-(2-methoxyphenoxy)ethylamino]- 2-propanole, un procédé pour sa préparation et une composition pharmaceutique qui la contient

Publications (1)

Publication Number Publication Date
MA26523A1 true MA26523A1 (fr) 2004-12-20

Family

ID=8227094

Family Applications (1)

Application Number Title Priority Date Filing Date
MA25178A MA26523A1 (fr) 1997-07-22 1998-07-20 Modification thermodynamiquement stable de 1-(4-carbazolyloxy)-3-(2-(2-methoxyphenoxy) ethylamino)-2-propanole, procede pour sa preparation et compositions pharmaceutiques le comprenant

Country Status (32)

Country Link
EP (2) EP0893440A1 (fr)
JP (1) JP2001510824A (fr)
KR (1) KR100336229B1 (fr)
CN (1) CN1125047C (fr)
AR (1) AR015133A1 (fr)
AT (1) ATE236123T1 (fr)
AU (1) AU740453B2 (fr)
BR (1) BR9810776A (fr)
CA (1) CA2296637C (fr)
CZ (1) CZ296947B6 (fr)
DE (1) DE69812964T2 (fr)
DK (1) DK1000027T3 (fr)
ES (1) ES2195366T3 (fr)
HK (1) HK1029339A1 (fr)
HR (1) HRP980406A2 (fr)
HU (1) HUP0003198A3 (fr)
IL (1) IL133677A (fr)
MA (1) MA26523A1 (fr)
MY (1) MY117734A (fr)
NO (1) NO313588B1 (fr)
NZ (1) NZ502136A (fr)
PE (1) PE96999A1 (fr)
PL (1) PL191602B1 (fr)
PT (1) PT1000027E (fr)
RU (1) RU2202542C2 (fr)
SI (1) SI1000027T1 (fr)
TR (1) TR200000148T2 (fr)
TW (1) TW505631B (fr)
UY (1) UY25108A1 (fr)
WO (1) WO1999005105A1 (fr)
YU (1) YU2200A (fr)
ZA (1) ZA986475B (fr)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003528914A (ja) * 2000-04-03 2003-09-30 エフ．ホフマン−ラ ロシュ アーゲー カルベジロールの濃縮溶液
MXPA02012795A (es) 2000-06-28 2004-07-30 Teva Pharma Carvedilol.
EP1655285A1 (fr) * 2000-06-28 2006-05-10 Teva Pharmaceutical Industries Ltd. Procédé de préparation d'une forme crystalline de carvedilol (forme II)
EP1406614B1 (fr) * 2001-07-13 2006-06-07 Smithkline Beecham Corporation Polymorphe de carvedilol
WO2003024426A1 (fr) 2001-09-21 2003-03-27 Egalet A/S Dispersions solides a liberation controlee
BR0212927A (pt) * 2001-09-28 2004-10-13 Hoffmann La Roche Formas pseudopolimórficas de carvedilol
PL371409A1 (en) * 2002-01-15 2005-06-13 Teva Pharmaceutical Industries Ltd. Crystalline solids of carvedilol and processes for their preparation
EP1499310A4 (fr) * 2002-04-30 2005-12-07 Sb Pharmco Inc Monocitrate monohydrate de carvedilol
US20050261355A1 (en) 2002-06-27 2005-11-24 Sb Pharmco Puerto Rico Inc., Carvedilol hydobromide
MXPA04012923A (es) 2002-06-27 2005-03-31 Sb Pharmco Inc Sales de fosfato de carvedilol y/o solvatos de las mismas, composiciones correspondientes y/o metodos de tratamiento.
WO2004041252A1 (fr) * 2002-11-08 2004-05-21 Egalet A/S Compositions de carvedilol a liberation commandee
EP2301526B1 (fr) 2003-03-26 2016-03-23 Egalet Ltd. Système de libération contrôlée de morphine
EP1615888A1 (fr) 2003-04-21 2006-01-18 Matrix Laboratories Ltd Procede de fabrication de carvedilol, forme-ii
SI21616A (sl) * 2003-09-02 2005-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Nove kristalne oblike karvedilola
JP2007512372A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール塩、対応する組成物、送達および／または治療方法
PL1838670T3 (pl) * 2004-12-09 2010-03-31 Zach System Spa Sposób wytwarzania karwedilolu i jego enancjomerów
US20070043099A1 (en) * 2005-06-09 2007-02-22 Igor Lifshitz Crystalline forms of carvedilol and processes for their preparation
US8022094B2 (en) 2006-06-28 2011-09-20 Teva Pharmaceutical Industries Ltd. Carvedilol phosphate
US20080249317A1 (en) * 2007-04-04 2008-10-09 Apotex Inc. Novel amorphous form of carvedilol phosphate and processes for the preparation thereof
NZ580972A (en) 2007-06-04 2012-02-24 Egalet Ltd Controlled release pharmaceutical compositions for prolonged effect
WO2010089132A1 (fr) 2009-02-06 2010-08-12 Egalet A/S Composition à libération immédiate résistant à une maltraitance par prise d'alcool
WO2010149169A2 (fr) 2009-06-24 2010-12-29 Egalet A/S Formulations à libération contrôlée

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) * 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) * 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten

Also Published As

Publication number Publication date
SI1000027T1 (en) 2003-10-31
EP0893440A1 (fr) 1999-01-27
AR015133A1 (es) 2001-04-18
DE69812964D1 (de) 2003-05-08
TR200000148T2 (tr) 2000-07-21
ZA986475B (en) 2000-01-21
EP1000027B1 (fr) 2003-04-02
HUP0003198A3 (en) 2002-10-28
DK1000027T3 (da) 2003-07-21
PL191602B1 (pl) 2006-06-30
AU740453B2 (en) 2001-11-01
HUP0003198A2 (en) 2001-03-28
HK1029339A1 (en) 2001-03-30
WO1999005105A1 (fr) 1999-02-04
DE69812964T2 (de) 2004-03-04
NO313588B1 (no) 2002-10-28
IL133677A0 (en) 2001-04-30
KR100336229B1 (ko) 2002-05-09
BR9810776A (pt) 2000-09-19
NO20000301D0 (no) 2000-01-21
NZ502136A (en) 2002-05-31
PE96999A1 (es) 1999-10-12
CZ2000221A3 (cs) 2000-05-17
PL338432A1 (en) 2000-11-06
CN1125047C (zh) 2003-10-22
CN1264366A (zh) 2000-08-23
CA2296637A1 (fr) 1999-02-04
EP1000027A1 (fr) 2000-05-17
HRP980406A2 (en) 1999-04-30
YU2200A (sh) 2002-03-18
IL133677A (en) 2004-06-01
UY25108A1 (es) 2000-12-29
NO20000301L (no) 2000-01-21
TW505631B (en) 2002-10-11
MY117734A (en) 2004-07-31
CZ296947B6 (cs) 2006-08-16
ES2195366T3 (es) 2003-12-01
PT1000027E (pt) 2003-07-31
AU8631998A (en) 1999-02-16
RU2202542C2 (ru) 2003-04-20
CA2296637C (fr) 2005-11-15
ATE236123T1 (de) 2003-04-15
JP2001510824A (ja) 2001-08-07
KR20010022097A (ko) 2001-03-15

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