MA25223A1 - Procede pour la preparation de 4-carboxy-amino-2-substitue-1,2,3,4 tetrahydroquinoleine - Google Patents

Procede pour la preparation de 4-carboxy-amino-2-substitue-1,2,3,4 tetrahydroquinoleine

Info

Publication number
MA25223A1
MA25223A1 MA26112A MA26112A MA25223A1 MA 25223 A1 MA25223 A1 MA 25223A1 MA 26112 A MA26112 A MA 26112A MA 26112 A MA26112 A MA 26112A MA 25223 A1 MA25223 A1 MA 25223A1
Authority
MA
Morocco
Prior art keywords
tetrahydroquinoleine
substitue
carboxy
amino
preparation
Prior art date
Application number
MA26112A
Other languages
English (en)
Inventor
Wayne Dugger Robert
Burns Damon David
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of MA25223A1 publication Critical patent/MA25223A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
MA26112A 1999-11-30 2000-11-29 Procede pour la preparation de 4-carboxy-amino-2-substitue-1,2,3,4 tetrahydroquinoleine MA25223A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16796799P 1999-11-30 1999-11-30

Publications (1)

Publication Number Publication Date
MA25223A1 true MA25223A1 (fr) 2001-07-02

Family

ID=22609556

Family Applications (1)

Application Number Title Priority Date Filing Date
MA26112A MA25223A1 (fr) 1999-11-30 2000-11-29 Procede pour la preparation de 4-carboxy-amino-2-substitue-1,2,3,4 tetrahydroquinoleine

Country Status (45)

Country Link
US (1) US6313142B1 (fr)
EP (1) EP1125929B1 (fr)
JP (1) JP3579345B2 (fr)
KR (1) KR100408177B1 (fr)
CN (1) CN1173953C (fr)
AP (1) AP2000002011A0 (fr)
AR (1) AR029775A1 (fr)
AT (1) ATE315028T1 (fr)
AU (1) AU784694B2 (fr)
BG (1) BG105009A (fr)
BR (1) BR0005636A (fr)
CA (1) CA2327029C (fr)
CO (1) CO5261552A1 (fr)
CY (1) CY1104989T1 (fr)
CZ (1) CZ20004407A3 (fr)
DE (1) DE60025317T2 (fr)
DK (1) DK1125929T3 (fr)
DZ (1) DZ3079A1 (fr)
EA (1) EA003668B1 (fr)
EE (1) EE200000659A (fr)
ES (1) ES2254109T3 (fr)
GE (1) GEP20022798B (fr)
GT (1) GT200000190A (fr)
HK (1) HK1038007A1 (fr)
HN (1) HN2000000203A (fr)
HR (1) HRP20000804A2 (fr)
HU (1) HUP0004747A3 (fr)
ID (1) ID28489A (fr)
IL (1) IL139849A (fr)
IS (1) IS5715A (fr)
MA (1) MA25223A1 (fr)
NO (1) NO20006039L (fr)
NZ (1) NZ508509A (fr)
OA (1) OA11494A (fr)
PA (1) PA8503801A1 (fr)
PE (1) PE20010913A1 (fr)
PL (1) PL344208A1 (fr)
SG (1) SG102603A1 (fr)
SK (1) SK17792000A3 (fr)
TN (1) TNSN00230A1 (fr)
TW (1) TW591016B (fr)
UA (1) UA65615C2 (fr)
UY (1) UY26451A1 (fr)
YU (1) YU71500A (fr)
ZA (1) ZA200006947B (fr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HN2000000203A (es) * 1999-11-30 2001-06-13 Pfizer Prod Inc Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas 4-carboxiamino-2- sustituidas.
US7202247B2 (en) 2001-12-19 2007-04-10 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders
CN1596240A (zh) * 2001-12-19 2005-03-16 阿特罗吉尼克斯公司 查耳酮衍生物及其治疗疾病的用途
EP1492880B1 (fr) * 2002-04-11 2008-10-08 Roar Holding LLC Procede ex vivo permettant de determiner l'activite de cetp et l'efficacite d'un traitement d'une cardiopathie
US20090181966A1 (en) * 2002-10-04 2009-07-16 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
US7504508B2 (en) * 2002-10-04 2009-03-17 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
AU2003277285B2 (en) * 2002-10-04 2007-12-13 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
US7223870B2 (en) * 2002-11-01 2007-05-29 Pfizer Inc. Methods for preparing N-arylated oxazolidinones via a copper catalyzed cross coupling reaction
AU2003303239A1 (en) * 2002-12-19 2004-07-14 Atherogenics, Inc. Process of making chalcone derivatives
AU2003283769A1 (en) 2002-12-20 2004-07-14 Pfizer Products Inc. Dosage forms comprising a cetp inhibitor and an hmg-coa reductase inhibitor
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
US20060100239A1 (en) * 2003-03-04 2006-05-11 Izuru Nagasaki Method for producing optically active amines
JP5546715B2 (ja) * 2003-03-17 2014-07-09 日本たばこ産業株式会社 Ｃｅｔｐ阻害剤の医薬組成物
BRPI0408442A (pt) * 2003-03-17 2006-04-04 Japan Tobacco Inc método para aumento da biodisponibilidade oral de s-[2-([[1-(2-etilbutil)ciclohexil]carbonil]amino)fenil]2- metilpropanotioato
TWI494102B (zh) * 2003-05-02 2015-08-01 Japan Tobacco Inc 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合
MXPA06003927A (es) * 2003-10-08 2008-02-07 Lilly Co Eli Compuestos y metodos para tratar dislipidemia.
UA90269C2 (ru) * 2004-04-02 2010-04-26 Мицубиси Танабе Фарма Корпорейшн Тетрагидрохинолиновые производные и способ их получения
WO2006012093A1 (fr) * 2004-06-24 2006-02-02 Eli Lilly And Company Composés et procédés destinés à traiter la dyslipidémie
DOP2005000123A (es) 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
WO2006033001A1 (fr) * 2004-09-23 2006-03-30 Pfizer Products Inc. Composes de quinoline
WO2006069162A1 (fr) * 2004-12-20 2006-06-29 Reddy Us Therapeutics, Inc. Nouveaux composes heterocycliques et leurs compositions pharmaceutiques
KR20070114762A (ko) * 2005-02-24 2007-12-04 밀레니엄 파머슈티컬스 인코퍼레이티드 염증 질환 치료를 위한 ｐｇｄ2 수용체 길항제
UY30244A1 (es) 2006-03-30 2007-11-30 Tanabe Seiyaku Co Un proceso para preparar derivados de tetrahidroquinolina
EP2134169A2 (fr) 2007-03-09 2009-12-23 Indigene Pharmaceuticals Inc. Combinaison de metformine r-(+) lipoate et d'agents antihyperlipidémiques pour le traitement de l'hyperglycémie diabétique et de complications diabétiques
CN101429160B (zh) * 2007-11-06 2011-10-19 上海药明康德新药开发有限公司 一种1-r-4-氨基-1,2,3,4-四氢喹啉的合成方法
AR077208A1 (es) * 2009-06-30 2011-08-10 Lilly Co Eli Derivados del acido trans-4-[[(5s)-5-[[[3,5-bis(trifluorometil) fenil] metil] (2-metil-2h-tetrazol-5-il) amino) -2,3,4,5-tetrahidro-7,9-dimetil-1h-1-benzazepin-1-il) metil)-ciclohexancarboxilico y sus formas cristalinas, composiciones farmaceuticas que los comprenden, su uso para preparar un medicam

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR7870M (fr) * 1968-11-08 1970-04-27
US3971789A (en) 1972-10-21 1976-07-27 John Wyeth & Brother Limited O-(4-Quinolylamino)benzamides
GB8432091D0 (en) 1984-12-19 1985-01-30 Wyeth John & Brother Ltd 4-aminoquinoline derivatives
US4839368A (en) 1986-05-02 1989-06-13 Mochida Pharmaceutical Co., Ltd. 1-acyl-2,3-dihydro-4(1H)-quinolinone-4-oxime derivatives
GB8804444D0 (en) 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5231102A (en) 1989-03-08 1993-07-27 Merck Sharp & Dohme, Ltd. Tetrahydroquinoline derivatives useful for neurodegenerative disorders
PT100905A (pt) * 1991-09-30 1994-02-28 Eisai Co Ltd Compostos heterociclicos azotados biciclicos contendo aneis de benzeno, ciclo-hexano ou piridina e de pirimidina, piridina ou imidazol substituidos e composicoes farmaceuticas que os contem
US6197786B1 (en) * 1998-09-17 2001-03-06 Pfizer Inc 4-Carboxyamino-2-substituted-1,2,3,4-tetrahydroquinolines
US6147089A (en) 1998-09-17 2000-11-14 Pfizer Inc. Annulated 4-carboxyamino-2-methyl-1,2,3,4,-tetrahydroquinolines
US6140342A (en) 1998-09-17 2000-10-31 Pfizer Inc. Oxy substituted 4-carboxyamino-2-methyl-1,2,3,4-tetrahydroquinolines
HN2000000203A (es) * 1999-11-30 2001-06-13 Pfizer Prod Inc Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas 4-carboxiamino-2- sustituidas.

Also Published As

Publication number Publication date
IL139849A (en) 2006-10-31
HN2000000203A (es) 2001-06-13
AR029775A1 (es) 2003-07-16
EA200001129A2 (ru) 2001-06-25
PA8503801A1 (es) 2002-07-30
ATE315028T1 (de) 2006-02-15
CO5261552A1 (es) 2003-03-31
HU0004747D0 (fr) 2001-02-28
TNSN00230A1 (fr) 2005-11-10
JP2001163859A (ja) 2001-06-19
HK1038007A1 (en) 2002-03-01
NZ508509A (en) 2001-06-29
ES2254109T3 (es) 2006-06-16
GT200000190A (es) 2002-04-27
JP3579345B2 (ja) 2004-10-20
PL344208A1 (en) 2001-06-04
KR100408177B1 (ko) 2003-12-01
AU7178900A (en) 2001-05-31
AU784694B2 (en) 2006-06-01
UY26451A1 (es) 2001-06-29
SG102603A1 (en) 2004-03-26
YU71500A (sh) 2003-02-28
BG105009A (en) 2001-11-30
CA2327029C (fr) 2005-08-09
CZ20004407A3 (cs) 2002-06-12
KR20010052012A (ko) 2001-06-25
EA200001129A3 (ru) 2001-10-22
ID28489A (id) 2001-05-31
DE60025317D1 (de) 2006-03-30
US6313142B1 (en) 2001-11-06
NO20006039D0 (no) 2000-11-29
CN1173953C (zh) 2004-11-03
GEP20022798B (en) 2002-09-25
ZA200006947B (en) 2002-05-27
NO20006039L (no) 2001-05-31
IL139849A0 (en) 2002-02-10
CY1104989T1 (el) 2010-03-03
SK17792000A3 (sk) 2002-10-08
OA11494A (en) 2004-05-07
AP2000002011A0 (en) 2000-12-31
DE60025317T2 (de) 2006-08-03
BR0005636A (pt) 2001-07-17
HRP20000804A2 (en) 2001-06-30
EE200000659A (et) 2001-08-15
CN1302800A (zh) 2001-07-11
EP1125929A1 (fr) 2001-08-22
TW591016B (en) 2004-06-11
HUP0004747A2 (hu) 2001-10-28
HUP0004747A3 (en) 2002-12-28
UA65615C2 (uk) 2004-04-15
DK1125929T3 (da) 2006-04-03
DZ3079A1 (fr) 2004-10-24
CA2327029A1 (fr) 2001-05-30
EP1125929B1 (fr) 2006-01-04
EA003668B1 (ru) 2003-08-28
PE20010913A1 (es) 2001-09-10
IS5715A (is) 2001-05-31

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