UY26451A1 - Procedimiento para la obtención de 1,2,3,4- tetrahidroquinolinas 4-carboxiamino-2-sustituidas - Google Patents

Procedimiento para la obtención de 1,2,3,4- tetrahidroquinolinas 4-carboxiamino-2-sustituidas

Info

Publication number
UY26451A1
UY26451A1 UY26451A UY26451A UY26451A1 UY 26451 A1 UY26451 A1 UY 26451A1 UY 26451 A UY26451 A UY 26451A UY 26451 A UY26451 A UY 26451A UY 26451 A1 UY26451 A1 UY 26451A1
Authority
UY
Uruguay
Prior art keywords
tetrahydrokinolins
carboxiamino
substituted
procedure
obtaining
Prior art date
Application number
UY26451A
Other languages
English (en)
Inventor
David Burns
Robert Wayne Dugget
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of UY26451A1 publication Critical patent/UY26451A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Se describieron procedimientos para preparar inhibidores de CETP.
UY26451A 1999-11-30 2000-11-27 Procedimiento para la obtención de 1,2,3,4- tetrahidroquinolinas 4-carboxiamino-2-sustituidas UY26451A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US16796799P 1999-11-30 1999-11-30

Publications (1)

Publication Number Publication Date
UY26451A1 true UY26451A1 (es) 2001-06-29

Family

ID=22609556

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26451A UY26451A1 (es) 1999-11-30 2000-11-27 Procedimiento para la obtención de 1,2,3,4- tetrahidroquinolinas 4-carboxiamino-2-sustituidas

Country Status (45)

Country Link
US (1) US6313142B1 (es)
EP (1) EP1125929B1 (es)
JP (1) JP3579345B2 (es)
KR (1) KR100408177B1 (es)
CN (1) CN1173953C (es)
AP (1) AP2000002011A0 (es)
AR (1) AR029775A1 (es)
AT (1) ATE315028T1 (es)
AU (1) AU784694B2 (es)
BG (1) BG105009A (es)
BR (1) BR0005636A (es)
CA (1) CA2327029C (es)
CO (1) CO5261552A1 (es)
CY (1) CY1104989T1 (es)
CZ (1) CZ20004407A3 (es)
DE (1) DE60025317T2 (es)
DK (1) DK1125929T3 (es)
DZ (1) DZ3079A1 (es)
EA (1) EA003668B1 (es)
EE (1) EE200000659A (es)
ES (1) ES2254109T3 (es)
GE (1) GEP20022798B (es)
GT (1) GT200000190A (es)
HK (1) HK1038007A1 (es)
HN (1) HN2000000203A (es)
HR (1) HRP20000804A2 (es)
HU (1) HUP0004747A3 (es)
ID (1) ID28489A (es)
IL (1) IL139849A (es)
IS (1) IS5715A (es)
MA (1) MA25223A1 (es)
NO (1) NO20006039L (es)
NZ (1) NZ508509A (es)
OA (1) OA11494A (es)
PA (1) PA8503801A1 (es)
PE (1) PE20010913A1 (es)
PL (1) PL344208A1 (es)
SG (1) SG102603A1 (es)
SK (1) SK17792000A3 (es)
TN (1) TNSN00230A1 (es)
TW (1) TW591016B (es)
UA (1) UA65615C2 (es)
UY (1) UY26451A1 (es)
YU (1) YU71500A (es)
ZA (1) ZA200006947B (es)

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AU2002361811A1 (en) 2001-12-19 2003-07-09 Atherogenics, Inc. 1,3-bis-(substituted-phenyl)-2-propyn-1-ones and their use to treat disorders
EP1465854A4 (en) * 2001-12-19 2005-06-08 Atherogenics Inc CHALCONE DERIVATIVES AND THEIR USE IN THE TREATMENT OF DISEASES
DE60323954D1 (de) * 2002-04-11 2008-11-20 Roar Holding Llc Ex-vivo-verfahren zur bestimmung der cetp-aktivität und der wirksamkeit der behandlung von herzerkrankungen
US20090181966A1 (en) * 2002-10-04 2009-07-16 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
US7504508B2 (en) * 2002-10-04 2009-03-17 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
AU2003277285B2 (en) * 2002-10-04 2007-12-13 Millennium Pharmaceuticals, Inc. PGD2 receptor antagonists for the treatment of inflammatory diseases
US7223870B2 (en) * 2002-11-01 2007-05-29 Pfizer Inc. Methods for preparing N-arylated oxazolidinones via a copper catalyzed cross coupling reaction
AU2003303239A1 (en) * 2002-12-19 2004-07-14 Atherogenics, Inc. Process of making chalcone derivatives
US20040132771A1 (en) * 2002-12-20 2004-07-08 Pfizer Inc Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
CA2508840A1 (en) 2002-12-20 2004-07-08 Pfizer Products Inc. Dosage forms comprising a cetp inhibitor and an hmg-coa reductase inhibitor
US20060100239A1 (en) * 2003-03-04 2006-05-11 Izuru Nagasaki Method for producing optically active amines
MXPA05009976A (es) * 2003-03-17 2005-11-04 Japan Tobacco Inc Metodo para incrementar la biodisponibilidad oral del 2-metilpropantioato de s-[2-([[1- 2-etilbutil) ciclohexil] carbonil] amino) fenilo].
CA2519432C (en) * 2003-03-17 2009-06-09 Japan Tobacco Inc. Pharmaceutical compositions comprising cetp inhibitors and a water-insoluble concentration-enhancing additive for the treatment of cardiovascular disease
TWI393560B (zh) * 2003-05-02 2013-04-21 Japan Tobacco Inc 包含ｓ-〔２（〔〔１-（２-乙基丁基）環己基〕羰基〕胺基）苯基〕２-甲基丙烷硫酯及ｈｍｇ輔酶ａ還原酶抑制劑之組合
EA200600737A1 (ru) * 2003-10-08 2006-10-27 Эли Лилли Энд Компани Соединения и способы для лечения дислипидемии
UA90269C2 (ru) * 2004-04-02 2010-04-26 Мицубиси Танабе Фарма Корпорейшн Тетрагидрохинолиновые производные и способ их получения
US20080269284A1 (en) * 2004-06-24 2008-10-30 Eli Lilly And Company Compounds and Methods for Treating Dyslipidemia
DOP2005000123A (es) * 2004-07-02 2011-07-15 Merck Sharp & Dohme Inhibidores de cetp
WO2006033001A1 (en) * 2004-09-23 2006-03-30 Pfizer Products Inc. Quinoline compounds
WO2006069162A1 (en) * 2004-12-20 2006-06-29 Reddy Us Therapeutics, Inc. Novel heterocyclic compounds and their pharmaceutical compositions
CN101146776A (zh) * 2005-02-24 2008-03-19 米伦纽姆医药公司 治疗炎性疾病的pgd2受体拮抗剂
UY30244A1 (es) 2006-03-30 2007-11-30 Tanabe Seiyaku Co Un proceso para preparar derivados de tetrahidroquinolina
CL2008000684A1 (es) 2007-03-09 2008-08-01 Indigene Pharmaceuticals Inc Composicion farmaceutica que comprende metformina r-(+) lipoato y un inhibidor de reductasa hmg-coa; formulacion de dosis unitaria; y uso en el tratamiento de una complicacion diabetica.
CN101429160B (zh) * 2007-11-06 2011-10-19 上海药明康德新药开发有限公司 一种1-r-4-氨基-1,2,3,4-四氢喹啉的合成方法
TWI450896B (zh) * 2009-06-30 2014-09-01 Lilly Co Eli 反式－４－〔〔（５ｓ）－５－〔〔〔３，５－雙（三氟甲基）苯基〕甲基〕（２－甲基－２ｈ－四唑－５－基）胺基〕－２，３，４，５－四氫－７，９－二甲基－１ｈ－１－苯并氮呯－１－基〕甲基〕－環己基羧酸

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HN2000000203A (es) * 1999-11-30 2001-06-13 Pfizer Prod Inc Procedimiento para la obtencion de 1,2,3,4-tetrahidroquinolinas 4-carboxiamino-2- sustituidas.

Also Published As

Publication number Publication date
NO20006039L (no) 2001-05-31
CA2327029C (en) 2005-08-09
UA65615C2 (uk) 2004-04-15
IL139849A0 (en) 2002-02-10
MA25223A1 (fr) 2001-07-02
PA8503801A1 (es) 2002-07-30
DE60025317T2 (de) 2006-08-03
TNSN00230A1 (fr) 2005-11-10
CO5261552A1 (es) 2003-03-31
CZ20004407A3 (cs) 2002-06-12
PE20010913A1 (es) 2001-09-10
HK1038007A1 (en) 2002-03-01
OA11494A (en) 2004-05-07
KR100408177B1 (ko) 2003-12-01
ZA200006947B (en) 2002-05-27
CN1173953C (zh) 2004-11-03
EE200000659A (et) 2001-08-15
BR0005636A (pt) 2001-07-17
NO20006039D0 (no) 2000-11-29
SK17792000A3 (sk) 2002-10-08
HUP0004747A3 (en) 2002-12-28
CA2327029A1 (en) 2001-05-30
ID28489A (id) 2001-05-31
AR029775A1 (es) 2003-07-16
GT200000190A (es) 2002-04-27
DE60025317D1 (de) 2006-03-30
HUP0004747A2 (hu) 2001-10-28
ATE315028T1 (de) 2006-02-15
HN2000000203A (es) 2001-06-13
GEP20022798B (en) 2002-09-25
AP2000002011A0 (en) 2000-12-31
CY1104989T1 (el) 2010-03-03
BG105009A (en) 2001-11-30
HRP20000804A2 (en) 2001-06-30
AU7178900A (en) 2001-05-31
TW591016B (en) 2004-06-11
JP3579345B2 (ja) 2004-10-20
EA003668B1 (ru) 2003-08-28
IS5715A (is) 2001-05-31
CN1302800A (zh) 2001-07-11
DZ3079A1 (fr) 2004-10-24
DK1125929T3 (da) 2006-04-03
PL344208A1 (en) 2001-06-04
HU0004747D0 (es) 2001-02-28
IL139849A (en) 2006-10-31
US6313142B1 (en) 2001-11-06
EP1125929A1 (en) 2001-08-22
NZ508509A (en) 2001-06-29
AU784694B2 (en) 2006-06-01
EP1125929B1 (en) 2006-01-04
YU71500A (sh) 2003-02-28
KR20010052012A (ko) 2001-06-25
JP2001163859A (ja) 2001-06-19
SG102603A1 (en) 2004-03-26
EA200001129A2 (ru) 2001-06-25
ES2254109T3 (es) 2006-06-16
EA200001129A3 (ru) 2001-10-22

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Legal Events

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109 Application deemed to be withdrawn

Effective date: 20121121