DK1000027T3 - Termodynamisk stabil modifikation af 1-(4-carbazolyloxy)-3-[2-(methoxyphenoxy)ethylamino]-2-propanol, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende denne - Google Patents
Termodynamisk stabil modifikation af 1-(4-carbazolyloxy)-3-[2-(methoxyphenoxy)ethylamino]-2-propanol, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende denneInfo
- Publication number
- DK1000027T3 DK1000027T3 DK98937576T DK98937576T DK1000027T3 DK 1000027 T3 DK1000027 T3 DK 1000027T3 DK 98937576 T DK98937576 T DK 98937576T DK 98937576 T DK98937576 T DK 98937576T DK 1000027 T3 DK1000027 T3 DK 1000027T3
- Authority
- DK
- Denmark
- Prior art keywords
- carbazolyloxy
- methoxyphenoxy
- ethylamino
- propanol
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97112491A EP0893440A1 (en) | 1997-07-22 | 1997-07-22 | Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it |
| PCT/EP1998/004475 WO1999005105A1 (en) | 1997-07-22 | 1998-07-18 | Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1000027T3 true DK1000027T3 (da) | 2003-07-21 |
Family
ID=8227094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98937576T DK1000027T3 (da) | 1997-07-22 | 1998-07-18 | Termodynamisk stabil modifikation af 1-(4-carbazolyloxy)-3-[2-(methoxyphenoxy)ethylamino]-2-propanol, fremgangsmåde til fremstilling deraf og farmaceutiske præparater indeholdende denne |
Country Status (32)
| Country | Link |
|---|---|
| EP (2) | EP0893440A1 (da) |
| JP (1) | JP2001510824A (da) |
| KR (1) | KR100336229B1 (da) |
| CN (1) | CN1125047C (da) |
| AR (1) | AR015133A1 (da) |
| AT (1) | ATE236123T1 (da) |
| AU (1) | AU740453B2 (da) |
| BR (1) | BR9810776A (da) |
| CA (1) | CA2296637C (da) |
| CZ (1) | CZ296947B6 (da) |
| DE (1) | DE69812964T2 (da) |
| DK (1) | DK1000027T3 (da) |
| ES (1) | ES2195366T3 (da) |
| HK (1) | HK1029339A1 (da) |
| HR (1) | HRP980406A2 (da) |
| HU (1) | HUP0003198A3 (da) |
| IL (1) | IL133677A (da) |
| MA (1) | MA26523A1 (da) |
| MY (1) | MY117734A (da) |
| NO (1) | NO313588B1 (da) |
| NZ (1) | NZ502136A (da) |
| PE (1) | PE96999A1 (da) |
| PL (1) | PL191602B1 (da) |
| PT (1) | PT1000027E (da) |
| RU (1) | RU2202542C2 (da) |
| SI (1) | SI1000027T1 (da) |
| TR (1) | TR200000148T2 (da) |
| TW (1) | TW505631B (da) |
| UY (1) | UY25108A1 (da) |
| WO (1) | WO1999005105A1 (da) |
| YU (1) | YU2200A (da) |
| ZA (1) | ZA986475B (da) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60105996T2 (de) * | 2000-04-03 | 2006-03-09 | F. Hoffmann-La Roche Ag | Konzentrierte lösungen von carvedilol |
| CN1245974C (zh) | 2000-06-28 | 2006-03-22 | 特瓦制药工业有限公司 | 卡维地洛 |
| EP1655285A1 (en) * | 2000-06-28 | 2006-05-10 | Teva Pharmaceutical Industries Ltd. | Method for preparation of a crystalline form of carvedilol (form II) |
| AU2002326391A1 (en) * | 2001-07-13 | 2003-01-29 | Smithkline Beecham Corporation | Carvedilol polymorph |
| DE60224293T2 (de) | 2001-09-21 | 2008-12-11 | Egalet A/S | Feste dispersionen mit kontrollierter freisetzung von carvedilol |
| KR100752549B1 (ko) * | 2001-09-28 | 2007-08-30 | 에프. 호프만-라 로슈 아게 | 카르베딜올의 유사다형태 |
| CN1298322C (zh) * | 2002-01-15 | 2007-02-07 | 特瓦制药工业有限公司 | 卡维地洛的结晶固体及其制备方法 |
| WO2003092622A2 (en) * | 2002-04-30 | 2003-11-13 | Sb Pharmco Puerto Rico Inc. | Carvedilol monocitrate monohydrate |
| US20050261355A1 (en) | 2002-06-27 | 2005-11-24 | Sb Pharmco Puerto Rico Inc., | Carvedilol hydobromide |
| KR20110134952A (ko) * | 2002-06-27 | 2011-12-15 | 스미스클라인 비이참 (코르크) 리미티드 | 카베딜롤 인산염 및(또는) 그의 용매화물, 상응하는 조성물, 및(또는) 치료 방법 |
| US20040151772A1 (en) | 2002-11-08 | 2004-08-05 | Egalet A/S | Controlled release carvedilol compositions |
| US8877241B2 (en) | 2003-03-26 | 2014-11-04 | Egalet Ltd. | Morphine controlled release system |
| EP1615888A1 (en) * | 2003-04-21 | 2006-01-18 | Matrix Laboratories Ltd | Process for the preparation of carvedilol form-ii |
| SI21616A (sl) * | 2003-09-02 | 2005-04-30 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Nove kristalne oblike karvedilola |
| US7750036B2 (en) | 2003-11-25 | 2010-07-06 | Sb Pharmco Puerto Rico Inc. | Carvedilol salts, corresponding compositions, methods of delivery and/or treatment |
| WO2006061364A1 (en) * | 2004-12-09 | 2006-06-15 | Zach System S.P.A. | Process for the preparation of carvedilol and its enantiomers |
| KR20070088507A (ko) * | 2005-06-09 | 2007-08-29 | 테바 파마슈티컬 인더스트리즈 리미티드 | 카베딜올의 결정질 형태 및 이것의 제조 방법 |
| WO2008002683A2 (en) | 2006-06-28 | 2008-01-03 | Teva Pharmaceutical Industries Ltd. | Polymorphous forms of carvedilol phosphate |
| US20080249317A1 (en) * | 2007-04-04 | 2008-10-09 | Apotex Inc. | Novel amorphous form of carvedilol phosphate and processes for the preparation thereof |
| EP2155167A2 (en) | 2007-06-04 | 2010-02-24 | Egalet A/S | Controlled release pharmaceutical compositions for prolonged effect |
| CA2751667C (en) | 2009-02-06 | 2016-12-13 | Egalet Ltd. | Immediate release composition resistant to abuse by intake of alcohol |
| EP2445487A2 (en) | 2009-06-24 | 2012-05-02 | Egalet Ltd. | Controlled release formulations |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2815926A1 (de) * | 1978-04-13 | 1979-10-18 | Boehringer Mannheim Gmbh | Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3319027A1 (de) * | 1983-05-26 | 1984-11-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten |
-
1997
- 1997-07-22 EP EP97112491A patent/EP0893440A1/en not_active Withdrawn
-
1998
- 1998-07-15 PE PE1998000626A patent/PE96999A1/es not_active Application Discontinuation
- 1998-07-15 MY MYPI98003245A patent/MY117734A/en unknown
- 1998-07-18 SI SI9830442T patent/SI1000027T1/xx unknown
- 1998-07-18 PL PL338432A patent/PL191602B1/pl unknown
- 1998-07-18 YU YU2200A patent/YU2200A/sh unknown
- 1998-07-18 PT PT98937576T patent/PT1000027E/pt unknown
- 1998-07-18 DK DK98937576T patent/DK1000027T3/da active
- 1998-07-18 TR TR2000/00148T patent/TR200000148T2/xx unknown
- 1998-07-18 AU AU86319/98A patent/AU740453B2/en not_active Ceased
- 1998-07-18 ES ES98937576T patent/ES2195366T3/es not_active Expired - Lifetime
- 1998-07-18 AT AT98937576T patent/ATE236123T1/de not_active IP Right Cessation
- 1998-07-18 JP JP2000504104A patent/JP2001510824A/ja active Pending
- 1998-07-18 CN CN98807436A patent/CN1125047C/zh not_active Expired - Fee Related
- 1998-07-18 NZ NZ502136A patent/NZ502136A/en unknown
- 1998-07-18 DE DE69812964T patent/DE69812964T2/de not_active Expired - Fee Related
- 1998-07-18 IL IL13367798A patent/IL133677A/en not_active IP Right Cessation
- 1998-07-18 BR BR9810776-3A patent/BR9810776A/pt not_active Application Discontinuation
- 1998-07-18 RU RU2000103033/04A patent/RU2202542C2/ru not_active IP Right Cessation
- 1998-07-18 KR KR1020007000667A patent/KR100336229B1/ko not_active IP Right Cessation
- 1998-07-18 TW TW087111738A patent/TW505631B/zh not_active IP Right Cessation
- 1998-07-18 HU HU0003198A patent/HUP0003198A3/hu unknown
- 1998-07-18 CA CA002296637A patent/CA2296637C/en not_active Expired - Fee Related
- 1998-07-18 CZ CZ20000221A patent/CZ296947B6/cs not_active IP Right Cessation
- 1998-07-18 EP EP98937576A patent/EP1000027B1/en not_active Expired - Lifetime
- 1998-07-18 WO PCT/EP1998/004475 patent/WO1999005105A1/en active IP Right Grant
- 1998-07-20 MA MA25178A patent/MA26523A1/fr unknown
- 1998-07-21 ZA ZA9806475A patent/ZA986475B/xx unknown
- 1998-07-21 AR ARP980103547A patent/AR015133A1/es unknown
- 1998-07-22 HR HR97112491.2A patent/HRP980406A2/hr not_active Application Discontinuation
- 1998-07-22 UY UY25108A patent/UY25108A1/es not_active IP Right Cessation
-
2000
- 2000-01-21 NO NO20000301A patent/NO313588B1/no unknown
-
2001
- 2001-01-02 HK HK01100012A patent/HK1029339A1/xx not_active IP Right Cessation
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