NZ575652A - Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators - Google Patents

Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators

Info

Publication number
NZ575652A
NZ575652A NZ575652A NZ57565207A NZ575652A NZ 575652 A NZ575652 A NZ 575652A NZ 575652 A NZ575652 A NZ 575652A NZ 57565207 A NZ57565207 A NZ 57565207A NZ 575652 A NZ575652 A NZ 575652A
Authority
NZ
New Zealand
Prior art keywords
alkyl
dihydro
isoquinolin
dimethylbutanamide
compound
Prior art date
Application number
NZ575652A
Other languages
English (en)
Inventor
Jean-Michel Vernier
La Rosa Martha Alicia De
Huanming Chen
Jim Zhen Wu
Gary Lee Larson
Ian Wayne Cheney
Original Assignee
Valeant Pharmaceuticals Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valeant Pharmaceuticals Int filed Critical Valeant Pharmaceuticals Int
Publication of NZ575652A publication Critical patent/NZ575652A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
NZ575652A 2006-08-23 2007-08-22 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators NZ575652A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83994106P 2006-08-23 2006-08-23
PCT/US2007/018571 WO2008024398A2 (en) 2006-08-23 2007-08-22 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators

Publications (1)

Publication Number Publication Date
NZ575652A true NZ575652A (en) 2011-08-26

Family

ID=39107384

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ575652A NZ575652A (en) 2006-08-23 2007-08-22 Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators

Country Status (23)

Country Link
US (1) US8293911B2 (enExample)
EP (1) EP2061465B1 (enExample)
JP (1) JP5419691B2 (enExample)
KR (1) KR20090079191A (enExample)
CN (1) CN101563085A (enExample)
AR (1) AR062508A1 (enExample)
AU (1) AU2007288253B2 (enExample)
BR (1) BRPI0716715B1 (enExample)
CA (1) CA2661462C (enExample)
CL (1) CL2007002455A1 (enExample)
DK (1) DK2061465T3 (enExample)
ES (1) ES2420960T3 (enExample)
IL (1) IL197161A (enExample)
MX (1) MX2009002002A (enExample)
NO (1) NO343575B1 (enExample)
NZ (1) NZ575652A (enExample)
PL (1) PL2061465T3 (enExample)
PT (1) PT2061465E (enExample)
RU (1) RU2009110172A (enExample)
SG (1) SG174095A1 (enExample)
TW (1) TW200827339A (enExample)
WO (1) WO2008024398A2 (enExample)
ZA (1) ZA200901977B (enExample)

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US20080045534A1 (en) * 2006-08-18 2008-02-21 Valeant Pharmaceuticals North America Derivatives of 1,3-diamino benzene as potassium channel modulators
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US8367684B2 (en) 2007-06-13 2013-02-05 Valeant Pharmaceuticals International Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators
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ES2420960T3 (es) 2013-08-28
AR062508A1 (es) 2008-11-12
SG174095A1 (en) 2011-09-29
DK2061465T3 (da) 2013-07-08
TW200827339A (en) 2008-07-01
EP2061465A2 (en) 2009-05-27
WO2008024398A2 (en) 2008-02-28
BRPI0716715B1 (pt) 2021-07-06
PL2061465T3 (pl) 2014-03-31
WO2008024398B1 (en) 2008-08-14
CL2007002455A1 (es) 2008-04-18
ZA200901977B (en) 2010-02-24
EP2061465B1 (en) 2013-04-10
PT2061465E (pt) 2013-07-15
AU2007288253A1 (en) 2008-02-28
NO20091183L (no) 2009-05-08
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JP5419691B2 (ja) 2014-02-19
BRPI0716715A2 (pt) 2013-09-03
IL197161A (en) 2015-07-30
NO343575B1 (no) 2019-04-08
CN101563085A (zh) 2009-10-21
CA2661462C (en) 2015-09-29
KR20090079191A (ko) 2009-07-21
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US20080139610A1 (en) 2008-06-12
AU2007288253B2 (en) 2013-05-02
CA2661462A1 (en) 2008-02-28
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RU2009110172A (ru) 2010-09-27
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US8293911B2 (en) 2012-10-23

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