NO20091183L - Derivater av 4-(N-azacykloalkyl)-anilider, fremgangsmåte for fremstilling av slike forbindelser, preparater omfattende slike forbindelser samt anvendelse av slike forbindelser for forhindring eller behandling av sykdom - Google Patents
Derivater av 4-(N-azacykloalkyl)-anilider, fremgangsmåte for fremstilling av slike forbindelser, preparater omfattende slike forbindelser samt anvendelse av slike forbindelser for forhindring eller behandling av sykdomInfo
- Publication number
- NO20091183L NO20091183L NO20091183A NO20091183A NO20091183L NO 20091183 L NO20091183 L NO 20091183L NO 20091183 A NO20091183 A NO 20091183A NO 20091183 A NO20091183 A NO 20091183A NO 20091183 L NO20091183 L NO 20091183L
- Authority
- NO
- Norway
- Prior art keywords
- compounds
- azacycloalkyl
- anilides
- disease
- prevention
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
- C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US83994106P | 2006-08-23 | 2006-08-23 | |
PCT/US2007/018571 WO2008024398A2 (en) | 2006-08-23 | 2007-08-22 | Derivatives of 4-(n-azacycloalkyl) anilides as potassium channel modulators |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20091183L true NO20091183L (no) | 2009-05-08 |
NO343575B1 NO343575B1 (no) | 2019-04-08 |
Family
ID=39107384
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20091183A NO343575B1 (no) | 2006-08-23 | 2009-03-20 | Derivater av 4-(N-azacykloalkyl)-anilider, fremgangsmåte for fremstilling av slike forbindelser, preparater omfattende slike forbindelser samt anvendelse av slike forbindelser for forhindring eller behandling av sykdom |
Country Status (23)
Country | Link |
---|---|
US (1) | US8293911B2 (no) |
EP (1) | EP2061465B1 (no) |
JP (1) | JP5419691B2 (no) |
KR (1) | KR20090079191A (no) |
CN (1) | CN101563085A (no) |
AR (1) | AR062508A1 (no) |
AU (1) | AU2007288253B2 (no) |
BR (1) | BRPI0716715B1 (no) |
CA (1) | CA2661462C (no) |
CL (1) | CL2007002455A1 (no) |
DK (1) | DK2061465T3 (no) |
ES (1) | ES2420960T3 (no) |
IL (1) | IL197161A (no) |
MX (1) | MX2009002002A (no) |
NO (1) | NO343575B1 (no) |
NZ (1) | NZ575652A (no) |
PL (1) | PL2061465T3 (no) |
PT (1) | PT2061465E (no) |
RU (1) | RU2009110172A (no) |
SG (1) | SG174095A1 (no) |
TW (1) | TW200827339A (no) |
WO (1) | WO2008024398A2 (no) |
ZA (1) | ZA200901977B (no) |
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US20050089559A1 (en) * | 2003-10-23 | 2005-04-28 | Istvan Szelenyi | Combinations of potassium channel openers and sodium channel inhibitors or sodium channel-influencing active compounds for treating pains |
KR101412339B1 (ko) | 2004-07-15 | 2014-06-25 | 알바니 몰레큘라 리써치, 인크. | 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를차단하기 위한 용도 |
US7960436B2 (en) | 2006-06-05 | 2011-06-14 | Valeant Pharmaceuticals International | Substituted arylamino-1,2,3,4-tetrahydro naphthalenes and-2,3-dihydro-1H-indenes as potassium channel modulators |
US20080045534A1 (en) * | 2006-08-18 | 2008-02-21 | Valeant Pharmaceuticals North America | Derivatives of 1,3-diamino benzene as potassium channel modulators |
MX2009002002A (es) | 2006-08-23 | 2009-07-22 | Valeant Pharmaceuticals Int | Derivados de 4-(n-azacicloalquil) anilidas como moduladores de canal de potasio. |
US8993593B2 (en) * | 2006-08-23 | 2015-03-31 | Valeant Pharmaceuticals International | N-(4-(6-fluoro-3,4-dihydroisoquinolin-2(1H)-yl)-2,6-dimethylphenyl)-3,3-dimethylbutanamide as potassium channel modulators |
US8722929B2 (en) * | 2006-10-10 | 2014-05-13 | Valeant Pharmaceuticals International | N-[2-amino-4-(phenylmethoxy)phenyl] amides and related compounds as potassium channel modulators |
KR20090083479A (ko) | 2006-11-28 | 2009-08-03 | 밸리언트 파마슈티컬즈 인터내셔널 | 칼륨 채널 조절제로서의 1,4 디아미노 이환 레티가빈 유사체 |
US8367684B2 (en) * | 2007-06-13 | 2013-02-05 | Valeant Pharmaceuticals International | Derivatives of 4-(N-azacycloalkyl) anilides as potassium channel modulators |
US8563566B2 (en) * | 2007-08-01 | 2013-10-22 | Valeant Pharmaceuticals International | Naphthyridine derivatives as potassium channel modulators |
US7786146B2 (en) | 2007-08-13 | 2010-08-31 | Valeant Pharmaceuticals International | Derivatives of 5-amino-4,6-disubstituted indole and 5-amino-4,6-disubstituted indoline as potassium channel modulators |
US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
EP2310369A4 (en) | 2008-06-24 | 2014-02-19 | Valeant Pharmaceuticals Int | BENZYL OXYANILID DERIVATIVES SUITABLE AS SODIUM CHANNEL MODULATORS |
TW201041857A (en) * | 2009-05-11 | 2010-12-01 | Lundbeck & Co As H | Stable forms of N-(2,6-dimethyl-4-morpholin-4-yl-phenyl)-3,3-dimethyl-butyramide |
CN102595902B (zh) | 2009-05-12 | 2015-04-29 | 阿尔巴尼分子研究公司 | 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途 |
ES2528404T3 (es) | 2009-05-12 | 2015-02-10 | Bristol-Myers Squibb Company | Formas cristalinas de (S)-7-([1,2,4]triazol[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina y sus usos |
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BRPI0716715B1 (pt) | 2021-07-06 |
CL2007002455A1 (es) | 2008-04-18 |
AU2007288253B2 (en) | 2013-05-02 |
US20080139610A1 (en) | 2008-06-12 |
EP2061465A2 (en) | 2009-05-27 |
ZA200901977B (en) | 2010-02-24 |
DK2061465T3 (da) | 2013-07-08 |
MX2009002002A (es) | 2009-07-22 |
RU2009110172A (ru) | 2010-09-27 |
EP2061465B1 (en) | 2013-04-10 |
NZ575652A (en) | 2011-08-26 |
JP5419691B2 (ja) | 2014-02-19 |
PT2061465E (pt) | 2013-07-15 |
US8293911B2 (en) | 2012-10-23 |
WO2008024398B1 (en) | 2008-08-14 |
CN101563085A (zh) | 2009-10-21 |
ES2420960T3 (es) | 2013-08-28 |
AU2007288253A1 (en) | 2008-02-28 |
BRPI0716715A2 (pt) | 2013-09-03 |
AR062508A1 (es) | 2008-11-12 |
KR20090079191A (ko) | 2009-07-21 |
CA2661462A1 (en) | 2008-02-28 |
TW200827339A (en) | 2008-07-01 |
WO2008024398A3 (en) | 2008-06-26 |
JP2010501568A (ja) | 2010-01-21 |
CA2661462C (en) | 2015-09-29 |
PL2061465T3 (pl) | 2014-03-31 |
SG174095A1 (en) | 2011-09-29 |
IL197161A (en) | 2015-07-30 |
IL197161A0 (en) | 2009-12-24 |
NO343575B1 (no) | 2019-04-08 |
EP2061465A4 (en) | 2011-03-16 |
WO2008024398A2 (en) | 2008-02-28 |
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