HK1166983A1 - 包含用於治療疾病或紊亂的化合物的固體形式，其組合物，及其用途 - Google Patents

包含用於治療疾病或紊亂的化合物的固體形式，其組合物，及其用途

Info

Publication number
HK1166983A1
HK1166983A1 HK12107742.2A HK12107742A HK1166983A1 HK 1166983 A1 HK1166983 A1 HK 1166983A1 HK 12107742 A HK12107742 A HK 12107742A HK 1166983 A1 HK1166983 A1 HK 1166983A1
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HK
Hong Kong
Prior art keywords
disorders
diseases
compositions
compounds
treatment
Prior art date
Application number
HK12107742.2A
Other languages
English (en)
Inventor
瑪麗．
．彼徹姆斯
路易絲．米歇爾．卡梅倫
羅伯特．希爾格拉夫
莫希特．阿塔爾．柯塔爾
馬諾哈爾．
．塞恩丹
珍．徐
Original Assignee
西格諾藥品有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 西格諾藥品有限公司 filed Critical 西格諾藥品有限公司
Publication of HK1166983A1 publication Critical patent/HK1166983A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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    • A—HUMAN NECESSITIES
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    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
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    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
HK12107742.2A 2006-10-27 2012-08-07 包含用於治療疾病或紊亂的化合物的固體形式，其組合物，及其用途 HK1166983A1 (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85475706P 2006-10-27 2006-10-27

Publications (1)

Publication Number Publication Date
HK1166983A1 true HK1166983A1 (zh) 2012-11-16

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ID=39149400

Family Applications (2)

Application Number Title Priority Date Filing Date
HK09110990.0A HK1131147A1 (en) 2006-10-27 2009-11-25 Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro- phenylamino)-9h-purin-2-ylamino]-cyclohexan-1-ol, compositions thereof, and use therewith
HK12107742.2A HK1166983A1 (zh) 2006-10-27 2012-08-07 包含用於治療疾病或紊亂的化合物的固體形式，其組合物，及其用途

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HK09110990.0A HK1131147A1 (en) 2006-10-27 2009-11-25 Solid forms comprising 4-[9-(tetrahydro-furan-3-yl)-8-(2,4,6-trifluoro- phenylamino)-9h-purin-2-ylamino]-cyclohexan-1-ol, compositions thereof, and use therewith

Country Status (17)

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US (2) US8158635B2 (zh)
EP (2) EP2615091B1 (zh)
JP (2) JP5523833B2 (zh)
KR (2) KR20090084891A (zh)
CN (2) CN101568544B (zh)
AU (1) AU2007318132B2 (zh)
BR (1) BRPI0717394A2 (zh)
CA (1) CA2667345C (zh)
ES (2) ES2442257T3 (zh)
HK (2) HK1131147A1 (zh)
IL (1) IL198227A (zh)
MX (1) MX2009003913A (zh)
NO (1) NO20092021L (zh)
NZ (3) NZ576347A (zh)
RU (2) RU2496780C2 (zh)
WO (1) WO2008057252A2 (zh)
ZA (1) ZA201007905B (zh)

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CN109069512B (zh) 2016-04-01 2022-06-14 西格诺药品有限公司 取代的氨基嘌呤化合物、其组合物以及相关治疗方法
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KR20200061363A (ko) 2017-10-04 2020-06-02 셀진 코포레이션 시스-4-[2-｛[(3ｓ,4ｒ)-3-플루오로옥산-4-일]아미노｝-8-(2,4,6-트리클로로아닐리노)-9ｈ-퓨린-9-일]-1-메틸사이클로헥산-1-카르복스아미드의 제조 공정
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IL198227A (en) 2015-07-30
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RU2009120026A (ru) 2010-12-10
AU2007318132A1 (en) 2008-05-15
CN102382113B (zh) 2016-04-06
JP2014058550A (ja) 2014-04-03
NZ589053A (en) 2012-03-30
MX2009003913A (es) 2009-04-24
EP2615091A3 (en) 2014-01-22
EP2615091A2 (en) 2013-07-17
ZA201007905B (en) 2012-06-29
US20090048275A1 (en) 2009-02-19
EP2076516A2 (en) 2009-07-08
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CA2667345C (en) 2016-03-22
RU2013134978A (ru) 2015-01-27
CN101568544B (zh) 2016-10-26
KR20090084891A (ko) 2009-08-05
NZ598071A (en) 2013-08-30
JP5523833B2 (ja) 2014-06-18
IL198227A0 (en) 2009-12-24
NO20092021L (no) 2009-07-27
CN102382113A (zh) 2012-03-21
AU2007318132B2 (en) 2012-11-08
US8158635B2 (en) 2012-04-17
CN101568544A (zh) 2009-10-28
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EP2076516B1 (en) 2013-12-11
US20120115890A1 (en) 2012-05-10
EP2615091B1 (en) 2016-01-20
RU2496780C2 (ru) 2013-10-27
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WO2008057252A3 (en) 2008-10-09
BRPI0717394A2 (pt) 2013-10-15

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