NO974911L - Fremstilling og anvendelse av sulfaterte oligosakarider - Google Patents
Fremstilling og anvendelse av sulfaterte oligosakariderInfo
- Publication number
- NO974911L NO974911L NO974911A NO974911A NO974911L NO 974911 L NO974911 L NO 974911L NO 974911 A NO974911 A NO 974911A NO 974911 A NO974911 A NO 974911A NO 974911 L NO974911 L NO 974911L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- sulfated oligosaccharides
- rog
- monosaccharide
- sulfated
- Prior art date
Links
- 229920001542 oligosaccharide Polymers 0.000 title abstract 2
- 150000002482 oligosaccharides Chemical class 0.000 title abstract 2
- 125000001483 monosaccharide substituent group Chemical group 0.000 abstract 2
- 239000004037 angiogenesis inhibitor Substances 0.000 abstract 1
- 230000001772 anti-angiogenic effect Effects 0.000 abstract 1
- 229940121363 anti-inflammatory agent Drugs 0.000 abstract 1
- 239000002260 anti-inflammatory agent Substances 0.000 abstract 1
- 230000002001 anti-metastasis Effects 0.000 abstract 1
- 239000002257 antimetastatic agent Substances 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H11/00—Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0024—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid beta-D-Glucans; (beta-1,3)-D-Glucans, e.g. paramylon, coriolan, sclerotan, pachyman, callose, scleroglucan, schizophyllan, laminaran, lentinan or curdlan; (beta-1,6)-D-Glucans, e.g. pustulan; (beta-1,4)-D-Glucans; (beta-1,3)(beta-1,4)-D-Glucans, e.g. lichenan; Derivatives thereof
- C08B37/0027—2-Acetamido-2-deoxy-beta-glucans; Derivatives thereof
- C08B37/003—Chitin, i.e. 2-acetamido-2-deoxy-(beta-1,4)-D-glucan or N-acetyl-beta-1,4-D-glucosamine; Chitosan, i.e. deacetylated product of chitin or (beta-1,4)-D-glucosamine; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Materials Engineering (AREA)
- Polymers & Plastics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Emergency Medicine (AREA)
- Ophthalmology & Optometry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Hospice & Palliative Care (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPN2618A AUPN261895A0 (en) | 1995-04-28 | 1995-04-28 | Preparation and use of sulfated oligosaccharides |
PCT/AU1996/000238 WO1996033726A1 (en) | 1995-04-28 | 1996-04-24 | Preparation and use of sulfated oligosaccharides |
Publications (2)
Publication Number | Publication Date |
---|---|
NO974911D0 NO974911D0 (no) | 1997-10-24 |
NO974911L true NO974911L (no) | 1997-12-29 |
Family
ID=3786969
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO974911A NO974911L (no) | 1995-04-28 | 1997-10-24 | Fremstilling og anvendelse av sulfaterte oligosakarider |
Country Status (26)
Country | Link |
---|---|
US (1) | US6143730A (is) |
EP (1) | EP0837683B1 (is) |
JP (2) | JP4514240B2 (is) |
KR (1) | KR100591960B1 (is) |
CN (1) | CN1090021C (is) |
AT (1) | ATE463250T1 (is) |
AU (1) | AUPN261895A0 (is) |
BR (1) | BR9608041B8 (is) |
CA (1) | CA2218872C (is) |
CZ (1) | CZ341097A3 (is) |
DE (1) | DE69638158D1 (is) |
EA (1) | EA001199B1 (is) |
EE (1) | EE9700277A (is) |
ES (1) | ES2341924T3 (is) |
FI (1) | FI974060A0 (is) |
HU (1) | HUP9802394A2 (is) |
IL (1) | IL118047A (is) |
IS (1) | IS4596A (is) |
NO (1) | NO974911L (is) |
NZ (1) | NZ305815A (is) |
PL (1) | PL184357B1 (is) |
PT (1) | PT837683E (is) |
TR (1) | TR199701264T1 (is) |
TW (1) | TW446710B (is) |
WO (1) | WO1996033726A1 (is) |
ZA (1) | ZA963339B (is) |
Families Citing this family (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPO556297A0 (en) * | 1997-03-11 | 1997-04-10 | Australian National University, The | Sulfated oligosaccharides having anticoagulant/ antithrombotic activity |
WO1999009999A1 (en) * | 1997-08-28 | 1999-03-04 | University Of Washington | Specific saccharide compositions and methods for treating alzheimer's disease and other amyloidoses |
AUPO888497A0 (en) * | 1997-09-01 | 1997-09-25 | Australian National University, The | Use of sulfated oligosaccharides as inhibitors of cardiovascular disease |
AUPO976897A0 (en) * | 1997-10-14 | 1997-11-06 | Australian National University, The | Use of sulfated oligosaccharides in lowering blood triglyceride levels |
GB9802725D0 (en) | 1998-02-09 | 1998-04-08 | Ciba Geigy Ag | Organic compounds |
US7132402B2 (en) * | 1998-11-24 | 2006-11-07 | Wyeth | Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation |
US7081448B2 (en) * | 1998-11-24 | 2006-07-25 | Wyeth | Benzyllactobionamides as inhibitors of smooth muscle cell proliferation |
US20040220103A1 (en) * | 1999-04-19 | 2004-11-04 | Immunex Corporation | Soluble tumor necrosis factor receptor treatment of medical disorders |
US6083933A (en) * | 1999-04-19 | 2000-07-04 | Stellar International Inc. | Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution |
GB0001481D0 (en) * | 2000-01-21 | 2000-03-15 | Theryte Ltd | System for delivering a medicament |
GB0003048D0 (en) * | 2000-02-11 | 2000-03-29 | Dealler Stephen F | The therapeutic use of polysulphonated polyglycosides or other polyanionic compounds in autism |
FR2808687B1 (fr) * | 2000-04-27 | 2003-12-05 | Goemar Lab Sa | Medicament contenant des substances polysaccharidiques pour l'activation de l'apoptose |
JP4676048B2 (ja) * | 2000-07-10 | 2011-04-27 | 生化学工業株式会社 | 脱髄性疾患処置剤 |
US7407773B2 (en) * | 2000-11-03 | 2008-08-05 | Procognia, Ltd. | Method for characterizing a carbohydrate polymer |
TW519716B (en) * | 2000-12-19 | 2003-02-01 | Tokyo Electron Ltd | Wafer bias drive for a plasma source |
CA2435637A1 (en) * | 2001-01-23 | 2002-08-01 | Massachusetts Institute Of Technology | Solid- and solution -phase synthesis of heparin and other glycosaminoglycans |
CN1394867A (zh) * | 2001-07-06 | 2003-02-05 | 中国科学院生态环境研究中心 | 可作药物的寡糖和其制备方法及含该寡糖的药物组合物 |
CA2457719C (en) | 2001-09-12 | 2012-01-03 | Benito Casu | Derivatives of partially desulphated glycosaminoglycans as heparanase inhibitors, endowed with antiangiogenic activity and devoid of anticoagulating effect |
KR20030046810A (ko) * | 2001-12-06 | 2003-06-18 | 은삼제약 주식회사 | 콘드로이친 황산의 분해산물을 포함하는 관절염 예방 또는치료용 약학적 조성물 |
AUPS052802A0 (en) * | 2002-02-15 | 2002-03-07 | Praxis Pharmaceuticals International Pty Ltd | Carbohydrate-based anti-wrinkle and tissue remodelling compounds |
AU2003225724A1 (en) * | 2002-03-11 | 2003-09-29 | Momenta Pharmaceuticals, Inc. | Analysis of sulfated polysaccharides |
US20040161476A1 (en) * | 2003-02-19 | 2004-08-19 | Hahn Sungtack Samuel | Cystitis treatment with high dose chondroitin sulfate |
WO2005054493A2 (en) * | 2003-06-12 | 2005-06-16 | Mayo Foundation For Medical Education And Research | Altered activity of toll-like receptors |
RU2392281C2 (ru) * | 2004-03-04 | 2010-06-20 | Проджен Фармасьютикалз Лимитед | Сульфатированные производные олигосахаридов |
EP2086553A4 (en) * | 2006-10-20 | 2010-12-29 | Univ Australian | INHIBITION OF EXTRACELLULAR MATRIX DEGRADATION |
US9139876B1 (en) | 2007-05-03 | 2015-09-22 | Momenta Pharmacueticals, Inc. | Method of analyzing a preparation of a low molecular weight heparin |
NZ601148A (en) * | 2007-05-31 | 2012-08-31 | Glycan Biosciences | Use of pentosan polysulfate for treatment or prophylaxis of allergic rhinitis |
FR2917971B1 (fr) | 2007-06-28 | 2009-10-23 | Engelhard Lyon Soc Par Actions | Composition amincissante |
US8153611B2 (en) * | 2007-06-28 | 2012-04-10 | Basf Beauty Care Solutions France S.A.S. | Use of sulfated oligosaccharides as slimming cosmetic ingredients |
WO2009000935A1 (en) * | 2007-06-28 | 2008-12-31 | Basf Beauty Care Solutions France Sas | Slimming composition |
KR101646960B1 (ko) | 2007-10-16 | 2016-08-09 | 프로젠 피지500 시리즈 피티와이 리미티드 | 신규한 황산화된 올리고사카라이드 유도체 |
WO2009078015A2 (en) * | 2007-12-18 | 2009-06-25 | Procognia (Israel) Ltd | Method and assay for glycosylation pattern detection related to cell state of stem cells |
CA2724910C (en) * | 2008-05-30 | 2015-09-01 | Momenta Pharmaceuticals, Inc. | Saccharide structures and methods of making and using such structures |
EP2149580A1 (en) | 2008-07-15 | 2010-02-03 | Istituto Scientifico di Chimica E Biochimica "G Ronzoni | Mimetics of sulfated oligosaccharides |
US8592140B2 (en) | 2009-01-02 | 2013-11-26 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
US8232073B2 (en) | 2009-01-02 | 2012-07-31 | Zacharon Pharmaceuticals, Inc. | Quantification of non-reducing end glycan residual compounds |
US9029530B2 (en) | 2009-01-02 | 2015-05-12 | Biomarin Pharmaceutical Inc. | Detection of oligosaccharides |
US8809009B2 (en) | 2009-01-02 | 2014-08-19 | Biomarin Pharmaceutical Inc. | Methods of diagnosing a disease and methods of monitoring treatment of a disease by quantifying a non-reducing end glycan residual compound and comparing to a second biomarker |
GB0915315D0 (en) | 2009-09-03 | 2009-10-07 | Univ Manchester | Use of non-digestible oligosaccharides |
JP5701498B2 (ja) * | 2009-12-01 | 2015-04-15 | 公益財団法人微生物化学研究会 | 炎症性細胞からのヘパラナーゼの放出抑制剤、抗炎症剤、及び薬用組成物 |
ES2817779T3 (es) * | 2010-01-19 | 2021-04-08 | Momenta Pharmaceuticals Inc | Evaluación de preparaciones de heparina |
JPWO2011122321A1 (ja) * | 2010-03-29 | 2013-07-08 | 国立大学法人名古屋大学 | ヘパリン結合性蛋白に対する生理活性阻害剤 |
BR112013013544B1 (pt) * | 2010-12-01 | 2020-09-29 | The Australian National University | Uso de um oligossacarídeo polianiônico na fabricação de um medicamento para o tratamento de sepse |
US9744188B2 (en) * | 2011-02-18 | 2017-08-29 | President And Fellows Of Harvard College | Methods of promoting neuronal outgrowth by gypican 2 that binds to receptor protein tyrosine phosphatase sigma |
WO2012115952A1 (en) | 2011-02-21 | 2012-08-30 | Momenta Pharmaceuticals, Inc. | Evaluating heparin preparations |
CN102199175A (zh) * | 2011-04-07 | 2011-09-28 | 福州大学 | 硫酸类肝素二糖的制备纯化方法及其纯化产品 |
CN103547270A (zh) * | 2011-06-09 | 2014-01-29 | 基亚生物科技股份有限公司 | 用于抑制肝癌复发、恶化或转移之医药组成物 |
ES2699238T3 (es) * | 2012-01-30 | 2019-02-08 | Baxalta GmbH | Polisacáridos sulfatados o sulfonatados no anticoagulantes |
BR112015028710A2 (pt) * | 2013-05-16 | 2017-09-19 | Agency Science Tech & Res | Sulfato de heparan hs8 isolado ou substancialmente purificado, composição farmacêutica ou medicamento, implante biocompatível ou prótese, método de formação de um implante ou prótese biocompatível, método de cultivo de células-tronco, método de enriquecimento para unidades formadoras de colônias, meio de cultura, kit de peças, produtos e método para aumentar a estabilidade de um fator de crescimento |
EP3502119A3 (en) | 2014-05-08 | 2019-10-02 | Immunexcite, Inc. | Immunomodulating beta-1,6-d-glucans |
SE538503C2 (en) * | 2014-11-11 | 2016-08-16 | Tx Medic Ab | New dextran sulfate |
CZ306662B6 (cs) * | 2015-06-26 | 2017-04-26 | Contipro A.S. | Deriváty sulfatovaných polysacharidů, způsob jejich přípravy, způsob jejich modifikace a použití |
CN105504097B (zh) * | 2015-12-30 | 2018-07-03 | 深圳市海普瑞药业集团股份有限公司 | 一种硫酸化肝素寡糖及其制备方法和应用 |
JP2016199579A (ja) * | 2016-07-08 | 2016-12-01 | 基亜生物科技股▲ふん▼有限公司Medigen Biotechnology Corp. | 肝癌の再発、悪化または転移の抑制に用いる医薬組成物 |
AU2017376817B2 (en) | 2016-12-13 | 2022-03-31 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
US11787783B2 (en) | 2016-12-13 | 2023-10-17 | Beta Therapeutics Pty Ltd | Heparanase inhibitors and use thereof |
TWI689309B (zh) * | 2017-12-12 | 2020-04-01 | 中央研究院 | 八醣及其用途 |
WO2019113646A1 (en) * | 2017-12-15 | 2019-06-20 | Griffith University | Sulfation method |
JP6619830B2 (ja) * | 2018-02-22 | 2019-12-11 | 基亜生物科技股▲ふん▼有限公司Medigen Biotechnology Corp. | 肝癌の再発、悪化または転移の抑制に用いる医薬組成物 |
NL2024493B1 (en) * | 2019-12-16 | 2021-09-02 | Logick Energetics B V | Pharmaceutical composition for preventing or stopping metastases |
CN114828846A (zh) | 2019-12-18 | 2022-07-29 | 罗吉科能量有限公司 | 用于预防或阻止转移的医药组合物 |
CN110917208B (zh) * | 2019-12-27 | 2021-02-12 | 浙江医院 | 硫酸化甘露葡萄糖醛酸六糖在防治动脉粥样硬化中的应用 |
CN111904968A (zh) * | 2020-08-21 | 2020-11-10 | 青岛市中心医院 | 硫酸半乳四糖及其衍生物在制备抗上皮细胞黏附药物中的应用 |
CN114134188B (zh) * | 2021-07-23 | 2023-03-17 | 光明乳业股份有限公司 | 一种发酵小麦麸皮合成胞外多糖的方法 |
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---|---|---|---|---|
ZA869530B (en) * | 1985-12-24 | 1987-10-28 | Marion Laboratories Inc | Use of synthetic sulfated saccharides to enhance wound healing |
FR2597484B1 (fr) * | 1986-04-17 | 1988-12-23 | Sanofi Sa | Glycosaminoglycanes de type heparine ou heparane-sulfate dotes d'une activite sur la division et la differentiation cellulaires, leur preparation et leurs applications therapeutiques. |
US5541166A (en) * | 1987-01-23 | 1996-07-30 | The Australian National University | Sulphated polysaccharides having anti-metastatic and/or anti-inflammatory activity |
EP0338092A1 (en) * | 1987-10-30 | 1989-10-25 | Chugai Seiyaku Kabushiki Kaisha | Anti-hiv agent |
US5506210A (en) * | 1988-08-19 | 1996-04-09 | The Australian National University | Phosphosugar-based anti-inflammatory and/or immunosuppressive drugs |
JPH0296588A (ja) * | 1988-09-29 | 1990-04-09 | Rikagaku Kenkyusho | 硫酸化オリゴ糖及びその関連物質 |
JP2956090B2 (ja) * | 1989-10-30 | 1999-10-04 | 大日本インキ化学工業株式会社 | オリゴ糖誘導体 |
CA2071915A1 (en) * | 1990-08-23 | 1992-02-24 | Tadao Shoji | Antiviral agent |
CA2061370A1 (en) * | 1991-03-13 | 1992-09-14 | Markus Hosang | Pharmaceutical preparations |
EP0582665A1 (en) * | 1991-04-17 | 1994-02-16 | Glycomed Incorporated | Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation |
JPH06256373A (ja) * | 1993-01-11 | 1994-09-13 | Dainippon Ink & Chem Inc | 硫酸化オリゴ糖配糖体アシル化物およびこれを有効成分とする抗ウイルス剤 |
US5459257A (en) * | 1993-01-11 | 1995-10-17 | Dainippon Ink And Chemicals, Inc. | Sulfated oligoglycoside acylate and antiviral agent containing the same as active ingredient |
FR2710741B1 (fr) * | 1993-09-30 | 1995-10-27 | Commissariat Energie Atomique | Capteur électronique destiné à la caractérisation de grandeurs physiques et procédé de réalisation d'un tel capteur. |
US5739115A (en) * | 1993-10-07 | 1998-04-14 | Glycomed Incorporated | Sulfated maltooligosaccharides with heparin-like properties |
CA2171465A1 (en) * | 1993-10-07 | 1995-04-13 | Peter Fugedi | Highly sulfated maltooligosaccharides with heparin-like properties |
-
1995
- 1995-04-28 AU AUPN2618A patent/AUPN261895A0/en not_active Abandoned
-
1996
- 1996-04-24 AT AT96910861T patent/ATE463250T1/de not_active IP Right Cessation
- 1996-04-24 PT PT96910861T patent/PT837683E/pt unknown
- 1996-04-24 CA CA002218872A patent/CA2218872C/en not_active Expired - Lifetime
- 1996-04-24 PL PL96323080A patent/PL184357B1/pl unknown
- 1996-04-24 KR KR1019970707723A patent/KR100591960B1/ko not_active IP Right Cessation
- 1996-04-24 HU HU9802394A patent/HUP9802394A2/hu unknown
- 1996-04-24 DE DE69638158T patent/DE69638158D1/de not_active Expired - Lifetime
- 1996-04-24 NZ NZ305815A patent/NZ305815A/xx not_active IP Right Cessation
- 1996-04-24 EE EE9700277A patent/EE9700277A/xx unknown
- 1996-04-24 ES ES96910861T patent/ES2341924T3/es not_active Expired - Lifetime
- 1996-04-24 EP EP96910861A patent/EP0837683B1/en not_active Expired - Lifetime
- 1996-04-24 JP JP53203896A patent/JP4514240B2/ja not_active Expired - Lifetime
- 1996-04-24 CZ CZ973410A patent/CZ341097A3/cs unknown
- 1996-04-24 TR TR97/01264T patent/TR199701264T1/xx unknown
- 1996-04-24 US US08/945,937 patent/US6143730A/en not_active Expired - Lifetime
- 1996-04-24 WO PCT/AU1996/000238 patent/WO1996033726A1/en not_active Application Discontinuation
- 1996-04-24 CN CN96193563A patent/CN1090021C/zh not_active Expired - Lifetime
- 1996-04-24 BR BRPI9608041-8B8A patent/BR9608041B8/pt not_active IP Right Cessation
- 1996-04-24 EA EA199700347A patent/EA001199B1/ru not_active IP Right Cessation
- 1996-04-25 TW TW085104940A patent/TW446710B/zh not_active IP Right Cessation
- 1996-04-26 IL IL11804796A patent/IL118047A/xx not_active IP Right Cessation
- 1996-04-26 ZA ZA963339A patent/ZA963339B/xx unknown
-
1997
- 1997-10-21 IS IS4596A patent/IS4596A/is unknown
- 1997-10-24 NO NO974911A patent/NO974911L/no not_active Application Discontinuation
- 1997-10-27 FI FI974060A patent/FI974060A0/fi unknown
-
2009
- 2009-06-09 JP JP2009138310A patent/JP2009235085A/ja not_active Withdrawn
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