NO332701B1 - Anvendelse av bisyklisk forbindelse til fremstilling av avforingspreparat - Google Patents

Anvendelse av bisyklisk forbindelse til fremstilling av avforingspreparat Download PDF

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Publication number
NO332701B1
NO332701B1 NO20030996A NO20030996A NO332701B1 NO 332701 B1 NO332701 B1 NO 332701B1 NO 20030996 A NO20030996 A NO 20030996A NO 20030996 A NO20030996 A NO 20030996A NO 332701 B1 NO332701 B1 NO 332701B1
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NO
Norway
Prior art keywords
preparation
bicyclic
formula
compound
fatty acid
Prior art date
Application number
NO20030996A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030996D0 (no
NO20030996L (no
Inventor
Ryuji Ueno
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24630250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO332701(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Publication of NO20030996D0 publication Critical patent/NO20030996D0/no
Publication of NO20030996L publication Critical patent/NO20030996L/no
Publication of NO332701B1 publication Critical patent/NO332701B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/559Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing hetero atoms other than oxygen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D221/00Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04Ortho- or peri-condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pyrane Compounds (AREA)
NO20030996A 2000-09-05 2003-03-04 Anvendelse av bisyklisk forbindelse til fremstilling av avforingspreparat NO332701B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/655,760 US6414016B1 (en) 2000-09-05 2000-09-05 Anti-constipation composition
PCT/JP2001/007628 WO2002020007A1 (en) 2000-09-05 2001-09-04 Cathartic composition

Publications (3)

Publication Number Publication Date
NO20030996D0 NO20030996D0 (no) 2003-03-04
NO20030996L NO20030996L (no) 2003-05-02
NO332701B1 true NO332701B1 (no) 2012-12-10

Family

ID=24630250

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030996A NO332701B1 (no) 2000-09-05 2003-03-04 Anvendelse av bisyklisk forbindelse til fremstilling av avforingspreparat

Country Status (25)

Country Link
US (7) US6414016B1 (cs)
EP (2) EP1315485B1 (cs)
JP (3) JP2004508327A (cs)
KR (2) KR100901102B1 (cs)
CN (1) CN100335049C (cs)
AR (2) AR030609A1 (cs)
AT (1) ATE476975T1 (cs)
AU (2) AU2001282615B2 (cs)
BR (1) BRPI0114042B8 (cs)
CA (1) CA2419741C (cs)
CZ (1) CZ304740B6 (cs)
DE (2) DE60131547T2 (cs)
DK (2) DK1857105T3 (cs)
ES (2) ES2296786T3 (cs)
HU (1) HU229319B1 (cs)
IL (2) IL154534A0 (cs)
MX (1) MXPA03001959A (cs)
NL (1) NL300757I2 (cs)
NO (1) NO332701B1 (cs)
NZ (1) NZ524401A (cs)
PT (2) PT1315485E (cs)
RU (1) RU2694361C3 (cs)
TW (1) TWI305147B (cs)
WO (1) WO2002020007A1 (cs)
ZA (1) ZA200301673B (cs)

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AU2003292556B2 (en) * 2002-12-27 2009-09-10 Sucampo Ag Derivatives of prostaglandins for treating abdominal discomfort
EP1641462B1 (en) * 2003-07-03 2010-11-24 Sucampo AG Enteric coated composition comprising prostaglandin analogs as chloride channel opener
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RU2392941C2 (ru) * 2004-09-02 2010-06-27 Сукампо Аг Производные простагландинов для лечения желудочно-кишечного нарушения
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CN103919783A (zh) 2005-03-04 2014-07-16 苏坎波公司 治疗外周血管病的方法和组合物
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
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WO2006109881A1 (en) * 2005-04-12 2006-10-19 Sucampo Ag Combined use of prostaglandin compound and proton pump inhibitor for the treatment of gastrointestinal disorders
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US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
CN101318948B (zh) * 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
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WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
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US9084815B2 (en) * 2009-09-16 2015-07-21 Sucampo Ag Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor
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US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
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Also Published As

Publication number Publication date
MXPA03001959A (es) 2003-06-24
US20120237598A1 (en) 2012-09-20
AU8261501A (en) 2002-03-22
NO20030996D0 (no) 2003-03-04
PT1315485E (pt) 2008-01-23
IL154534A (en) 2010-04-29
PT1857105E (pt) 2010-10-08
DK1315485T3 (da) 2008-03-03
AU2001282615B2 (en) 2006-06-22
CA2419741A1 (en) 2002-03-14
JP2009286806A (ja) 2009-12-10
WO2002020007A1 (en) 2002-03-14
CN1655776A (zh) 2005-08-17
ES2296786T3 (es) 2008-05-01
NZ524401A (en) 2004-08-27
DE60142810D1 (de) 2010-09-23
US20050222195A1 (en) 2005-10-06
US6610732B2 (en) 2003-08-26
KR100918223B1 (ko) 2009-09-21
CN100335049C (zh) 2007-09-05
JP2009114217A (ja) 2009-05-28
HUP0302422A2 (hu) 2003-10-28
RU2694361C3 (ru) 2020-07-20
AR030609A1 (es) 2003-08-27
US20140235665A1 (en) 2014-08-21
ZA200301673B (en) 2003-11-26
NL300757I1 (cs) 2015-12-29
US8114890B1 (en) 2012-02-14
CZ304740B6 (cs) 2014-09-17
HU229319B1 (en) 2013-10-28
AR100291A2 (es) 2016-09-28
BR0114042A (pt) 2003-07-22
JP2004508327A (ja) 2004-03-18
US8748454B2 (en) 2014-06-10
DK1857105T3 (da) 2010-09-20
DE60131547T2 (de) 2008-10-23
KR20030029919A (ko) 2003-04-16
US8071613B2 (en) 2011-12-06
RU2694361C2 (ru) 2019-07-12
IL154534A0 (en) 2003-09-17
BRPI0114042B1 (pt) 2016-11-08
NO20030996L (no) 2003-05-02
US20030040528A1 (en) 2003-02-27
EP1857105A2 (en) 2007-11-21
JP4684334B2 (ja) 2011-05-18
RU2694361C9 (ru) 2019-12-25
ATE476975T1 (de) 2010-08-15
TWI305147B (en) 2009-01-11
ES2347697T3 (es) 2010-11-03
US20030216465A1 (en) 2003-11-20
US6414016B1 (en) 2002-07-02
US20120022152A1 (en) 2012-01-26
DE60131547D1 (de) 2008-01-03
KR100901102B1 (ko) 2009-06-08
CA2419741C (en) 2010-11-30
KR20080091278A (ko) 2008-10-09
EP1315485A1 (en) 2003-06-04
NL300757I2 (cs) 2015-12-29
EP1315485B1 (en) 2007-11-21
EP1857105A3 (en) 2008-03-05
HUP0302422A3 (en) 2005-02-28
EP1857105B1 (en) 2010-08-11
BRPI0114042B8 (pt) 2021-05-25

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