ATE476975T1 - Abführende zusammensetzungen - Google Patents

Abführende zusammensetzungen

Info

Publication number
ATE476975T1
ATE476975T1 AT07016834T AT07016834T ATE476975T1 AT E476975 T1 ATE476975 T1 AT E476975T1 AT 07016834 T AT07016834 T AT 07016834T AT 07016834 T AT07016834 T AT 07016834T AT E476975 T1 ATE476975 T1 AT E476975T1
Authority
AT
Austria
Prior art keywords
laxative compositions
laxative
compositions
Prior art date
Application number
AT07016834T
Other languages
English (en)
Inventor
Ryuji Ueno
Original Assignee
Sucampo Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24630250&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE476975(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sucampo Ag filed Critical Sucampo Ag
Application granted granted Critical
Publication of ATE476975T1 publication Critical patent/ATE476975T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/559—Eicosanoids, e.g. leukotrienes or prostaglandins having heterocyclic rings containing hetero atoms other than oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
AT07016834T 2000-09-05 2001-09-04 Abführende zusammensetzungen ATE476975T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/655,760 US6414016B1 (en) 2000-09-05 2000-09-05 Anti-constipation composition

Publications (1)

Publication Number Publication Date
ATE476975T1 true ATE476975T1 (de) 2010-08-15

Family

ID=24630250

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07016834T ATE476975T1 (de) 2000-09-05 2001-09-04 Abführende zusammensetzungen

Country Status (25)

Country Link
US (7) US6414016B1 (de)
EP (2) EP1857105B1 (de)
JP (3) JP2004508327A (de)
KR (2) KR100901102B1 (de)
CN (1) CN100335049C (de)
AR (2) AR030609A1 (de)
AT (1) ATE476975T1 (de)
AU (2) AU2001282615B2 (de)
BR (1) BRPI0114042B8 (de)
CA (1) CA2419741C (de)
CZ (1) CZ304740B6 (de)
DE (2) DE60131547T2 (de)
DK (2) DK1857105T3 (de)
ES (2) ES2347697T3 (de)
HU (1) HU229319B1 (de)
IL (2) IL154534A0 (de)
MX (1) MXPA03001959A (de)
NL (1) NL300757I2 (de)
NO (1) NO332701B1 (de)
NZ (1) NZ524401A (de)
PT (2) PT1857105E (de)
RU (1) RU2694361C3 (de)
TW (1) TWI305147B (de)
WO (1) WO2002020007A1 (de)
ZA (1) ZA200301673B (de)

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ES2221859T3 (es) 1999-10-15 2005-01-16 Sucampo Ag Composicion de compuestos biciclicos y procedimiento para su estabilizacion.
US6414016B1 (en) * 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition
TWI302100B (en) * 2001-05-02 2008-10-21 Sucampo Ag Composition for treating drug-induced constipation
TWI331920B (en) 2001-11-14 2010-10-21 Sucampo Ag Unit dosage form for relieving or treating constipation in human patients
TWI263505B (en) * 2001-11-19 2006-10-11 Sucampo Ag Pharmaceutical composition comprising a C1C-2 channel opener
EP1562604B1 (de) * 2002-10-23 2012-01-04 Sucampo AG Prostaglandinsubstanzen für die behandlung von fettsucht
EP2281564A3 (de) * 2002-12-27 2012-09-05 Sucampo AG Prostaglandinderivate zur Behandlung von abdominalen Schmerzen
JP5294559B2 (ja) * 2003-07-03 2013-09-18 スキャンポ・アーゲー クロライドチャンネルオープナーとしてプロスタグランジンアナログを含む腸溶性組成物
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
TWI387454B (zh) * 2004-09-02 2013-03-01 Sucampo Ag 治療胃腸道疾病之方法及組成物
AR055846A1 (es) 2005-01-27 2007-09-12 Sucampo Ag Compuesto de prostaglandina y metodo para tratar trastornos del sistema nervioso central
EP2308495A1 (de) 2005-03-04 2011-04-13 Sucampo AG Verfahren und Zusammensetzung zur Behandlung von peripheren Gefässkrankheiten
US8524731B2 (en) 2005-03-07 2013-09-03 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
US8518962B2 (en) 2005-03-07 2013-08-27 The University Of Chicago Use of opioid antagonists
US9662325B2 (en) 2005-03-07 2017-05-30 The University Of Chicago Use of opioid antagonists to attenuate endothelial cell proliferation and migration
MX2007010833A (es) * 2005-03-07 2009-02-17 Univ Chicago Uso de antagonistas opioides para atenuar proliferacion y migracion de células endoteliales.
US20060281818A1 (en) 2005-03-21 2006-12-14 Sucampo Ag, North Carolina State University Method for treating mucosal disorders
CN101198334B (zh) * 2005-04-12 2013-02-06 苏坎波公司 前列腺素化合物和质子泵抑制剂用于治疗肠胃病的联合应用
CN101466407B (zh) 2006-01-24 2013-05-15 株式会社·R-技术上野 包含双环化合物的药物组合物和使所述双环化合物稳定的方法
CN103804338A (zh) * 2006-02-07 2014-05-21 株式会社·R-技术上野 用于制备前列腺素衍生物的方法
US20090030072A1 (en) * 2007-07-03 2009-01-29 Sucampo Ag Pharmaceutical combination of opioid and prostaglandin compound
US20090012165A1 (en) 2007-07-03 2009-01-08 Sucampo Ag Pharmaceutical combination of nsaid and prostaglandin compound
US20090082442A1 (en) * 2007-09-26 2009-03-26 Protia, Llc Deuterium-enriched lubiprostone
CN101318948B (zh) 2008-04-01 2011-04-27 上海天伟生物制药有限公司 鲁比前列酮晶体、其制备方法及用途
US8513441B2 (en) * 2008-08-29 2013-08-20 Alphora Research Inc. Prostaglandin synthesis and intermediates for use therein
CN102245176B (zh) * 2008-10-31 2015-05-27 脂质医药有限公司 用作药物的脂肪酸
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
MX345283B (es) 2008-12-31 2017-01-24 Ardelyx Inc Compuestos y metodos para inhibir el antiporte mediado por intercambiador de iones de sodio/iones de hidrogeno (nhe) en el tratamiento de trastornos asociados con retencion de fluido o sobrecarga de sal y trastornos del tracto gastrointestinal.
EP2429982A4 (de) 2009-01-22 2012-09-12 Apotex Pharmachem Inc Verfahren zur herstellung von lubiproston und zwischenprodukte daraus
US9084815B2 (en) * 2009-09-16 2015-07-21 Sucampo Ag Method for treating damage induced by an anti-tumor agent, treating mucositis and treating tumor
CN104958298A (zh) * 2009-09-18 2015-10-07 阿得罗公司 阿片样受体拮抗剂用于胃肠道疾病的用途
CA2779736A1 (en) * 2009-11-03 2011-05-12 Bernard Charles Sherman Stable pharmaceutical formulations comprising lubiprostone
WO2011072383A1 (en) * 2009-12-18 2011-06-23 Apotex Pharmachem Inc. Processes for the purification of lubiprostone
CA2788334A1 (en) 2010-01-28 2011-08-04 Apotex Pharmachem Inc. Polymorphic forms of lubiprostone
US10376481B2 (en) 2012-08-21 2019-08-13 Ardelyx, Inc. Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
CA2880338A1 (en) 2012-08-21 2014-02-27 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
WO2014159679A1 (en) 2013-03-12 2014-10-02 The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Methods for using lubiprostone to absorb fluid from the subretinal space
KR20230132619A (ko) 2013-04-12 2023-09-15 알데릭스, 인코포레이티드 Nhe3-결합 화합물 및 포스페이트 수송을 저해하는 방법
EP3277274A4 (de) 2015-04-01 2018-12-05 Cedars-Sinai Medical Center Antimethanogene lovastatin-analoga oder -derivate und verwendungen davon
WO2016203317A1 (en) * 2015-06-19 2016-12-22 Sucampo Ag Pharmaceutical compositions comprising fatty acid derivative
US11534404B2 (en) 2016-10-06 2022-12-27 Sucampo Ag Multilayer beads for pharmaceutical use
JP7292207B2 (ja) 2017-01-09 2023-06-16 アルデリックス， インコーポレイテッド 消化管障害を処置するために有用な化合物
CA3049679A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Inhibitors of nhe-mediated antiport
US10866140B2 (en) * 2017-04-20 2020-12-15 Shimadzu Corporation Spectrophotometer
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US6414016B1 (en) * 2000-09-05 2002-07-02 Sucampo, A.G. Anti-constipation composition

Also Published As

Publication number Publication date
PT1315485E (pt) 2008-01-23
BRPI0114042B8 (pt) 2021-05-25
EP1315485A1 (de) 2003-06-04
PT1857105E (pt) 2010-10-08
US20140235665A1 (en) 2014-08-21
EP1857105A3 (de) 2008-03-05
DE60142810D1 (de) 2010-09-23
ES2296786T3 (es) 2008-05-01
CA2419741A1 (en) 2002-03-14
US20050222195A1 (en) 2005-10-06
US6610732B2 (en) 2003-08-26
MXPA03001959A (es) 2003-06-24
US6414016B1 (en) 2002-07-02
AR100291A2 (es) 2016-09-28
JP2009114217A (ja) 2009-05-28
ES2347697T3 (es) 2010-11-03
NO20030996L (no) 2003-05-02
DK1857105T3 (da) 2010-09-20
TWI305147B (en) 2009-01-11
CA2419741C (en) 2010-11-30
RU2694361C9 (ru) 2019-12-25
BR0114042A (pt) 2003-07-22
KR20080091278A (ko) 2008-10-09
NL300757I1 (de) 2015-12-29
HUP0302422A2 (hu) 2003-10-28
NL300757I2 (de) 2015-12-29
RU2694361C2 (ru) 2019-07-12
HUP0302422A3 (en) 2005-02-28
CN100335049C (zh) 2007-09-05
IL154534A (en) 2010-04-29
US20030040528A1 (en) 2003-02-27
US20120022152A1 (en) 2012-01-26
CN1655776A (zh) 2005-08-17
KR100918223B1 (ko) 2009-09-21
JP2009286806A (ja) 2009-12-10
US8071613B2 (en) 2011-12-06
KR100901102B1 (ko) 2009-06-08
ZA200301673B (en) 2003-11-26
DE60131547T2 (de) 2008-10-23
JP4684334B2 (ja) 2011-05-18
CZ304740B6 (cs) 2014-09-17
US8748454B2 (en) 2014-06-10
KR20030029919A (ko) 2003-04-16
BRPI0114042B1 (pt) 2016-11-08
NO332701B1 (no) 2012-12-10
EP1857105B1 (de) 2010-08-11
US20120237598A1 (en) 2012-09-20
JP2004508327A (ja) 2004-03-18
EP1857105A2 (de) 2007-11-21
NO20030996D0 (no) 2003-03-04
WO2002020007A1 (en) 2002-03-14
US20030216465A1 (en) 2003-11-20
AU8261501A (en) 2002-03-22
EP1315485B1 (de) 2007-11-21
RU2694361C3 (ru) 2020-07-20
AR030609A1 (es) 2003-08-27
NZ524401A (en) 2004-08-27
DK1315485T3 (da) 2008-03-03
AU2001282615B2 (en) 2006-06-22
HU229319B1 (en) 2013-10-28
US8114890B1 (en) 2012-02-14
DE60131547D1 (de) 2008-01-03
IL154534A0 (en) 2003-09-17

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