NO332191B1 - Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi - Google Patents

Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi Download PDF

Info

Publication number
NO332191B1
NO332191B1 NO20040822A NO20040822A NO332191B1 NO 332191 B1 NO332191 B1 NO 332191B1 NO 20040822 A NO20040822 A NO 20040822A NO 20040822 A NO20040822 A NO 20040822A NO 332191 B1 NO332191 B1 NO 332191B1
Authority
NO
Norway
Prior art keywords
photosensitizing agent
pharmaceutically acceptable
acceptable salt
cells
photosensitizing
Prior art date
Application number
NO20040822A
Other languages
English (en)
Norwegian (no)
Other versions
NO20040822L (no
Inventor
Kristian Berg
N N
Diem Tran
Pal Kristian Selbo
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Publication of NO20040822L publication Critical patent/NO20040822L/no
Publication of NO332191B1 publication Critical patent/NO332191B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/12Keratolytics, e.g. wart or anti-corn preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10Antimycotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Urology & Nephrology (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Detergent Compositions (AREA)
NO20040822A 2001-08-30 2004-02-25 Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi NO332191B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0121023.6A GB0121023D0 (en) 2001-08-30 2001-08-30 Compound
PCT/GB2002/003973 WO2003020309A2 (en) 2001-08-30 2002-08-30 Compound

Publications (2)

Publication Number Publication Date
NO20040822L NO20040822L (no) 2004-04-29
NO332191B1 true NO332191B1 (no) 2012-07-23

Family

ID=9921225

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20040822A NO332191B1 (no) 2001-08-30 2004-02-25 Fotosensibiliserende midler omfattende sulfonerte mesotetrafenylchloriner, farmasoytiske preparater inneholdende slike midler, samt deres anvendelse ved fotokjemisk internalisering av molekyler og i fotodynamisk terapi

Country Status (20)

Country Link
US (2) US7662807B2 (hu)
EP (1) EP1420824B1 (hu)
JP (1) JP5068920B2 (hu)
KR (1) KR100883927B1 (hu)
CN (1) CN100438909C (hu)
AT (1) ATE327768T1 (hu)
BR (1) BRPI0212172B8 (hu)
CA (1) CA2457856C (hu)
DE (1) DE60211918T2 (hu)
ES (1) ES2265047T3 (hu)
GB (1) GB0121023D0 (hu)
HK (1) HK1060974A1 (hu)
HU (1) HU229623B1 (hu)
MX (1) MXPA04001813A (hu)
NO (1) NO332191B1 (hu)
NZ (1) NZ531598A (hu)
PL (1) PL206900B1 (hu)
PT (1) PT1420824E (hu)
RU (1) RU2323940C2 (hu)
WO (1) WO2003020309A2 (hu)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0415263D0 (en) * 2004-07-07 2004-08-11 Norwegian Radium Hospital Res Method
FR2877943B1 (fr) 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
CN100361994C (zh) * 2004-12-10 2008-01-16 吉林大学 四苯基卟啉衍生物及其在有机电致发光器件中的应用
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
CN101153085B (zh) * 2006-09-25 2010-05-12 中国科学院化学研究所 具有可逆手性的超分子手性膜及其制备方法
EP2123664A1 (en) * 2007-02-19 2009-11-25 Rei Medical Co., Ltd. Novel sugar-linked chlorin derivative and process for production thereof
GB0811955D0 (en) 2008-06-30 2008-07-30 Pci Biotech As Method
KR100972504B1 (ko) * 2008-07-14 2010-07-26 김현종 휴대가 가능한 접철식 노트북 받침대
EP2350058B1 (en) * 2008-09-18 2018-10-24 biolitec Unternehmensbeteiligungs II AG Novel method and application of unsymmetrically meso-substituted porphyrins and chlorins for pdt
GB0819594D0 (en) * 2008-10-24 2008-12-03 Univ Coimbrra Process
GB0914286D0 (en) 2009-08-14 2009-09-30 Pci Biotech As Method
GB0914287D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Compositions
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
CN102653541B (zh) * 2011-03-04 2014-01-15 国家纳米科学中心 一种卟啉化合物及其制备方法和应用
CN102786526B (zh) * 2011-05-20 2014-07-16 国家纳米科学中心 一种卟啉-酞菁二连体及其制备方法和应用
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
CN102952143B (zh) * 2012-11-08 2015-12-02 唐江涛 一种四苯基卟吩的制备方法
US20160040128A1 (en) * 2013-03-15 2016-02-11 Pci Biotech As Method
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
CA2922320C (en) 2013-08-28 2022-11-22 Pci Biotech As Enhanced photochemical internalisation using a tlr ligand
NZ729408A (en) 2014-08-28 2021-12-24 Pci Biotech As A method of photochemical internalization (pci) utilizing a antigenic molecule, a photosensitizing agent, and a cytokine
CN104459099B (zh) * 2014-12-18 2016-04-13 东南大学 卟啉衍生物在制备检测炎症相关疾病试剂中的应用
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
KR20190068573A (ko) 2016-10-14 2019-06-18 피씨아이 바이오테크 에이에스 젬시타빈의 tpcs-2a 유도된 광화학 내재화로의 담관암의 치료
GB201718631D0 (en) 2017-11-10 2017-12-27 Pci Biotech As Method
EP3823668A1 (en) 2018-07-16 2021-05-26 DCPrime B.V. A combination product for use in tumor vaccination
JP2022530044A (ja) 2019-04-25 2022-06-27 ディーシープライム・ベスローテン・フェンノートシャップ 腫瘍ワクチン接種方法
CN112898310A (zh) * 2019-12-03 2021-06-04 中国石油天然气股份有限公司 地质卟啉加氢衍生化方法、所得加氢产物及同位素分析法
WO2021191871A1 (en) 2020-03-27 2021-09-30 Dcprime B.V. In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
EP4127139A1 (en) 2020-03-27 2023-02-08 Mendus B.V. Ex vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
AU2021375493A1 (en) 2020-11-05 2023-06-29 Mendus B.V. Use of tumor-independent antigens in immunotherapies
JP2024510989A (ja) 2021-03-12 2024-03-12 メンドゥス・ベスローテン・フェンノートシャップ ワクチン接種方法及びcd47遮断薬の使用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204856B (en) 1987-08-12 1992-02-28 Orszagos Mueszaki Fejlesztesi Process for releasing cell mixtures and tissues from undesired populations and for producing monoclonal antibody - hematoporphyrin conjugates
JPH05253466A (ja) * 1992-03-12 1993-10-05 Res Dev Corp Of Japan 磁気異方性薄膜の製造方法
NO180167C (no) 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
JP2000007693A (ja) 1998-06-26 2000-01-11 Lederle Japan Ltd クロリン誘導体
GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
AU4139600A (en) * 1999-04-14 2000-11-14 University Of British Columbia, The 1,3-dipolar cycloadditions to polypyrrolic macrocycles

Also Published As

Publication number Publication date
AU2002313562B2 (en) 2006-09-07
RU2323940C2 (ru) 2008-05-10
CA2457856A1 (en) 2003-03-13
DE60211918T2 (de) 2007-01-18
BRPI0212172B8 (pt) 2021-05-25
JP5068920B2 (ja) 2012-11-07
JP2005507383A (ja) 2005-03-17
DE60211918D1 (en) 2006-07-06
CA2457856C (en) 2011-01-25
RU2004109228A (ru) 2005-04-10
WO2003020309A3 (en) 2003-10-30
BRPI0212172A8 (pt) 2018-12-18
BRPI0212172B1 (pt) 2019-03-06
GB0121023D0 (en) 2001-10-24
NZ531598A (en) 2005-09-30
US8096419B2 (en) 2012-01-17
CN1549729A (zh) 2004-11-24
US7662807B2 (en) 2010-02-16
BR0212172A (pt) 2004-07-20
PL369289A1 (en) 2005-04-18
ATE327768T1 (de) 2006-06-15
US20060052433A1 (en) 2006-03-09
CN100438909C (zh) 2008-12-03
PT1420824E (pt) 2006-08-31
KR20040032983A (ko) 2004-04-17
NO20040822L (no) 2004-04-29
PL206900B1 (pl) 2010-10-29
HUP0401434A3 (en) 2008-05-28
HK1060974A1 (en) 2004-09-03
EP1420824A2 (en) 2004-05-26
EP1420824B1 (en) 2006-05-31
MXPA04001813A (es) 2005-03-07
ES2265047T3 (es) 2007-02-01
KR100883927B1 (ko) 2009-02-18
HU229623B1 (en) 2014-03-28
US20100121255A1 (en) 2010-05-13
HUP0401434A2 (hu) 2004-12-28
WO2003020309A2 (en) 2003-03-13

Similar Documents

Publication Publication Date Title
EP1420824B1 (en) Sulfonated chlorines as photosensitizer
EP2464384B1 (en) Salt of a photosensitizing agent for use in photochemical internalization
Ghosh et al. Self-assembled porphyrin–peptide cages for photodynamic therapy
Lim et al. Photodynamic characterization of amino acid conjugated 151-hydroxypurpurin-7-lactone for cancer treatment
AU2002313562C1 (en) Compound
Wang et al. Synthesis and evolution of S-Porphin sodium as a potential antitumor agent for photodynamic therapy against breast cancer
US20210052628A1 (en) Method
AU2002313562A1 (en) Compound
GB2420784A (en) Phototherapeutic amphiphilic phthalocyanine-based compounds where 1 peripheral ring system is more hydrophilic & has more hydrophilic groups than the other 3
CN108136018A (zh) 缀合物
Liang et al. Preparation and pharmacological evaluation of A3B-type tetraphenyltetrabenzoporphyrins for photodynamic anti-tumor therapy
Faiza et al. PHOTODYNAMIC EFFECT OF NEW PORPHYRIN DERIVATIVE FOR CANCER TREATMENT
Feng Preparation and Evaluation of Pyropheophorbide a Derivatives
Soldani et al. Apoptosis as a consequence of multiple organelle damage in cultured tumor cells after photosensitization with rose Bengal acetate
KR20050027197A (ko) 신규한 포르피린 화합물

Legal Events

Date Code Title Description
MK1K Patent expired