ATE327768T1 - Sulfonierte chlorine als photosensitizer - Google Patents

Sulfonierte chlorine als photosensitizer

Info

Publication number
ATE327768T1
ATE327768T1 AT02753157T AT02753157T ATE327768T1 AT E327768 T1 ATE327768 T1 AT E327768T1 AT 02753157 T AT02753157 T AT 02753157T AT 02753157 T AT02753157 T AT 02753157T AT E327768 T1 ATE327768 T1 AT E327768T1
Authority
AT
Austria
Prior art keywords
meso
tetraphenylporphyrin
photosensitizers
sulfonated
chlorine
Prior art date
Application number
AT02753157T
Other languages
English (en)
Inventor
Kristian Berg
Diem Tran
P L Kristian Selbo
Claude Di Rimington
Original Assignee
Pci Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pci Biotech As filed Critical Pci Biotech As
Application granted granted Critical
Publication of ATE327768T1 publication Critical patent/ATE327768T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/008—Two-Photon or Multi-Photon PDT, e.g. with upconverting dyes or photosensitisers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Pain & Pain Management (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Detergent Compositions (AREA)
  • Photoreceptors In Electrophotography (AREA)
AT02753157T 2001-08-30 2002-08-30 Sulfonierte chlorine als photosensitizer ATE327768T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0121023.6A GB0121023D0 (en) 2001-08-30 2001-08-30 Compound

Publications (1)

Publication Number Publication Date
ATE327768T1 true ATE327768T1 (de) 2006-06-15

Family

ID=9921225

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02753157T ATE327768T1 (de) 2001-08-30 2002-08-30 Sulfonierte chlorine als photosensitizer

Country Status (20)

Country Link
US (2) US7662807B2 (de)
EP (1) EP1420824B1 (de)
JP (1) JP5068920B2 (de)
KR (1) KR100883927B1 (de)
CN (1) CN100438909C (de)
AT (1) ATE327768T1 (de)
BR (1) BRPI0212172B8 (de)
CA (1) CA2457856C (de)
DE (1) DE60211918T2 (de)
ES (1) ES2265047T3 (de)
GB (1) GB0121023D0 (de)
HK (1) HK1060974A1 (de)
HU (1) HU229623B1 (de)
MX (1) MXPA04001813A (de)
NO (1) NO332191B1 (de)
NZ (1) NZ531598A (de)
PL (1) PL206900B1 (de)
PT (1) PT1420824E (de)
RU (1) RU2323940C2 (de)
WO (1) WO2003020309A2 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0415263D0 (en) * 2004-07-07 2004-08-11 Norwegian Radium Hospital Res Method
FR2877943B1 (fr) * 2004-11-16 2008-09-05 Univ De Coimbra Nouveaux derives de porphyrine, notamment chlorines et/ou bacteriochlorine, et leurs applications en therapie photodynamique
CN100361994C (zh) * 2004-12-10 2008-01-16 吉林大学 四苯基卟啉衍生物及其在有机电致发光器件中的应用
GB0613753D0 (en) 2006-07-11 2006-08-23 Norwegian Radium Hospital Res Method
CN101153085B (zh) * 2006-09-25 2010-05-12 中国科学院化学研究所 具有可逆手性的超分子手性膜及其制备方法
WO2008102669A1 (ja) * 2007-02-19 2008-08-28 Rei Medical Co., Ltd. 新規な糖連結クロリン誘導体及びその製造方法
GB0811955D0 (en) 2008-06-30 2008-07-30 Pci Biotech As Method
KR100972504B1 (ko) * 2008-07-14 2010-07-26 김현종 휴대가 가능한 접철식 노트북 받침대
CN102159569B (zh) * 2008-09-18 2016-02-03 拜莱泰克制药市场有限公司 用于pdt的不对称内消旋取代的卟啉和二氢卟酚及其应用
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
GB0914286D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Method
GB0914287D0 (en) * 2009-08-14 2009-09-30 Pci Biotech As Compositions
CN102260269B (zh) * 2010-05-25 2013-11-06 苏州和健医药科技有限公司 一种含有卟啉或二氢卟吩的树状化合物及其应用
CN102653541B (zh) * 2011-03-04 2014-01-15 国家纳米科学中心 一种卟啉化合物及其制备方法和应用
CN102786526B (zh) * 2011-05-20 2014-07-16 国家纳米科学中心 一种卟啉-酞菁二连体及其制备方法和应用
US8907081B2 (en) 2011-05-27 2014-12-09 Sharp Laboratories Of America, Inc. Long wavelength absorbing porphyrin photosensitizers for dye-sensitized solar cells
GB201208548D0 (en) 2012-05-15 2012-06-27 Pci Biotech As Compound and method
CN102952143B (zh) * 2012-11-08 2015-12-02 唐江涛 一种四苯基卟吩的制备方法
CA2906279A1 (en) * 2013-03-15 2014-09-18 Pci Biotech As A method of generating antigen presenting cells using photochemical internalisation
EP3038619B1 (de) 2013-08-28 2023-10-04 PCI Biotech AS Verbindung und verfahren für impfung und immunisierung
WO2015028575A1 (en) * 2013-08-28 2015-03-05 Pci Biotech As Immunisation method by photochemical internalisation
AU2015308345B9 (en) 2014-08-28 2020-12-24 Pci Biotech As Compound and method
CN104459099B (zh) * 2014-12-18 2016-04-13 东南大学 卟啉衍生物在制备检测炎症相关疾病试剂中的应用
GB201503776D0 (en) 2015-03-05 2015-04-22 Pci Biotech As Compound and method
RU2019109682A (ru) 2016-10-14 2020-11-16 ПиСиАй БИОТЕК АС Лечение холангиокарциномы с применением tpcs-2-индуцированной фотохимической интернализации гемцитабина
GB201718631D0 (en) 2017-11-10 2017-12-27 Pci Biotech As Method
EP3823668A1 (de) 2018-07-16 2021-05-26 DCPrime B.V. Kombinationsprodukt zur verwendung in der tumorimpfung
WO2020217226A1 (en) 2019-04-25 2020-10-29 Dcprime B.V. Methods of tumor vaccination
CN112898310A (zh) * 2019-12-03 2021-06-04 中国石油天然气股份有限公司 地质卟啉加氢衍生化方法、所得加氢产物及同位素分析法
CN115916963A (zh) 2020-03-27 2023-04-04 门德斯有限公司 白血病来源的经修饰细胞用于增强过继性细胞治疗的效力的离体用途
EP4125943A1 (de) 2020-03-27 2023-02-08 Mendus B.V. In-vivo-verwendung von modifizierten zellen leukämischen ursprungs zur verbesserung der wirksamkeit einer adoptiven zelltherapie
JP2023547520A (ja) 2020-11-05 2023-11-10 メンドゥス・ベスローテン・フェンノートシャップ 免疫療法における腫瘍非依存性抗原の使用
AU2022235341A1 (en) 2021-03-12 2023-09-21 Mendus B.V. Methods of vaccination and use of cd47 blockade

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU204856B (en) 1987-08-12 1992-02-28 Orszagos Mueszaki Fejlesztesi Process for releasing cell mixtures and tissues from undesired populations and for producing monoclonal antibody - hematoporphyrin conjugates
JPH05253466A (ja) * 1992-03-12 1993-10-05 Res Dev Corp Of Japan 磁気異方性薄膜の製造方法
NO180167C (no) 1994-09-08 1997-02-26 Photocure As Fotokjemisk fremgangsmåte til å innföre molekyler i cellers cytosol
GB9700396D0 (en) 1997-01-10 1997-02-26 Photocure As Photochemotherapeutic compositions
JP2000007693A (ja) * 1998-06-26 2000-01-11 Lederle Japan Ltd クロリン誘導体
GB9905911D0 (en) 1999-03-15 1999-05-05 Photocure As Method
AU4139600A (en) * 1999-04-14 2000-11-14 University Of British Columbia, The 1,3-dipolar cycloadditions to polypyrrolic macrocycles

Also Published As

Publication number Publication date
CN100438909C (zh) 2008-12-03
RU2004109228A (ru) 2005-04-10
WO2003020309A3 (en) 2003-10-30
DE60211918D1 (en) 2006-07-06
NZ531598A (en) 2005-09-30
JP5068920B2 (ja) 2012-11-07
KR100883927B1 (ko) 2009-02-18
MXPA04001813A (es) 2005-03-07
BRPI0212172A8 (pt) 2018-12-18
HK1060974A1 (en) 2004-09-03
JP2005507383A (ja) 2005-03-17
RU2323940C2 (ru) 2008-05-10
NO332191B1 (no) 2012-07-23
HUP0401434A2 (hu) 2004-12-28
BRPI0212172B1 (pt) 2019-03-06
CA2457856C (en) 2011-01-25
CN1549729A (zh) 2004-11-24
US8096419B2 (en) 2012-01-17
BR0212172A (pt) 2004-07-20
WO2003020309A2 (en) 2003-03-13
EP1420824A2 (de) 2004-05-26
KR20040032983A (ko) 2004-04-17
US7662807B2 (en) 2010-02-16
US20060052433A1 (en) 2006-03-09
NO20040822L (no) 2004-04-29
AU2002313562B2 (en) 2006-09-07
PT1420824E (pt) 2006-08-31
GB0121023D0 (en) 2001-10-24
CA2457856A1 (en) 2003-03-13
HUP0401434A3 (en) 2008-05-28
BRPI0212172B8 (pt) 2021-05-25
ES2265047T3 (es) 2007-02-01
DE60211918T2 (de) 2007-01-18
EP1420824B1 (de) 2006-05-31
US20100121255A1 (en) 2010-05-13
HU229623B1 (en) 2014-03-28
PL206900B1 (pl) 2010-10-29
PL369289A1 (en) 2005-04-18

Similar Documents

Publication Publication Date Title
ATE327768T1 (de) Sulfonierte chlorine als photosensitizer
Awuah et al. Boron dipyrromethene (BODIPY)-based photosensitizers for photodynamic therapy
Josefsen et al. Photodynamic therapy and the development of metal‐based photosensitisers
DK0462206T3 (da) Ekspanderede porphyriner: Store porphyrin-lignende tripyrroldimethinafledte makrocykler
DK1558616T3 (da) Meso-substituerede porphyriner
RU2399622C2 (ru) Новые производные порфиринов, в частности хлорины и/или бактериохлорины, и их применение в фотодинамической терапии
CA2127530A1 (en) Metal complexes of water soluble texaphyrins
EA200200616A1 (ru) Химические производные и их применение в качестве антителомеразного агента
DK1381611T3 (da) Metalsubstituerede ikke-centrosymmetriske phthalocyaninanaloger, fremstilling heraf og anvendelse i fotodynamisk terapi samt in vivo diagnostik
JPH04501717A (ja) 光活性化合物から誘導される前活性化治療剤
EP1404678A4 (de) Wasserlösliche porphyrinderivate für die photodynamische therapie, deren verwendung und herstellung
GT200100232A (es) Derivados de pirimidina.
Dairou et al. Self‐association of Disulfonated Deuteroporphyrin and its Esters in Aqueous Solution and Photosensitized Production of Singlet Oxygen by the Dimers¶
DK1470127T3 (da) N,N'-dimethylerede N-inverterede porphyriner
Nowell et al. EtNBS in photodynamic therapy
Zane et al. Photosensitizers—systemic sensitization
Wen The applications of laser spectroscopy in analytical chemistry and biochemistry: investigating the photophysics of hypericin and hypocrellin, as well as the structure of porcine fructose-1, 6-bisphosphatase
Eckhauser et al. Biodistribution of 55 Fe (II) phthalocyanine tetrasulphonate (55 Fe (II)-TsPc)

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1420824

Country of ref document: EP