NO331734B1 - Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. - Google Patents
Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. Download PDFInfo
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- NO331734B1 NO331734B1 NO20011308A NO20011308A NO331734B1 NO 331734 B1 NO331734 B1 NO 331734B1 NO 20011308 A NO20011308 A NO 20011308A NO 20011308 A NO20011308 A NO 20011308A NO 331734 B1 NO331734 B1 NO 331734B1
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- Prior art keywords
- acid
- acceptable salts
- physiologically acceptable
- nme
- cyclo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Physical Education & Sports Medicine (AREA)
- Oncology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Dermatology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19842415A DE19842415A1 (de) | 1998-09-16 | 1998-09-16 | Pharmazeutische Zubereitung |
| PCT/EP1999/006654 WO2000015244A2 (de) | 1998-09-16 | 1999-09-09 | Pharmazeutische zubereitung enthaltend ein cyclo-peptide und ein chemotherapeutikum oder einen angiogeneseinhibitor |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20011308D0 NO20011308D0 (no) | 2001-03-15 |
| NO20011308L NO20011308L (no) | 2001-03-15 |
| NO331734B1 true NO331734B1 (no) | 2012-03-12 |
Family
ID=7881169
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20011308A NO331734B1 (no) | 1998-09-16 | 2001-03-15 | Anvendelse av et syklopeptid til fremstilling av et medikament for bekjempelse av tumorer ved stralebehandling. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6683051B1 (pt) |
| EP (2) | EP1113809B1 (pt) |
| JP (2) | JP2002524526A (pt) |
| KR (1) | KR100703253B1 (pt) |
| CN (2) | CN1201812C (pt) |
| AR (2) | AR022382A1 (pt) |
| AT (2) | ATE432707T1 (pt) |
| AU (1) | AU765073B2 (pt) |
| BR (1) | BR9913737A (pt) |
| CA (1) | CA2344151A1 (pt) |
| CO (1) | CO5140070A1 (pt) |
| CZ (1) | CZ302908B6 (pt) |
| DE (3) | DE19842415A1 (pt) |
| DK (2) | DK1466615T3 (pt) |
| ES (2) | ES2327331T3 (pt) |
| HU (1) | HUP0103521A3 (pt) |
| ID (1) | ID29226A (pt) |
| IL (2) | IL141516A0 (pt) |
| MY (1) | MY129572A (pt) |
| NO (1) | NO331734B1 (pt) |
| NZ (1) | NZ510040A (pt) |
| PE (1) | PE20001046A1 (pt) |
| PL (1) | PL201902B1 (pt) |
| PT (2) | PT1113809E (pt) |
| RU (1) | RU2227041C2 (pt) |
| SI (1) | SI1113809T1 (pt) |
| SK (1) | SK287012B6 (pt) |
| TR (1) | TR200100765T2 (pt) |
| TW (1) | TW576744B (pt) |
| WO (1) | WO2000015244A2 (pt) |
| ZA (1) | ZA200103073B (pt) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7740841B1 (en) * | 2000-01-28 | 2010-06-22 | Sunnybrook Health Science Center | Therapeutic method for reducing angiogenesis |
| EP1349574A2 (en) * | 2001-01-09 | 2003-10-08 | MERCK PATENT GmbH | Combination therapy using receptor tyrosine kinase inhibitors and angiogenesis inhibitors |
| JP4542783B2 (ja) * | 2002-03-05 | 2010-09-15 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | スルホンアミド含有複素環化合物及び血管新生抑制剤とを組み合わせてなる抗腫瘍剤 |
| US20050226865A1 (en) * | 2004-04-02 | 2005-10-13 | Regents Of The University Of California | Methods and compositions for treating and preventing diseases associated with alphavbeta5 integrin |
| BRPI0618050A2 (pt) * | 2005-11-02 | 2011-08-16 | Univ Duke | uso de peptìdeo egfrviii e vacina antitumor em combinação com outros componentes para o tratamento de tumor |
| US20110165150A1 (en) * | 2006-01-18 | 2011-07-07 | Merck Patent Gmbh | Isolated organ perfusion combination therapy of cancer |
| US20090130098A1 (en) * | 2006-01-18 | 2009-05-21 | Merck Patent Gmbh | Specific therapy using integrin ligands for treating cancer |
| ES2399159T3 (es) | 2007-01-18 | 2013-03-26 | Merck Patent Gmbh | Terapia y medicamento específicos usando ligandos de integrinas para el tratamiento del cáncer |
| WO2009010290A2 (en) | 2007-07-17 | 2009-01-22 | Merck Patent Gmbh | Engineered anti-alpha v- integrin hybrid antibodies |
| WO2010051667A1 (zh) * | 2008-11-10 | 2010-05-14 | 复旦大学 | 一种环肽纳米管药物组合物及其应用 |
| US20110230423A1 (en) * | 2008-11-20 | 2011-09-22 | Martin Andreas Picard | Therapy and medicament using integrin ligands for treating cancer |
| SG176103A1 (en) | 2009-05-25 | 2011-12-29 | Merck Patent Gmbh | Continuous administration of cilengitide in cancer treatments |
| BR112012001463A2 (pt) | 2009-07-24 | 2016-03-15 | Univ California | métodos e composições para tratar e prevenir doença associada à integrina alfavbeta5 |
| EP2509583B1 (en) | 2009-12-10 | 2019-05-15 | Merck Patent GmbH | Pharmaceutical composition comprising oligopeptides, preferably cilengitide |
| CN103153328A (zh) | 2010-07-16 | 2013-06-12 | 默克专利股份有限公司 | 肽在乳腺癌和/或骨转移灶的治疗中的用途 |
| WO2012069149A1 (en) | 2010-11-23 | 2012-05-31 | Merck Patent Gmbh | Solution comprising cyclic oligopeptides |
| PT2672994T (pt) | 2011-02-11 | 2018-10-22 | Merck Patent Gmbh | Anticorpo anti-integrina alfa-v para o tratamento do cancro da próstata |
| WO2012110200A1 (en) | 2011-02-18 | 2012-08-23 | Merck Patent Gmbh | Cyclic peptide cyclo (l -arginyl - glycyl - l -aspartyl - d - phenylalanyl - n-methyl - l -valyl), compositions thereof, and use thereof in methods for treating graft -versus - host disease |
| AU2012266803B2 (en) | 2011-06-09 | 2017-02-02 | Merck Patent Gmbh | Treatment of cancers and metastases with suspensions of cilengitide in carrier |
| WO2013130775A1 (en) * | 2012-03-01 | 2013-09-06 | Dizerega, Gere, S. | Methods for treating patients undergoing multi-cycle chemotherapy |
| CN103333227B (zh) * | 2013-06-07 | 2015-10-07 | 东南大学 | 转移肿瘤缺失蛋白小分子环肽抑制剂及其制备方法与应用 |
| EP3510407A1 (en) | 2016-09-08 | 2019-07-17 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for diagnosing and treating nephrotic syndrome |
| JP2019208422A (ja) * | 2018-06-04 | 2019-12-12 | コリア・インスティテュート・オブ・サイエンス・アンド・テクノロジー | ヒアルロニダーゼを含む新規な組換えエキソソーム及びその用途 |
| GB201911816D0 (en) * | 2019-08-16 | 2019-10-02 | Univ London Queen Mary | Treatment |
| GB202103122D0 (en) * | 2021-03-05 | 2021-04-21 | Univ London Queen Mary | Treatment |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH04367367A (ja) | 1991-06-11 | 1992-12-18 | Nkk Corp | ロータリノズル |
| US5786373A (en) | 1992-10-14 | 1998-07-28 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| WO1994012181A1 (en) | 1992-12-01 | 1994-06-09 | Merck & Co., Inc. | Fibrinogen receptor antagonists |
| CA2190870A1 (en) | 1994-05-27 | 1995-12-07 | George D. Hartman | Compounds for inhibiting osteoclast-mediated bone resorption |
| WO1996000574A1 (en) | 1994-06-29 | 1996-01-11 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
| CA2193966A1 (en) | 1994-06-29 | 1996-01-11 | Fadia El-Fehail Ali | Vitronectin receptor antagonists |
| ATE170179T1 (de) | 1994-11-02 | 1998-09-15 | Merck Patent Gmbh | Adhäsionsrezeptor-antagonisten |
| DE19534177A1 (de) * | 1995-09-15 | 1997-03-20 | Merck Patent Gmbh | Cyclische Adhäsionsinhibitoren |
| DE19548709A1 (de) * | 1995-12-23 | 1997-07-03 | Merck Patent Gmbh | Tyrosinderivate |
| JPH09208571A (ja) * | 1996-02-02 | 1997-08-12 | Takeda Chem Ind Ltd | アルキリデンシクロヘキサン誘導体 |
| WO1997041844A1 (en) * | 1996-05-09 | 1997-11-13 | Alcon Laboratories, Inc. | Combinations of angiostatic compounds |
| US5919815A (en) * | 1996-05-22 | 1999-07-06 | Neuromedica, Inc. | Taxane compounds and compositions |
| HUP9902099A3 (en) * | 1996-05-31 | 2001-10-29 | Scripps Research Inst | Methods and compositions useful for inhibition of angiogenesis |
| JPH1081631A (ja) * | 1996-07-17 | 1998-03-31 | Takeda Chem Ind Ltd | 癌転移または再発抑制剤 |
| DE19629816A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Cycloalkyl-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| DE19629817A1 (de) | 1996-07-24 | 1998-01-29 | Hoechst Ag | Neue Imino-Derivate als Inhibitoren der Knochenresorption und Vitronectinrezeptor-Antagonisten |
| UA60311C2 (uk) * | 1996-10-02 | 2003-10-15 | Смітклайн Бічам Корпорейшн | Антагоністи рецептора вітронектину, спосіб одержання цих сполук та фармацевтична композиція |
| WO1998031359A1 (en) * | 1997-01-17 | 1998-07-23 | Merck & Co., Inc. | Integrin antagonists |
| DE19850131A1 (de) | 1998-10-30 | 2000-05-04 | Merck Patent Gmbh | Chromenon- und Chromanonderivate |
-
1998
- 1998-09-16 DE DE19842415A patent/DE19842415A1/de not_active Withdrawn
-
1999
- 1999-09-09 CZ CZ20010932A patent/CZ302908B6/cs not_active IP Right Cessation
- 1999-09-09 HU HU0103521A patent/HUP0103521A3/hu unknown
- 1999-09-09 BR BR9913737-2A patent/BR9913737A/pt not_active Application Discontinuation
- 1999-09-09 SK SK337-2001A patent/SK287012B6/sk not_active IP Right Cessation
- 1999-09-09 ES ES04006076T patent/ES2327331T3/es not_active Expired - Lifetime
- 1999-09-09 PL PL348026A patent/PL201902B1/pl not_active IP Right Cessation
- 1999-09-09 CN CNB998133876A patent/CN1201812C/zh not_active Expired - Fee Related
- 1999-09-09 TR TR2001/00765T patent/TR200100765T2/xx unknown
- 1999-09-09 JP JP2000569828A patent/JP2002524526A/ja active Pending
- 1999-09-09 DK DK04006076T patent/DK1466615T3/da active
- 1999-09-09 RU RU2001110104/15A patent/RU2227041C2/ru not_active IP Right Cessation
- 1999-09-09 NZ NZ510040A patent/NZ510040A/en not_active IP Right Cessation
- 1999-09-09 PT PT99969031T patent/PT1113809E/pt unknown
- 1999-09-09 CN CNB2004100834955A patent/CN100352494C/zh not_active Expired - Fee Related
- 1999-09-09 SI SI9930792T patent/SI1113809T1/xx unknown
- 1999-09-09 EP EP99969031A patent/EP1113809B1/de not_active Expired - Lifetime
- 1999-09-09 DE DE59911881T patent/DE59911881D1/de not_active Expired - Lifetime
- 1999-09-09 DK DK99969031T patent/DK1113809T3/da active
- 1999-09-09 WO PCT/EP1999/006654 patent/WO2000015244A2/de active IP Right Grant
- 1999-09-09 AT AT04006076T patent/ATE432707T1/de active
- 1999-09-09 ID IDW20010746A patent/ID29226A/id unknown
- 1999-09-09 ES ES99969031T patent/ES2241363T3/es not_active Expired - Lifetime
- 1999-09-09 AT AT99969031T patent/ATE292470T1/de active
- 1999-09-09 KR KR1020017003238A patent/KR100703253B1/ko not_active IP Right Cessation
- 1999-09-09 CA CA002344151A patent/CA2344151A1/en not_active Abandoned
- 1999-09-09 AU AU59758/99A patent/AU765073B2/en not_active Ceased
- 1999-09-09 PT PT04006076T patent/PT1466615E/pt unknown
- 1999-09-09 DE DE59915033T patent/DE59915033D1/de not_active Expired - Lifetime
- 1999-09-09 IL IL14151699A patent/IL141516A0/xx unknown
- 1999-09-09 US US09/787,374 patent/US6683051B1/en not_active Expired - Lifetime
- 1999-09-09 EP EP04006076A patent/EP1466615B1/de not_active Expired - Lifetime
- 1999-09-13 MY MYPI99003955A patent/MY129572A/en unknown
- 1999-09-13 PE PE1999000926A patent/PE20001046A1/es not_active Application Discontinuation
- 1999-09-15 AR ARP990104617A patent/AR022382A1/es not_active Application Discontinuation
- 1999-09-16 TW TW088116003A patent/TW576744B/zh not_active IP Right Cessation
- 1999-09-16 CO CO99058733A patent/CO5140070A1/es unknown
-
2001
- 2001-02-19 IL IL141516A patent/IL141516A/en not_active IP Right Cessation
- 2001-03-15 NO NO20011308A patent/NO331734B1/no not_active IP Right Cessation
- 2001-04-12 ZA ZA200103073A patent/ZA200103073B/en unknown
-
2010
- 2010-09-15 AR ARP100103356A patent/AR078175A2/es not_active Application Discontinuation
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2011
- 2011-08-12 JP JP2011176480A patent/JP2011252012A/ja active Pending
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