NO327149B1 - Fremgangsmate for isolering av et rekombinant humant neutrofin, eller genetisk modifisert form av dette, fra en blanding som inneholder andre proteiner og en variant av dette rekombinante humane neutrofinet som kan inkludere en feilfoldet variant, en feilaktig proteolytisk prosessert variant, eller en glykosyleringsvariant av dette rekombinante humane neutrofinet, fremgangsmate for seperasjon av et neutrofin fra en kjemisk variant av dette neutrofinet. - Google Patents
Fremgangsmate for isolering av et rekombinant humant neutrofin, eller genetisk modifisert form av dette, fra en blanding som inneholder andre proteiner og en variant av dette rekombinante humane neutrofinet som kan inkludere en feilfoldet variant, en feilaktig proteolytisk prosessert variant, eller en glykosyleringsvariant av dette rekombinante humane neutrofinet, fremgangsmate for seperasjon av et neutrofin fra en kjemisk variant av dette neutrofinet. Download PDFInfo
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- NO327149B1 NO327149B1 NO19992353A NO992353A NO327149B1 NO 327149 B1 NO327149 B1 NO 327149B1 NO 19992353 A NO19992353 A NO 19992353A NO 992353 A NO992353 A NO 992353A NO 327149 B1 NO327149 B1 NO 327149B1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/48—Nerve growth factor [NGF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Epoxy Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3083896P | 1996-11-15 | 1996-11-15 | |
US4785597P | 1997-05-29 | 1997-05-29 | |
PCT/US1997/021068 WO1998021234A2 (en) | 1996-11-15 | 1997-11-14 | Purification of neurotrophins |
Publications (3)
Publication Number | Publication Date |
---|---|
NO992353D0 NO992353D0 (no) | 1999-05-14 |
NO992353L NO992353L (no) | 1999-07-09 |
NO327149B1 true NO327149B1 (no) | 2009-05-04 |
Family
ID=26706516
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19992353A NO327149B1 (no) | 1996-11-15 | 1999-05-14 | Fremgangsmate for isolering av et rekombinant humant neutrofin, eller genetisk modifisert form av dette, fra en blanding som inneholder andre proteiner og en variant av dette rekombinante humane neutrofinet som kan inkludere en feilfoldet variant, en feilaktig proteolytisk prosessert variant, eller en glykosyleringsvariant av dette rekombinante humane neutrofinet, fremgangsmate for seperasjon av et neutrofin fra en kjemisk variant av dette neutrofinet. |
Country Status (21)
Country | Link |
---|---|
US (5) | US6005081A (cs) |
EP (1) | EP0942930B1 (cs) |
JP (3) | JP4671372B2 (cs) |
KR (1) | KR100554332B1 (cs) |
CN (1) | CN1268639C (cs) |
AT (1) | ATE371670T1 (cs) |
AU (1) | AU729459B2 (cs) |
BR (1) | BR9713055A (cs) |
CA (1) | CA2268747A1 (cs) |
CZ (1) | CZ300296B6 (cs) |
DE (1) | DE69738074T2 (cs) |
EA (1) | EA002349B1 (cs) |
ES (1) | ES2293662T3 (cs) |
HU (1) | HU222666B1 (cs) |
ID (1) | ID26697A (cs) |
IL (2) | IL129851A0 (cs) |
NO (1) | NO327149B1 (cs) |
NZ (1) | NZ335207A (cs) |
PL (1) | PL191400B1 (cs) |
TR (1) | TR199901734T2 (cs) |
WO (1) | WO1998021234A2 (cs) |
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SI1308455T1 (sl) * | 1998-05-06 | 2006-08-31 | Genentech Inc | Sestavek, ki obsega protitelesa anti-HER2 |
ES2266188T3 (es) | 2000-03-27 | 2007-03-01 | Genetics Institute, Llc | Procedimientos de purificacion de proteinas altamente anionicas. |
DK1714982T3 (da) * | 2001-06-05 | 2009-05-04 | Genetics Inst Llc | Fremgangsmåde til rensning af stærkt anioniske proteiner |
EP1456233A4 (en) * | 2001-06-15 | 2006-06-21 | Queensland Bioproc Technology | ORMEAU HEMOCYANINE AND METHOD FOR PURIFICATION THEREOF |
WO2004002417A2 (en) | 2002-06-28 | 2004-01-08 | Centocor, Inc. | Mammalian ch1 deleted mimetibodies, compositions, methods and uses |
US7998705B2 (en) * | 2002-08-06 | 2011-08-16 | FUJIFILM Diosynth Biotechnologies U.S.A., Inc | Increased dynamic binding capacity in ion exchange chromatography by addition of polyethylene glycol |
AU2003902066A0 (en) * | 2003-05-01 | 2003-05-15 | Norika Holdings | Extraction process for a pharmaceutical product |
CA2487673C (en) * | 2003-12-02 | 2010-11-02 | F. Hoffmann-La Roche Ag | Improved method for the recombinant production and purification of protein kinases |
EP1538201A1 (en) * | 2003-12-02 | 2005-06-08 | F.Hoffmann-La Roche Ag | Method for the recombinant production and purification of protein kinases |
US20050209148A1 (en) * | 2004-02-20 | 2005-09-22 | Arnon Rosenthal | Methods of treating obesity or diabetes using NT-4/5 |
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SI1917276T1 (en) | 2005-08-26 | 2018-05-31 | Ares Trading S.A. | PROCEDURE FOR PREPARATION OF GLYCOSYLATED INTERFERONE BETA |
US8604175B2 (en) | 2005-12-09 | 2013-12-10 | Ares Trading S.A. | Method for purifying FSH or a FSH mutant |
CN100419422C (zh) * | 2005-12-12 | 2008-09-17 | 北京三诺佳邑生物技术有限责任公司 | 测定神经生长因子含量的方法 |
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KR101398713B1 (ko) | 2005-12-20 | 2014-06-12 | 브리스톨-마이어스 스큅 컴퍼니 | 조성물 및 조성물의 제조 방법 |
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JP2009525319A (ja) * | 2006-02-02 | 2009-07-09 | ライナット ニューロサイエンス コーポレイション | trkBアンタゴニストを投与することにより肥満を治療する方法 |
US9790538B2 (en) * | 2013-03-07 | 2017-10-17 | Apdn (B.V.I.) Inc. | Alkaline activation for immobilization of DNA taggants |
US10741034B2 (en) | 2006-05-19 | 2020-08-11 | Apdn (B.V.I.) Inc. | Security system and method of marking an inventory item and/or person in the vicinity |
BRPI0720473A2 (pt) * | 2006-12-20 | 2014-01-14 | Rinat Neuroscience Corp | Agonistas de trkb para tratamento de distúbios autoimunes |
KR20190140090A (ko) | 2007-07-09 | 2019-12-18 | 제넨테크, 인크. | 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지 |
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WO2010075535A1 (en) * | 2008-12-23 | 2010-07-01 | Regents Of The University Of Minnesota | Neurotrophins and uses thereof |
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JP5699429B2 (ja) * | 2009-12-18 | 2015-04-08 | 東ソー株式会社 | Fcレセプターの精製方法 |
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US9266370B2 (en) | 2012-10-10 | 2016-02-23 | Apdn (B.V.I) Inc. | DNA marking of previously undistinguished items for traceability |
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CN103880943A (zh) * | 2014-01-20 | 2014-06-25 | 厦门北大之路生物工程有限公司 | 一种rhNGF成熟肽的制备方法 |
CN106103121B (zh) | 2014-03-18 | 2019-12-06 | 亚普蒂恩(B.V.I.)公司 | 用于安全应用的加密光学标记物 |
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CN104195160A (zh) * | 2014-08-08 | 2014-12-10 | 厦门北大之路生物工程有限公司 | 一种以Pro-BDNF的形式制备人脑源性神经营养因子的方法 |
US10760182B2 (en) | 2014-12-16 | 2020-09-01 | Apdn (B.V.I.) Inc. | Method and device for marking fibrous materials |
CN106279397A (zh) * | 2015-06-09 | 2017-01-04 | 舒泰神(北京)生物制药股份有限公司 | 一种神经生长因子的提取方法 |
CN109070130B (zh) | 2016-04-11 | 2022-03-22 | 亚普蒂恩(B V I)公司 | 用于标记纤维素产品的方法 |
CN106478801A (zh) * | 2016-10-10 | 2017-03-08 | 未名生物医药有限公司 | 一种从哺乳动物细胞培养物中分离重组人神经生长因子的方法 |
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US10920274B2 (en) | 2017-02-21 | 2021-02-16 | Apdn (B.V.I.) Inc. | Nucleic acid coated submicron particles for authentication |
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CN107973848B (zh) * | 2017-12-28 | 2020-10-16 | 未名生物医药有限公司 | 一种从混合物中分离天然序列神经生长因子的方法 |
CN108467429A (zh) * | 2018-03-26 | 2018-08-31 | 江苏中新医药有限公司 | 疏水层析动态清除重组人神经生长因子前体的方法 |
CN108467428A (zh) * | 2018-03-26 | 2018-08-31 | 江苏中新医药有限公司 | 一种清除rhNGF中N端截短及异常变异体的方法 |
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-
1997
- 1997-11-14 NZ NZ335207A patent/NZ335207A/xx not_active IP Right Cessation
- 1997-11-14 TR TR1999/01734T patent/TR199901734T2/xx unknown
- 1997-11-14 US US08/970,865 patent/US6005081A/en not_active Expired - Lifetime
- 1997-11-14 AU AU54448/98A patent/AU729459B2/en not_active Ceased
- 1997-11-14 JP JP52291398A patent/JP4671372B2/ja not_active Expired - Fee Related
- 1997-11-14 CN CNB971996822A patent/CN1268639C/zh not_active Expired - Fee Related
- 1997-11-14 AT AT97948362T patent/ATE371670T1/de active
- 1997-11-14 ID IDW990339D patent/ID26697A/id unknown
- 1997-11-14 DE DE69738074T patent/DE69738074T2/de not_active Expired - Lifetime
- 1997-11-14 BR BR9713055-9A patent/BR9713055A/pt not_active Application Discontinuation
- 1997-11-14 WO PCT/US1997/021068 patent/WO1998021234A2/en active IP Right Grant
- 1997-11-14 ES ES97948362T patent/ES2293662T3/es not_active Expired - Lifetime
- 1997-11-14 IL IL12985197A patent/IL129851A0/xx active IP Right Grant
- 1997-11-14 PL PL333460A patent/PL191400B1/pl not_active IP Right Cessation
- 1997-11-14 HU HU9903947A patent/HU222666B1/hu not_active IP Right Cessation
- 1997-11-14 CZ CZ0166699A patent/CZ300296B6/cs not_active IP Right Cessation
- 1997-11-14 CA CA002268747A patent/CA2268747A1/en not_active Abandoned
- 1997-11-14 EA EA199900436A patent/EA002349B1/ru not_active IP Right Cessation
- 1997-11-14 EP EP97948362A patent/EP0942930B1/en not_active Expired - Lifetime
- 1997-11-14 KR KR1019997004281A patent/KR100554332B1/ko not_active IP Right Cessation
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1999
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- 1999-05-14 NO NO19992353A patent/NO327149B1/no not_active IP Right Cessation
- 1999-07-29 US US09/363,573 patent/US6184360B1/en not_active Expired - Lifetime
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2000
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2002
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2004
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2007
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2008
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