NO325453B1 - Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metylfenyl}-4-(3-pyridyl)-2-pyrimidinamin og et bifosfonat. - Google Patents
Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metylfenyl}-4-(3-pyridyl)-2-pyrimidinamin og et bifosfonat. Download PDFInfo
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- NO325453B1 NO325453B1 NO20034713A NO20034713A NO325453B1 NO 325453 B1 NO325453 B1 NO 325453B1 NO 20034713 A NO20034713 A NO 20034713A NO 20034713 A NO20034713 A NO 20034713A NO 325453 B1 NO325453 B1 NO 325453B1
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29142701P | 2001-05-16 | 2001-05-16 | |
| PCT/EP2002/005362 WO2002092091A1 (en) | 2001-05-16 | 2002-05-15 | Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20034713L NO20034713L (no) | 2003-10-21 |
| NO20034713D0 NO20034713D0 (no) | 2003-10-21 |
| NO325453B1 true NO325453B1 (no) | 2008-05-05 |
Family
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Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20034713A NO325453B1 (no) | 2001-05-16 | 2003-10-21 | Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metylfenyl}-4-(3-pyridyl)-2-pyrimidinamin og et bifosfonat. |
| NO20076323A NO20076323L (no) | 2001-05-16 | 2007-12-07 | Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metyl-fenyl}-4-(3-pyridyl)-2-pyrimidinamin og en aromataseinhibitor, anvendelse av kombinasjonen samt farmasøytisk preparat |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076323A NO20076323L (no) | 2001-05-16 | 2007-12-07 | Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metyl-fenyl}-4-(3-pyridyl)-2-pyrimidinamin og en aromataseinhibitor, anvendelse av kombinasjonen samt farmasøytisk preparat |
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| Country | Link |
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| US (3) | US20040167134A1 (enExample) |
| EP (2) | EP2253319A1 (enExample) |
| JP (2) | JP4477303B2 (enExample) |
| KR (2) | KR20030094415A (enExample) |
| CN (1) | CN1700917B (enExample) |
| AT (1) | ATE359790T1 (enExample) |
| AU (1) | AU2002342335B2 (enExample) |
| BR (1) | BR0209647A (enExample) |
| CA (1) | CA2444867C (enExample) |
| CO (1) | CO5540315A2 (enExample) |
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| DE (1) | DE60219617T2 (enExample) |
| DK (1) | DK1392313T3 (enExample) |
| EC (1) | ECSP034823A (enExample) |
| ES (1) | ES2283570T3 (enExample) |
| HU (1) | HUP0400038A3 (enExample) |
| IL (1) | IL158274A0 (enExample) |
| MX (1) | MXPA03010401A (enExample) |
| NO (2) | NO325453B1 (enExample) |
| NZ (1) | NZ529145A (enExample) |
| PL (2) | PL392652A1 (enExample) |
| PT (1) | PT1392313E (enExample) |
| RU (1) | RU2318517C2 (enExample) |
| SI (1) | SI1392313T1 (enExample) |
| SK (1) | SK14042003A3 (enExample) |
| WO (1) | WO2002092091A1 (enExample) |
| ZA (1) | ZA200307665B (enExample) |
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| KR100600550B1 (ko) | 2000-10-20 | 2006-07-13 | 에자이 가부시키가이샤 | 질소 함유 방향환 유도체 |
| GB0201882D0 (en) * | 2002-01-28 | 2002-03-13 | Novartis Ag | Organic compounds |
| AU2007201056B2 (en) * | 2002-01-28 | 2010-06-10 | Hyks-Instituutti Oy | Treatment of rheumatoid arthritis using imatinib |
| GB0202874D0 (en) * | 2002-02-07 | 2002-03-27 | Novartis Ag | Organic compounds |
| US20060094674A1 (en) * | 2002-07-05 | 2006-05-04 | Neel Benjamin G | Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms |
| EP1604665B1 (en) | 2003-03-10 | 2011-05-11 | Eisai R&D Management Co., Ltd. | C-kit kinase inhibitor |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| GB0311971D0 (en) * | 2003-05-23 | 2003-06-25 | Novartis Ag | Organic compounds |
| JP4303726B2 (ja) | 2003-11-11 | 2009-07-29 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ウレア誘導体およびその製造方法 |
| US8969379B2 (en) * | 2004-09-17 | 2015-03-03 | Eisai R&D Management Co., Ltd. | Pharmaceutical compositions of 4-(3-chloro-4-(cyclopropylaminocarbonyl)aminophenoxy)-7=methoxy-6-quinolinecarboxide |
| US20060235006A1 (en) * | 2005-04-13 | 2006-10-19 | Lee Francis Y | Combinations, methods and compositions for treating cancer |
| JP5066446B2 (ja) * | 2005-08-01 | 2012-11-07 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 血管新生阻害物質の効果を予測する方法 |
| JP4989476B2 (ja) | 2005-08-02 | 2012-08-01 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 血管新生阻害物質の効果を検定する方法 |
| US20080221126A1 (en) * | 2005-08-03 | 2008-09-11 | Atadja Peter W | Use of Hdac Inhibitors for the Treatment of Myeloma |
| EP3488866A1 (en) * | 2005-11-04 | 2019-05-29 | Wyeth LLC | Antineoplastic combinations with mtor inhibitor, herceptin, and/or hki-272 |
| KR101353763B1 (ko) | 2005-11-07 | 2014-01-21 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 혈관 신생 저해 물질과 ｃ―ｋｉｔ 키나아제 저해 물질의병용 |
| CN104706637A (zh) | 2006-05-18 | 2015-06-17 | 卫材R&D管理有限公司 | 针对甲状腺癌的抗肿瘤剂 |
| CN1899616A (zh) * | 2006-07-20 | 2007-01-24 | 中国人民解放军军事医学科学院生物工程研究所 | 非受体酪氨酸激酶c－Abl特异性抑制剂的新用途 |
| JP5368096B2 (ja) | 2006-08-28 | 2013-12-18 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 未分化型胃癌に対する抗腫瘍剤 |
| WO2008093855A1 (ja) | 2007-01-29 | 2008-08-07 | Eisai R & D Management Co., Ltd. | 未分化型胃癌治療用組成物 |
| CA2704000C (en) * | 2007-11-09 | 2016-12-13 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
| WO2009096377A1 (ja) * | 2008-01-29 | 2009-08-06 | Eisai R & D Management Co., Ltd. | 血管阻害物質とタキサンとの併用 |
| ES2531322T3 (es) * | 2008-06-17 | 2015-03-13 | Wyeth Llc | Combinaciones antineoplásicas que contienen HKI-272 y vinorelbina |
| CA2771403C (en) | 2009-08-19 | 2015-02-24 | Eisai R&D Management Co. Ltd. | Quinoline derivative-containing pharmaceutical composition |
| CN102958523B (zh) | 2010-06-25 | 2014-11-19 | 卫材R&D管理有限公司 | 使用具有激酶抑制作用的组合的抗肿瘤剂 |
| AU2012246490B2 (en) | 2011-04-18 | 2016-08-04 | Eisai R&D Management Co., Ltd. | Therapeutic agent for tumor |
| JP6038128B2 (ja) | 2011-06-03 | 2016-12-07 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | レンバチニブ化合物に対する甲状腺癌対象及び腎臓癌対象の反応性を予測及び評価するためのバイオマーカー |
| JPWO2014098176A1 (ja) | 2012-12-21 | 2017-01-12 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | キノリン誘導体のアモルファス及びその製造方法 |
| CA2912219C (en) | 2013-05-14 | 2021-11-16 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of endometrial cancer subjects to lenvatinib compounds |
| EP3187491A4 (en) | 2014-08-28 | 2018-08-01 | Eisai R&D Management Co., Ltd. | High-purity quinoline derivative and method for manufacturing same |
| US20180028662A1 (en) | 2015-02-25 | 2018-02-01 | Eisai R&D Management Co., Ltd. | Method for Suppressing Bitterness of Quinoline Derivative |
| KR20240064733A (ko) | 2015-03-04 | 2024-05-13 | 머크 샤프 앤드 돔 코포레이션 | 암을 치료하기 위한 pd-1 길항제 및 vegfr/fgfr/ret 티로신 키나제 억제제의 조합 |
| CA2988707C (en) | 2015-06-16 | 2023-10-10 | Eisai R&D Management Co., Ltd. | Combination of cbp/catenin inhibitor and immune checkpoint inhibitor for treating cancer |
| CN108135894B (zh) | 2015-08-20 | 2021-02-19 | 卫材R&D管理有限公司 | 肿瘤治疗剂 |
| CN110072528B (zh) | 2017-02-08 | 2022-04-26 | 卫材R&D管理有限公司 | 治疗肿瘤的药物组合物 |
| WO2018212202A1 (en) | 2017-05-16 | 2018-11-22 | Eisai R&D Management Co., Ltd. | Treatment of hepatocellular carcinoma |
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2002
- 2002-05-15 AU AU2002342335A patent/AU2002342335B2/en not_active Ceased
- 2002-05-15 CZ CZ20033098A patent/CZ299756B6/cs not_active IP Right Cessation
- 2002-05-15 HU HU0400038A patent/HUP0400038A3/hu unknown
- 2002-05-15 EP EP10173158A patent/EP2253319A1/en not_active Withdrawn
- 2002-05-15 RU RU2003135786/14A patent/RU2318517C2/ru not_active IP Right Cessation
- 2002-05-15 SI SI200230560T patent/SI1392313T1/sl unknown
- 2002-05-15 JP JP2002589008A patent/JP4477303B2/ja not_active Expired - Lifetime
- 2002-05-15 CN CN028093623A patent/CN1700917B/zh not_active Expired - Fee Related
- 2002-05-15 IL IL15827402A patent/IL158274A0/xx unknown
- 2002-05-15 KR KR10-2003-7014844A patent/KR20030094415A/ko not_active Abandoned
- 2002-05-15 PL PL392652A patent/PL392652A1/pl unknown
- 2002-05-15 EP EP02743024A patent/EP1392313B1/en not_active Expired - Lifetime
- 2002-05-15 ES ES02743024T patent/ES2283570T3/es not_active Expired - Lifetime
- 2002-05-15 NZ NZ529145A patent/NZ529145A/en unknown
- 2002-05-15 SK SK1404-2003A patent/SK14042003A3/sk not_active Application Discontinuation
- 2002-05-15 CA CA2444867A patent/CA2444867C/en not_active Expired - Fee Related
- 2002-05-15 US US10/476,817 patent/US20040167134A1/en not_active Abandoned
- 2002-05-15 DE DE60219617T patent/DE60219617T2/de not_active Expired - Fee Related
- 2002-05-15 WO PCT/EP2002/005362 patent/WO2002092091A1/en not_active Ceased
- 2002-05-15 BR BR0209647-1A patent/BR0209647A/pt not_active IP Right Cessation
- 2002-05-15 PT PT02743024T patent/PT1392313E/pt unknown
- 2002-05-15 MX MXPA03010401A patent/MXPA03010401A/es active IP Right Grant
- 2002-05-15 AT AT02743024T patent/ATE359790T1/de not_active IP Right Cessation
- 2002-05-15 KR KR1020087023228A patent/KR20080091866A/ko not_active Ceased
- 2002-05-15 PL PL02368068A patent/PL368068A1/xx unknown
- 2002-05-15 DK DK02743024T patent/DK1392313T3/da active
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2003
- 2003-10-01 ZA ZA200307665A patent/ZA200307665B/en unknown
- 2003-10-21 NO NO20034713A patent/NO325453B1/no not_active IP Right Cessation
- 2003-10-29 EC EC2003004823A patent/ECSP034823A/es unknown
- 2003-11-06 CO CO03098325A patent/CO5540315A2/es not_active Application Discontinuation
-
2007
- 2007-12-07 NO NO20076323A patent/NO20076323L/no not_active Application Discontinuation
-
2009
- 2009-04-14 US US12/423,079 patent/US20090202541A1/en not_active Abandoned
- 2009-12-11 JP JP2009281667A patent/JP2010059202A/ja not_active Ceased
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2012
- 2012-07-17 US US13/551,079 patent/US20120283206A1/en not_active Abandoned
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