NO325453B1 - Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metylfenyl}-4-(3-pyridyl)-2-pyrimidinamin og et bifosfonat. - Google Patents
Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metylfenyl}-4-(3-pyridyl)-2-pyrimidinamin og et bifosfonat. Download PDFInfo
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- NO325453B1 NO325453B1 NO20034713A NO20034713A NO325453B1 NO 325453 B1 NO325453 B1 NO 325453B1 NO 20034713 A NO20034713 A NO 20034713A NO 20034713 A NO20034713 A NO 20034713A NO 325453 B1 NO325453 B1 NO 325453B1
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29142701P | 2001-05-16 | 2001-05-16 | |
| PCT/EP2002/005362 WO2002092091A1 (en) | 2001-05-16 | 2002-05-15 | Combination comprising n-{5-[4-(4-methyl-piperazino-methyl)-benzoylamido]-2-methylphenyl}-4-(3-pyridyl)-2pyrimidine-amine and a chemotherapeutic agent |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20034713L NO20034713L (no) | 2003-10-21 |
| NO20034713D0 NO20034713D0 (no) | 2003-10-21 |
| NO325453B1 true NO325453B1 (no) | 2008-05-05 |
Family
ID=23120246
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20034713A NO325453B1 (no) | 2001-05-16 | 2003-10-21 | Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metylfenyl}-4-(3-pyridyl)-2-pyrimidinamin og et bifosfonat. |
| NO20076323A NO20076323L (no) | 2001-05-16 | 2007-12-07 | Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metyl-fenyl}-4-(3-pyridyl)-2-pyrimidinamin og en aromataseinhibitor, anvendelse av kombinasjonen samt farmasøytisk preparat |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20076323A NO20076323L (no) | 2001-05-16 | 2007-12-07 | Kombinasjon omfattende N-{5-[4-(4-metylpiperazinometyl)-benzoylamido]-2-metyl-fenyl}-4-(3-pyridyl)-2-pyrimidinamin og en aromataseinhibitor, anvendelse av kombinasjonen samt farmasøytisk preparat |
Country Status (28)
| Country | Link |
|---|---|
| US (3) | US20040167134A1 (da) |
| EP (2) | EP1392313B1 (da) |
| JP (2) | JP4477303B2 (da) |
| KR (2) | KR20080091866A (da) |
| CN (1) | CN1700917B (da) |
| AT (1) | ATE359790T1 (da) |
| AU (1) | AU2002342335B2 (da) |
| BR (1) | BR0209647A (da) |
| CA (1) | CA2444867C (da) |
| CO (1) | CO5540315A2 (da) |
| CZ (1) | CZ299756B6 (da) |
| DE (1) | DE60219617T2 (da) |
| DK (1) | DK1392313T3 (da) |
| EC (1) | ECSP034823A (da) |
| ES (1) | ES2283570T3 (da) |
| HK (1) | HK1062895A1 (da) |
| HU (1) | HUP0400038A3 (da) |
| IL (1) | IL158274A0 (da) |
| MX (1) | MXPA03010401A (da) |
| NO (2) | NO325453B1 (da) |
| NZ (1) | NZ529145A (da) |
| PL (2) | PL392652A1 (da) |
| PT (1) | PT1392313E (da) |
| RU (1) | RU2318517C2 (da) |
| SI (1) | SI1392313T1 (da) |
| SK (1) | SK14042003A3 (da) |
| WO (1) | WO2002092091A1 (da) |
| ZA (1) | ZA200307665B (da) |
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| GB0201882D0 (en) * | 2002-01-28 | 2002-03-13 | Novartis Ag | Organic compounds |
| AU2007201056B2 (en) * | 2002-01-28 | 2010-06-10 | Hyks-Instituutti Oy | Treatment of rheumatoid arthritis using imatinib |
| GB0202874D0 (en) * | 2002-02-07 | 2002-03-27 | Novartis Ag | Organic compounds |
| WO2004004644A2 (en) * | 2002-07-05 | 2004-01-15 | Beth Israel Deaconess Medical Center | Combination of mtor inhibitor and a tyrosine kinase inhibitor for the treatment of neoplasms |
| EP1604665B1 (en) | 2003-03-10 | 2011-05-11 | Eisai R&D Management Co., Ltd. | C-kit kinase inhibitor |
| US20050043233A1 (en) | 2003-04-29 | 2005-02-24 | Boehringer Ingelheim International Gmbh | Combinations for the treatment of diseases involving cell proliferation, migration or apoptosis of myeloma cells or angiogenesis |
| GB0311971D0 (en) * | 2003-05-23 | 2003-06-25 | Novartis Ag | Organic compounds |
| US7683172B2 (en) | 2003-11-11 | 2010-03-23 | Eisai R&D Management Co., Ltd. | Urea derivative and process for preparing the same |
| WO2006030826A1 (ja) | 2004-09-17 | 2006-03-23 | Eisai R & D Management Co., Ltd. | 医薬組成物 |
| US20060235006A1 (en) * | 2005-04-13 | 2006-10-19 | Lee Francis Y | Combinations, methods and compositions for treating cancer |
| WO2007015569A1 (ja) * | 2005-08-01 | 2007-02-08 | Eisai R & D Management Co., Ltd. | 血管新生阻害物質の効果を予測する方法 |
| EP1925676A4 (en) | 2005-08-02 | 2010-11-10 | Eisai R&D Man Co Ltd | TEST METHOD FOR THE EFFECT OF A VASCULARIZATION INHIBITOR |
| JP5665271B2 (ja) * | 2005-08-03 | 2015-02-04 | ノバルティス アーゲー | 骨髄腫の処置のためのｈｄａｃ阻害剤の使用 |
| AU2006311877A1 (en) * | 2005-11-04 | 2007-05-18 | Wyeth Llc | Antineoplastic combinations with mTOR inhibitor, herceptin, and/orHKI-272 |
| JPWO2007052849A1 (ja) | 2005-11-07 | 2009-04-30 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 血管新生阻害物質とｃ−ｋｉｔキナーゼ阻害物質との併用 |
| WO2007136103A1 (ja) | 2006-05-18 | 2007-11-29 | Eisai R & D Management Co., Ltd. | 甲状腺癌に対する抗腫瘍剤 |
| CN1899616A (zh) * | 2006-07-20 | 2007-01-24 | 中国人民解放军军事医学科学院生物工程研究所 | 非受体酪氨酸激酶c－Abl特异性抑制剂的新用途 |
| WO2008026748A1 (fr) * | 2006-08-28 | 2008-03-06 | Eisai R & D Management Co., Ltd. | Agent antitumoral pour cancer gastrique non différencié |
| CN101600694A (zh) | 2007-01-29 | 2009-12-09 | 卫材R&D管理有限公司 | 未分化型胃癌治疗用组合物 |
| CA2704000C (en) * | 2007-11-09 | 2016-12-13 | Eisai R&D Management Co., Ltd. | Combination of anti-angiogenic substance and anti-tumor platinum complex |
| CA2713930A1 (en) * | 2008-01-29 | 2009-08-06 | Eisai R & D Management Co., Ltd. | Combined use of angiogenesis inhibitor and taxane |
| KR20180128078A (ko) * | 2008-06-17 | 2018-11-30 | 와이어쓰 엘엘씨 | Ｈｋｉ-272 및 비노렐빈을 함유하는 항신생물성 조합물 |
| MX2012014776A (es) | 2010-06-25 | 2013-01-29 | Eisai R&D Man Co Ltd | Agente antitumoral que emplea compuestos con efecto inhibidor de cinasas combinados. |
| AU2012246490B2 (en) | 2011-04-18 | 2016-08-04 | Eisai R&D Management Co., Ltd. | Therapeutic agent for tumor |
| EP2714937B1 (en) | 2011-06-03 | 2018-11-14 | Eisai R&D Management Co., Ltd. | Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds |
| KR20150098605A (ko) | 2012-12-21 | 2015-08-28 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 퀴놀린 유도체의 비정질 형태 및 그의 제조방법 |
| JP6411379B2 (ja) | 2013-05-14 | 2018-10-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | レンバチニブ化合物に対する子宮内膜がん対象の応答性を予測及び評価するためのバイオマーカー |
| ES2926687T3 (es) | 2014-08-28 | 2022-10-27 | Eisai R&D Man Co Ltd | Derivado de quinolina muy puro y método para su producción |
| US20180028662A1 (en) | 2015-02-25 | 2018-02-01 | Eisai R&D Management Co., Ltd. | Method for Suppressing Bitterness of Quinoline Derivative |
| CA2978226A1 (en) | 2015-03-04 | 2016-09-09 | Merck Sharpe & Dohme Corp. | Combination of a pd-1 antagonist and a vegfr/fgfr/ret tyrosine kinase inhibitor for treating cancer |
| CA2988707C (en) | 2015-06-16 | 2023-10-10 | Eisai R&D Management Co., Ltd. | Combination of cbp/catenin inhibitor and immune checkpoint inhibitor for treating cancer |
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-
2002
- 2002-05-15 PL PL392652A patent/PL392652A1/pl unknown
- 2002-05-15 PT PT02743024T patent/PT1392313E/pt unknown
- 2002-05-15 CN CN028093623A patent/CN1700917B/zh not_active Expired - Fee Related
- 2002-05-15 AU AU2002342335A patent/AU2002342335B2/en not_active Ceased
- 2002-05-15 JP JP2002589008A patent/JP4477303B2/ja not_active Expired - Lifetime
- 2002-05-15 SI SI200230560T patent/SI1392313T1/sl unknown
- 2002-05-15 NZ NZ529145A patent/NZ529145A/en unknown
- 2002-05-15 EP EP02743024A patent/EP1392313B1/en not_active Expired - Lifetime
- 2002-05-15 PL PL02368068A patent/PL368068A1/xx unknown
- 2002-05-15 DK DK02743024T patent/DK1392313T3/da active
- 2002-05-15 KR KR1020087023228A patent/KR20080091866A/ko not_active Application Discontinuation
- 2002-05-15 SK SK1404-2003A patent/SK14042003A3/sk not_active Application Discontinuation
- 2002-05-15 MX MXPA03010401A patent/MXPA03010401A/es active IP Right Grant
- 2002-05-15 CA CA2444867A patent/CA2444867C/en not_active Expired - Fee Related
- 2002-05-15 DE DE60219617T patent/DE60219617T2/de not_active Expired - Fee Related
- 2002-05-15 IL IL15827402A patent/IL158274A0/xx unknown
- 2002-05-15 EP EP10173158A patent/EP2253319A1/en not_active Withdrawn
- 2002-05-15 KR KR10-2003-7014844A patent/KR20030094415A/ko active Search and Examination
- 2002-05-15 AT AT02743024T patent/ATE359790T1/de not_active IP Right Cessation
- 2002-05-15 HU HU0400038A patent/HUP0400038A3/hu unknown
- 2002-05-15 RU RU2003135786/14A patent/RU2318517C2/ru not_active IP Right Cessation
- 2002-05-15 US US10/476,817 patent/US20040167134A1/en not_active Abandoned
- 2002-05-15 BR BR0209647-1A patent/BR0209647A/pt not_active IP Right Cessation
- 2002-05-15 ES ES02743024T patent/ES2283570T3/es not_active Expired - Lifetime
- 2002-05-15 CZ CZ20033098A patent/CZ299756B6/cs not_active IP Right Cessation
- 2002-05-15 WO PCT/EP2002/005362 patent/WO2002092091A1/en active Application Filing
-
2003
- 2003-10-01 ZA ZA200307665A patent/ZA200307665B/en unknown
- 2003-10-21 NO NO20034713A patent/NO325453B1/no not_active IP Right Cessation
- 2003-10-29 EC EC2003004823A patent/ECSP034823A/es unknown
- 2003-11-06 CO CO03098325A patent/CO5540315A2/es not_active Application Discontinuation
-
2004
- 2004-08-05 HK HK04105830A patent/HK1062895A1/xx not_active IP Right Cessation
-
2007
- 2007-12-07 NO NO20076323A patent/NO20076323L/no not_active Application Discontinuation
-
2009
- 2009-04-14 US US12/423,079 patent/US20090202541A1/en not_active Abandoned
- 2009-12-11 JP JP2009281667A patent/JP2010059202A/ja not_active Ceased
-
2012
- 2012-07-17 US US13/551,079 patent/US20120283206A1/en not_active Abandoned
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