NO317989B1 - Nye dipeptidylpeptidase IV effektorer og anvendelse derav, samt farmasoytisk preparat - Google Patents
Nye dipeptidylpeptidase IV effektorer og anvendelse derav, samt farmasoytisk preparat Download PDFInfo
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- NO317989B1 NO317989B1 NO20005994A NO20005994A NO317989B1 NO 317989 B1 NO317989 B1 NO 317989B1 NO 20005994 A NO20005994 A NO 20005994A NO 20005994 A NO20005994 A NO 20005994A NO 317989 B1 NO317989 B1 NO 317989B1
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- pharmaceutical preparation
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- dipeptide
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- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
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DE19823831A DE19823831A1 (de) | 1998-05-28 | 1998-05-28 | Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen |
PCT/EP1999/003712 WO1999061431A1 (de) | 1998-05-28 | 1999-05-28 | Neue effektoren von dipeptidylpeptidase iv |
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NO20005994D0 NO20005994D0 (no) | 2000-11-27 |
NO20005994L NO20005994L (no) | 2001-01-25 |
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NO20005994A NO317989B1 (no) | 1998-05-28 | 2000-11-27 | Nye dipeptidylpeptidase IV effektorer og anvendelse derav, samt farmasoytisk preparat |
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EP (6) | EP1304327B1 (zh) |
JP (1) | JP2002516318A (zh) |
KR (2) | KR100628668B1 (zh) |
CN (4) | CN101095675A (zh) |
AT (6) | ATE338546T1 (zh) |
AU (1) | AU764262B2 (zh) |
BR (1) | BR9910758A (zh) |
CA (1) | CA2333603C (zh) |
DE (10) | DE19823831A1 (zh) |
DK (2) | DK1304327T3 (zh) |
ES (5) | ES2271458T3 (zh) |
HK (3) | HK1033316A1 (zh) |
HU (1) | HUP0102001A3 (zh) |
IL (3) | IL139862A0 (zh) |
IS (3) | IS5728A (zh) |
NO (1) | NO317989B1 (zh) |
NZ (2) | NZ525799A (zh) |
PL (1) | PL344403A1 (zh) |
PT (2) | PT1214936E (zh) |
RU (3) | RU2309161C2 (zh) |
SI (2) | SI1082314T1 (zh) |
UA (1) | UA54599C2 (zh) |
WO (1) | WO1999061431A1 (zh) |
Families Citing this family (242)
Publication number | Priority date | Publication date | Assignee | Title |
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US20020006899A1 (en) * | 1998-10-06 | 2002-01-17 | Pospisilik Andrew J. | Use of dipeptidyl peptidase IV effectors for lowering blood pressure in mammals |
CN1163594C (zh) * | 1997-09-29 | 2004-08-25 | 尖端医疗有限公司 | 体外造血细胞的刺激 |
DE19823831A1 (de) * | 1998-05-28 | 1999-12-02 | Probiodrug Ges Fuer Arzneim | Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen |
DE19828113A1 (de) | 1998-06-24 | 2000-01-05 | Probiodrug Ges Fuer Arzneim | Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV |
DE19834591A1 (de) * | 1998-07-31 | 2000-02-03 | Probiodrug Ges Fuer Arzneim | Verfahren zur Steigerung des Blutglukosespiegels in Säugern |
US6979697B1 (en) * | 1998-08-21 | 2005-12-27 | Point Therapeutics, Inc. | Regulation of substrate activity |
US20030176357A1 (en) * | 1998-10-06 | 2003-09-18 | Pospisilik Andrew J. | Dipeptidyl peptidase IV inhibitors and their uses for lowering blood pressure levels |
WO2000053171A1 (en) * | 1999-03-05 | 2000-09-14 | Molteni L. E C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A. | Use of metformin in the preparation of pharmaceutical compositions capable of inhibiting the enzyme dipeptidyl peptidase iv |
US6548529B1 (en) | 1999-04-05 | 2003-04-15 | Bristol-Myers Squibb Company | Heterocyclic containing biphenyl aP2 inhibitors and method |
US6890904B1 (en) * | 1999-05-25 | 2005-05-10 | Point Therapeutics, Inc. | Anti-tumor agents |
DE19940130A1 (de) | 1999-08-24 | 2001-03-01 | Probiodrug Ges Fuer Arzneim | Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung |
AU2268401A (en) * | 1999-12-17 | 2001-06-25 | Versicor Inc | Novel succinate compounds, compositions and methods of use and preparation |
AU2001237321A1 (en) * | 2000-01-21 | 2001-07-31 | Novartis Ag | Combinations comprising dipeptidylpeptidase - iv inhibitor |
US20080076811A1 (en) * | 2000-01-21 | 2008-03-27 | Bork Balkan | Combinations comprising depeptidypeptidase-iv inhibitors and antidiabetic agents |
JP2003523396A (ja) * | 2000-02-25 | 2003-08-05 | ノボ ノルディスク アクティーゼルスカブ | ベータ細胞変性の抑制 |
IL151368A0 (en) * | 2000-03-31 | 2003-04-10 | Probiodrug Ag | Use of a dipeptidyl peptidase iv enzyme activity effector for the production of pharmaceutical compositions |
GB0010183D0 (en) * | 2000-04-26 | 2000-06-14 | Ferring Bv | Inhibitors of dipeptidyl peptidase IV |
US7078397B2 (en) | 2000-06-19 | 2006-07-18 | Smithkline Beecham Corporation | Combinations of dipeptidyl peptidase IV inhibitors and other antidiabetic agents for the treatment of diabetes mellitus |
GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
HU227882B1 (hu) | 2000-08-10 | 2012-05-29 | Mitsubishi Tanabe Pharma Corp | Prolinszármazékok és gyógyszerként való alkalmazásuk |
EP1891948A1 (en) | 2000-10-27 | 2008-02-27 | Probiodrug AG | Treatment of neurological and neuropsychological disorders |
CA2689012A1 (en) * | 2000-10-27 | 2002-05-02 | Probiodrug Ag | Method for the treatment of neurological and neuropsychological disorders |
US7132104B1 (en) | 2000-10-27 | 2006-11-07 | Probiodrug Ag | Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders |
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