US5614492A
(en)
*
|
1986-05-05 |
1997-03-25 |
The General Hospital Corporation |
Insulinotropic hormone GLP-1 (7-36) and uses thereof
|
US6849708B1
(en)
|
1986-05-05 |
2005-02-01 |
The General Hospital Corporation |
Insulinotropic hormone and uses thereof
|
US7138486B2
(en)
|
1986-05-05 |
2006-11-21 |
The General Hospital Corporation |
Insulinotropic hormone derivatives and uses thereof
|
DK36492D0
(da)
*
|
1992-03-19 |
1992-03-19 |
Novo Nordisk As |
Praeparat
|
USRE37302E1
(en)
*
|
1992-03-19 |
2001-07-31 |
Novo Nordisk A/S |
Peptide
|
DK36392D0
(da)
*
|
1992-03-19 |
1992-03-19 |
Novo Nordisk As |
Anvendelse af kemisk forbindelse
|
RU2128663C1
(ru)
*
|
1992-06-15 |
1999-04-10 |
Скиос Инк. |
Производные полипептида, обладающие инсулинотропной активностью, фармацевтическая композиция, способы усиления действия инсулина, способы лечения диабета
|
NZ250844A
(en)
*
|
1993-04-07 |
1996-03-26 |
Pfizer |
Treatment of non-insulin dependant diabetes with peptides; composition
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
US5705483A
(en)
*
|
1993-12-09 |
1998-01-06 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptides, compositions and methods
|
EP0658568A1
(en)
*
|
1993-12-09 |
1995-06-21 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptides, compositions and methods
|
DK144093D0
(da)
*
|
1993-12-23 |
1993-12-23 |
Novo Nordisk As |
|
GB9409496D0
(en)
*
|
1994-05-12 |
1994-06-29 |
London Health Ass |
Method for improving glycaemic control in diabetes
|
US5574008A
(en)
*
|
1994-08-30 |
1996-11-12 |
Eli Lilly And Company |
Biologically active fragments of glucagon-like insulinotropic peptide
|
US5512549A
(en)
|
1994-10-18 |
1996-04-30 |
Eli Lilly And Company |
Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
|
US5990077A
(en)
*
|
1995-04-14 |
1999-11-23 |
1149336 Ontario Inc. |
Glucagon-like peptide-2 and its therapeutic use
|
WO1996036883A1
(en)
*
|
1995-05-17 |
1996-11-21 |
Novo Nordisk A/S |
Immunoassay for glucagon like protein 1 (glp-1) in plasma
|
US6852690B1
(en)
|
1995-08-22 |
2005-02-08 |
Amylin Pharmaceuticals, Inc. |
Method and composition for enhanced parenteral nutrition
|
DE19616486C5
(de)
*
|
1996-04-25 |
2016-06-30 |
Royalty Pharma Collection Trust |
Verfahren zur Senkung des Blutglukosespiegels in Säugern
|
US6268343B1
(en)
|
1996-08-30 |
2001-07-31 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
US6458924B2
(en)
|
1996-08-30 |
2002-10-01 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
US6006753A
(en)
*
|
1996-08-30 |
1999-12-28 |
Eli Lilly And Company |
Use of GLP-1 or analogs to abolish catabolic changes after surgery
|
US6277819B1
(en)
*
|
1996-08-30 |
2001-08-21 |
Eli Lilly And Company |
Use of GLP-1 or analogs in treatment of myocardial infarction
|
WO1998008872A1
(en)
*
|
1996-08-30 |
1998-03-05 |
Novo Nordisk A/S |
Glp-2 derivatives
|
PT944648E
(pt)
*
|
1996-08-30 |
2007-06-26 |
Novo Nordisk As |
Derivados do glp-1.
|
US7235627B2
(en)
|
1996-08-30 |
2007-06-26 |
Novo Nordisk A/S |
Derivatives of GLP-1 analogs
|
EP1566180A3
(en)
*
|
1996-08-30 |
2007-08-08 |
Eli Lilly & Company |
Use of GLP-1 or Analogs in Treatment of Myocardial Infarction
|
UA65549C2
(uk)
|
1996-11-05 |
2004-04-15 |
Елі Ліллі Енд Компані |
Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
|
ATE304864T1
(de)
|
1997-01-07 |
2005-10-15 |
Amylin Pharmaceuticals Inc |
Verwendung von exedinen und deren antagonisten zur verminderung der lebensmittelaufnahme
|
JP2002510193A
(ja)
*
|
1997-03-31 |
2002-04-02 |
イーライ・リリー・アンド・カンパニー |
グルカゴン様ペプチド−1類似体
|
US7157555B1
(en)
|
1997-08-08 |
2007-01-02 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
ES2222613T3
(es)
*
|
1997-09-12 |
2005-02-01 |
Pharis Biotec Gmbh |
Composicion para la terapia de diabetes mellitus y de la obesidad.
|
US7223725B1
(en)
|
1997-11-14 |
2007-05-29 |
Amylin Pharmaceuticals, Inc. |
Exendin agonist compounds
|
MXPA00004670A
(es)
|
1997-11-14 |
2003-07-14 |
Amylin Pharmaceuticals Inc |
Compuestos agonistas de exendina novedosos.
|
CA2312190A1
(en)
*
|
1997-12-05 |
1999-06-17 |
Eli Lilly And Company |
Glp-1 formulations
|
EP2574336A1
(en)
|
1998-02-02 |
2013-04-03 |
Trustees Of Tufts College |
Use of dipeptidylpeptidase inhibitors to regulate glucose metabolism
|
JP2002504518A
(ja)
*
|
1998-02-27 |
2002-02-12 |
ノボ ノルディスク アクティーゼルスカブ |
部分的に構造化されたミセルー様凝集体を形成する、25%を超えるヘリックス−含有率を有するglp−1誘導体
|
JP2002506792A
(ja)
|
1998-02-27 |
2002-03-05 |
ノボ ノルディスク アクティーゼルスカブ |
N末端修飾glp−1誘導体
|
AU3247799A
(en)
|
1998-02-27 |
1999-09-15 |
Novo Nordisk A/S |
Glp-1 derivatives of glp-1 and exendin with protracted profile of action
|
FR2777283B1
(fr)
*
|
1998-04-10 |
2000-11-24 |
Adir |
Nouveaux composes peptidiques analogues du glucagon-peptide- 1 (7-37), leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
JPH11328947A
(ja)
|
1998-05-18 |
1999-11-30 |
Nec Corp |
大規模fifo回路
|
DE19823831A1
(de)
|
1998-05-28 |
1999-12-02 |
Probiodrug Ges Fuer Arzneim |
Neue pharmazeutische Verwendung von Isoleucyl Thiazolidid und seinen Salzen
|
DE19828114A1
(de)
|
1998-06-24 |
2000-01-27 |
Probiodrug Ges Fuer Arzneim |
Produgs instabiler Inhibitoren der Dipeptidyl Peptidase IV
|
DE19828113A1
(de)
|
1998-06-24 |
2000-01-05 |
Probiodrug Ges Fuer Arzneim |
Prodrugs von Inhibitoren der Dipeptidyl Peptidase IV
|
EP1932535A3
(en)
|
1998-07-31 |
2008-10-29 |
Novo Nordisk A/S |
Stimulation of beta cell profileration
|
EP1666054A1
(en)
|
1998-08-28 |
2006-06-07 |
Eli Lilly & Company |
Method for administering insulinotropic peptides
|
WO2000015224A1
(en)
|
1998-09-17 |
2000-03-23 |
Eli Lilly And Company |
Protein formulations
|
US6461834B1
(en)
|
1998-11-06 |
2002-10-08 |
Bionebraska, Inc. |
Clostripain catalyzed amidation of peptides
|
EP1359159A3
(en)
*
|
1998-12-07 |
2004-07-21 |
Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S. |
Analogues of GLP-1
|
CZ303120B6
(cs)
*
|
1998-12-07 |
2012-04-11 |
Societe De Conseils De Recherches Et Dapplications Scientifiques S. A. |
Sloucenina a farmaceutický prostredek
|
BR9915961A
(pt)
|
1998-12-07 |
2001-08-21 |
Sod Conseils Rech Applic |
Análogos de glp-1
|
US7425541B2
(en)
|
1998-12-11 |
2008-09-16 |
Medarex, Inc. |
Enzyme-cleavable prodrug compounds
|
SI1140148T1
(sl)
|
1998-12-22 |
2006-04-30 |
Lilly Co Eli |
Stabilna formulacija raztopine glukagonu podobnega peptida-1
|
US6927214B1
(en)
|
1999-01-15 |
2005-08-09 |
Novo Nordisk A/S |
Non-peptide GLP-1 agonists
|
WO2000055203A1
(en)
*
|
1999-03-15 |
2000-09-21 |
Novo Nordisk A/S |
Ion exchange chromatographic separation of glp-1 and related peptides
|
US6451987B1
(en)
|
1999-03-15 |
2002-09-17 |
Novo Nordisk A/S |
Ion exchange chromatography of proteins and peptides
|
US6444788B1
(en)
|
1999-03-15 |
2002-09-03 |
Novo Nordisk A/S |
Ion exchange chromatography of GLP-1, analogs and derivatives thereof
|
US6451974B1
(en)
|
1999-03-17 |
2002-09-17 |
Novo Nordisk A/S |
Method of acylating peptides and novel acylating agents
|
US20050272652A1
(en)
|
1999-03-29 |
2005-12-08 |
Gault Victor A |
Peptide analogues of GIP for treatment of diabetes, insulin resistance and obesity
|
US6514500B1
(en)
|
1999-10-15 |
2003-02-04 |
Conjuchem, Inc. |
Long lasting synthetic glucagon like peptide {GLP-!}
|
DK1180121T3
(da)
|
1999-05-17 |
2004-03-01 |
Conjuchem Inc |
Langtidsvirkende insulinotrope peptider
|
US6309633B1
(en)
*
|
1999-06-19 |
2001-10-30 |
Nobex Corporation |
Amphiphilic drug-oligomer conjugates with hydroyzable lipophile components and methods for making and using the same
|
DE19940130A1
(de)
|
1999-08-24 |
2001-03-01 |
Probiodrug Ges Fuer Arzneim |
Neue Effektoren der Dipeptidyl Peptidase IV zur topischen Anwendung
|
IL149679A0
(en)
*
|
1999-11-19 |
2002-11-10 |
Transkaryotic Therapies Inc |
Nucleic acid construct and methods utilizing the same
|
DE122008000018I1
(de)
|
2000-01-21 |
2008-08-14 |
Novartis Pharma Ag |
Zusammensetzungen bestehend aus Dipeptidylpeptidase-IV Inhibitoren und Antidiabetica
|
DE60114996T2
(de)
|
2000-03-08 |
2006-08-10 |
Novo Nordisk A/S |
Senkung des serum cholesterols
|
BR0111562A
(pt)
|
2000-06-16 |
2003-04-15 |
Lilly Co Eli |
Análogos de peptìdeo 1 semelhantes ao glucagon
|
AR033390A1
(es)
|
2000-08-22 |
2003-12-17 |
Novartis Ag |
Una composicion farmaceutica que comprende un antagonista del receptor at1 y un potenciador de la secrecion de insulina, el uso de dicha composicion para la fabricacion de un medicamento y un kit de partes
|
EP1970072A1
(en)
|
2000-09-18 |
2008-09-17 |
Sanos Bioscience A/S |
Use of GLP-2 peptides for the treatment of hyperparathyroidism
|
US7132104B1
(en)
|
2000-10-27 |
2006-11-07 |
Probiodrug Ag |
Modulation of central nervous system (CNS) dipeptidyl peptidase IV (DPIV) -like activity for the treatment of neurological and neuropsychological disorders
|
US7090869B2
(en)
|
2000-12-01 |
2006-08-15 |
Takeda Pharmaceutical Company Limited |
Method for producing preparation containing bioactive substance
|
EP1351984A2
(en)
|
2000-12-13 |
2003-10-15 |
Eli Lilly And Company |
Amidated glucagon-like peptide-1
|
US6573237B2
(en)
|
2001-03-16 |
2003-06-03 |
Eli Lilly And Company |
Protein formulations
|
US6890905B2
(en)
|
2001-04-02 |
2005-05-10 |
Prosidion Limited |
Methods for improving islet signaling in diabetes mellitus and for its prevention
|
CN1162446C
(zh)
|
2001-05-10 |
2004-08-18 |
上海华谊生物技术有限公司 |
促胰岛素分泌肽衍生物
|
DE10150203A1
(de)
|
2001-10-12 |
2003-04-17 |
Probiodrug Ag |
Peptidylketone als Inhibitoren der DPIV
|
US20030130199A1
(en)
|
2001-06-27 |
2003-07-10 |
Von Hoersten Stephan |
Dipeptidyl peptidase IV inhibitors and their uses as anti-cancer agents
|
US7368421B2
(en)
|
2001-06-27 |
2008-05-06 |
Probiodrug Ag |
Use of dipeptidyl peptidase IV inhibitors in the treatment of multiple sclerosis
|
EP1432730A4
(en)
|
2001-08-23 |
2006-10-11 |
Lilly Co Eli |
GLP-1 ANALOGUES (GLUCAGON-LIKE PEPTIDE 1)
|
US6844316B2
(en)
|
2001-09-06 |
2005-01-18 |
Probiodrug Ag |
Inhibitors of dipeptidyl peptidase I
|
US6864069B2
(en)
|
2001-10-05 |
2005-03-08 |
Bayer Pharmaceuticals Corporation |
Peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists and their pharmacological methods of use
|
AR036711A1
(es)
|
2001-10-05 |
2004-09-29 |
Bayer Corp |
Peptidos que actuan como agonistas del receptor del glp-1 y como antagonistas del receptor del glucagon y sus metodos de uso farmacologico
|
US7041646B2
(en)
|
2001-10-05 |
2006-05-09 |
Bayer Pharmaceuticals Corporation |
Methods of treating type 2 diabetes with peptides acting as both GLP-1 receptor agonists and glucagon receptor antagonists
|
CA2471363C
(en)
|
2001-12-21 |
2014-02-11 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
MXPA04008068A
(es)
|
2002-02-20 |
2004-11-26 |
Lilly Co Eli |
Metodo para administrar moleculas de glp-1.
|
PL372316A1
(en)
|
2002-02-28 |
2005-07-11 |
Prosidion Limited |
Glutaminyl based dpiv inhibitors
|
ATE432289T1
(de)
|
2002-07-04 |
2009-06-15 |
Zealand Pharma As |
Glp-1 und behandlungsmethode für diabetes
|
WO2004022004A2
(en)
*
|
2002-09-06 |
2004-03-18 |
Bayer Pharmaceuticals Corporation |
Modified glp-1 receptor agonists and their pharmacological methods of use
|
CA2500021A1
(en)
|
2002-09-25 |
2004-04-08 |
Theratechnologies Inc. |
Modified glp-1 peptides with increased biological potency
|
US7273921B2
(en)
|
2002-09-25 |
2007-09-25 |
Novo Nordisk A/S |
Method for producing acylated peptides
|
US7411039B2
(en)
|
2002-10-14 |
2008-08-12 |
Novo Nordisk A/S |
GLP-2 compounds, formulations, and uses thereof
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
EP2256189A1
(en)
*
|
2003-03-28 |
2010-12-01 |
National Institute Of Agrobiological Sciences |
Process for producing a plant storage organ in which a GLP-1 derivative recombinant protein is highly produced.
|
DE602004026712D1
(de)
|
2003-05-05 |
2010-06-02 |
Probiodrug Ag |
Medizinische verwendung von hemmern von glutaminyl und glutamatcyclasen
|
JP4806628B2
(ja)
|
2003-05-05 |
2011-11-02 |
プロビオドルグ エージー |
グルタミニルシクラーゼ阻害剤
|
US7094800B2
(en)
|
2003-07-25 |
2006-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Cyanopyrrolidides, process for their preparation and their use as medicaments
|
US7008957B2
(en)
|
2003-07-25 |
2006-03-07 |
Sanofi-Aventis Deutschland Gmbh |
Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments
|
US7094794B2
(en)
|
2003-07-28 |
2006-08-22 |
Sanofi-Aventis Deutschland Gmbh |
Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
|
DE10335092B3
(de)
|
2003-08-01 |
2005-02-03 |
Aventis Pharma Deutschland Gmbh |
Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
|
WO2005019261A1
(en)
|
2003-08-21 |
2005-03-03 |
Novo Nordisk A/S |
Separation of polypeptides comprising a racemized amino acid
|
WO2005027978A2
(en)
|
2003-09-19 |
2005-03-31 |
Novo Nordisk A/S |
Albumin-binding derivatives of therapeutic peptides
|
MXPA06003998A
(es)
|
2003-10-15 |
2006-06-27 |
Probiodrug Ag |
Uso de efectores de ciclasas de glutamato y glutaminil.
|
KR101243648B1
(ko)
|
2003-11-20 |
2013-03-14 |
노보 노르디스크 에이/에스 |
제조 및 주사 장치용에 최적인 프로필렌 글리콜 함유펩티드 제제
|
EP2298337B1
(en)
|
2003-12-09 |
2017-02-22 |
Novo Nordisk A/S |
Regulation of food preference using GLP-1 agonists
|
EP1694278A4
(en)
|
2003-12-16 |
2009-08-12 |
Ipsen Pharma |
GLP-1 PHARMACEUTICAL COMPOSITIONS
|
EP1711523B1
(en)
|
2003-12-16 |
2012-10-10 |
Ipsen Pharma |
Analogues of glp-1
|
DE602004026113D1
(de)
|
2003-12-18 |
2010-04-29 |
Novo Nordisk As |
Glp-1-verbindungen
|
EP1709071A4
(en)
*
|
2004-01-08 |
2007-05-30 |
Theratechnologies Inc |
PEPTIDE ANALOGUES 1 LIKE LONG-ACTING GLUCAGON-LIKE
|
US8076288B2
(en)
|
2004-02-11 |
2011-12-13 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides having glucose lowering activity
|
AU2005211755B2
(en)
|
2004-02-11 |
2012-03-15 |
Amylin Pharmaceuticals, Llc |
Hybrid polypeptides with selectable properties
|
EP2316446A1
(en)
|
2004-06-11 |
2011-05-04 |
Novo Nordisk A/S |
Counteracting drug-induced obesity using GLP-1 agonists
|
KR20070039593A
(ko)
*
|
2004-07-21 |
2007-04-12 |
암브룩스, 인코포레이티드 |
비천연적으로 코딩된 아미노산을 이용한 생합성 폴리펩티드
|
US20090214534A1
(en)
|
2004-12-02 |
2009-08-27 |
Steve Holmes |
Bispecific Domain Antibodies Targeting Serum Albumin And GLP-1 Or PYY
|
AU2006213607A1
(en)
|
2005-02-11 |
2006-08-17 |
Amylin Pharmaceuticals, Llc |
GIP analog and hybrid polypeptides with selectable properties
|
US8263545B2
(en)
|
2005-02-11 |
2012-09-11 |
Amylin Pharmaceuticals, Inc. |
GIP analog and hybrid polypeptides with selectable properties
|
TWI372629B
(en)
|
2005-03-18 |
2012-09-21 |
Novo Nordisk As |
Acylated glp-1 compounds
|
WO2006097538A1
(en)
|
2005-03-18 |
2006-09-21 |
Novo Nordisk A/S |
Extended glp-1 compounds
|
US8946149B2
(en)
|
2005-04-11 |
2015-02-03 |
Amylin Pharmaceuticals, Llc |
Use of exendin and analogs thereof to delay or prevent cardiac remodeling
|
EP1889618A4
(en)
*
|
2005-05-27 |
2010-11-24 |
Daiichi Sankyo Co Ltd |
COMBINED MEDICINE FOR THE TREATMENT OF DIABETES
|
EP2330125A3
(en)
|
2005-08-11 |
2012-12-12 |
Amylin Pharmaceuticals, Inc. |
Hybrid polypeptides with selectable properties
|
AU2006279680B2
(en)
|
2005-08-11 |
2012-12-06 |
Amylin Pharmaceuticals, Llc |
Hybrid polypeptides with selectable properties
|
GT200600381A
(es)
|
2005-08-25 |
2007-03-28 |
|
Compuestos organicos
|
CN102935081B
(zh)
|
2005-09-14 |
2015-03-04 |
武田药品工业株式会社 |
用于治疗糖尿病的二肽基肽酶抑制剂
|
SI1942898T2
(sl)
|
2005-09-14 |
2014-08-29 |
Takeda Pharmaceutical Company Limited |
Dipeptidil-peptidazni inhibitorji za zdravljenje diabetesa
|
CN102675221A
(zh)
|
2005-09-16 |
2012-09-19 |
武田药品工业株式会社 |
用于制备嘧啶二酮衍生物的方法中的中间体
|
ES2397289T3
(es)
|
2005-09-22 |
2013-03-06 |
Biocompatibles Uk Ltd. |
Polipéptidos de fusión de GLP-1 (péptido 1 de tipo glucagón) con resistencia a peptidasa incrementada
|
EP1943275B1
(en)
*
|
2005-11-01 |
2010-06-16 |
Activotec SPP Limited |
Insulinotropic compounds and uses thereof
|
WO2007056362A2
(en)
|
2005-11-07 |
2007-05-18 |
Indiana University Research And Technology Corporation |
Glucagon analogs exhibiting physiological solubility and stability
|
CN100374462C
(zh)
*
|
2005-11-21 |
2008-03-12 |
大连帝恩生物工程有限公司 |
截短胰高血糖素样肽1(sGLP-1)、制法及其应用
|
EP1961764B1
(en)
*
|
2005-11-30 |
2011-05-11 |
Shionogi Co., Ltd. |
Sugar chain adduct of peptide and pharmaceutical comprising the same as active ingredient
|
US8293869B2
(en)
|
2005-12-16 |
2012-10-23 |
Nektar Therapeutics |
Polymer conjugates of GLP-1
|
MX2008013304A
(es)
|
2006-04-20 |
2008-10-27 |
Amgen Inc |
Compuestos de peptido 1 tipo glucagon.
|
AU2007247137A1
(en)
*
|
2006-05-02 |
2007-11-15 |
Actogenix N.V. |
Microbial intestinal delivery of obesity related peptides
|
US8497240B2
(en)
|
2006-08-17 |
2013-07-30 |
Amylin Pharmaceuticals, Llc |
DPP-IV resistant GIP hybrid polypeptides with selectable properties
|
TW200838536A
(en)
|
2006-11-29 |
2008-10-01 |
Takeda Pharmaceutical |
Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
|
EP2111414B1
(en)
|
2007-02-15 |
2014-07-02 |
Indiana University Research and Technology Corporation |
Glucagon/glp-1 receptor co-agonists
|
CN101842386A
(zh)
|
2007-09-05 |
2010-09-22 |
诺沃-诺迪斯克有限公司 |
截短的glp-1衍生物和它们的治疗用途
|
WO2009030738A1
(en)
|
2007-09-05 |
2009-03-12 |
Novo Nordisk A/S |
Glucagon-like peptide-1 derivatives and their pharmaceutical use
|
WO2009058734A1
(en)
|
2007-10-30 |
2009-05-07 |
Indiana University Research And Technology Corporation |
Compounds exhibiting glucagon antagonist and glp-1 agonist activity
|
WO2009099763A1
(en)
|
2008-01-30 |
2009-08-13 |
Indiana University Research And Technology Corporation |
Ester-based peptide prodrugs
|
CA2718480A1
(en)
|
2008-03-31 |
2009-10-08 |
Glaxo Group Limited |
Drug fusions and conjugates
|
EA019203B9
(ru)
|
2008-06-17 |
2014-03-31 |
Индиана Юниверсити Рисерч Энд Текнолоджи Корпорейшн |
Коагонисты глюкагонового рецептора/glp-1-рецептора
|
US9062124B2
(en)
|
2008-06-17 |
2015-06-23 |
Indiana University Research And Technology Corporation |
GIP-based mixed agonists for treatment of metabolic disorders and obesity
|
AU2009279090A1
(en)
|
2008-08-06 |
2010-02-11 |
Novo Nordisk Health Care Ag |
Conjugated proteins with prolonged in vivo efficacy
|
ES2614427T3
(es)
|
2008-11-07 |
2017-05-31 |
The General Hospital Corporation |
Fragmentos C-terminales de péptido glucagonoide 1 (GLP-1)
|
US9441028B2
(en)
|
2008-12-08 |
2016-09-13 |
Novo Nordisk A/S |
Counter current purification of polypeptides
|
HUE031900T2
(en)
*
|
2008-12-10 |
2017-08-28 |
Glaxosmithkline Llc |
Pharmaceutical compositions containing Albiglutide
|
TWI489992B
(zh)
|
2008-12-19 |
2015-07-01 |
印地安那大學研究及技術公司 |
醯胺系胰高血糖素超級家族之胜肽前驅藥物
|
JP5816097B2
(ja)
|
2009-01-22 |
2015-11-18 |
ノヴォ・ノルディスク・ヘルス・ケア・アーゲー |
安定な成長ホルモン化合物
|
CN104127880A
(zh)
|
2009-03-27 |
2014-11-05 |
葛兰素集团有限公司 |
药用融合体和缀合物
|
BRPI1012852A2
(pt)
|
2009-05-15 |
2018-06-19 |
Novartis Ag |
derivados de benzoxazolona como inibidores da sintase de aldoesterona
|
CN104892502B
(zh)
|
2009-05-15 |
2017-08-04 |
诺华股份有限公司 |
作为醛固酮合酶抑制剂的芳基吡啶
|
KR101442897B1
(ko)
|
2009-05-28 |
2014-09-23 |
노파르티스 아게 |
네프릴리신 억제제로서의 치환된 아미노프로피온산 유도체
|
CN102448928B
(zh)
|
2009-05-28 |
2014-10-01 |
诺华股份有限公司 |
作为中性溶酶(neprilysin)抑制剂的取代的氨基丁酸衍生物
|
MX2011013625A
(es)
|
2009-06-16 |
2012-01-20 |
Univ Indiana Res & Tech Corp |
Compuestos glucagon activo de receptor de gip.
|
US8841249B2
(en)
|
2009-08-06 |
2014-09-23 |
Novo Nordisk A/S |
Growth hormones with prolonged in-vivo efficacy
|
US20120276098A1
(en)
|
2009-09-30 |
2012-11-01 |
Bruce Hamilton |
Drug fusions and conjugates with extended half life
|
WO2011041293A1
(en)
|
2009-09-30 |
2011-04-07 |
Takeda Pharmaceutical Company Limited |
Pyrazolo [1, 5-a] pyrimidine derivatives as apoptosis signal-regulating kinase 1 inhibitors
|
CN102712589B
(zh)
|
2009-11-17 |
2015-05-13 |
诺华股份有限公司 |
作为醛固酮合酶抑制剂的芳基-吡啶衍生物
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
JP5575913B2
(ja)
|
2009-11-30 |
2014-08-20 |
ノバルティス アーゲー |
アルドステロン合成酵素阻害剤としてのイミダゾール誘導体
|
WO2011080102A2
(en)
*
|
2009-12-16 |
2011-07-07 |
Novo Nordisk A/S |
Glp-1 analogues and derivatives
|
AU2011208625C1
(en)
|
2010-01-22 |
2022-08-18 |
Novo Nordisk Health Care Ag |
Growth hormones with prolonged in-vivo efficacy
|
AU2011208620B2
(en)
|
2010-01-22 |
2015-04-16 |
Novo Nordisk Health Care Ag |
Stable growth hormone compounds
|
MX2012008603A
(es)
|
2010-01-27 |
2013-01-25 |
Univ Indiana Res & Tech Corp |
Conjugados de antagonista de glucagon-agonista de gip y composiciones para el tratamiento de desordenes metabolicos y obesidad.
|
ES2445917T3
(es)
|
2010-02-03 |
2014-03-06 |
Takeda Pharmaceutical Company Limited |
Inhibidores de quinasa 1 reguladora de la señal de apoptosis
|
EP2555791B1
(en)
|
2010-04-09 |
2017-11-01 |
Sinai Health System |
Methods for treating disorders of the gastrointestinal tract using a glp-1 agonist
|
WO2011133948A2
(en)
|
2010-04-22 |
2011-10-27 |
Longevity Biotech, Inc. |
Highly active polypeptides and methods of making and using the same
|
JP5969461B2
(ja)
|
2010-04-27 |
2016-08-17 |
ジーランド ファーマ アクティーゼルスカブ |
Glp−1受容体作動薬とガストリンとのペプチド複合体及びその使用
|
AU2011245980A1
(en)
|
2010-04-30 |
2012-11-08 |
Sanwa Kagaku Kenkyusho Co., Ltd. |
Peptide for improving in vivo stability of physiologically active substance or the like and physiologically active substance with improved in vivo stability
|
BR112012029248B1
(pt)
|
2010-05-17 |
2021-09-28 |
Betta Pharmaceuticals Co., Ltd |
Análogo de glp-1 de fórmula i ou a sua composição, análogo de glp-1 de fórmula viii ou um sal farmaceuticamente aceitável ou a composição do mesmo, composição farmacêutica e uso de um composto
|
JP5912112B2
(ja)
|
2010-06-24 |
2016-04-27 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
アミド系インスリンプロドラッグ
|
WO2011163012A2
(en)
|
2010-06-24 |
2011-12-29 |
Indiana University Research And Technology Corporation |
Amide based glucagon superfamily peptide prodrugs
|
WO2012054861A1
(en)
|
2010-10-22 |
2012-04-26 |
Nektar Therapeutics |
Glp-1 polymer conjugates having a releasable linkage
|
WO2012054822A1
(en)
|
2010-10-22 |
2012-04-26 |
Nektar Therapeutics |
Pharmacologically active polymer-glp-1 conjugates
|
WO2012061466A2
(en)
|
2010-11-02 |
2012-05-10 |
The General Hospital Corporation |
Methods for treating steatotic disease
|
US8877815B2
(en)
|
2010-11-16 |
2014-11-04 |
Novartis Ag |
Substituted carbamoylcycloalkyl acetic acid derivatives as NEP
|
US8673974B2
(en)
|
2010-11-16 |
2014-03-18 |
Novartis Ag |
Substituted amino bisphenyl pentanoic acid derivatives as NEP inhibitors
|
HUE036066T2
(hu)
|
2010-12-16 |
2018-06-28 |
Novo Nordisk As |
GLP-1 agonistát és N-(8-(2-hidroxibenzoil)amino)kaprilsav sóját tartalmazó szilárd készítmények
|
PE20140186A1
(es)
|
2010-12-22 |
2014-02-13 |
Univ Indiana Res & Tech Corp |
Analogos de glucagon que presentan actividad de receptor de gip
|
CA2828147A1
(en)
|
2011-03-08 |
2012-09-13 |
Sanwa Kagaku Kenkyusho Co., Ltd. |
Analysis method
|
WO2012136790A1
(en)
|
2011-04-07 |
2012-10-11 |
Glaxo Group Limited |
Compositions comprising fusion proteins or conjugates with an improved half -life
|
WO2012136792A2
(en)
|
2011-04-07 |
2012-10-11 |
Glaxo Group Limited |
Cck compositions
|
PT2696687T
(pt)
|
2011-04-12 |
2017-02-02 |
Novo Nordisk As |
Derivados de glp-1 duplamente acilados
|
MX2013015168A
(es)
|
2011-06-22 |
2014-03-31 |
Univ Indiana Res & Tech Corp |
Co-agonista del receptor de glucagon/glp-1.
|
GEP20176629B
(en)
|
2011-06-22 |
2017-02-27 |
Indiana Unversity Research And Tech Corporation |
Glucagon/glp-1 receptor co-agonists
|
US9944687B2
(en)
|
2011-07-04 |
2018-04-17 |
Imperial Innovations Limited |
Compounds and their effects on feeding behaviour
|
EP2729157B1
(en)
|
2011-07-06 |
2019-01-16 |
The General Hospital Corporation |
A pentapeptide derived from the c-terminus of glucagon-like peptide 1 (glp-1) for use in treatment
|
EP2771025A1
(en)
*
|
2011-10-28 |
2014-09-03 |
Pharis Biotec GmbH |
A polypeptide for the protection against heart ischemia-reperfusion injury
|
MX2014005351A
(es)
|
2011-11-03 |
2014-05-28 |
Zealand Pharma As |
Conjugados de gastrina peptidicos de agonistas de receptor glp-1.
|
WO2013083826A2
(en)
*
|
2011-12-09 |
2013-06-13 |
Novo Nordisk A/S |
Glp-1 agonists
|
DK2827845T3
(da)
|
2012-03-22 |
2019-04-01 |
Novo Nordisk As |
Sammensætninger omfattende et fremføringsmiddel og fremstilling deraf
|
RU2641198C3
(ru)
|
2012-03-22 |
2021-12-10 |
Ново Нордиск А/С |
Композиции glp-1 пептидов и их получение
|
US20150342897A1
(en)
|
2012-05-16 |
2015-12-03 |
Glaxo Group Limited |
Polypeptide loaded poca nanoparticles for oral administration
|
EP2863895B1
(en)
|
2012-06-20 |
2021-04-14 |
Novo Nordisk A/S |
Tablet formulation comprising a peptide and a delivery agent
|
JP6311708B2
(ja)
|
2012-06-21 |
2018-04-18 |
インディアナ ユニバーシティー リサーチ アンド テクノロジー コーポレーションIndiana University Research And Technology Corporation |
Gip受容体活性を示すグルカゴンアナローグ
|
EP2873422A4
(en)
|
2012-07-10 |
2015-12-30 |
Takeda Pharmaceutical |
PHARMACEUTICAL PREPARATION FOR INJECTION
|
CA2878991C
(en)
|
2012-07-23 |
2021-12-07 |
Zealand Pharma A/S |
Glucagon analogues
|
TWI608013B
(zh)
|
2012-09-17 |
2017-12-11 |
西蘭製藥公司 |
升糖素類似物
|
UY35144A
(es)
|
2012-11-20 |
2014-06-30 |
Novartis Ag |
Miméticos lineales sintéticos de apelina para el tratamiento de insuficiencia cardiaca
|
DK2956464T3
(da)
|
2013-02-14 |
2018-07-16 |
Novartis Ag |
Substituerede bisphenyl-butan-phosphonsyrederivater som NEP (neutral endopeptidase)-inhibitorer
|
US9789164B2
(en)
|
2013-03-15 |
2017-10-17 |
Longevity Biotech, Inc. |
Peptides comprising non-natural amino acids and methods of making and using the same
|
CN105120887A
(zh)
|
2013-04-05 |
2015-12-02 |
诺和诺德保健股份有限公司 |
生长激素化合物制剂
|
CA2909045C
(en)
|
2013-05-02 |
2022-12-06 |
Glaxosmithkline Intellectual Property Development Limited |
Therapeutic peptides
|
EP3024492A2
(en)
|
2013-07-25 |
2016-06-01 |
Novartis AG |
Bioconjugates of synthetic apelin polypeptides
|
PE20160878A1
(es)
|
2013-07-25 |
2016-09-08 |
Novartis Ag |
Polipeptidos ciclicos para el tratamiento de la insuficiencia cardiaca
|
US9988429B2
(en)
|
2013-10-17 |
2018-06-05 |
Zealand Pharma A/S |
Glucagon analogues
|
AR098065A1
(es)
|
2013-10-17 |
2016-04-27 |
Zealand Pharma As |
Análogos de glucagón acilados
|
WO2015067715A2
(en)
|
2013-11-06 |
2015-05-14 |
Zealand Pharma A/S |
Gip-glp-1 dual agonist compounds and methods
|
EA035688B1
(ru)
|
2013-11-06 |
2020-07-27 |
Зилэнд Фарма А/С |
Соединения, которые представляют собой тройные агонисты глюкагона, glp-1 и gip
|
EP3985016A1
(en)
|
2014-10-29 |
2022-04-20 |
Zealand Pharma A/S |
Gip agonist compounds and methods
|
CU20170093A7
(es)
|
2015-01-23 |
2017-09-06 |
Novartis Ag |
Conjugados de ácidos grasos y apelina sintética con mayor vida media
|
KR20170137198A
(ko)
|
2015-04-16 |
2017-12-12 |
질랜드 파마 에이/에스 |
아실화된 글루카곤 유사체
|
EP3463424A1
(en)
*
|
2016-06-02 |
2019-04-10 |
Indiana University Research & Technology Corporation |
Glucagon-like peptide-1-t3 conjugates
|
JOP20190086A1
(ar)
|
2016-10-21 |
2019-04-18 |
Novartis Ag |
مشتقات نافثيريدينون جديدة واستخدامها في معالجة عدم انتظام ضربات القلب
|
SG11201903938XA
(en)
|
2016-12-09 |
2019-05-30 |
Zealand Pharma As |
Acylated glp-1/glp-2 dual agonists
|
CN111050750A
(zh)
|
2017-08-24 |
2020-04-21 |
诺沃挪第克公司 |
Glp-1组合物及其用途
|
CN115109166A
(zh)
*
|
2017-11-24 |
2022-09-27 |
浙江道尔生物科技有限公司 |
一种治疗代谢疾病的多结构域活性蛋白
|
PE20210453A1
(es)
|
2018-02-02 |
2021-03-08 |
Novo Nordisk As |
Composiciones solidas que comprenden un agonista de glp-1, una sal del acido n-(8-(2-hidroxibenzoil)amino)caprilico y un lubricante
|
UY38072A
(es)
|
2018-02-07 |
2019-10-01 |
Novartis Ag |
Compuestos derivados de éster butanoico sustituido con bisfenilo como inhibidores de nep, composiciones y combinaciones de los mismos
|
UY38485A
(es)
|
2018-11-27 |
2020-06-30 |
Novartis Ag |
Compuestos tetrámeros cíclicos como inhibidores de proproteína convertasa subtilisina/kexina tipo 9 (pcsk9), método de tratamiento, uso y su preparación
|
JP2022509184A
(ja)
|
2018-11-27 |
2022-01-20 |
ノバルティス アーゲー |
代謝性障害の処置のためのプロタンパク質コンバターゼスブチリシン/ケキシン9型(pcsk9)阻害剤としての環状ペプチド
|
EP3887363A1
(en)
|
2018-11-27 |
2021-10-06 |
Novartis AG |
Cyclic pentamer compounds as proprotein convertase subtilisin/kexin type 9 (pcsk9) inhibitors for the treatment of metabolic disorder
|
GB201917723D0
(en)
|
2019-12-04 |
2020-01-15 |
Nv Rose Llc |
Stable liquid formulations of glucagon-like peptide 1 or analogues thereof
|
MX2022009523A
(es)
|
2020-02-18 |
2022-09-09 |
Novo Nordisk As |
Formulaciones farmaceuticas.
|
CA3193453A1
(en)
|
2020-09-30 |
2022-04-07 |
Beijing Ql Biopharmaceutical Co., Ltd. |
Polypeptide conjugates and methods of uses
|
TW202333563A
(zh)
|
2021-11-12 |
2023-09-01 |
瑞士商諾華公司 |
用於治療疾病或障礙之二胺基環戊基吡啶衍生物
|
AR127698A1
(es)
|
2021-11-23 |
2024-02-21 |
Novartis Ag |
Derivados de naftiridinona para el tratamiento de una enfermedad o un trastorno
|
CN114716533B
(zh)
*
|
2022-04-12 |
2023-04-14 |
北京惠之衡生物科技有限公司 |
一种酰化的长效glp-1衍生物
|
WO2024106505A1
(ja)
*
|
2022-11-16 |
2024-05-23 |
株式会社ポル・メド・テック |
豚臓器又はその由来物を含む移植材の製造方法
|