NO317662B1 - Formerings- og respiratorisk syndromvirusisolat fra gris, fremgangsmate for a dyrke isolatet og anvendelse derav i vaksiner - Google Patents
Formerings- og respiratorisk syndromvirusisolat fra gris, fremgangsmate for a dyrke isolatet og anvendelse derav i vaksiner Download PDFInfo
- Publication number
- NO317662B1 NO317662B1 NO19953091A NO953091A NO317662B1 NO 317662 B1 NO317662 B1 NO 317662B1 NO 19953091 A NO19953091 A NO 19953091A NO 953091 A NO953091 A NO 953091A NO 317662 B1 NO317662 B1 NO 317662B1
- Authority
- NO
- Norway
- Prior art keywords
- prrsv
- virus
- isolate
- vaccine
- tissue culture
- Prior art date
Links
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- 241000700605 Viruses Species 0.000 title claims description 57
- 229960005486 vaccine Drugs 0.000 title claims description 36
- 208000011580 syndromic disease Diseases 0.000 title claims description 14
- 230000000241 respiratory effect Effects 0.000 title claims description 8
- 230000001850 reproductive effect Effects 0.000 title description 8
- 208000005342 Porcine Reproductive and Respiratory Syndrome Diseases 0.000 claims abstract description 28
- 208000015181 infectious disease Diseases 0.000 claims abstract description 11
- 230000010076 replication Effects 0.000 claims abstract description 6
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- 239000007788 liquid Substances 0.000 claims 1
- 229960000380 propiolactone Drugs 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
- 241001135989 Porcine reproductive and respiratory syndrome virus Species 0.000 abstract description 55
- 201000010099 disease Diseases 0.000 description 17
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 17
- 210000001519 tissue Anatomy 0.000 description 15
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- WJAXXWSZNSFVNG-UHFFFAOYSA-N 2-bromoethanamine;hydron;bromide Chemical compound [Br-].[NH3+]CCBr WJAXXWSZNSFVNG-UHFFFAOYSA-N 0.000 description 1
- 241000867607 Chlorocebus sabaeus Species 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 1
- 206010055690 Foetal death Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
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- 239000003242 anti bacterial agent Substances 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 229940031567 attenuated vaccine Drugs 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5252—Virus inactivated (killed)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
- C12N2770/00011—Details
- C12N2770/10011—Arteriviridae
- C12N2770/10034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S424/00—Drug, bio-affecting and body treating compositions
- Y10S424/815—Viral vaccine for porcine species, e.g. swine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1491593A | 1993-02-08 | 1993-02-08 | |
| PCT/US1994/000951 WO1994018311A1 (en) | 1993-02-08 | 1994-01-26 | Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO953091L NO953091L (no) | 1995-08-07 |
| NO953091D0 NO953091D0 (no) | 1995-08-07 |
| NO317662B1 true NO317662B1 (no) | 2004-11-29 |
Family
ID=21768529
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO19953091A NO317662B1 (no) | 1993-02-08 | 1995-08-07 | Formerings- og respiratorisk syndromvirusisolat fra gris, fremgangsmate for a dyrke isolatet og anvendelse derav i vaksiner |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US5510258A (hu) |
| EP (1) | EP0683816B1 (hu) |
| JP (1) | JP3710095B2 (hu) |
| KR (1) | KR100374295B1 (hu) |
| CN (1) | CN1080300C (hu) |
| AT (1) | ATE197314T1 (hu) |
| AU (1) | AU681874B2 (hu) |
| BG (1) | BG63170B1 (hu) |
| CZ (1) | CZ289743B6 (hu) |
| DE (1) | DE69426228T2 (hu) |
| DK (1) | DK0683816T3 (hu) |
| ES (1) | ES2152304T3 (hu) |
| FI (1) | FI117513B (hu) |
| GR (1) | GR3035257T3 (hu) |
| HU (1) | HU218430B (hu) |
| NO (1) | NO317662B1 (hu) |
| NZ (1) | NZ261992A (hu) |
| PL (1) | PL178609B1 (hu) |
| PT (1) | PT683816E (hu) |
| SK (1) | SK98695A3 (hu) |
| WO (1) | WO1994018311A1 (hu) |
Families Citing this family (60)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2103460C (en) | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
| US5846805A (en) | 1991-08-26 | 1998-12-08 | Boehringer Ingelheim Animal Health, Inc. | Culture of swine infertility and respiratory syndrome virus in simian cells |
| US6042830A (en) * | 1992-08-05 | 2000-03-28 | Boehringer Ingelheim Vetmedica, Inc. | Viral agent associated with mystery swine disease |
| US6982160B2 (en) * | 1991-08-26 | 2006-01-03 | Boehringer Ingelheim Vetmedica, Inc. | Immunogenic compositions that include SIRS virus |
| US6080570A (en) * | 1991-08-26 | 2000-06-27 | Boehringer Ingelheim Vetmedica, Inc. | Method of producing a vaccine for Swine Infertility and Respiratory Syndrome |
| US6773908B1 (en) * | 1992-10-30 | 2004-08-10 | Iowa State University Research Foundation, Inc. | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US6380376B1 (en) | 1992-10-30 | 2002-04-30 | Iowa State University Research Foundation | Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV) |
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
| US6592873B1 (en) | 1992-10-30 | 2003-07-15 | Iowa State University Research Foundation, Inc. | Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids |
| ES2074950B1 (es) * | 1993-09-17 | 1996-03-16 | Iberica Cyanamid | Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda. |
| US5690940A (en) * | 1995-06-21 | 1997-11-25 | Regents Of The University Of Minnesota | Low pathogencity PRRS live virus vaccines and methods of preparation thereof |
| ES2102971B1 (es) * | 1996-01-25 | 1998-03-01 | Hipra Lab Sa | Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion. |
| AU2277497A (en) * | 1996-03-01 | 1997-09-16 | Schering Corporation | Porcine reproductive and respiratory syndrome vaccine |
| US6015663A (en) * | 1996-03-01 | 2000-01-18 | The United States Of America As Represented By The Secretary Of Agriculture | Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains |
| US5866401A (en) * | 1996-03-01 | 1999-02-02 | Schering Corporation | Porcine reproductive and respiratory syndrome vaccine |
| US5976537A (en) * | 1996-07-02 | 1999-11-02 | The United States Of America As Represented By The Secretary Of Agriculture | Porcine reproductive and respiratory syndrome vaccine |
| EP0835930B1 (en) * | 1996-10-09 | 2001-01-31 | Akzo Nobel N.V. | European vaccine strains of the porcine reproductive and respiratory syndrome virus (PRRSV) |
| EP0839912A1 (en) | 1996-10-30 | 1998-05-06 | Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| US20040224327A1 (en) * | 1996-10-30 | 2004-11-11 | Meulenberg Johanna Jacoba Maria | Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof |
| WO1998035023A1 (en) * | 1997-02-07 | 1998-08-13 | Origen, Inc. | Method for growing porcine reproductive and respiratory syndrome virus for use as vaccines and diagnostic assays |
| PT980387E (pt) | 1997-05-06 | 2007-07-31 | Boehringer Ingelheim Vetmed | Sítios antigénicos de prrsv que identificam sequências peptídicas do vírus prrsv para utilização em vacinas ou em ensaios de diagnóstico |
| WO1999002184A1 (en) * | 1997-07-10 | 1999-01-21 | Regents Of The University Of Minnesota | Causative agent of sow abortion and mortality syndrome (sams), vaccine compositions, antibodies and method |
| UA78180C2 (uk) | 1997-10-03 | 2007-03-15 | Меріаль | Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти |
| FR2772047B1 (fr) | 1997-12-05 | 2004-04-09 | Ct Nat D Etudes Veterinaires E | Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection |
| CA2440933A1 (en) | 1998-12-22 | 2000-06-22 | Pfizer Products Inc. | An infectious cdna clone of north american porcine reproductive and respiratory syndrome (prrs) virus and uses thereof |
| CA2366072C (en) | 1999-03-08 | 2007-07-10 | Id-Lelystad, Instituut Voor Dierhouderij En Diergezondheid B.V. | Prrsv vaccines |
| CA2370372C (en) * | 1999-04-22 | 2009-02-24 | United States Department Of Agriculture | Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142 |
| US6497883B1 (en) * | 1999-06-10 | 2002-12-24 | Merial | Porcine circovirus recombinant poxvirus vaccine |
| ES2170622B1 (es) * | 1999-12-03 | 2004-05-16 | Consejo Superior De Investigaciones Cientificas | Clones y vectores infectivos derivados de coronavirus y sus aplicaciones. |
| ES2300286T3 (es) * | 1999-12-20 | 2008-06-16 | Agricultural Research Council | Procedimiento de inactivacion de microorganismos. |
| EP1255815B1 (en) * | 2000-02-08 | 2006-07-19 | Regents Of The University Of Minnesota | Porcine reproductive and respiratory syndrome virus and methods of use |
| US6740490B2 (en) * | 2001-01-29 | 2004-05-25 | Kansas State University Research Foundation | Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding |
| US6841364B2 (en) * | 2002-01-22 | 2005-01-11 | Protatek International, Inc. | Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof |
| US7906311B2 (en) | 2002-03-20 | 2011-03-15 | Merial Limited | Cotton rat lung cells for virus culture |
| JP2008503727A (ja) | 2004-06-18 | 2008-02-07 | リージェンツ オブ ザ ユニバーシティ オブ ミネソタ | ウイルス感染した生物およびワクチン接種した生物の同定 |
| US7632636B2 (en) | 2004-09-21 | 2009-12-15 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome isolates and methods of use |
| ES2532861T3 (es) | 2004-12-30 | 2015-04-01 | Boehringer Ingelheim Vetmedica, Inc. | Composiciones inmunogénicas para PCV2 para uso en un método de prevenir una infección por PCV2 |
| US7691368B2 (en) | 2005-04-15 | 2010-04-06 | Merial Limited | Vaccine formulations |
| MX2007015849A (es) | 2005-06-24 | 2008-02-22 | Univ Minnesota | Virus del sindrome respiratorio y reproductivo porcino, clones infecciosos, mutantes de los mismos, y metodos de uso. |
| EP1968630B1 (en) | 2005-12-29 | 2018-01-24 | Boehringer Ingelheim Vetmedica, Inc. | Multivalent pcv2 immunogenic compositions |
| CN100523177C (zh) * | 2007-01-09 | 2009-08-05 | 中国农业科学院哈尔滨兽医研究所 | 猪繁殖与呼吸综合症病毒弱毒疫苗株及其应用 |
| WO2008089094A2 (en) * | 2007-01-12 | 2008-07-24 | The Board Of Trustees Of The University Of Illinois | Non-simian cells for growth of porcine reproductive and respiratory syndrome (prrs) virus |
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| CN101848995A (zh) * | 2007-06-25 | 2010-09-29 | 南达科他州立大学 | 重组的北美1型猪繁殖与呼吸综合征病毒及使用方法 |
| FI122778B (fi) | 2008-03-31 | 2012-06-29 | Metso Power Oy | Pyrolyysimenetelmä kattilan yhteydessä ja pyrolyysilaitteisto |
| CN101363865B (zh) * | 2008-05-26 | 2013-03-06 | 北京庄笛浩禾生物医学科技有限公司 | 一种猪蓝耳病毒胶体金检测试纸条、其制备方法及其应用 |
| WO2010025109A1 (en) * | 2008-08-25 | 2010-03-04 | Boehringer Ingelheim Vetmedia, Inc. | Vaccine against highly pathogenic porcine reproductive and respiratory syndrome (hp prrs) |
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| CA2827337C (en) | 2011-02-17 | 2019-07-09 | Boehringer Ingelheim Vetmedica Gmbh | Commercial scale process for production of prrsv |
| HUE027731T2 (hu) | 2011-02-17 | 2016-10-28 | Boehringer Ingelheim Vetmedica Gmbh | Új európai PRRSV-törzs |
| WO2013017568A1 (en) | 2011-07-29 | 2013-02-07 | Boehringer Ingelheim Vetmedica Gmbh | INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF |
| US9187731B2 (en) | 2011-07-29 | 2015-11-17 | Boehringer Ingelheim Vetmedica Gmbh | PRRS virus inducing type I interferon in susceptible cells |
| SI2741740T1 (sl) | 2011-08-12 | 2017-08-31 | Merial, Inc. | Vakuumsko konzerviranje bioloških proizvodov, zlasti cepiv |
| WO2014089117A1 (en) | 2012-12-07 | 2014-06-12 | The Board Of Trustees Of The University Of Illinois | Porcine reproductive and respiratory syndrome virus compositions and uses thereof |
| EP2968513A2 (en) | 2013-03-15 | 2016-01-20 | Boehringer Ingelheim Vetmedica, Inc. | Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use |
| CA2925281C (en) | 2013-09-25 | 2022-05-03 | Zoetis Services Llc | Pcv2b divergent vaccine composition and methods of use |
| TWI745278B (zh) | 2014-10-10 | 2021-11-11 | 以色列商艾畢克生物實驗有限公司 | 發泡性降低之疫苗組合物 |
| CN104694485A (zh) * | 2015-02-13 | 2015-06-10 | 广西壮族自治区兽医研究所 | Z-ietd-fmk在提高prrsv体外培养滴度方面的应用及其方法 |
| KR20190044052A (ko) | 2016-06-17 | 2019-04-29 | 메리얼 인코포레이티드 | 선형 또는 분지형 폴리아크릴산 폴리머 아쥬반트를 포함하는 신규한 면역원성 제형 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5213795A (en) * | 1990-10-24 | 1993-05-25 | Oxford | Encephalomyocarditis virus vaccine |
| CA2103460C (en) * | 1991-06-06 | 2000-09-26 | Gert Wensvoort | Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits |
| DK0601062T4 (da) * | 1991-08-26 | 2001-03-14 | Univ Minnesota | SIRS-vaccine og diagnosefremgangsmåde |
| CA2076744C (en) * | 1991-08-26 | 2000-06-27 | Danny W. Chladek | Viral agent associated with mystery swine disease |
| AU2696792A (en) * | 1991-09-16 | 1993-04-27 | David A Benfield | Vaccine for mystery swine disease and method for diagnosis thereof |
| ES2083764T5 (es) * | 1991-10-14 | 2009-04-01 | Intervet International Bv | Vacuna para el sindrome respiratorio reproductivo porcino (srrp) y diagnostico. |
| FR2682966B1 (fr) * | 1991-10-29 | 1994-12-02 | Rhone Merieux | Preparation d'antigenes et de vaccins du virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie. |
| US5695766A (en) * | 1992-10-30 | 1997-12-09 | Iowa State University Research Foundation | Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome |
-
1994
- 1994-01-26 SK SK986-95A patent/SK98695A3/sk unknown
- 1994-01-26 AT AT94907895T patent/ATE197314T1/de not_active IP Right Cessation
- 1994-01-26 JP JP51810194A patent/JP3710095B2/ja not_active Expired - Fee Related
- 1994-01-26 DK DK94907895T patent/DK0683816T3/da active
- 1994-01-26 HU HU9502330A patent/HU218430B/hu not_active IP Right Cessation
- 1994-01-26 KR KR1019950703246A patent/KR100374295B1/ko not_active IP Right Cessation
- 1994-01-26 PT PT94907895T patent/PT683816E/pt unknown
- 1994-01-26 PL PL94310126A patent/PL178609B1/pl not_active IP Right Cessation
- 1994-01-26 EP EP94907895A patent/EP0683816B1/en not_active Expired - Lifetime
- 1994-01-26 DE DE69426228T patent/DE69426228T2/de not_active Expired - Fee Related
- 1994-01-26 AU AU61285/94A patent/AU681874B2/en not_active Ceased
- 1994-01-26 CN CN94191129A patent/CN1080300C/zh not_active Expired - Fee Related
- 1994-01-26 ES ES94907895T patent/ES2152304T3/es not_active Expired - Lifetime
- 1994-01-26 WO PCT/US1994/000951 patent/WO1994018311A1/en active IP Right Grant
- 1994-01-26 CZ CZ19952031A patent/CZ289743B6/cs not_active IP Right Cessation
- 1994-01-26 NZ NZ261992A patent/NZ261992A/en not_active IP Right Cessation
- 1994-06-01 US US08/252,612 patent/US5510258A/en not_active Expired - Lifetime
- 1994-12-06 US US08/349,865 patent/US5587164A/en not_active Expired - Lifetime
-
1995
- 1995-08-04 FI FI953731A patent/FI117513B/fi active IP Right Grant
- 1995-08-07 NO NO19953091A patent/NO317662B1/no unknown
- 1995-08-08 BG BG99850A patent/BG63170B1/bg unknown
-
2001
- 2001-01-17 GR GR20010400077T patent/GR3035257T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BG99850A (bg) | 1996-02-28 |
| NO953091L (no) | 1995-08-07 |
| NO953091D0 (no) | 1995-08-07 |
| CZ203195A3 (en) | 1995-12-13 |
| CN1080300C (zh) | 2002-03-06 |
| US5510258A (en) | 1996-04-23 |
| EP0683816B1 (en) | 2000-11-02 |
| DE69426228D1 (de) | 2000-12-07 |
| FI953731A (fi) | 1995-08-04 |
| KR100374295B1 (ko) | 2003-12-24 |
| BG63170B1 (bg) | 2001-05-31 |
| FI117513B (fi) | 2006-11-15 |
| CN1117742A (zh) | 1996-02-28 |
| PL178609B1 (pl) | 2000-05-31 |
| FI953731A0 (fi) | 1995-08-04 |
| JPH08506486A (ja) | 1996-07-16 |
| NZ261992A (en) | 1996-06-25 |
| HU218430B (hu) | 2000-08-28 |
| HU9502330D0 (en) | 1996-05-28 |
| PL310126A1 (en) | 1995-11-27 |
| GR3035257T3 (en) | 2001-04-30 |
| PT683816E (pt) | 2001-03-30 |
| DE69426228T2 (de) | 2001-03-01 |
| AU6128594A (en) | 1994-08-29 |
| HUT72917A (en) | 1996-06-28 |
| AU681874B2 (en) | 1997-09-11 |
| JP3710095B2 (ja) | 2005-10-26 |
| WO1994018311A1 (en) | 1994-08-18 |
| ATE197314T1 (de) | 2000-11-15 |
| ES2152304T3 (es) | 2001-02-01 |
| SK98695A3 (en) | 1996-11-06 |
| US5587164A (en) | 1996-12-24 |
| EP0683816A1 (en) | 1995-11-29 |
| DK0683816T3 (da) | 2001-01-08 |
| CZ289743B6 (cs) | 2002-03-13 |
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