FI117513B - Menetelmä PRRS-viruksen viljelemiseksi ja sen käyttö rokotteissa - Google Patents

Menetelmä PRRS-viruksen viljelemiseksi ja sen käyttö rokotteissa Download PDF

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Publication number
FI117513B
FI117513B FI953731A FI953731A FI117513B FI 117513 B FI117513 B FI 117513B FI 953731 A FI953731 A FI 953731A FI 953731 A FI953731 A FI 953731A FI 117513 B FI117513 B FI 117513B
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FI
Finland
Prior art keywords
prrsv
virus
prrs
tissue culture
cell line
Prior art date
Application number
FI953731A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI953731A (fi
FI953731A0 (fi
Inventor
Thomas Sanderson
Michael J Mcginley
Jeffrey J Zimmerman
Howard T Hill
Michael C Meetz
Eugene C Pirtle
Sabrina L Swenson
George P Shibley
Original Assignee
Univ Iowa State Res Found Inc
Bayer Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Iowa State Res Found Inc, Bayer Corp filed Critical Univ Iowa State Res Found Inc
Publication of FI953731A publication Critical patent/FI953731A/fi
Publication of FI953731A0 publication Critical patent/FI953731A0/fi
Application granted granted Critical
Publication of FI117513B publication Critical patent/FI117513B/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/12Viral antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5252Virus inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525Virus
    • A61K2039/5254Virus avirulent or attenuated
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55566Emulsions, e.g. Freund's adjuvant, MF59
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011Details
    • C12N2770/10011Arteriviridae
    • C12N2770/10034Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/815Viral vaccine for porcine species, e.g. swine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
FI953731A 1993-02-08 1995-08-04 Menetelmä PRRS-viruksen viljelemiseksi ja sen käyttö rokotteissa FI117513B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US1491593A 1993-02-08 1993-02-08
US1491593 1993-02-08
PCT/US1994/000951 WO1994018311A1 (en) 1993-02-08 1994-01-26 Process for growing porcine reproductive and respiratory syndrome virus and its use in vaccines
US9400951 1994-01-26

Publications (3)

Publication Number Publication Date
FI953731A FI953731A (fi) 1995-08-04
FI953731A0 FI953731A0 (fi) 1995-08-04
FI117513B true FI117513B (fi) 2006-11-15

Family

ID=21768529

Family Applications (1)

Application Number Title Priority Date Filing Date
FI953731A FI117513B (fi) 1993-02-08 1995-08-04 Menetelmä PRRS-viruksen viljelemiseksi ja sen käyttö rokotteissa

Country Status (21)

Country Link
US (2) US5510258A (hu)
EP (1) EP0683816B1 (hu)
JP (1) JP3710095B2 (hu)
KR (1) KR100374295B1 (hu)
CN (1) CN1080300C (hu)
AT (1) ATE197314T1 (hu)
AU (1) AU681874B2 (hu)
BG (1) BG63170B1 (hu)
CZ (1) CZ289743B6 (hu)
DE (1) DE69426228T2 (hu)
DK (1) DK0683816T3 (hu)
ES (1) ES2152304T3 (hu)
FI (1) FI117513B (hu)
GR (1) GR3035257T3 (hu)
HU (1) HU218430B (hu)
NO (1) NO317662B1 (hu)
NZ (1) NZ261992A (hu)
PL (1) PL178609B1 (hu)
PT (1) PT683816E (hu)
SK (1) SK98695A3 (hu)
WO (1) WO1994018311A1 (hu)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2107098A2 (en) 2008-03-31 2009-10-07 Metso Power Oy A pyrolysis method in connection with a boiler and a pyrolysis apparatus

Families Citing this family (59)

* Cited by examiner, † Cited by third party
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CA2103460C (en) 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
US5846805A (en) 1991-08-26 1998-12-08 Boehringer Ingelheim Animal Health, Inc. Culture of swine infertility and respiratory syndrome virus in simian cells
US6080570A (en) * 1991-08-26 2000-06-27 Boehringer Ingelheim Vetmedica, Inc. Method of producing a vaccine for Swine Infertility and Respiratory Syndrome
US6042830A (en) * 1992-08-05 2000-03-28 Boehringer Ingelheim Vetmedica, Inc. Viral agent associated with mystery swine disease
US6982160B2 (en) * 1991-08-26 2006-01-03 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions that include SIRS virus
US6773908B1 (en) * 1992-10-30 2004-08-10 Iowa State University Research Foundation, Inc. Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
US6592873B1 (en) 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome
US6380376B1 (en) 1992-10-30 2002-04-30 Iowa State University Research Foundation Proteins encoded by polynucleic acids of porcine reproductive and respiratory syndrome virus (PRRSV)
ES2074950B1 (es) * 1993-09-17 1996-03-16 Iberica Cyanamid Vacuna para la prevencion de la enfermedad reproductiva y respiratoria de la cerda.
US5690940A (en) * 1995-06-21 1997-11-25 Regents Of The University Of Minnesota Low pathogencity PRRS live virus vaccines and methods of preparation thereof
ES2102971B1 (es) * 1996-01-25 1998-03-01 Hipra Lab Sa Nueva cepa atenuada del virus causante del sindrome respiratorio y reproductivo porcino (prrs), las vacunas y medios de diagnostico obtenibles con la misma y los procedimientos para su obtencion.
CN1165342C (zh) * 1996-03-01 2004-09-08 先灵公司 猪生殖和呼吸综合症疫苗
US6015663A (en) * 1996-03-01 2000-01-18 The United States Of America As Represented By The Secretary Of Agriculture Restriction enzyme screen for differentiating porcine reproductive and respiratory syndrome virus strains
US5866401A (en) * 1996-03-01 1999-02-02 Schering Corporation Porcine reproductive and respiratory syndrome vaccine
US5976537A (en) * 1996-07-02 1999-11-02 The United States Of America As Represented By The Secretary Of Agriculture Porcine reproductive and respiratory syndrome vaccine
DK0835930T3 (da) * 1996-10-09 2001-06-18 Akzo Nobel Nv Europæiske vaccinestammer af porcint reproduktions- og respirationssyndrom-virus. (PRRSV)
EP0839912A1 (en) * 1996-10-30 1998-05-06 Instituut Voor Dierhouderij En Diergezondheid (Id-Dlo) Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
US20040224327A1 (en) * 1996-10-30 2004-11-11 Meulenberg Johanna Jacoba Maria Infectious clones of RNA viruses and vaccines and diagnostic assays derived thereof
WO1998035023A1 (en) * 1997-02-07 1998-08-13 Origen, Inc. Method for growing porcine reproductive and respiratory syndrome virus for use as vaccines and diagnostic assays
DE69837992T2 (de) 1997-05-06 2008-03-20 Boehringer Ingelheim Vetmedica Gmbh Prrsv-antigene, die auf peptidsequenzen des prrs-virus basieren, für die verwendung als impfstoff und für diagnostische tests
AU8393398A (en) * 1997-07-10 1999-02-08 Regents Of The University Of Minnesota Causative agent of sow abortion and mortality syndrome (sams), vaccine compositions, antibodies and method
UA78180C2 (uk) 1997-10-03 2007-03-15 Меріаль Кільцевий вірус свині типу ii, вакцини та діагностичні реагенти
FR2772047B1 (fr) * 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
NZ513289A (en) 1998-12-22 2003-04-29 Pfizer Prod Inc Infectious cDNA clone of north american procine reproductive and respiratory syndrome (PRRS) virus and uses thereof
JP3961222B2 (ja) 1999-03-08 2007-08-22 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー Prrsvワクチン
CA2370372C (en) * 1999-04-22 2009-02-24 United States Department Of Agriculture Porcine reproductive and respiratory syndrome vaccine, based on isolate ja-142
US6497883B1 (en) * 1999-06-10 2002-12-24 Merial Porcine circovirus recombinant poxvirus vaccine
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
US6673349B2 (en) * 1999-12-20 2004-01-06 Simon Johannes Barteling Method of inactivating microorganisms
ATE333500T1 (de) * 2000-02-08 2006-08-15 Univ Minnesota Virus des porzinen reproduktiven und respiratorischen syndroms und dessen verwendung
US6740490B2 (en) * 2001-01-29 2004-05-25 Kansas State University Research Foundation Identification and applications of porcine reproductive and respiratory syndrome virus host susceptibility factor(s) for improved swine breeding
US6841364B2 (en) * 2002-01-22 2005-01-11 Protatek International, Inc. Infectious cDNA clones of porcine reproductive and respiratory syndrome virus and expression vectors thereof
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
AR049924A1 (es) 2004-06-18 2006-09-13 Univ Minnesota Identificacion de organismos viralmente infectados y vacunados
US7632636B2 (en) 2004-09-21 2009-12-15 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome isolates and methods of use
ES2733428T3 (es) 2004-12-30 2019-11-29 Boehringer Ingelheim Animal Health Usa Inc Composiciones inmunogénicas frente a PCV2 y métodos para producir composiciones de este tipo
US7691368B2 (en) 2005-04-15 2010-04-06 Merial Limited Vaccine formulations
ES2386973T3 (es) 2005-06-24 2012-09-10 Regents Of The University Of Minnesota Virus PRRS, clones infecciosos, mutantes de los mismos, y métodos de utilización
PL1968630T3 (pl) 2005-12-29 2018-08-31 Boehringer Ingelheim Vetmedica, Inc. Multiwalentne immunogenne kompozycje PCV2
CN100523177C (zh) * 2007-01-09 2009-08-05 中国农业科学院哈尔滨兽医研究所 猪繁殖与呼吸综合症病毒弱毒疫苗株及其应用
AR064888A1 (es) 2007-01-12 2009-04-29 Univ Illinois Celulas no simias para el crecimiento del virus del sindrome reproductor y respiratorio porcino (prrs)
US7666585B2 (en) * 2007-06-15 2010-02-23 Protatek International, Inc. Construction of chimera PRRSV, compositions and vaccine preparations
MX2010000235A (es) * 2007-06-25 2010-08-02 Univ South Dakota Virus del sindrome respiratorio y reproductivo porcino tipo 1 norteamericano recombinante y metodos de uso.
CN101363865B (zh) * 2008-05-26 2013-03-06 北京庄笛浩禾生物医学科技有限公司 一种猪蓝耳病毒胶体金检测试纸条、其制备方法及其应用
MX2011002046A (es) * 2008-08-25 2011-04-21 Boehringer Ingelheim Vetmed Vacuna contra sindrome disgenesico y respiratorio porcino altamente patogeno (hp prrs).
AR078253A1 (es) 2009-09-02 2011-10-26 Boehringer Ingelheim Vetmed Metodos para reducir la actividad antivirica en composiciones pcv-2 y composiciones pcv-2 con mejor inmunogenicidad
SG179037A1 (en) 2009-09-10 2012-04-27 Merial Ltd New vaccine formulations comprising saponin-containing adjuvants
DK2675476T3 (en) 2011-02-17 2015-12-14 Boehringer Ingelheim Vetmed Process for producing PRRSV on a commercial scale
ME02271B (me) 2011-02-17 2016-02-20 Boehringer Ingelheim Vetmedica Gmbh Novi evropski prrsv soj
WO2013017568A1 (en) 2011-07-29 2013-02-07 Boehringer Ingelheim Vetmedica Gmbh INFECTIOUS cDNA CLONE OF EUROPEAN PRRS VIRUS AND USES THEREOF
US9187731B2 (en) 2011-07-29 2015-11-17 Boehringer Ingelheim Vetmedica Gmbh PRRS virus inducing type I interferon in susceptible cells
HUE035774T2 (hu) 2011-08-12 2018-05-28 Merial Inc Biológiai anyagok, különösen oltóanyagok, vákuummal elõsegített tartósítása
EP2929018A4 (en) 2012-12-07 2016-07-13 Univ Illinois PORCINE REPRODUCTIVE AND RESPIRATORY SYNDROME VIRUS COMPOSITION AND USES THEREOF
EP2968513A2 (en) 2013-03-15 2016-01-20 Boehringer Ingelheim Vetmedica, Inc. Porcine reproductive and respiratory syndrome virus, compositions, vaccine and methods of use
JP6821429B2 (ja) 2013-09-25 2021-01-27 ゾエティス・サービシーズ・エルエルシー Pcv2b分岐ワクチン組成物及び使用方法
TWI745278B (zh) 2014-10-10 2021-11-11 以色列商艾畢克生物實驗有限公司 發泡性降低之疫苗組合物
CN104694485A (zh) * 2015-02-13 2015-06-10 广西壮族自治区兽医研究所 Z-ietd-fmk在提高prrsv体外培养滴度方面的应用及其方法
AU2017286727B2 (en) 2016-06-17 2024-02-08 Boehringer Ingelheim Animal Health USA Inc. Novel immunogenic formulations comprising linear or branched polyacrylic acid polymer adjuvants

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US5213795A (en) * 1990-10-24 1993-05-25 Oxford Encephalomyocarditis virus vaccine
CA2103460C (en) * 1991-06-06 2000-09-26 Gert Wensvoort Causative agent of the mystery swine disease, vaccine compositions and diagnostic kits
CA2116348C (en) * 1991-08-26 2001-07-03 James E. Collins Sirs vaccine and diagnosis method
CA2076744C (en) * 1991-08-26 2000-06-27 Danny W. Chladek Viral agent associated with mystery swine disease
WO1993006211A1 (en) * 1991-09-16 1993-04-01 Collins James E Vaccine for mystery swine disease and method for diagnosis thereof
WO1993007898A1 (en) * 1991-10-14 1993-04-29 Akzo Nobel N.V. Porcine reproductive respiratory syndrome vaccine and diagnostic
FR2682966B1 (fr) * 1991-10-29 1994-12-02 Rhone Merieux Preparation d'antigenes et de vaccins du virus de la mystery disease, antigenes et vaccins obtenus pour la prevention de cette maladie.
US5695766A (en) * 1992-10-30 1997-12-09 Iowa State University Research Foundation Highly virulent porcine reproductive and respiratory syndrome viruses which produce lesions in pigs and vaccines that protect pigs against said syndrome

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2107098A2 (en) 2008-03-31 2009-10-07 Metso Power Oy A pyrolysis method in connection with a boiler and a pyrolysis apparatus

Also Published As

Publication number Publication date
BG63170B1 (bg) 2001-05-31
JPH08506486A (ja) 1996-07-16
NZ261992A (en) 1996-06-25
PL310126A1 (en) 1995-11-27
KR100374295B1 (ko) 2003-12-24
ATE197314T1 (de) 2000-11-15
CZ203195A3 (en) 1995-12-13
US5510258A (en) 1996-04-23
PL178609B1 (pl) 2000-05-31
HUT72917A (en) 1996-06-28
FI953731A (fi) 1995-08-04
FI953731A0 (fi) 1995-08-04
WO1994018311A1 (en) 1994-08-18
PT683816E (pt) 2001-03-30
BG99850A (bg) 1996-02-28
AU681874B2 (en) 1997-09-11
ES2152304T3 (es) 2001-02-01
GR3035257T3 (en) 2001-04-30
JP3710095B2 (ja) 2005-10-26
HU9502330D0 (en) 1996-05-28
DE69426228D1 (de) 2000-12-07
NO953091L (no) 1995-08-07
CZ289743B6 (cs) 2002-03-13
HU218430B (hu) 2000-08-28
NO953091D0 (no) 1995-08-07
DE69426228T2 (de) 2001-03-01
US5587164A (en) 1996-12-24
DK0683816T3 (da) 2001-01-08
EP0683816A1 (en) 1995-11-29
CN1117742A (zh) 1996-02-28
AU6128594A (en) 1994-08-29
CN1080300C (zh) 2002-03-06
NO317662B1 (no) 2004-11-29
EP0683816B1 (en) 2000-11-02
SK98695A3 (en) 1996-11-06

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