NO310188B1 - Orto-substituerte benzoylguanidiner, deres fremstilling, deres anvendelse for fremstilling av medikamenter ellerdiagnostika samt medikamenter inneholdende benzoylguanidinene - Google Patents

Orto-substituerte benzoylguanidiner, deres fremstilling, deres anvendelse for fremstilling av medikamenter ellerdiagnostika samt medikamenter inneholdende benzoylguanidinene Download PDF

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Publication number
NO310188B1
NO310188B1 NO19972527A NO972527A NO310188B1 NO 310188 B1 NO310188 B1 NO 310188B1 NO 19972527 A NO19972527 A NO 19972527A NO 972527 A NO972527 A NO 972527A NO 310188 B1 NO310188 B1 NO 310188B1
Authority
NO
Norway
Prior art keywords
formula
atoms
compound
treatment
prophylaxis
Prior art date
Application number
NO19972527A
Other languages
English (en)
Norwegian (no)
Other versions
NO972527D0 (no
NO972527L (no
Inventor
Andreas Weichert
Joachim Brendel
Heinz-Werner Kleemann
Hans Jochen Lang
Jan-Robert Schwark
Udo Albus
Wolfgang Scholz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO972527D0 publication Critical patent/NO972527D0/no
Publication of NO972527L publication Critical patent/NO972527L/no
Publication of NO310188B1 publication Critical patent/NO310188B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
NO19972527A 1996-06-04 1997-06-03 Orto-substituerte benzoylguanidiner, deres fremstilling, deres anvendelse for fremstilling av medikamenter ellerdiagnostika samt medikamenter inneholdende benzoylguanidinene NO310188B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19622370A DE19622370A1 (de) 1996-06-04 1996-06-04 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (3)

Publication Number Publication Date
NO972527D0 NO972527D0 (no) 1997-06-03
NO972527L NO972527L (no) 1997-12-05
NO310188B1 true NO310188B1 (no) 2001-06-05

Family

ID=7796095

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19972527A NO310188B1 (no) 1996-06-04 1997-06-03 Orto-substituerte benzoylguanidiner, deres fremstilling, deres anvendelse for fremstilling av medikamenter ellerdiagnostika samt medikamenter inneholdende benzoylguanidinene

Country Status (29)

Country Link
US (1) US6011063A (cs)
EP (1) EP0811610B1 (cs)
JP (1) JP4101904B2 (cs)
KR (1) KR980002019A (cs)
CN (1) CN1064956C (cs)
AR (1) AR008761A1 (cs)
AT (1) ATE209630T1 (cs)
AU (1) AU723665B2 (cs)
BR (1) BR9703440A (cs)
CA (1) CA2206758C (cs)
CZ (1) CZ289411B6 (cs)
DE (2) DE19622370A1 (cs)
DK (1) DK0811610T3 (cs)
ES (1) ES2166487T3 (cs)
HR (1) HRP970304B1 (cs)
HU (1) HUP9700989A3 (cs)
ID (1) ID17038A (cs)
IL (1) IL120988A0 (cs)
MX (1) MX9704094A (cs)
NO (1) NO310188B1 (cs)
NZ (1) NZ314973A (cs)
PL (1) PL185757B1 (cs)
PT (1) PT811610E (cs)
RU (1) RU2214397C2 (cs)
SI (1) SI0811610T1 (cs)
SK (1) SK282628B6 (cs)
TR (1) TR199700453A2 (cs)
TW (1) TW429243B (cs)
ZA (1) ZA974869B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410563B1 (en) 1999-12-22 2002-06-25 Merck Frosst Canada & Co. Substituted 8-arylquinoline phosphodiesterase-4 inhibitors
US6639077B2 (en) 2000-03-23 2003-10-28 Merck Frosst Canada & Co. Tri-aryl-substituted-ethane PDE4 inhibitors
MY123585A (en) 2000-03-23 2006-05-31 Merck Canada Inc Tri-aryl-substituted-ethane pde4 inhibitors.
AU2001261962B2 (en) 2000-05-25 2005-04-21 Merck Frosst Canada Ltd Fluoroalkoxy-substituted benzamide dichloropyridinyl n-oxide pde4 inhibitor
US6740666B2 (en) 2000-12-20 2004-05-25 Merck & Co., Inc. Substituted 8-arylquinoline phosphodiesterase-4 inhibitors
ES2247325T3 (es) 2001-05-24 2006-03-01 MERCK FROSST CANADA & CO. Inhibidores de 1-biaril-1,8-naftiridin-4-ona fosfodiesterasa-4.
JO2311B1 (en) 2001-08-29 2005-09-12 ميرك فروست كندا ليمتد Alkyl inhibitors Ariel phosphodiesterase-4
JP4493341B2 (ja) 2002-03-12 2010-06-30 メルク・シャープ・エンド・ドーム・コーポレイション 代謝型グルタメート受容体−５の二アリール置換テトラゾールモジュレータ
GB0916163D0 (en) * 2009-09-15 2009-10-28 Shire Llc Prodrugs of guanfacine

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ284456B6 (cs) * 1992-02-15 1998-12-16 Hoechst Aktiengesellschaft Aminosubstituované benzoylguanidiny, způsob jejich přípravy, jejich použití jako léčiv a léčivo, které je obsahuje
DK0612723T3 (da) * 1993-02-20 1998-03-30 Hoechst Ag Substituerede benzoylguanidiner, fremgangsmåde til fremstilling, deres anvendelse som lægemiddel, som inhibitor af den cellulære Na+/H+-udbytning eller som diagnostikum samt lægemiddel med indhold deraf
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4327244A1 (de) * 1993-08-13 1995-02-16 Hoechst Ag Harnstoffsubstituierte Benzoylguandine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4422685A1 (de) * 1994-06-29 1996-01-04 Hoechst Ag Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
ATE209630T1 (de) 2001-12-15
CN1175572A (zh) 1998-03-11
AR008761A1 (es) 2000-02-23
PL185757B1 (pl) 2003-07-31
AU723665B2 (en) 2000-08-31
ES2166487T3 (es) 2002-04-16
SK282628B6 (sk) 2002-10-08
HUP9700989A3 (en) 1998-04-28
SI0811610T1 (en) 2002-04-30
DE19622370A1 (de) 1997-12-11
CA2206758A1 (en) 1997-12-04
PT811610E (pt) 2002-05-31
HUP9700989A2 (en) 1997-12-29
KR980002019A (ko) 1998-03-30
US6011063A (en) 2000-01-04
HRP970304A2 (en) 1998-04-30
TR199700453A2 (xx) 1997-12-21
NZ314973A (en) 1998-09-24
ZA974869B (en) 1997-12-04
DK0811610T3 (da) 2002-03-25
RU2214397C2 (ru) 2003-10-20
IL120988A0 (en) 1997-11-20
CA2206758C (en) 2007-08-14
CN1064956C (zh) 2001-04-25
HU9700989D0 (en) 1997-07-28
JP4101904B2 (ja) 2008-06-18
EP0811610A1 (de) 1997-12-10
DE59705495D1 (de) 2002-01-10
CZ169697A3 (en) 1997-12-17
JPH1067731A (ja) 1998-03-10
AU2465097A (en) 1997-12-11
PL320327A1 (en) 1997-12-08
HRP970304B1 (en) 2002-10-31
EP0811610B1 (de) 2001-11-28
NO972527D0 (no) 1997-06-03
BR9703440A (pt) 1998-09-29
NO972527L (no) 1997-12-05
CZ289411B6 (cs) 2002-01-16
MX9704094A (es) 1997-12-31
TW429243B (en) 2001-04-11
SK69697A3 (en) 1998-01-14
ID17038A (id) 1997-12-04

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