BR9703440A - Benzoilguadinas orto-substituídas processos para sua preparação seu emprego como medicamento ou diagnóstico bem como medicamento contendo as mesmas - Google Patents

Benzoilguadinas orto-substituídas processos para sua preparação seu emprego como medicamento ou diagnóstico bem como medicamento contendo as mesmas

Info

Publication number
BR9703440A
BR9703440A BR9703440A BR9703440A BR9703440A BR 9703440 A BR9703440 A BR 9703440A BR 9703440 A BR9703440 A BR 9703440A BR 9703440 A BR9703440 A BR 9703440A BR 9703440 A BR9703440 A BR 9703440A
Authority
BR
Brazil
Prior art keywords
medicine
benzoylguadines
ortho
diagnosis
substituted
Prior art date
Application number
BR9703440A
Other languages
English (en)
Inventor
Hans-Jochen Lang
Andreas Weichert
Wolfgang Scholz
Udo Albus
Heinz-Werner Kleemann
Jan-Robert Schwark
Joachim Brendel
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9703440A publication Critical patent/BR9703440A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)
BR9703440A 1996-06-04 1997-06-04 Benzoilguadinas orto-substituídas processos para sua preparação seu emprego como medicamento ou diagnóstico bem como medicamento contendo as mesmas BR9703440A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19622370A DE19622370A1 (de) 1996-06-04 1996-06-04 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (1)

Publication Number Publication Date
BR9703440A true BR9703440A (pt) 1998-09-29

Family

ID=7796095

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9703440A BR9703440A (pt) 1996-06-04 1997-06-04 Benzoilguadinas orto-substituídas processos para sua preparação seu emprego como medicamento ou diagnóstico bem como medicamento contendo as mesmas

Country Status (29)

Country Link
US (1) US6011063A (pt)
EP (1) EP0811610B1 (pt)
JP (1) JP4101904B2 (pt)
KR (1) KR980002019A (pt)
CN (1) CN1064956C (pt)
AR (1) AR008761A1 (pt)
AT (1) ATE209630T1 (pt)
AU (1) AU723665B2 (pt)
BR (1) BR9703440A (pt)
CA (1) CA2206758C (pt)
CZ (1) CZ289411B6 (pt)
DE (2) DE19622370A1 (pt)
DK (1) DK0811610T3 (pt)
ES (1) ES2166487T3 (pt)
HR (1) HRP970304B1 (pt)
HU (1) HUP9700989A3 (pt)
ID (1) ID17038A (pt)
IL (1) IL120988A0 (pt)
MX (1) MX9704094A (pt)
NO (1) NO310188B1 (pt)
NZ (1) NZ314973A (pt)
PL (1) PL185757B1 (pt)
PT (1) PT811610E (pt)
RU (1) RU2214397C2 (pt)
SI (1) SI0811610T1 (pt)
SK (1) SK282628B6 (pt)
TR (1) TR199700453A2 (pt)
TW (1) TW429243B (pt)
ZA (1) ZA974869B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6410563B1 (en) 1999-12-22 2002-06-25 Merck Frosst Canada & Co. Substituted 8-arylquinoline phosphodiesterase-4 inhibitors
US6639077B2 (en) 2000-03-23 2003-10-28 Merck Frosst Canada & Co. Tri-aryl-substituted-ethane PDE4 inhibitors
MY123585A (en) 2000-03-23 2006-05-31 Merck Canada Inc Tri-aryl-substituted-ethane pde4 inhibitors.
WO2001090076A1 (en) 2000-05-25 2001-11-29 Merck Frosst Canada & Co. Fluoroalkoxy-substituted benzamide dichloropyridinyl n-oxide pde4 inhibitor
US6740666B2 (en) 2000-12-20 2004-05-25 Merck & Co., Inc. Substituted 8-arylquinoline phosphodiesterase-4 inhibitors
JP4460221B2 (ja) 2001-05-24 2010-05-12 メルク フロスト カナダ リミテツド １−ビアリール−１，８−ナフチリジン−４−オン系ホスホジエステラーゼ−４阻害薬
JO2311B1 (en) 2001-08-29 2005-09-12 ميرك فروست كندا ليمتد Alkyl inhibitors Ariel phosphodiesterase-4
ATE486600T1 (de) 2002-03-12 2010-11-15 Merck Sharp & Dohme Di-aryl-substituierte tetrazol-modulatoren des metabotropen glutamat-rezeptors-5
GB0916163D0 (en) * 2009-09-15 2009-10-28 Shire Llc Prodrugs of guanfacine

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE157351T1 (de) * 1993-02-20 1997-09-15 Hoechst Ag Substituierte benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament, als inhibitoren des zellulären na+/h+-austauschs oder als diagnostikum sowie sie enthaltendes medikament
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4422685A1 (de) * 1994-06-29 1996-01-04 Hoechst Ag Ortho-amino-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
DE19622370A1 (de) 1997-12-11
EP0811610A1 (de) 1997-12-10
SI0811610T1 (en) 2002-04-30
AU2465097A (en) 1997-12-11
US6011063A (en) 2000-01-04
HRP970304A2 (en) 1998-04-30
NZ314973A (en) 1998-09-24
MX9704094A (es) 1997-12-31
TW429243B (en) 2001-04-11
HRP970304B1 (en) 2002-10-31
CN1175572A (zh) 1998-03-11
HUP9700989A3 (en) 1998-04-28
CZ289411B6 (cs) 2002-01-16
PT811610E (pt) 2002-05-31
KR980002019A (ko) 1998-03-30
IL120988A0 (en) 1997-11-20
CN1064956C (zh) 2001-04-25
ID17038A (id) 1997-12-04
AR008761A1 (es) 2000-02-23
ES2166487T3 (es) 2002-04-16
HUP9700989A2 (en) 1997-12-29
ATE209630T1 (de) 2001-12-15
JPH1067731A (ja) 1998-03-10
NO310188B1 (no) 2001-06-05
JP4101904B2 (ja) 2008-06-18
EP0811610B1 (de) 2001-11-28
NO972527L (no) 1997-12-05
CA2206758C (en) 2007-08-14
SK282628B6 (sk) 2002-10-08
CA2206758A1 (en) 1997-12-04
SK69697A3 (en) 1998-01-14
AU723665B2 (en) 2000-08-31
PL320327A1 (en) 1997-12-08
TR199700453A2 (xx) 1997-12-21
PL185757B1 (pl) 2003-07-31
CZ169697A3 (en) 1997-12-17
DE59705495D1 (de) 2002-01-10
DK0811610T3 (da) 2002-03-25
RU2214397C2 (ru) 2003-10-20
ZA974869B (en) 1997-12-04
NO972527D0 (no) 1997-06-03
HU9700989D0 (en) 1997-07-28

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Legal Events

Date Code Title Description
FB34 Technical and formal requirements: requirement - article 34 of industrial property law
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 8A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1834 DE 01/03/2006.