NO149106C - Analogifremgangsmaate for fremstilling av farmakologisk aktive benzcykloamider - Google Patents
Analogifremgangsmaate for fremstilling av farmakologisk aktive benzcykloamiderInfo
- Publication number
- NO149106C NO149106C NO75752220A NO752220A NO149106C NO 149106 C NO149106 C NO 149106C NO 75752220 A NO75752220 A NO 75752220A NO 752220 A NO752220 A NO 752220A NO 149106 C NO149106 C NO 149106C
- Authority
- NO
- Norway
- Prior art keywords
- benzcycloamides
- preparation
- pharmacologically active
- analogy procedure
- analogy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (16)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP49072472A JPS511480A (ja) | 1974-06-24 | 1974-06-24 | Etokishikaruboniruarukokishi 3*44 jihidorokarubosuchirirujudotaino seizoho |
JP49072473A JPS511481A (ja) | 1974-06-24 | 1974-06-24 | Karubokishiarukokishi 3*44 jihidorokarubosuchirirujudotaino seizoho |
JP49077660A JPS516970A (en) | 1974-07-05 | 1974-07-05 | Shianoetokishi 3*44 jihidorokarubosuchirirujudotaino seizoho |
JP49077661A JPS5182279A (en) | 1974-07-05 | 1974-07-05 | Karubokishetokishi 3*44 jihidorokarubosuchirirujudotainoseizoho |
JP49094376A JPS5123271A (ja) | 1974-08-16 | 1974-08-16 | Karubamoiruarukokishi 3*44 jihidorokarubosuchirirujudotaiseizoho |
JP50053027A JPS51128977A (en) | 1975-04-30 | 1975-04-30 | Process for preparing carbostyril derivatives |
JP50053026A JPS51128976A (en) | 1975-04-30 | 1975-04-30 | Process for preparing carbostyril derivatives |
JP50053028A JPS51128978A (en) | 1975-04-30 | 1975-04-30 | Process for preparing carbostyril derivatives |
JP50058134A JPS51133283A (en) | 1975-05-15 | 1975-05-15 | A process for preparing carbostyril derivatives |
JP50058129A JPS51133278A (en) | 1975-05-15 | 1975-05-15 | A process for preparing novel carbostyril derivatives |
JP50058135A JPS51133284A (en) | 1975-05-15 | 1975-05-15 | A process for preparing carbostyril derivatives |
JP50058127A JPS51133276A (en) | 1975-05-15 | 1975-05-15 | Process for preparing carbostyril derivatives |
JP50058128A JPS51133277A (en) | 1975-05-15 | 1975-05-15 | A process for preparing novel carbostyril derivatives |
JP50058874A JPS51136677A (en) | 1975-05-16 | 1975-05-16 | Process for preparation of carbostyril derivatives |
JP50058872A JPS604173B2 (ja) | 1975-05-16 | 1975-05-16 | カルボスチリル誘導体の製法 |
JP50066729A JPS51141864A (en) | 1975-06-02 | 1975-06-02 | Process for preparing oxyindole derivatives. |
Publications (3)
Publication Number | Publication Date |
---|---|
NO752220L NO752220L (hu) | 1975-12-30 |
NO149106B NO149106B (no) | 1983-11-07 |
NO149106C true NO149106C (no) | 1984-02-22 |
Family
ID=27585697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO75752220A NO149106C (no) | 1974-06-24 | 1975-06-23 | Analogifremgangsmaate for fremstilling av farmakologisk aktive benzcykloamider |
Country Status (11)
Country | Link |
---|---|
US (2) | US4070470A (hu) |
CA (1) | CA1048497A (hu) |
CH (1) | CH621339A5 (hu) |
DE (2) | DE2559509C2 (hu) |
DK (1) | DK150155C (hu) |
FI (1) | FI59246C (hu) |
FR (1) | FR2276043A1 (hu) |
GB (1) | GB1505305A (hu) |
IE (1) | IE41172B1 (hu) |
NL (1) | NL162376C (hu) |
NO (1) | NO149106C (hu) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4313947A (en) * | 1974-06-24 | 1982-02-02 | Otsuka Pharmaceutical Co., Ltd. | Platelet aggregation inhibiting 2-oxyindoles, their compositions and method of use |
IE46852B1 (en) * | 1977-06-10 | 1983-10-05 | Otsuka Pharma Co Ltd | Novel carbostyril derivatives |
AT374184B (de) * | 1978-02-17 | 1984-03-26 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen carbostyril- und oxindolderivaten |
SU843739A3 (ru) * | 1978-02-17 | 1981-06-30 | Карл Томэ Гмбх (Фирма) | Способ получени карбостириловыхили ОКСиНдОлОВыХ пРОизВОдНыХ |
AT374185B (de) * | 1978-02-17 | 1984-03-26 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen carbostyril- und oxindolderivaten |
JPS5535019A (en) * | 1978-09-01 | 1980-03-11 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
DE2909035A1 (de) * | 1979-03-08 | 1980-09-18 | Hoechst Ag | 8-oxo-5,6,7,8-tetrahydro-2-chinolon und verfahren zu dessen herstellung |
DE2909779A1 (de) * | 1979-03-13 | 1980-09-18 | Thomae Gmbh Dr K | Neue indolderivate, deren herstellung und deren verwendung als arzneimittel |
AT376209B (de) * | 1979-07-14 | 1984-10-25 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen carbostyrilderivaten |
AT375925B (de) * | 1979-07-14 | 1984-09-25 | Thomae Gmbh Dr K | Verfahren zur herstellung von neuen carbostyrilderivaten |
JPS56122356A (en) | 1980-02-29 | 1981-09-25 | Otsuka Pharmaceut Co Ltd | Carbostyril derivative |
AT383594B (de) * | 1980-02-29 | 1987-07-27 | Otsuka Pharma Co Ltd | Verfahren zum herstellen von neuen carbostyrilderivaten und ihren salzen |
ES8300091A1 (es) * | 1980-06-18 | 1982-10-01 | May & Baker Ltd | Procedimiento para preparar derivados de indol o de indolina |
FI77852C (fi) * | 1981-02-17 | 1989-05-10 | Otsuka Pharma Co Ltd | Foerfarande foer framstaellning av nya, saosom hjaertmediciner anvaendbara substituerade amid- och (maettad heterocykel)karbonylkarbostyrilderivat. |
DE3124699A1 (de) * | 1981-06-24 | 1983-01-13 | Basf Ag, 6700 Ludwigshafen | Neue 2-aryl-3,4-diaza-bicyclo(4.n.0.)alken-(2)-one-(5),verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
US4442111A (en) * | 1981-07-25 | 1984-04-10 | Dr. Karl Thomae Gesellschaft Mit Beschrankter Haftung | Antithrombotic sulfimino and sulfoximino indolinones-2 |
DE3300522A1 (de) * | 1982-01-21 | 1983-07-28 | Sandoz-Patent-GmbH, 7850 Lörrach | 3,3-dialkyl- und 3,3-alkylen-indolinderivate, verfahren zu ihrer herstellung und pharmazeutische praeparate sie enthaltend |
US4578381A (en) * | 1982-07-05 | 1986-03-25 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives |
US4490371A (en) * | 1983-02-16 | 1984-12-25 | Syntex (U.S.A.) Inc. | N,N-Disubstituted-(2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-B]quinazolinyl)oxyalkylamides |
US4551459A (en) * | 1983-02-16 | 1985-11-05 | Syntex (U.S.A.) Inc. | Method of treating heart failure using (2-oxo-1,2,3,5-tetrahydroimidazo-[2,1-b]quinazolinyl)oxyalkylamides |
US4663320A (en) * | 1983-02-16 | 1987-05-05 | Syntex (U.S.A.) Inc. | (2-oxo-1,2,3,5-tetrahydroimidazo[2,1-b]quinoazolinyl)oxyalkylamides, compositions and the use thereof |
DE3310891A1 (de) * | 1983-03-25 | 1984-09-27 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue indolinon-(2)-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte |
DE3317653A1 (de) * | 1983-05-14 | 1984-11-15 | Gödecke AG, 1000 Berlin | 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende |
US4657929A (en) * | 1983-10-25 | 1987-04-14 | Fisons Plc | Compounds |
US4582909A (en) * | 1984-02-02 | 1986-04-15 | Warner-Lambert Company | Benzobicyclic lactam acids and derivatives as cognition activators |
CA1254557A (en) * | 1984-02-15 | 1989-05-23 | Michael C. Venuti | (2-oxo-1,2,3,5-tetrahydroimidazo-(2,1-b) quinazolinyl) oxyalkylamides |
US4670434A (en) * | 1985-11-14 | 1987-06-02 | Syntex (U.S.A.) Inc. | (2-oxo-3-methylene-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolinyl)oxyalkylamides useful as cyclic AMP phosphodiesterase inhibitors |
DK167187A (da) | 1986-04-02 | 1987-10-03 | Otsuka Pharma Co Ltd | Carbostyrilderivater og salte deraf, fremgangsmaade til fremstilling af saadanne forbindelser og laegemiddel indeholdende disse |
DE3803775A1 (de) * | 1988-02-09 | 1989-08-17 | Boehringer Mannheim Gmbh | Neue substituierte lactame, verfahren zu ihrer herstellung und arzneimittel, die diese verbindungen enthalten |
JP2753622B2 (ja) | 1988-05-02 | 1998-05-20 | 大塚製薬株式会社 | カルボスチリル誘導体 |
US5227381A (en) * | 1988-05-02 | 1993-07-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative |
AU653060B2 (en) * | 1991-08-23 | 1994-09-15 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative and platelet agglutination inhibitor |
NZ505921A (en) * | 1998-03-31 | 2003-08-29 | Warner Lambert Co | 1-[5-(2,6-Dimethylpiperidino)pentyl] substituted quinolone serine protease inhibitors and their use for treating thrombin related disorders |
DE19839499A1 (de) * | 1998-08-29 | 2000-03-02 | Merck Patent Gmbh | 2-Oxo-2H-chinolinderivate |
GB201520568D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd | Peptides |
GB201520550D0 (en) | 2015-11-23 | 2016-01-06 | Immunocore Ltd & Adaptimmune Ltd | Peptides |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1216878B (de) * | 1963-04-02 | 1966-05-18 | Cassella Farbwerke Mainkur Ag | Verfahren zur Herstellung von coronargefaesserweiternden Derivaten des 7-Hydroxy-2-oxo-1, 2-dihydrochinolins |
GB1058822A (en) * | 1963-07-30 | 1967-02-15 | Ici Ltd | 3-amino-2-hydroxypropoxy heterocyclic derivatives |
CH489497A (de) * | 1967-01-25 | 1970-04-30 | Geigy Ag J R | Verfahren zur Herstellung von neuen Indolderivaten |
US3749731A (en) * | 1971-07-08 | 1973-07-31 | Warner Lambert Co | 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide |
DE2331223C2 (de) * | 1972-06-19 | 1984-11-22 | Kohjin Co., Ltd., Tokio / Tokyo | S-substituierte-2-Thioadenosine, deren 5'-Monophosphate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten |
CH578526A5 (hu) | 1972-06-23 | 1976-08-13 | Sandoz Ag | |
AR207554A1 (es) * | 1972-12-02 | 1976-10-15 | Otsuka Pharma Co Ltd | Procedimiento para producir derivados de 3-alquil-5-((3,4-dihidro-5-carbostiril)oximetil)-oxazolidinona-(2) |
-
1975
- 1975-06-19 US US05/588,475 patent/US4070470A/en not_active Expired - Lifetime
- 1975-06-19 FI FI751842A patent/FI59246C/fi not_active IP Right Cessation
- 1975-06-23 NL NL7507462.A patent/NL162376C/xx not_active IP Right Cessation
- 1975-06-23 IE IE1392/75A patent/IE41172B1/xx unknown
- 1975-06-23 DE DE2559509A patent/DE2559509C2/de not_active Expired
- 1975-06-23 CH CH815175A patent/CH621339A5/de not_active IP Right Cessation
- 1975-06-23 DK DK283175A patent/DK150155C/da not_active IP Right Cessation
- 1975-06-23 DE DE2527937A patent/DE2527937C2/de not_active Expired
- 1975-06-23 CA CA75229940A patent/CA1048497A/en not_active Expired
- 1975-06-23 GB GB26597/75A patent/GB1505305A/en not_active Expired
- 1975-06-23 NO NO75752220A patent/NO149106C/no unknown
- 1975-06-24 FR FR7519670A patent/FR2276043A1/fr active Granted
-
1977
- 1977-06-15 US US05/806,926 patent/US4216220A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CH621339A5 (hu) | 1981-01-30 |
NL162376C (nl) | 1980-05-16 |
NL162376B (nl) | 1979-12-17 |
NL7507462A (nl) | 1975-12-30 |
DE2527937C2 (de) | 1983-09-08 |
NO149106B (no) | 1983-11-07 |
US4216220A (en) | 1980-08-05 |
DK150155C (da) | 1987-11-09 |
GB1505305A (en) | 1978-03-30 |
FR2276043B1 (hu) | 1978-03-24 |
DE2527937A1 (de) | 1976-01-08 |
DE2559509C2 (de) | 1983-02-17 |
DE2559509A1 (de) | 1976-12-30 |
DK283175A (da) | 1975-12-25 |
FR2276043A1 (fr) | 1976-01-23 |
NO752220L (hu) | 1975-12-30 |
IE41172B1 (en) | 1979-11-07 |
FI751842A (hu) | 1975-12-25 |
US4070470A (en) | 1978-01-24 |
IE41172L (en) | 1975-12-24 |
CA1048497A (en) | 1979-02-13 |
FI59246B (fi) | 1981-03-31 |
DK150155B (da) | 1986-12-22 |
FI59246C (fi) | 1981-07-10 |
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