NO143315C - Analogifremgangsmaate ved fremstilling av farmakologisk aktive bis-imidazol-derivater - Google Patents

Analogifremgangsmaate ved fremstilling av farmakologisk aktive bis-imidazol-derivater

Info

Publication number
NO143315C
NO143315C NO750391A NO750391A NO143315C NO 143315 C NO143315 C NO 143315C NO 750391 A NO750391 A NO 750391A NO 750391 A NO750391 A NO 750391A NO 143315 C NO143315 C NO 143315C
Authority
NO
Norway
Prior art keywords
preparation
pharmacologically active
imidazole derivatives
analogy procedure
active bis
Prior art date
Application number
NO750391A
Other languages
English (en)
Other versions
NO750391L (no
NO143315B (no
Inventor
Graham John Durant
Charon Robin Ganellin
Original Assignee
Smith Kline French Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smith Kline French Lab filed Critical Smith Kline French Lab
Publication of NO750391L publication Critical patent/NO750391L/no
Publication of NO143315B publication Critical patent/NO143315B/no
Publication of NO143315C publication Critical patent/NO143315C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
NO750391A 1974-02-07 1975-02-06 Analogifremgangsmaate ved fremstilling av farmakologisk aktive bis-imidazol-derivater NO143315C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB5596/74A GB1493931A (en) 1974-02-07 1974-02-07 Guanidines isothioureas and thioureas

Publications (3)

Publication Number Publication Date
NO750391L NO750391L (no) 1975-09-01
NO143315B NO143315B (no) 1980-10-06
NO143315C true NO143315C (no) 1981-01-14

Family

ID=9799081

Family Applications (1)

Application Number Title Priority Date Filing Date
NO750391A NO143315C (no) 1974-02-07 1975-02-06 Analogifremgangsmaate ved fremstilling av farmakologisk aktive bis-imidazol-derivater

Country Status (20)

Country Link
US (3) US3968227A (no)
JP (1) JPS5946219B2 (no)
AU (1) AU500729B2 (no)
BE (1) BE824923A (no)
CA (1) CA1062263A (no)
CH (1) CH615916A5 (no)
DE (1) DE2504794A1 (no)
DK (1) DK14475A (no)
ES (2) ES434542A1 (no)
FR (1) FR2260343B1 (no)
GB (1) GB1493931A (no)
HU (1) HU174066B (no)
IE (1) IE40659B1 (no)
IL (1) IL46451A (no)
LU (1) LU71804A1 (no)
NL (1) NL7500977A (no)
NO (1) NO143315C (no)
PL (1) PL98615B1 (no)
SE (1) SE416050B (no)
ZA (1) ZA75180B (no)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1493931A (en) * 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
US4197305A (en) * 1974-02-07 1980-04-08 Smith Kline & French Laboratories Limited Thiazole, isothiazole, oxazole and isoxazole compounds
IL49528A (en) * 1975-05-21 1980-11-30 Smith Kline French Lab Imidazolyl(or thiazolyl)methylthio(or butyl)guanidine or thiourea derivatives,their preparation and pharmaceutical compositions comprising them
US4105770A (en) * 1975-07-31 1978-08-08 Smith Kline & French Laboratories Limited Heterocyclomethylsulphinylethyl derivatives of N-cyanoguanidines, thioureas and 2-amino-1-nitroethylene
US4210652A (en) * 1976-07-28 1980-07-01 Smith Kline & French Laboratories Limited Pharmacologically active 1,3-bis[1-(2-heteroalkylthio)ethylamino)-2-nitrovinyl-1-amino]propane derivatives
ZA774220B (en) * 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
ZA774221B (en) * 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
US4219553A (en) * 1976-07-28 1980-08-26 Smith Kline & French Laboratories Limited Alkoxy pyridyl substituted alkanes
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
NZ186965A (en) 1977-04-20 1980-02-21 Ici Ltd Guanidino derivatives and pharmaceutical compositions
US4200760A (en) * 1978-09-26 1980-04-29 Bristol-Myers Company Imidazolylalkylthioalkylamino-ethylene derivatives
US4309435A (en) 1978-10-16 1982-01-05 Imperial Chemical Industries Ltd. Antisecretory guanidine derivatives and pharmaceutical compositions containing them
FR2446829A1 (fr) 1978-11-16 1980-08-14 Glaxo Group Ltd Derives de polymethylene disubstitues en alpha, omega, procede pour leur preparation et compositions pharmaceutiques les contenant
JPS57102852A (en) * 1980-12-19 1982-06-26 Shionogi & Co Ltd Dicarboxylic acid diamide
CA2927544A1 (en) 2015-04-24 2016-10-24 Wal-Mart Stores, Inc. Method and apparatus for holding containers open
WO2022034121A1 (en) 2020-08-11 2022-02-17 Université De Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB850483A (en) * 1957-10-25 1960-10-05 May & Baker Ltd Improvements in or relating to pyrimidine derivatives
US3622596A (en) * 1960-10-14 1971-11-23 A Wander Sa Dr Carbanilide compounds
DE1214239B (de) * 1960-11-01 1966-04-14 Spofa Sdruzeni Podnikuu Pro Zd Verfahren zur Herstellung von 5-bis-(beta-Chloraethyl)-aminomethyluracil-hydrochlorid
CH405282A (de) * 1961-11-24 1966-01-15 Wander Ag Dr A Verfahren zur Herstellung basischer Verbindungen
US3225047A (en) * 1964-02-24 1965-12-21 Bristol Myers Co N,n'-bis(pyrimidine-5-acetyl)ethylene diamines
CH440252A (de) * 1964-04-24 1967-07-31 Wander Ag Dr A Verfahren zur Herstellung neuer Harnstoffderivate
US3335142A (en) * 1965-07-07 1967-08-08 American Cyanamid Co Process for the preparation of n, n'-disubstituted ureas
US3646049A (en) * 1970-03-05 1972-02-29 Merck & Co Inc Acylaminobenzimidazole derivatives
US4137234A (en) * 1971-03-09 1979-01-30 Smith Kline & French Laboratories Limited Thiazole, isothiazole, oxazole and isoxazole substituted thiourea and urea compounds
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
US3917626A (en) * 1971-03-29 1975-11-04 Ici Ltd 3,6-Dioxa-1,8-octandiamido bis (pyridinium) compounds
GB1339764A (en) * 1971-03-29 1973-12-05 Ici Ltd Pyridine derivatives
GB1493931A (en) * 1974-02-07 1977-11-30 Smith Kline French Lab Guanidines isothioureas and thioureas
US4137319A (en) * 1974-02-07 1979-01-30 Smith Kline & French Laboratories Limited Guanidino, thioureido, isothioureido and nitrovinylamino derivatives of pyridine
US4062967A (en) * 1974-02-07 1977-12-13 Smith Kline & French Laboratories Limited Bis-guanidino-alkane compounds
GB1497260A (en) * 1974-06-28 1978-01-05 Smith Kline French Lab Guanidine derivatives
US4151289A (en) * 1975-01-22 1979-04-24 Smith Kline & French Laboratories Limited Nitromethylene amidino derivatives containing imidazole groups

Also Published As

Publication number Publication date
CA1062263A (en) 1979-09-11
ES434542A1 (es) 1976-12-16
AU500729B2 (en) 1979-05-31
CH615916A5 (no) 1980-02-29
JPS5946219B2 (ja) 1984-11-10
IL46451A0 (en) 1975-04-25
AU7746375A (en) 1976-07-22
NO750391L (no) 1975-09-01
NL7500977A (nl) 1975-08-11
FR2260343A1 (no) 1975-09-05
GB1493931A (en) 1977-11-30
IE40659L (en) 1975-08-07
US3968227A (en) 1976-07-06
FR2260343B1 (no) 1978-07-21
US4578388A (en) 1986-03-25
ES437587A1 (es) 1977-01-16
LU71804A1 (no) 1975-06-24
US4301165A (en) 1981-11-17
ZA75180B (en) 1976-01-28
DK14475A (no) 1975-10-13
DE2504794A1 (de) 1975-08-14
IL46451A (en) 1980-03-31
SE7501208L (no) 1975-08-08
PL98615B1 (pl) 1978-05-31
IE40659B1 (en) 1979-07-18
HU174066B (hu) 1979-10-28
SE416050B (sv) 1980-11-24
NO143315B (no) 1980-10-06
BE824923A (fr) 1975-07-29
JPS50108259A (no) 1975-08-26

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