MXPA06007856A - Anticuerpo monoclonal especifico de factor de estimulacion de colonias de macrofagos (m-csf) y usos del mismo. - Google Patents

Anticuerpo monoclonal especifico de factor de estimulacion de colonias de macrofagos (m-csf) y usos del mismo.

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Publication number
MXPA06007856A
MXPA06007856A MXPA06007856A MXPA06007856A MXPA06007856A MX PA06007856 A MXPA06007856 A MX PA06007856A MX PA06007856 A MXPA06007856 A MX PA06007856A MX PA06007856 A MXPA06007856 A MX PA06007856A MX PA06007856 A MXPA06007856 A MX PA06007856A
Authority
MX
Mexico
Prior art keywords
antibody
cancer
amino acid
seq
csf
Prior art date
Application number
MXPA06007856A
Other languages
English (en)
Spanish (es)
Inventor
Cheng Liu
Deborah Lee Zimmerman
Gregory Martin Harrowe
Kirston Koths
William Michael Kavanaugh
Li Song
Maria Calderon-Cacia
Arnold H Horwitz
Original Assignee
Chiron Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp filed Critical Chiron Corp
Publication of MXPA06007856A publication Critical patent/MXPA06007856A/es

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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/243Colony Stimulating Factors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/662Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/66Phosphorus compounds
    • A61K31/675Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • C07ORGANIC CHEMISTRY
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    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/51Complete heavy chain or Fd fragment, i.e. VH + CH1
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/515Complete light chain, i.e. VL + CL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/52Constant or Fc region; Isotype
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    • C07K2317/00Immunoglobulins specific features
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    • C07K2317/54F(ab')2
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/62Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622Single chain antibody (scFv)
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
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    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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MXPA06007856A 2004-01-07 2005-01-06 Anticuerpo monoclonal especifico de factor de estimulacion de colonias de macrofagos (m-csf) y usos del mismo. MXPA06007856A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US53518104P 2004-01-07 2004-01-07
US57641704P 2004-06-02 2004-06-02
PCT/US2005/000546 WO2005068503A2 (en) 2004-01-07 2005-01-06 M-csf-specific monoclonal antibody and uses thereof

Publications (1)

Publication Number Publication Date
MXPA06007856A true MXPA06007856A (es) 2007-03-23

Family

ID=34798846

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA06007856A MXPA06007856A (es) 2004-01-07 2005-01-06 Anticuerpo monoclonal especifico de factor de estimulacion de colonias de macrofagos (m-csf) y usos del mismo.

Country Status (24)

Country Link
US (6) US20090324604A1 (enExample)
EP (3) EP3476861A1 (enExample)
JP (3) JP5422101B2 (enExample)
KR (2) KR101307868B1 (enExample)
CN (2) CN101189264B (enExample)
AU (1) AU2005205533B2 (enExample)
BR (1) BRPI0506726B8 (enExample)
CA (1) CA2552750C (enExample)
CY (1) CY1121162T1 (enExample)
DK (2) DK2311873T3 (enExample)
EC (1) ECSP066756A (enExample)
ES (2) ES2689328T3 (enExample)
HU (2) HUE039803T2 (enExample)
IL (1) IL176755A (enExample)
LT (1) LT2311873T (enExample)
MX (1) MXPA06007856A (enExample)
NO (1) NO341391B1 (enExample)
NZ (1) NZ548785A (enExample)
PL (2) PL2311873T3 (enExample)
PT (2) PT2311873T (enExample)
RU (2) RU2401277C2 (enExample)
SI (2) SI1704166T1 (enExample)
TR (1) TR201815885T4 (enExample)
WO (1) WO2005068503A2 (enExample)

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WO2005068503A3 (en) 2005-11-10
BRPI0506726A (pt) 2007-05-02
US20160015809A1 (en) 2016-01-21
CN101189264B (zh) 2017-10-10
US20180171009A1 (en) 2018-06-21
LT2311873T (lt) 2018-10-25
EP2311873A1 (en) 2011-04-20
US20140242071A1 (en) 2014-08-28
KR101307868B1 (ko) 2013-09-12
JP5422101B2 (ja) 2014-02-19
CA2552750A1 (en) 2005-07-28
JP2013208125A (ja) 2013-10-10
NZ548785A (en) 2011-08-26
TR201815885T4 (tr) 2018-11-21
EP2311873B1 (en) 2018-08-29
PT2311873T (pt) 2018-11-20
CY1121162T1 (el) 2020-05-29
HK1095841A1 (en) 2007-05-18
ES2689328T3 (es) 2018-11-13
NO20063569L (no) 2006-10-06
EP3476861A1 (en) 2019-05-01
AU2005205533B2 (en) 2012-03-22
PT1704166E (pt) 2015-09-04
RU2006128586A (ru) 2008-02-20
IL176755A (en) 2015-03-31
RU2010121565A (ru) 2011-12-10
EP1704166B1 (en) 2015-04-29
PL2311873T3 (pl) 2019-01-31
US20170152311A1 (en) 2017-06-01
HUE039803T2 (hu) 2019-02-28
KR20070034455A (ko) 2007-03-28
CN107090034B (zh) 2021-10-01
SI2311873T1 (sl) 2018-12-31
WO2005068503A2 (en) 2005-07-28
NO341391B1 (no) 2017-10-30
PL1704166T3 (pl) 2015-10-30
IL176755A0 (en) 2006-10-31
KR101352853B1 (ko) 2014-02-04
JP2011078435A (ja) 2011-04-21
EP1704166A2 (en) 2006-09-27
BRPI0506726B8 (pt) 2021-05-25
HUE026132T2 (en) 2016-05-30
CN107090034A (zh) 2017-08-25
US9926371B2 (en) 2018-03-27
US11034759B2 (en) 2021-06-15
BRPI0506726B1 (pt) 2021-05-11

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