MX9802156A - Composicion de droga de micela copolimerica y metodo para la preparacion de la misma. - Google Patents

Composicion de droga de micela copolimerica y metodo para la preparacion de la misma.

Info

Publication number
MX9802156A
MX9802156A MX9802156A MX9802156A MX9802156A MX 9802156 A MX9802156 A MX 9802156A MX 9802156 A MX9802156 A MX 9802156A MX 9802156 A MX9802156 A MX 9802156A MX 9802156 A MX9802156 A MX 9802156A
Authority
MX
Mexico
Prior art keywords
hydrophobic
drug composition
preparation
poly
micelle drug
Prior art date
Application number
MX9802156A
Other languages
English (en)
Inventor
Sung-Chul Kim
Eun-Ok Chang
In-Suk Song
Chaul-Min Pai
Original Assignee
Sam Yang Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sam Yang Co filed Critical Sam Yang Co
Publication of MX9802156A publication Critical patent/MX9802156A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente invencion se relaciona con un sistema de suministro de droga miscelar que comprende un copolímero de bloque que tiene tanto bloques hidrofobicos como hidrofílico, en donde el bloque hidrofobico es un polímero hidrofobico biodegradable que se selecciona del grupo que consiste de poliláctido, poliglicolido, poli(láctidoglicolido), policaprolactona y derivados de los mismos; y el polímero hidrofobico es poli(oxido de alquileno). Una droga hidrofobica puede incorporarse fácilmente en la micela usando un método sencillo para obtener una composicion de droga terapéuticamente efectiva.
MX9802156A 1995-09-21 1998-03-19 Composicion de droga de micela copolimerica y metodo para la preparacion de la misma. MX9802156A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR1019950030981A KR0180334B1 (ko) 1995-09-21 1995-09-21 블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법

Publications (1)

Publication Number Publication Date
MX9802156A true MX9802156A (es) 1998-11-30

Family

ID=19427413

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9802156A MX9802156A (es) 1995-09-21 1998-03-19 Composicion de droga de micela copolimerica y metodo para la preparacion de la misma.

Country Status (11)

Country Link
US (1) US6322805B1 (es)
EP (1) EP0854731B1 (es)
JP (1) JP3634377B2 (es)
KR (1) KR0180334B1 (es)
CN (1) CN1214818C (es)
AU (1) AU699988B2 (es)
CA (1) CA2231886C (es)
DE (1) DE69625921T2 (es)
ES (1) ES2188787T3 (es)
MX (1) MX9802156A (es)
WO (1) WO1997010849A1 (es)

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US6322805B1 (en) 2001-11-27
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