MX9102582A - Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene. - Google Patents

Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.

Info

Publication number
MX9102582A
MX9102582A MX9102582A MX9102582A MX9102582A MX 9102582 A MX9102582 A MX 9102582A MX 9102582 A MX9102582 A MX 9102582A MX 9102582 A MX9102582 A MX 9102582A MX 9102582 A MX9102582 A MX 9102582A
Authority
MX
Mexico
Prior art keywords
disubstituted
derivatives
indol
procedure
preparation
Prior art date
Application number
MX9102582A
Other languages
English (en)
Inventor
Arnold Keith Dixon
Rudolf Karl Andreas Giger
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909027424A external-priority patent/GB9027424D0/en
Priority claimed from GB909027425A external-priority patent/GB9027425D0/en
Priority claimed from GB919113596A external-priority patent/GB9113596D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of MX9102582A publication Critical patent/MX9102582A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/12—Oxygen atoms acylated by aromatic or heteroaromatic carboxylic acids, e.g. cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
MX9102582A 1990-12-18 1991-12-16 Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene. MX9102582A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909027424A GB9027424D0 (en) 1990-12-18 1990-12-18 Improvements in or relating to organic compounds
GB909027425A GB9027425D0 (en) 1990-12-18 1990-12-18 Improvements in or relating to organic compounds
GB919113596A GB9113596D0 (en) 1991-06-24 1991-06-24 Improvements in or relating to organic compounds

Publications (1)

Publication Number Publication Date
MX9102582A true MX9102582A (es) 1993-01-01

Family

ID=27265408

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9102582A MX9102582A (es) 1990-12-18 1991-12-16 Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.

Country Status (22)

Country Link
US (2) US5272154A (es)
EP (1) EP0491664B1 (es)
JP (1) JP2740777B2 (es)
KR (1) KR920011489A (es)
AT (1) ATE163648T1 (es)
AU (1) AU651640B2 (es)
CA (1) CA2057391A1 (es)
CZ (1) CZ280647B6 (es)
DE (1) DE69129009T2 (es)
DK (1) DK0491664T3 (es)
ES (1) ES2113368T3 (es)
FI (1) FI102069B (es)
GR (1) GR3026506T3 (es)
HU (1) HU211081B (es)
IE (1) IE914387A1 (es)
IL (1) IL100384A (es)
MX (1) MX9102582A (es)
MY (1) MY109983A (es)
NZ (1) NZ240993A (es)
PT (1) PT99829B (es)
SG (1) SG47026A1 (es)
SK (1) SK278597B6 (es)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69111816T4 (de) * 1990-08-31 1996-08-01 Nippon Shinyaku Co Ltd Indolederivate und ihre verwendung als serotonin-antagoniste.
US5654320A (en) * 1995-03-16 1997-08-05 Eli Lilly And Company Indazolecarboxamides
IL117438A (en) * 1995-03-16 2001-12-23 Lilly Co Eli Indazolecarboxamides, their preparation and pharmaceutical compositions containing them
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
RU2183631C2 (ru) * 2000-09-20 2002-06-20 Институт физико-органической химии и углехимии им.Л.М.Литвиненко НАН Украины Способ получения 8-метил-8-азабицикло[3,2,1]окт-3-илового эфира индол-3-карбоновой кислоты
AR036040A1 (es) 2001-06-12 2004-08-04 Upjohn Co Compuestos de heteroarilo multiciclicos sustituidos con quinuclidinas y composiciones farmaceuticas que los contienen
AR036041A1 (es) * 2001-06-12 2004-08-04 Upjohn Co Compuestos aromaticos heterociclicos sustituidos con quinuclidina y composiciones farmaceuticas que los contienen
BR0212477A (pt) * 2001-09-12 2004-08-24 Upjohn Co 7-aza[2.2.1] bicicloheptanos substituìdos para o tratamento de doenças
MXPA04003007A (es) 2001-10-02 2004-07-15 Upjohn Co Compuestos azabiciclico sustituidos condensados con heteroarilo para el tratamiento de enfermedades.
CN1589269A (zh) * 2001-10-26 2005-03-02 康涅狄格大学 杂1,2－二氢化茚:一类新型有效的大麻配体
US6849620B2 (en) 2001-10-26 2005-02-01 Pfizer Inc N-(azabicyclo moieties)-substituted hetero-bicyclic aromatic compounds for the treatment of disease
WO2003042210A1 (en) 2001-11-09 2003-05-22 Pharmacia & Upjohn Company Azabicyclic-phenyl-fused-heterocyclic compounds and their use as alpha7 nachr ligands
WO2003070732A1 (en) * 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Fused bicyclic-n-bridged-heteroaromatic carboxamides for the treatment of disease
WO2003070731A2 (en) * 2002-02-19 2003-08-28 Pharmacia & Upjohn Company Azabicyclic compounds for the treatment of disease
PL210065B1 (pl) 2002-09-25 2011-11-30 Memory Pharm Corp Związki indazole, benzotiazole i benzoizotiazole, kompozycje farmaceutyczne je zawierające oraz zastosowanie związków
JP2006506395A (ja) * 2002-11-01 2006-02-23 ファルマシア・アンド・アップジョン・カンパニー・エルエルシー ＣＮＳ疾患の治療のための、α７ニコチンアゴニスト活性及び５ＨＴ３アンタゴニスト活性を有する化合物
BRPI0417323A (pt) 2003-12-22 2007-03-27 Memory Pharm Corp indóis, 1h-indazóis, 1,2-benzisoxazóis, e 1,2-benzisotiazóis, composto, composição farmacêutica e usos dos mesmos
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
CA2560741C (en) 2004-03-25 2013-08-06 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
JP2007534692A (ja) * 2004-04-22 2007-11-29 メモリー・ファーマシューティカルズ・コーポレイション インドール、１ｈ−インダゾール、１，２−ベンズイソキサゾール、１，２−ベンゾイソチアゾール、ならびにその調製および使用
DE602005027452D1 (de) * 2004-05-07 2011-05-26 Memory Pharm Corp 1h-indazole, benzothiazole, 1,2-benzisoxazole, 1,2-benzisothiazole und chromone und deren herstellung und verwendungen
EP1807423B1 (en) * 2004-11-05 2009-05-20 Theravance, Inc. Quinolinone-carboxamide compounds
ES2332808T3 (es) * 2004-11-05 2010-02-12 Theravance, Inc. Compuestos agonistas del receptor 5-ht4.
AU2005319248A1 (en) * 2004-12-22 2006-06-29 Memory Pharmaceuticals Corporation Nicotinic alpha-7 receptor ligands and preparation and uses thereof
MX2007007818A (es) * 2004-12-22 2007-09-11 Theravance Inc Compuestos de indazol-carboxamida.
ES2523851T3 (es) * 2005-03-02 2014-12-02 Theravance Biopharma R&D Ip, Llc Compuestos de quinolinona como agonistas de los receptores 5-HT4
US8106066B2 (en) * 2005-09-23 2012-01-31 Memory Pharmaceuticals Corporation Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, pyrazolopyridines, isothiazolopyridines, and preparation and uses thereof
DE602008005928D1 (de) * 2007-10-01 2011-05-12 Comentis Inc 1h-indol-3-carbonsäure-chinuclidin-4-ylmethylesterderivate als liganden für den nikotinischen alpha-7-acetylcholinrezeptor zur behandlung von alzheimer-krankheit
JOP20130213B1 (ar) 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
EP3166940A4 (en) 2014-07-11 2018-04-25 Alpharmagen, LLC Quinuclidine compounds for modulating alpha7 -nicotinic acetylcholine receptor activity
ES2883295T3 (es) 2014-09-29 2021-12-07 Takeda Pharmaceuticals Co Forma cristalina de 1-(1-metil-1h-pirazol-4-il)-n-((1r,5s,7s)-9-metil-3-oxa-9-azabiciclo[3.3.1]nonan-7-il)-1h-indol-3-carboxamida

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
DE3587151T2 (de) * 1984-12-20 1993-07-15 Sandoz Ag Behandlung von gastrointestinalkrankheiten durch anwendung von 5-ht3-antagonisten.
GB8623142D0 (en) * 1986-09-26 1986-10-29 Beecham Group Plc Compounds
DE3687080T2 (de) * 1985-04-27 1993-03-25 Beecham Group Plc Azabicyclononyl-indazol-carboxamid mit 5-ht-antagonistischer wirkung.
GB8518658D0 (en) * 1985-07-24 1985-08-29 Glaxo Group Ltd Medicaments
NL8701682A (nl) * 1986-07-30 1988-02-16 Sandoz Ag Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
GR871809B (en) * 1986-11-28 1988-03-07 Glaxo Group Ltd Process for the preparation of tricyclic ketones
US4859662A (en) * 1986-11-28 1989-08-22 Glaxo Group Limited Tetrahydro-imidazolylmethylcarbazolones and analogs thereof for treating 5-HT function disturbances
EP0279990B1 (en) * 1986-12-17 1995-07-12 Glaxo Group Limited Use of heterocyclic derivatives in the treatment of cognitive disorders
EP0278173B1 (en) * 1986-12-17 1993-11-03 Glaxo Group Limited Use of heterocyclic derivatives in the treatment of depressions
GB8701022D0 (en) * 1987-01-19 1987-02-18 Beecham Group Plc Treatment
GB8720693D0 (en) * 1987-09-03 1987-10-07 Glaxo Group Ltd Chemical compounds
JPH01258673A (ja) * 1987-10-22 1989-10-16 Glaxo Group Ltd ケトン誘導体
EP0340270B1 (en) * 1987-11-14 1992-07-15 Beecham Group Plc 5-ht 3? receptor antagonists for treatment of cough and bronchoconstriction
DE3810552A1 (de) * 1988-03-29 1989-10-19 Sandoz Ag Ester und amide von indol-, benzo(b)thiopen-, benzo(b)furancarbonsaeuren oder 4-amino-2-methoxy-benzolsaeuren mit n-heterocyclischen oder n-heterobicyclischen alkoholen oder aminen, verfahren zu deren herstellung sie enthaltende pharmazeutische zusammensetzungen sowie applikator zur verabreichung derselben
DK185489A (da) * 1988-04-22 1989-10-23 Duphar Int Res Imidazolylmethyl-cycloalkanoebaaindoloner, deres fremstilling og anvendelse
US4985422A (en) * 1988-04-27 1991-01-15 Glaxo Group Limited Lactam derivatives
GB8814277D0 (en) * 1988-06-16 1988-07-20 Glaxo Group Ltd Chemical compounds
EP0353983B1 (en) * 1988-08-02 1996-05-29 Glaxo Group Limited Lactam derivatives
FR2639944B1 (fr) * 1988-12-06 1991-01-18 Adir Nouveaux derives de l'indole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
IT1228293B (it) * 1989-02-06 1991-06-07 Angeli Inst Spa Benzoderivati di composti eterociclici contenenti azoto.
GB8904551D0 (en) * 1989-02-28 1989-04-12 Glaxo Group Ltd Chemical compounds
NZ233285A (en) * 1989-04-18 1992-06-25 Duphar Int Res Imidazole-substituted carbamoyl-indoles and condensed analogues thereof and pharmaceutical compositions
GB8916682D0 (en) * 1989-07-21 1989-09-06 Beecham Group Plc Pharmaceutical compounds

Also Published As

Publication number Publication date
FI102069B1 (fi) 1998-10-15
CS381591A3 (en) 1992-07-15
DE69129009D1 (de) 1998-04-09
ES2113368T3 (es) 1998-05-01
ATE163648T1 (de) 1998-03-15
FI915920L (fi) 1992-06-19
HU211081B (en) 1995-10-30
DE69129009T2 (de) 1998-07-23
MY109983A (en) 1997-10-31
SK278597B6 (en) 1997-11-05
JPH04308590A (ja) 1992-10-30
DK0491664T3 (da) 1998-09-28
AU8979191A (en) 1992-06-25
IL100384A0 (en) 1992-09-06
HUT61543A (en) 1993-01-28
KR920011489A (ko) 1992-07-24
US5272154A (en) 1993-12-21
AU651640B2 (en) 1994-07-28
GR3026506T3 (en) 1998-07-31
JP2740777B2 (ja) 1998-04-15
CZ280647B6 (cs) 1996-03-13
FI915920A0 (fi) 1991-12-16
IE914387A1 (en) 1992-07-01
PT99829B (pt) 2000-08-31
HU913792D0 (en) 1992-02-28
IL100384A (en) 1996-05-14
EP0491664B1 (en) 1998-03-04
PT99829A (pt) 1992-12-31
SG47026A1 (en) 1998-03-20
NZ240993A (en) 1994-08-26
CA2057391A1 (en) 1992-06-19
FI102069B (fi) 1998-10-15
EP0491664A1 (en) 1992-06-24
US5543426A (en) 1996-08-06

Similar Documents

Publication Publication Date Title
MX9102582A (es) Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene.
ES2111639T3 (es) Derivados de 3-aminopiperidina y heterociclos relacionados que contienen nitrogeno.
ATE269290T1 (de) Benzoylderivate
DE3576331D1 (de) Tetralin-derivate, ihre herstellung und verwendung.
DE3882614D1 (de) Indol-derivate.
PT97890A (pt) Processo para a preparacao de ftalidas substituidas e de ftalidas heterociclicas
DE69017606D1 (de) Substituierte Cyclohexanole mit zentraler Nervensystemwirkung.
FI920023A0 (fi) Heteroarylpiperazinfoereningar som antipsykotiska aemnen.
MX9201356A (es) Derivados de piperidina, procedimiento para su preparacion y composicion farmaceutica que los contiene.
DK391289D0 (da) Indolderivater
NO941884L (no) 1,3-substituerte cykloalkener og cykloalkaner som sentralnervesystem-midler
ES2174298T3 (es) Derivados de aminotiazol, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
DE59208974D1 (de) Neue pyrazinderivative, ihre herstellung und verwendung
FI925415A0 (fi) Framstaellning av substituerade piperidiner
DK0692484T3 (da) Benzothiadiazinderivat, fremgangsmåde til fremstilling deraf samt farmaceutiske sammensætninger indeholdende derivatet
MX9201382A (es) 6-hetero ciclil -4- amino-1,2,2a,3,4,5- hexa hidro benz- [cd] indoles, procedimiento para su preparacion y composicion farmaceutica que los contiene.
DK0431579T3 (da) Substituerede cyclohexener som midler med virkning på centralnervesystemet
ES2071793T3 (es) Nuevos derivados de la pirrolidona, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
MX10256A (es) Procedimiento para preparar nuevas 3-fenil-7h-tiazolo(3, 2-b) (1, 2, 4) triazin-7-onas.
DK0457215T3 (da) 3-deamino-4-desoxy-4-amino-8-fluoranthracycliner samt fremgangsmåder til fremstilling deraf
ES2101531T3 (es) Derivados de benzo(f)quinoxalinadiona, su preparacion y su utilizacion en medicamentos.
IT1113373B (it) Derivati del 1,5-dimetilbiciclo(3.2.1.)-ottano,preparazione di questi composti e loro impiego come composti per profumi
ES2032838T3 (es) Un procedimiento para preparar derivados tetrahidropirido (1,2-a)indol.
ES2089439T3 (es) Nuevos derivados amidicos de 1-amino-octahidro-pirido-(2,1-c)-(1,4)-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
FR2645538B1 (fr) Trichlorhydrate de (diethylamino-3 propyl)-amino-1 methyl-5 dipyrido (4,3-b) (3,4-f) indole